-
1
-
-
77955384669
-
Microrna-132-mediated loss of p120rasgap activates the endothelium to facilitate pathological angiogenesis
-
Anand S, Majeti BK, Acevedo LM et al (2010) MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis. Nat Med 16:909-914
-
(2010)
Nat Med
, vol.16
, pp. 909-914
-
-
Anand, S.1
Majeti, B.K.2
Acevedo, L.M.3
-
2
-
-
74249084440
-
Mir-15a and mir-16-1 in cancer: Discovery, function and future perspectives
-
Aqeilan RI, Calin GA, Croce CM (2009) miR-15a and miR-16-1 in cancer: discovery, function and future perspectives. Cell Death Differ 17:215-220
-
(2009)
Cell Death Differ
, vol.17
, pp. 215-220
-
-
Aqeilan, R.I.1
Calin, G.A.2
Croce, C.M.3
-
3
-
-
49949116902
-
The impact of micrornas on protein output
-
Baek D, Villen J, Shin C et al (2008) The impact of microRNAs on protein output. Nature 455:64-71
-
(2008)
Nature
, vol.455
, pp. 64-71
-
-
Baek, D.1
Villen, J.2
Shin, C.3
-
4
-
-
77949512140
-
Rna targeting therapeutics: Molecular mechanisms of antisense oligonucleotides as a therapeutic platform
-
Bennett CF, Swayze EE (2010) RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform. Annu Rev Pharmacol Toxicol 50:259-293
-
(2010)
Annu Rev Pharmacol Toxicol
, vol.50
, pp. 259-293
-
-
Bennett, C.F.1
Swayze, E.E.2
-
5
-
-
72149133679
-
Micrornas mir-1, mir-133a, mir-133b and mir- 208 are dysregulated in human myocardial infarction
-
Bostjancic E, Zidar N, Stajer D et al (2010) MicroRNAs miR-1, miR-133a, miR-133b and miR- 208 are dysregulated in human myocardial infarction. Cardiology 115:163-169
-
(2010)
Cardiology
, vol.115
, pp. 163-169
-
-
Bostjancic, E.1
Zidar, N.2
Stajer, D.3
-
6
-
-
33750370444
-
Microrna signatures in human cancers
-
Calin GA, Croce CM (2006) MicroRNA signatures in human cancers. Nat Rev Cancer 6:857-866
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
7
-
-
18744396337
-
Frequent deletions and down-regulation of micro- rna genes mir15 and mir16 at 13q14 in chronic lymphocytic leukemia
-
Calin GA, Dumitru CD, Shimizu M et al (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 99:15524-15529
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15524-15529
-
-
Calin, G.A.1
Dumitru, C.D.2
Shimizu, M.3
-
8
-
-
70349202176
-
Microrna-208a is a regulator of cardiac hypertrophy and conduction in mice
-
Callis TE, Pandya K, Seok HY et al (2009) MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest 119:2772-2786
-
(2009)
J Clin Invest
, vol.119
, pp. 2772-2786
-
-
Callis, T.E.1
Pandya, K.2
Seok, H.Y.3
-
9
-
-
77955661579
-
Microrna-21 in cardiovascular disease
-
Cheng Y, Zhang C (2010) MicroRNA-21 in cardiovascular disease. J Cardiovasc Transl Res 3:251-255
-
(2010)
J Cardiovasc Transl Res
, vol.3
, pp. 251-255
-
-
Cheng, Y.1
Zhang, C.2
-
10
-
-
77954797933
-
Ischaemic preconditioning-regulated mir-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target pdcd4
-
Cheng Y, Zhu P, Yang J et al (2010) Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4. Cardiovasc Res 87:431-439
-
(2010)
Cardiovasc Res
, vol.87
, pp. 431-439
-
-
Cheng, Y.1
Zhu, P.2
Yang, J.3
-
11
-
-
67749132423
-
Argonaute hits-clip decodes microrna-mrna interaction maps
-
Chi SW, Zang JB, Mele A et al (2009) Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature 460:479-486
-
(2009)
Nature
, vol.460
, pp. 479-486
-
-
Chi, S.W.1
Zang, J.B.2
Mele, A.3
-
12
-
-
77952368550
-
Mammalian micrornas: Experimental evaluation of novel and previously annotated genes
-
Chiang HR, Schoenfeld LW, Ruby JG et al (2010) Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev 24:992-1009
-
(2010)
Genes Dev
, vol.24
, pp. 992-1009
-
-
Chiang, H.R.1
Schoenfeld, L.W.2
Ruby, J.G.3
-
13
-
-
35348914716
-
Target protectors reveal dampening and balancing of nodal agonist and antagonist by mir-430
-
Choi WY, Giraldez AJ, Schier AF (2007) Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science 318:271-274
-
(2007)
Science
, vol.318
, pp. 271-274
-
-
Choi, W.Y.1
Giraldez, A.J.2
Schier, A.F.3
-
14
-
-
33646715590
-
Improved targeting of mirna with antisense oligonucleotides
-
Davis S, Lollo B, Freier S et al (2006) Improved targeting of miRNA with antisense oligonucleotides. Nucleic Acids Res 34:2294-2304
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2294-2304
-
-
Davis, S.1
Lollo, B.2
Freier, S.3
-
15
-
-
58549109007
-
Potent inhibition of microrna in vivo without degradation
-
Davis S, Propp S, Freier SM et al (2009) Potent inhibition of microRNA in vivo without degradation. Nucleic Acids Res 37:70-77
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 70-77
-
-
Davis, S.1
Propp, S.2
Freier, S.M.3
-
16
-
-
79551627496
-
A parsimonious model for gene regulation by mirnas
-
Djuranovic S, Nahvi A, Green R (2011) A parsimonious model for gene regulation by miRNAs. Science 331:550-553
-
(2011)
Science
, vol.331
, pp. 550-553
-
-
Djuranovic, S.1
Nahvi, A.2
Green, R.3
-
17
-
-
70350353082
-
Microrna expression signature and the role of microrna- 21 in the early phase of acute myocardial infarction
-
Dong S, Cheng Y, Yang J et al (2009) MicroRNA expression signature and the role of microRNA- 21 in the early phase of acute myocardial infarction. J Biol Chem 284:29514-29525
-
(2009)
J Biol Chem
, vol.284
, pp. 29514-29525
-
-
Dong, S.1
Cheng, Y.2
Yang, J.3
-
18
-
-
79952811715
-
Micrornas in cardiac disease
-
Dorn GW II (2011) MicroRNAs in cardiac disease. Transl Res 157:226-235
-
(2011)
Transl Res
, vol.157
, pp. 226-235
-
-
Dorn, G.1
-
19
-
-
34548316982
-
Microrna sponges: Competitive inhibitors of small rnas in mammalian cells
-
Ebert MS, Neilson JR, Sharp PA (2007) MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Met 4:721-726
-
(2007)
Nat Met
, vol.4
, pp. 721-726
-
-
Ebert, M.S.1
Neilson, J.R.2
Sharp, P.A.3
-
20
-
-
78149303249
-
Microrna sponges: Progress and possibilities
-
Ebert MS, Sharp PA (2010) MicroRNA sponges: progress and possibilities. RNA 16:2043-2050
-
(2010)
RNA
, vol.16
, pp. 2043-2050
-
-
Ebert, M.S.1
Sharp, P.A.2
-
21
-
-
42249093319
-
Lna-mediated microrna silencing in non-human primates
-
Elmen J, Lindow M, Schutz S et al (2008a) LNA-mediated microRNA silencing in non-human primates. Nature 452:896-899
-
(2008)
Nature
, vol.452
, pp. 896-899
-
-
Elmen, J.1
Lindow, M.2
Schutz, S.3
-
22
-
-
40249106014
-
Antagonism of microrna-122 in mice by systemically administered lna-antimir leads to up-regulation of a large set of predicted target mrnas in the liver
-
Elmen J, Lindow M, Silahtaroglu A et al (2008b) Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res 36:1153-1162
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1153-1162
-
-
Elmen, J.1
Lindow, M.2
Silahtaroglu, A.3
-
23
-
-
33645075443
-
Mir-122 regulation of lipid metabolism revealed by in vivo antisense targeting
-
Esau C, Davis S, Murray SF et al (2006) miR-122 regulation of lipid metabolism revealed by in vivo antisense targeting. Cell Metab 3:87-98
-
(2006)
Cell Metab
, vol.3
, pp. 87-98
-
-
Esau, C.1
Davis, S.2
Murray, S.F.3
-
25
-
-
60149095444
-
Most mammalian mrnas are conserved targets of micrornas
-
Friedman RC, Farh KK, Burge CB et al (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 19:92-105
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
-
26
-
-
77957361864
-
Targeting micrornas in cancer: Rationale, strategies and challenges
-
Garzon R, Marcucci G, Croce CM (2010) Targeting microRNAs in cancer: rationale, strategies and challenges. Nat Rev Drug Discov 9:775-789
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 775-789
-
-
Garzon, R.1
Marcucci, G.2
Croce, C.M.3
-
27
-
-
56249131779
-
A rna antagonist of hypoxia-inducible factor- lalpha, ezn-2968, inhibits tumor cell growth
-
Greenberger LM, Horak ID, Filpula D et al (2008) A RNA antagonist of hypoxia-inducible factor- lalpha, EZN-2968, inhibits tumor cell growth. Mol Cancer Ther 7:3598-3608
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3598-3608
-
-
Greenberger, L.M.1
Horak, I.D.2
Filpula, D.3
-
28
-
-
27744537851
-
Human risc couples microrna biogenesis and posttranscriptional gene silencing
-
Gregory RI, Chendrimada TP, Cooch N et al (2005) Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell 123:631-640
-
(2005)
Cell
, vol.123
, pp. 631-640
-
-
Gregory, R.I.1
Chendrimada, T.P.2
Cooch, N.3
-
29
-
-
9144225636
-
The microprocessor complex mediates the genesis of micrornas
-
Gregory RI, K-p Y, Amuthan G et al (2004) The microprocessor complex mediates the genesis of microRNAs. Nature 432:235-240
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Amuthan, G.2
-
31
-
-
34250805982
-
Microrna targeting specificity in mammals: Determinants beyond seed pairing
-
Grimson A, Farh KK-H, Johnston WK et al (2007) MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27:91-105
-
(2007)
Mol Cell
, vol.27
, pp. 91-105
-
-
Grimson, A.1
Farh, K.-H.2
Johnston, W.K.3
-
32
-
-
34447115822
-
The multifunctional rna-binding protein hnrnp a1 is required for processing of mir-18a
-
Guil S, Caceres JF (2007) The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol 14:591-596
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 591-596
-
-
Guil, S.1
Caceres, J.F.2
-
33
-
-
77955644289
-
Mammalian micrornas predominantly act to decrease target mrna levels
-
Guo H, Ingolia NT, Weissman JS et al (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466:835-840
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
-
34
-
-
77950498821
-
Serum microrna signatures identified in a genome-wide serum microrna expression profiling predict survival of non-small-cell lung cancer
-
Hu Z, Chen X, Zhao Y et al (2010) Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol 28:1721-1726
-
(2010)
J Clin Oncol
, vol.28
, pp. 1721-1726
-
-
Hu, Z.1
Chen, X.2
Zhao, Y.3
-
35
-
-
19344378192
-
Sequence-specific inhibition of small rna function
-
Hutvagner G, Simard MJ, Mello CC et al (2004) Sequence-specific inhibition of small RNA function. PLoS Biol 2:E98
-
(2004)
Plos Biol
, vol.2
-
-
Hutvagner, G.1
Simard, M.J.2
Mello, C.C.3
-
36
-
-
79957613439
-
Mir-495 is upregulated by e12/e47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of e-cadherin and redd1
-
Hwang-Verslues WW, Chang PH, Wei PC et al (2011) miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene 30:2463-2474
-
(2011)
Oncogene
, vol.30
, pp. 2463-2474
-
-
Hwang-Verslues, W.W.1
Chang, P.H.2
Wei, P.C.3
-
37
-
-
24644483623
-
Modulation of hepatitis c virus rna abundance by a liver-specific microrna
-
Jopling CL, Yi M, Lancaster AM et al (2005) Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science 309:1577-1581
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
-
38
-
-
79959479529
-
Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes
-
Koller E, Vincent TM, Chappell A et al (2011) Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes. Nucleic Acids Res 39:4795-4807
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 4795-4807
-
-
Koller, E.1
Vincent, T.M.2
Chappell, A.3
-
39
-
-
66449136951
-
Therapeutic microrna delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O’Donnell KA et al (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137:1005-1017
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O’Donnell, K.A.3
-
40
-
-
34250679405
-
Specificity, duplex degradation and subcellular localization of antagomirs
-
Krutzfeldt J, Kuwajima S, Braich R et al (2007) Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Res 35:2885-2892
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 2885-2892
-
-
Krutzfeldt, J.1
Kuwajima, S.2
Braich, R.3
-
41
-
-
28444469246
-
Silencing of micrornas in vivo with’antagomirs’
-
Krutzfeldt J, Rajewsky N, Braich R et al (2005) Silencing of microRNAs in vivo with’antagomirs’. Nature 438:685-689
-
(2005)
Nature
, vol.438
, pp. 685-689
-
-
Krutzfeldt, J.1
Rajewsky, N.2
Braich, R.3
-
42
-
-
0036567147
-
Design of antisense oligonucleotides stabilized by locked nucleic acids
-
Kurreck J, Wyszko E, Gillen C et al (2002) Design of antisense oligonucleotides stabilized by locked nucleic acids. Nucleic Acids Res 30:1911-1918
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 1911-1918
-
-
Kurreck, J.1
Wyszko, E.2
Gillen, C.3
-
43
-
-
33749479908
-
Downregulation of mir-122 in the rodent and human hepatocellular carcinomas
-
Kutay H, Bai S, Datta J et al (2006) Downregulation of miR-122 in the rodent and human hepatocellular carcinomas. J Cell Biochem 99:671-678
-
(2006)
J Cell Biochem
, vol.99
, pp. 671-678
-
-
Kutay, H.1
Bai, S.2
Datta, J.3
-
44
-
-
74249112787
-
Therapeutic silencing of microrna-122 in primates with chronic hepatitis c virus infection
-
Lanford RE, Hildebrandt-Eriksen ES, Petri A et al (2010) Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327:198-201
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
-
45
-
-
77957820261
-
Rnai and small interfering rnas in human disease therapeutic applications
-
Lares MR, Rossi JJ, Ouellet DL (2010) RNAi and small interfering RNAs in human disease therapeutic applications. Trends Biotechnol 28:570-579
-
(2010)
Trends Biotechnol
, vol.28
, pp. 570-579
-
-
Lares, M.R.1
Rossi, J.J.2
Ouellet, D.L.3
-
46
-
-
0027751663
-
The c. Elegans heterochronic gene lin-4 encodes small rnas with antisense complementarity to lin-14
-
Lee RC, Feinbaum RL, Ambros V (1993) The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75:843-854
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
47
-
-
77955469975
-
A direct comparison of anti-microrna oligonucleotide potency
-
Lennox KA, Behlke MA (2010) A direct comparison of anti-microRNA oligonucleotide potency. PharmRes 27:1788-1799
-
(2010)
Pharmres
, vol.27
, pp. 1788-1799
-
-
Lennox, K.A.1
Behlke, M.A.2
-
48
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microrna targets
-
Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120:15-20
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
49
-
-
0346094457
-
Prediction of mammalian microrna targets
-
Lewis BP, Shih IH, Jones-Rhoades MW et al (2003) Prediction of mammalian microRNA targets. Cell 115:787-798
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
-
50
-
-
33947721625
-
Mir-181a is an intrinsic modulator of t cell sensitivity and selection
-
Li Q-J, Chau J, Ebert PJR et al (2007) miR-181a is an intrinsic modulator of T cell sensitivity and selection. Cell 129:147-161
-
(2007)
Cell
, vol.129
, pp. 147-161
-
-
Li, Q.-J.1
Chau, J.2
Ebert, P.3
-
51
-
-
13944282215
-
Microarray analysis shows that some micrornas downregulate large numbers of target mrnas
-
Lim LP, Lau NC, Garrett-Engele P et al (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433:769-773
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
-
52
-
-
69949099167
-
Changes in microrna profile and effects of mir-320 in insulin-resistant 3t3-l1 adipocytes
-
Ling HY, Ou HS, Feng SD et al (2009) Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Clin Exp Pharmacol Physiol 36:E32-E39
-
(2009)
Clin Exp Pharmacol Physiol
, vol.36
, pp. E32-E39
-
-
Ling, H.Y.1
Ou, H.S.2
Feng, S.D.3
-
53
-
-
77951919333
-
Microrna regulatory networks in cardiovascular development
-
Liu N, Olson EN (2010) MicroRNA regulatory networks in cardiovascular development. Dev Cell 18:510-525
-
(2010)
Dev Cell
, vol.18
, pp. 510-525
-
-
Liu, N.1
Olson, E.N.2
-
54
-
-
20444460289
-
Microrna expression profiles classify human cancers
-
Lu J, Getz G, Miska EA et al (2005) MicroRNA expression profiles classify human cancers. Nature 435:834-838
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
-
55
-
-
1242318826
-
Sequence-specific inhibition of microrna- and sirna-induced rna silencing
-
Meister G (2004) Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10:544-550
-
(2004)
RNA
, vol.10
, pp. 544-550
-
-
Meister, G.1
-
56
-
-
55049119136
-
Posttranscriptional regulation of mirnas harboring conserved terminal loops
-
Michlewski G, Guil S, Semple CA et al (2008) Posttranscriptional regulation of miRNAs harboring conserved terminal loops. Mol Cell 32:383-393
-
(2008)
Mol Cell
, vol.32
, pp. 383-393
-
-
Michlewski, G.1
Guil, S.2
Semple, C.A.3
-
57
-
-
79959958736
-
Functional evidence that drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microrna profiles
-
Muralidhar B, Winder D, Murray M et al (2011) Functional evidence that Drosha overexpression in cervical squamous cell carcinoma affects cell phenotype and microRNA profiles. J Pathol 224:496-507
-
(2011)
J Pathol
, vol.224
, pp. 496-507
-
-
Muralidhar, B.1
Winder, D.2
Murray, M.3
-
58
-
-
77950822671
-
Single-nucleotide polymorphisms inside microrna target sites influence tumor susceptibility
-
Nicoloso MS, Sun H, Spizzo R et al (2010) Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res 70:2789-2798
-
(2010)
Cancer Res
, vol.70
, pp. 2789-2798
-
-
Nicoloso, M.S.1
Sun, H.2
Spizzo, R.3
-
59
-
-
35548996307
-
Determinants of targeting by endogenous and exogenous micrornas and sirnas
-
Nielsen CB, Shomron N, Sandberg R et al (2007) Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA 13:1894-1910
-
(2007)
RNA
, vol.13
, pp. 1894-1910
-
-
Nielsen, C.B.1
Shomron, N.2
Sandberg, R.3
-
60
-
-
41149130219
-
Sustained expression of microrna-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O’Connell RM, Rao DS, Chaudhuri AA et al (2008) Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 205:585-594
-
(2008)
J Exp Med
, vol.205
, pp. 585-594
-
-
O’Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
-
61
-
-
33846845071
-
Microrna-155 is induced during the macrophage inflammatory response
-
O’Connell RM, Taganov KD, Boldin MP et al (2007) MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci USA 104:1604-1609
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 1604-1609
-
-
O’Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
-
62
-
-
77955591555
-
Micrornas and their target gene networks in breast cancer
-
O’Day E, Lal A (2010) MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res 12:201
-
(2010)
Breast Cancer Res
, vol.12
, pp. 201
-
-
O’Day, E.1
Lal, A.2
-
63
-
-
79953202455
-
Silencing of microrna families by seed-targeting tiny lnas
-
Obad S, dos Santos CO, Petri A et al (2011) Silencing of microRNA families by seed-targeting tiny LNAs. Nat Genet 43:371-378
-
(2011)
Nat Genet
, vol.43
, pp. 371-378
-
-
Obad, S.1
Dos Santos, C.O.2
Petri, A.3
-
64
-
-
33646027887
-
Lna-modified oligonucleotides mediate specific inhibition of microrna function
-
Orom UA, Kauppinen S, Lund AH (2006) LNA-modified oligonucleotides mediate specific inhibition of microRNA function. Gene 372:137-141
-
(2006)
Gene
, vol.372
, pp. 137-141
-
-
Orom, U.A.1
Kauppinen, S.2
Lund, A.H.3
-
65
-
-
0037089589
-
Short hairpin rnas (Shrnas) induce sequence- specific silencing in mammalian cells
-
Paddison PJ, Caudy AA, Bernstein E et al (2002) Short hairpin RNAs (shRNAs) induce sequence- specific silencing in mammalian cells. Genes Dev 16:948-958
-
(2002)
Genes Dev
, vol.16
, pp. 948-958
-
-
Paddison, P.J.1
Caudy, A.A.2
Bernstein, E.3
-
66
-
-
77955890374
-
Defective erythroid differentiation in mir-451 mutant mice mediated by 14-3-3zeta
-
Patrick DM, Zhang CC, Tao Y et al (2010) Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta. Genes Dev 24:1614-1619
-
(2010)
Genes Dev
, vol.24
, pp. 1614-1619
-
-
Patrick, D.M.1
Zhang, C.C.2
Tao, Y.3
-
67
-
-
77952585703
-
Micrornas as a molecular basis for mental retardation, alzheimer’s and prion diseases
-
Provost P (2010) MicroRNAs as a molecular basis for mental retardation, Alzheimer’s and prion diseases. Brain Res 1338:58-66
-
(2010)
Brain Res
, vol.1338
, pp. 58-66
-
-
Provost, P.1
-
68
-
-
67649783639
-
Expression of mir-21 and its targets (Pten, pdcd4, tm1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma
-
Qi L, Bart J, Tan L et al (2009) Expression of miR-21 and its targets (PTEN, PDCD4, TM1) in flat epithelial atypia of the breast in relation to ductal carcinoma in situ and invasive carcinoma. BMC Cancer 9:163
-
(2009)
BMC Cancer
, vol.9
, pp. 163
-
-
Qi, L.1
Bart, J.2
Tan, L.3
-
69
-
-
79960015327
-
Antagonism of mir-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
-
Rayner KJ, Sheedy FJ, Esau CC et al (2011) Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis. J Clin Invest 121:2921-2931
-
(2011)
J Clin Invest
, vol.121
, pp. 2921-2931
-
-
Rayner, K.J.1
Sheedy, F.J.2
Esau, C.C.3
-
70
-
-
79961027715
-
Microrna pharmacogenomics: Post-transcriptional regulation of drug response
-
Rukov JL, Shomron N (2011) MicroRNA pharmacogenomics: post-transcriptional regulation of drug response. Trends Mol Med 17:412-423
-
(2011)
Trends Mol Med
, vol.17
, pp. 412-423
-
-
Rukov, J.L.1
Shomron, N.2
-
71
-
-
77951627045
-
Expression of microrna-208 is associated with adverse clinical outcomes in human dilated cardiomyopathy
-
Satoh M, Minami Y, Takahashi Y et al (2010) Expression of microRNA-208 is associated with adverse clinical outcomes in human dilated cardiomyopathy. J Card Fail 16:404-410
-
(2010)
J Card Fail
, vol.16
, pp. 404-410
-
-
Satoh, M.1
Minami, Y.2
Takahashi, Y.3
-
72
-
-
49949117302
-
Widespread changes in protein synthesis induced by micrornas
-
Selbach M, Schwanhausser B, Thierfelder N et al (2008) Widespread changes in protein synthesis induced by microRNAs. Nature 455:58-63
-
(2008)
Nature
, vol.455
, pp. 58-63
-
-
Selbach, M.1
Schwanhausser, B.2
Thierfelder, N.3
-
74
-
-
70350004858
-
An evolutionary perspective of animal micrornas and their targets
-
Shomron N, Golan D, Hornstein E (2009) An evolutionary perspective of animal microRNAs and their targets. J Biomed Biotechnol 2009:594-738
-
(2009)
J Biomed Biotechnol
, vol.2009
, pp. 594-738
-
-
Shomron, N.1
Golan, D.2
Hornstein, E.3
-
75
-
-
39749110083
-
Small non-coding rnas in animal development
-
Stefani G, Slack FJ (2008) Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 9:219-230
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 219-230
-
-
Stefani, G.1
Slack, F.J.2
-
76
-
-
75649138331
-
Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents
-
Stein CA, Hansen JB, Lai J et al (2010) Efficient gene silencing by delivery of locked nucleic acid antisense oligonucleotides, unassisted by transfection reagents. Nucleic Acids Res 38:e3
-
(2010)
Nucleic Acids Res
, vol.38
-
-
Stein, C.A.1
Hansen, J.B.2
Lai, J.3
-
77
-
-
74149083873
-
Systemic delivery of synthetic microrna-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
-
Takeshita F, Patrawala L, Osaki M et al (2010) Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 18:181-187
-
(2010)
Mol Ther
, vol.18
, pp. 181-187
-
-
Takeshita, F.1
Patrawala, L.2
Osaki, M.3
-
78
-
-
79952789910
-
Induction of mir-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells
-
Terao M, Fratelli M, Kurosaki M et al (2011) Induction of miR-21 by retinoic acid in estrogen receptor-positive breast carcinoma cells. J Biol Chem 286:4027-4042
-
(2011)
J Biol Chem
, vol.286
, pp. 4027-4042
-
-
Terao, M.1
Fratelli, M.2
Kurosaki, M.3
-
79
-
-
57749168828
-
Microrna-21 contributes to myocardial disease by stimulating map kinase signalling in fibroblasts
-
Thum T, Gross C, Fiedler J et al (2008) MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456:980-984
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
-
80
-
-
79959845414
-
Micrornas 103 and 107 regulate insulin sensitivity
-
Trajkovski M, Hausser J, Soutschek J et al (2011) MicroRNAs 103 and 107 regulate insulin sensitivity. Nature 474:649-653
-
(2011)
Nature
, vol.474
, pp. 649-653
-
-
Trajkovski, M.1
Hausser, J.2
Soutschek, J.3
-
81
-
-
79957900919
-
Systemic delivery of tumor suppressor microrna mimics using a neutral lipid emulsion inhibits lung tumors in mice
-
Trang P, Wiggins JF, Daige CL et al (2011) Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther 19:1116-1122
-
(2011)
Mol Ther
, vol.19
, pp. 1116-1122
-
-
Trang, P.1
Wiggins, J.F.2
Daige, C.L.3
-
82
-
-
71549165765
-
A family of micrornas encoded by myosin genes governs myosin expression and muscle performance
-
van Rooij E, Quiat D, Johnson BA et al (2009) A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell 17:662-673
-
(2009)
Dev Cell
, vol.17
, pp. 662-673
-
-
Van Rooij, E.1
Quiat, D.2
Johnson, B.A.3
-
83
-
-
33845317603
-
A signature pattern of stress-responsive micrornas that can evoke cardiac hypertrophy and heart failure
-
van Rooij E, Sutherland LB, Liu N et al (2006) A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci USA 103:18255-18260
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 18255-18260
-
-
Van Rooij, E.1
Sutherland, L.B.2
Liu, N.3
-
84
-
-
34247589595
-
Control of stress-dependent cardiac growth and gene expression by a microrna
-
van Rooij E, Sutherland LB, Qi X et al (2007) Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 316:575-579
-
(2007)
Science
, vol.316
, pp. 575-579
-
-
Van Rooij, E.1
Sutherland, L.B.2
Qi, X.3
-
85
-
-
51349141401
-
Dysregulation of micrornas after myocardial infarction reveals a role of mir-29 in cardiac fibrosis
-
van Rooij E, Sutherland LB, Thatcher JE et al (2008) Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci USA 105:13027-13032
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 13027-13032
-
-
Van Rooij, E.1
Sutherland, L.B.2
Thatcher, J.E.3
-
86
-
-
54549119169
-
Nf-kappab-yy1-mir-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma
-
Wang H, Garzon R, Sun H et al (2008) NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell 14:369-381
-
(2008)
Cancer Cell
, vol.14
, pp. 369-381
-
-
Wang, H.1
Garzon, R.2
Sun, H.3
-
87
-
-
0027730383
-
Posttranscriptional regulation of the heterochronic gene lin- 14 by lin-4 mediates temporal pattern formation in c. Elegans
-
Wightman B, Ha I, Ruvkun G (1993) Posttranscriptional regulation of the heterochronic gene lin- 14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75:855-862
-
(1993)
Cell
, vol.75
, pp. 855-862
-
-
Wightman, B.1
Ha, I.2
Ruvkun, G.3
-
88
-
-
34347381752
-
Novel approaches for gene-specific interference via manipulating actions of micrornas: Examination on the pacemaker channel genes hcn2 and hcn4
-
Xiao J, Yang B, Lin H et al (2007) Novel approaches for gene-specific interference via manipulating actions of microRNAs: examination on the pacemaker channel genes HCN2 and HCN4. J Cell Phys 212:285-292
-
(2007)
J Cell Phys
, vol.212
, pp. 285-292
-
-
Xiao, J.1
Yang, B.2
Lin, H.3
-
89
-
-
40749111551
-
A skin microrna promotes differentiation by repressing’sternness’
-
Yi R, Poy MN, Stoffel M, Fuchs E (2008) A skin microRNA promotes differentiation by repressing’sternness’. Nature 452:225-229
-
(2008)
Nature
, vol.452
, pp. 225-229
-
-
Yi, R.1
Poy, M.N.2
Stoffel, M.3
Fuchs, E.4
-
90
-
-
63649126549
-
A novel role of microrna in late preconditioning
-
Yin C, Salloum FN, Kukreja RC (2009) A novel role of microRNA in late preconditioning. Circ Res 104:572-575
-
(2009)
Circ Res
, vol.104
, pp. 572-575
-
-
Yin, C.1
Salloum, F.N.2
Kukreja, R.C.3
-
91
-
-
33847338002
-
Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotide, isis 301012, targeting human apolipo- protein b-100
-
Yu RZ, Kim TW, Hong A et al (2007) Cross-species pharmacokinetic comparison from mouse to man of a second-generation antisense oligonucleotide, ISIS 301012, targeting human apolipo- protein B-100. Drug Metab Dispos 35:460-468
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 460-468
-
-
Yu, R.Z.1
Kim, T.W.2
Hong, A.3
-
92
-
-
0036294527
-
Both natural and designed micro rnas can inhibit the expression of cognate mrnas when expressed in human cells
-
Zeng Y, Wagner EJ, Cullen BR (2002) Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 9:1327-1333
-
(2002)
Mol Cell
, vol.9
, pp. 1327-1333
-
-
Zeng, Y.1
Wagner, E.J.2
Cullen, B.R.3
-
93
-
-
0041691111
-
Micrornas and small interfering rnas can inhibit mrna expression by similar mechanisms
-
Zeng Y, Yi R, Cullen BR (2003) MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 100:9779-9784
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9779-9784
-
-
Zeng, Y.1
Yi, R.2
Cullen, B.R.3
|