Cytochrome P450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis

ACS Chemical Biology

Volumn 8, Issue 11, 2013, Pages 2586-2596

  Uhlmann, Stefanie ^a   Süssmuth, Roderich D ^a   Cryle, Max J ^b  

^a TECHNISCHE UNIVERSITÄT BERLIN   (Germany)

^b MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CYCLODEPSIPEPTIDE; CYTOCHROME P450; CYTOCHROME P450 SKY; NONRIBOSOMAL PEPTIDE SYNTHETASE; PEPTIDYL CARRIER PROTEIN; SKYLLAMYCIN; UNCLASSIFIED DRUG; CYCLOPEPTIDE; DEPSIPEPTIDE; HYBRID PROTEIN; PEPTIDE SYNTHASE; RP 1776;

ADENYLATION; ARTICLE; BIOSYNTHESIS; CRYSTAL STRUCTURE; HYDROXYLATION; NONRIBOSOMAL PEPTIDE SYNTHESIS; OXIDATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STEREOCHEMISTRY; CHEMICAL STRUCTURE; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR CLONING; X RAY CRYSTALLOGRAPHY;

CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; DEPSIPEPTIDES; MOLECULAR STRUCTURE; PEPTIDE SYNTHASES; PEPTIDES, CYCLIC; RECOMBINANT FUSION PROTEINS; SUBSTRATE SPECIFICITY;

EID: 84887958896     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb400555e     Document Type: Article

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