X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

Nature

Volumn 521, Issue 7550, 2015, Pages 105-109

  Haslinger, Kristina ^a   Peschke, Madeleine ^a   Brieke, Clara ^a   Maximowitsch, Egle ^a   Cryle, Max J ^a  

^a MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDE; NONRIBOSOMAL PEPTIDE SYNTHETASE; OXYGENASE; TEICOPLANIN; VANCOMYCIN; CYTOCHROME P450; PEPTIDE SYNTHASE; TEICOPLANIN AGLYCONE;

AMINO ACID; ANTIBIOTICS; CYTOCHROME; ENZYME ACTIVITY; METABOLITE; PEPTIDE; SUBSTRATE;

AMINO ACID SUBSTITUTION; APPARENT DISSOCIATION CONSTANT; ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLIZATION; CYCLIZATION; EPIMERIZATION; GLYCOPROTEIN SYNTHESIS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN DOMAIN; RACEMIZATION; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; ANALOGS AND DERIVATIVES; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; GLYCOPEPTIDES; MODELS, MOLECULAR; PEPTIDE SYNTHASES; PROTEIN STRUCTURE, TERTIARY; TEICOPLANIN; VANCOMYCIN;

EID: 84929077444     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature14141     Document Type: Article

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