메뉴 건너뛰기




Volumn 119, Issue 9, 2009, Pages 2772-2786

MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 40; GAP JUNCTION PROTEIN; HORMONE BINDING PROTEIN; MICRORNA; MICRORNA 208A; MYOSIN HEAVY CHAIN; MYOSTATIN 2; THYROID HORMONE ASSOCIATED PROTEIN 1; TRANSCRIPTION FACTOR GATA 4; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 70349202176     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI36154     Document Type: Article
Times cited : (736)

References (83)
  • 1
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: Are the answers in sight?
    • Filipowicz, W., Bhattacharyya, S.N., and Sonenberg, N. 2008. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9:102-114.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 3
  • 6
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. 2004. The functions of animal microRNAs. Nature. 431:350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 7
    • 33748928159 scopus 로고    scopus 로고
    • The Diverse Functions of MicroRNAs in Animal Development and Disease
    • DOI 10.1016/j.devcel.2006.09.009, PII S1534580706004023
    • Kloosterman, W.P., and Plasterk, R.H. 2006. The diverse functions of microRNAs in animal development and disease. Dev. Cell. 11:441-450. (Pubitemid 44430905)
    • (2006) Developmental Cell , vol.11 , Issue.4 , pp. 441-450
    • Kloosterman, W.P.1    Plasterk, R.H.A.2
  • 8
    • 44649106334 scopus 로고    scopus 로고
    • Taking microRNAs to heart
    • Callis, T.E., and Wang, D.Z. 2008. Taking microRNAs to heart. Trends Mol. Med. 14:254-260.
    • (2008) Trends Mol. Med. , vol.14 , pp. 254-260
    • Callis, T.E.1    Wang, D.Z.2
  • 11
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • DOI 10.1038/nature03817
    • Zhao, Y., Samal, E., and Srivastava, D. 2005. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature. 436:214-220. (Pubitemid 41021266)
    • (2005) Nature , vol.436 , Issue.7048 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 14
    • 41149147013 scopus 로고    scopus 로고
    • Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure
    • Chen, J.F., et al. 2008. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. U. S. A. 105:2111-2116.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 2111-2116
    • Chen, J.F.1
  • 16
    • 33845317603 scopus 로고    scopus 로고
    • A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure
    • van Rooij, E., et al. 2006. A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc. Natl. Acad. Sci. U. S. A. 103:18255-18260.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 18255-18260
    • Van Rooij, E.1
  • 17
    • 34247589595 scopus 로고    scopus 로고
    • Control of stress-dependent cardiac growth and gene expression by a microRNA
    • van Rooij, E., et al. 2007. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science. 316:575-579.
    • (2007) Science , vol.316 , pp. 575-579
    • Van Rooij, E.1
  • 18
    • 0021153417 scopus 로고
    • Expression of the cardiac ventricular alpha-and beta-myosin heavy chain genes is developmentally and hormonally regulated
    • Lompre, A.M., Nadal-Ginard, B., and Mahdavi, V. 1984. Expression of the cardiac ventricular alphaand beta-myosin heavy chain genes is developmentally and hormonally regulated. J. Biol. Chem. 259:6437-6446. (Pubitemid 14108193)
    • (1984) Journal of Biological Chemistry , vol.259 , Issue.10 , pp. 6437-6446
    • Lompre, A.-M.1    Nadal-Ginard, B.2    Mahdavi, V.3
  • 19
    • 0034648805 scopus 로고    scopus 로고
    • Genomic circuits and the integrative biology of cardiac diseases
    • Chien, K.R. 2000. Genomic circuits and the integrative biology of cardiac diseases. Nature. 407:227-232.
    • (2000) Nature , vol.407 , pp. 227-232
    • Chien, K.R.1
  • 20
    • 1842579393 scopus 로고    scopus 로고
    • Hypertrophy of the Heart: A New Therapeutic Target?
    • DOI 10.1161/01.CIR.0000120390.68287.BB
    • Frey, N., Katus, H.A., Olson, E.N., and Hill, J.A. 2004. Hypertrophy of the heart: a new therapeutic target? Circulation. 109:1580-1589. (Pubitemid 38451712)
    • (2004) Circulation , vol.109 , Issue.13 , pp. 1580-1589
    • Frey, N.1    Katus, H.A.2    Olson, E.N.3    Hill, J.A.4
  • 22
    • 34748888492 scopus 로고    scopus 로고
    • Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure
    • DOI 10.1016/j.yjmcc.2007.07.045, PII S0022282807011571
    • Gupta, M.P. 2007. Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure. J. Mol. Cell. Cardiol. 43:388-403. (Pubitemid 47469981)
    • (2007) Journal of Molecular and Cellular Cardiology , vol.43 , Issue.4 , pp. 388-403
    • Gupta, M.P.1
  • 23
    • 0028143517 scopus 로고
    • Regulated expression of foreign genes in vivo after germline transfer
    • Passman, R.S., and Fishman, G.I. 1994. Regulated expression of foreign genes in vivo after germline transfer. J. Clin. Invest. 94:2421-2425.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2421-2425
    • Passman, R.S.1    Fishman, G.I.2
  • 24
    • 0034649248 scopus 로고    scopus 로고
    • Congestive heart failure: Fifty years of progress
    • Braunwald, E., and Bristow, M.R. 2000. Congestive heart failure: fifty years of progress. Circulation. 102:IV14-IV23.
    • (2000) Circulation , vol.102
    • Braunwald, E.1    Bristow, M.R.2
  • 26
    • 34447318648 scopus 로고    scopus 로고
    • MicroRNAs are aberrantly expressed in hypertrophic heart: Do they play a pole in cardiac hypertrophy?
    • DOI 10.2353/ajpath.2007.061170
    • Cheng, Y., et al. 2007. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am. J. Pathol. 170:1831-1840. (Pubitemid 47339258)
    • (2007) American Journal of Pathology , vol.170 , Issue.6 , pp. 1831-1840
    • Cheng, Y.1    Ji, R.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 27
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNAs play an essential role in the development of cardiac hypertrophy
    • DOI 10.1161/01.RES.0000257913.42552.23, PII 0000301220070216000016
    • Sayed, D., Hong, C., Chen, I.Y., Lypowy, J., and Abdellatif, M. 2007. MicroRNAs play an essential role in the development of cardiac hypertrophy. Circ. Res. 100:416-424. (Pubitemid 46272414)
    • (2007) Circulation Research , vol.100 , Issue.3 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.-Y.3    Lypowy, J.4    Abdellatif, M.5
  • 29
    • 0034095174 scopus 로고    scopus 로고
    • Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects
    • Tardiff, J.C., et al. 2000. Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects. Am. J. Physiol. Heart Circ. Physiol. 278:H412-H419.
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.278
    • Tardiff, J.C.1
  • 30
    • 10644275373 scopus 로고    scopus 로고
    • Impact of beta-myosin heavy chain expression on cardiac function during stress
    • DOI 10.1016/j.jacc.2004.09.044, PII S0735109704019278
    • Krenz, M., and Robbins, J. 2004. Impact of beta-myosin heavy chain expression on cardiac function during stress. J. Am. Coll. Cardiol. 44:2390-2397. (Pubitemid 39647615)
    • (2004) Journal of the American College of Cardiology , vol.44 , Issue.12 , pp. 2390-2397
    • Krenz, M.1    Robbins, J.2
  • 31
    • 33750932583 scopus 로고    scopus 로고
    • Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hyperthrophy and normal aging in vivo
    • DOI 10.1073/pnas.0607700103
    • Pandya, K., Kim, H.S., and Smithies, O. 2006. Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo. Proc. Natl. Acad. Sci. U. S. A. 103:16864-16869. (Pubitemid 44737344)
    • (2006) Proceedings of the National Academy of Sciences of the United States of America , vol.103 , Issue.45 , pp. 16864-16869
    • Pandya, K.1    Kim, H.-S.2    Smithies, O.3
  • 33
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B.P., Burge, C.B., and Bartel, D.P. 2005. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 120:15-20.
    • (2005) Cell. , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 34
    • 0027161712 scopus 로고
    • Regulation of myosin heavy chain genes in the heart
    • Morkin, E. 1993. Regulation of myosin heavy chain genes in the heart. Circulation. 87:1451-1460. (Pubitemid 23133087)
    • (1993) Circulation , vol.87 , Issue.5 , pp. 1451-1460
    • Morkin, E.1
  • 35
    • 0034665404 scopus 로고    scopus 로고
    • Control of cardiac myosin heavy chain gene expression
    • DOI 10.1002/1097-0029(20000915)50:6<522::AID-JEMT9>3.0.CO;2-U
    • Morkin, E. 2000. Control of cardiac myosin heavy chain gene expression. Microsc. Res. Tech. 50:522-531. (Pubitemid 30738002)
    • (2000) Microscopy Research and Technique , vol.50 , Issue.6 , pp. 522-531
    • Morkin, E.1
  • 36
    • 8444243360 scopus 로고    scopus 로고
    • Regulation of muscle mass by myostatin
    • Lee, S.J. 2004. Regulation of muscle mass by myostatin. Annu Rev Cell Dev. Biol. 20:61-86.
    • (2004) Annu Rev Cell Dev. Biol. , vol.20 , pp. 61-86
    • Lee, S.J.1
  • 38
    • 33746199834 scopus 로고    scopus 로고
    • Myostatin regulates cardiomyocyte growth through modulation of Akt signaling
    • Morissette, M.R., et al. 2006. Myostatin regulates cardiomyocyte growth through modulation of Akt signaling. Circ. Res. 99:15-24.
    • (2006) Circ. Res. , vol.99 , pp. 15-24
    • Morissette, M.R.1
  • 39
    • 0037151101 scopus 로고    scopus 로고
    • Transcriptional effects of chronic Akt activation in the heart
    • DOI 10.1074/jbc.M201462200
    • Cook, S.A., Matsui, T., Li, L., and Rosenzweig, A. 2002. Transcriptional effects of chronic Akt activation in the heart. J. Biol. Chem. 277:22528-22533. (Pubitemid 34967227)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.25 , pp. 22528-22533
    • Cook, S.A.1    Matsui, T.2    Li, N.3    Rosenzweig, A.4
  • 40
    • 33748707456 scopus 로고    scopus 로고
    • Myostatin expression in ventricular myocardium in a rat model of volume-overload heart failure
    • DOI 10.1111/j.1365-2362.2006.01718.x
    • Shyu, K.G., Lu, M.J., Wang, B.W., Sun, H.Y., and Chang, H. 2006. Myostatin expression in ventricular myocardium in a rat model of volume-overload heart failure. Eur. J. Clin. Invest. 36:713-719. (Pubitemid 44393930)
    • (2006) European Journal of Clinical Investigation , vol.36 , Issue.10 , pp. 713-719
    • Shyu, K.G.1    Lu, M.J.2    Wang, B.W.3    Sun, H.Y.4    Chang, H.5
  • 41
    • 27644464752 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes
    • DOI 10.1016/j.cardiores.2005.06.028, PII S0008636305003317
    • Shyu, K.G., Ko, W.H., Yang, W.S., Wang, B.W., and Kuan, P. 2005. Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes. Cardiovasc. Res. 68:405-414. (Pubitemid 41566560)
    • (2005) Cardiovascular Research , vol.68 , Issue.3 , pp. 405-414
    • Shyu, K.-G.1    Ko, W.-H.2    Yang, W.-S.3    Wang, B.-W.4    Kuan, P.5
  • 42
  • 43
    • 3142698697 scopus 로고    scopus 로고
    • The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis
    • DOI 10.1074/jbc.M401242200
    • Wang, J.C., Walker, A., Blackwell, T.K., and Yamamoto, K.R. 2004. The Caenorhabditis elegans ortholog of TRAP240, CeTRAP240/let-19, selectively modulates gene expression and is essential for embryogenesis. J. Biol. Chem. 279:29270-29277. (Pubitemid 38915803)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.28 , pp. 29270-29277
    • Wang, J.-C.1    Walker, A.2    Blackwell, T.K.3    Yamamoto, K.R.4
  • 45
    • 0032562150 scopus 로고    scopus 로고
    • Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle
    • Kaprielian, R.R., et al. 1998. Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle. Circulation. 97:651-660.
    • (1998) Circulation , vol.97 , pp. 651-660
    • Kaprielian, R.R.1
  • 47
    • 0029801693 scopus 로고    scopus 로고
    • Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy
    • Sepp, R., Severs, N.J., and Gourdie, R.G. 1996. Altered patterns of cardiac intercellular junction distribution in hypertrophic cardiomyopathy. Heart. 76:412-417. (Pubitemid 26390797)
    • (1996) Heart , vol.76 , Issue.5 , pp. 412-417
    • Sepp, R.1    Severs, N.J.2    Gourdie, R.G.3
  • 48
    • 0034283053 scopus 로고    scopus 로고
    • Role of gap junctions in cardiac conduction and development: Insights from the connexin knockout mice
    • Lo, C.W. 2000. Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice. Circ. Res. 87:346-348.
    • (2000) Circ. Res. , vol.87 , pp. 346-348
    • Lo, C.W.1
  • 49
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon, A.M., Goodenough, D.A., and Paul, D.L. 1998. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr. Biol. 8:295-298.
    • (1998) Curr. Biol. , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 50
    • 0030983063 scopus 로고    scopus 로고
    • Slow ventricular conduction in mice heterozygous for a connexin43 null mutation
    • Guerrero, P.A., et al. 1997. Slow ventricular conduction in mice heterozygous for a connexin43 null mutation. J. Clin. Invest. 99:1991-1998.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1991-1998
    • Guerrero, P.A.1
  • 51
    • 0030248881 scopus 로고    scopus 로고
    • Connexins in mammalian heart function
    • Gros, D.B., and Jongsma, H.J. 1996. Connexins in mammalian heart function. Bioessays. 18:719-730.
    • (1996) Bioessays , vol.18 , pp. 719-730
    • Gros, D.B.1    Jongsma, H.J.2
  • 52
    • 18044375365 scopus 로고    scopus 로고
    • Homeobox protein Hop functions in the adult cardiac conduction system
    • Ismat, F.A., et al. 2005. Homeobox protein Hop functions in the adult cardiac conduction system. Circ. Res. 96:898-903.
    • (2005) Circ. Res. , vol.96 , pp. 898-903
    • Ismat, F.A.1
  • 53
    • 0035876125 scopus 로고    scopus 로고
    • Purkinje fibers of the avian heart express a myogenic transcription factor program distinct from cardiac and skeletal muscle
    • DOI 10.1006/dbio.2001.0270
    • Takebayashi-Suzuki, K., Pauliks, L.B., Eltsefon, Y., and Mikawa, T. 2001. Purkinje fibers of the avian heart express a myogenic transcription factor program distinct from cardiac and skeletal muscle. Dev. Biol. 234:390-401. (Pubitemid 32552667)
    • (2001) Developmental Biology , vol.234 , Issue.2 , pp. 390-401
    • Takebayashi-Suzuki, K.1    Pauliks, L.B.2    Eltsefon, Y.3    Mikawa, T.4
  • 54
    • 8644260044 scopus 로고    scopus 로고
    • Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5
    • Linhares, V.L., et al. 2004. Transcriptional regulation of the murine Connexin40 promoter by cardiac factors Nkx2-5, GATA4 and Tbx5. Cardiovasc. Res. 64:402-411.
    • (2004) Cardiovasc. Res. , vol.64 , pp. 402-411
    • Linhares, V.L.1
  • 57
    • 0028983138 scopus 로고
    • Cardiac V1 and V3 myosins differ in their hydrolytic and mechanical activities in vitro
    • VanBuren, P., Harris, D.E., Alpert, N.R., and Warshaw, D.M. 1995. Cardiac V1 and V3 myosins differ in their hydrolytic and mechanical activities in vitro. Circ. Res. 77:439-444.
    • (1995) Circ. Res. , vol.77 , pp. 439-444
    • VanBuren, P.1    Harris, D.E.2    Alpert, N.R.3    Warshaw, D.M.4
  • 59
    • 0242585474 scopus 로고    scopus 로고
    • Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype
    • Abraham, W.T., et al. 2002. Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype. Mol. Med. 8:750-760.
    • (2002) Mol. Med. , vol.8 , pp. 750-760
    • Abraham, W.T.1
  • 60
    • 0037007679 scopus 로고    scopus 로고
    • Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents
    • Lowes, B.D., et al. 2002. Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. N. Engl. J. Med. 346:1357-1365.
    • (2002) N. Engl. J. Med. , vol.346 , pp. 1357-1365
    • Lowes, B.D.1
  • 61
    • 0346334589 scopus 로고    scopus 로고
    • Changes in Myocardial Gene Expression Associated with beta-Blocker Therapy in Patients with Chronic Heart Failure
    • DOI 10.1016/S1071-9164(03)00581-5
    • Yasumura, Y., Takemura, K., Sakamoto, A., Kitakaze, M., and Miyatake, K. 2003. Changes in myocardial gene expression associated with beta-blocker therapy in patients with chronic heart failure. J. Card. Fail. 9:469-474. (Pubitemid 38055656)
    • (2003) Journal of Cardiac Failure , vol.9 , Issue.6 , pp. 469-474
    • Yasumura, Y.1    Takemura, K.2    Sakamoto, A.3    Kitakaze, M.4    Miyatake, K.5
  • 62
    • 39149097822 scopus 로고    scopus 로고
    • Proteasome inhibition promotes regression of left ventricular hypertrophy
    • Stansfield, W.E., et al. 2008. Proteasome inhibition promotes regression of left ventricular hypertrophy. Am. J. Physiol. Heart Circ. Physiol. 294:H645-H650.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.294
    • Stansfield, W.E.1
  • 66
    • 0030885926 scopus 로고    scopus 로고
    • Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts
    • Chang, K.C., et al. 1997. Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat hearts. J. Clin. Invest. 100:1742-1749.
    • (1997) J. Clin. Invest. , vol.100 , pp. 1742-1749
    • Chang, K.C.1
  • 67
    • 0029933730 scopus 로고    scopus 로고
    • Cardiac hypertrophy as a result of long-term thyroxine therapy and thyrotoxicosis
    • Ching, G.W., et al. 1996. Cardiac hypertrophy as a result of long-term thyroxine therapy and thyrotoxicosis. Heart. 75:363-368.
    • (1996) Heart , vol.75 , pp. 363-368
    • Ching, G.W.1
  • 68
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein, E., and Shomron, N. 2006. Canalization of development by microRNAs. Nat. Genet. 38(Suppl.):S20-S24.
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL.
    • Hornstein, E.1    Shomron, N.2
  • 69
    • 33846609167 scopus 로고    scopus 로고
    • Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate
    • DOI 10.1038/ng1953, PII NG1953
    • Flynt, A.S., Li, N., Thatcher, E.J., Solnica-Krezel, L., and Patton, J.G. 2007. Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate. Nat. Genet. 39:259-263. (Pubitemid 46184359)
    • (2007) Nature Genetics , vol.39 , Issue.2 , pp. 259-263
    • Flynt, A.S.1    Li, N.2    Thatcher, E.J.3    Solnica-Krezel, L.4    Patton, J.G.5
  • 70
    • 18244385475 scopus 로고    scopus 로고
    • MicroRNAs regulate brain morphogenesis in zebrafish
    • Giraldez, A.J., et al. 2005. MicroRNAs regulate brain morphogenesis in zebrafish. Science. 308:833-838.
    • (2005) Science , vol.308 , pp. 833-838
    • Giraldez, A.J.1
  • 71
    • 33846135109 scopus 로고    scopus 로고
    • MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development
    • DOI 10.1101/gad.1500707
    • Boutz, P.L., Chawla, G., Stoilov, P., and Black, D.L. 2007. MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development. Genes Dev. 21:71-84. (Pubitemid 46089709)
    • (2007) Genes and Development , vol.21 , Issue.1 , pp. 71-84
    • Boutz, P.L.1    Chawla, G.2    Stoilov, P.3    Black, D.L.4
  • 72
    • 49949116902 scopus 로고    scopus 로고
    • The impact of microRNAs on protein output
    • Baek, D., et al. 2008. The impact of microRNAs on protein output. Nature. 455:64-71.
    • (2008) Nature , vol.455 , pp. 64-71
    • Baek, D.1
  • 73
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • Selbach, M., et al. 2008. Widespread changes in protein synthesis induced by microRNAs. Nature. 455:58-63.
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1
  • 77
    • 2442651359 scopus 로고    scopus 로고
    • A decade of discoveries in cardiac biology
    • Olson, E.N. 2004. A decade of discoveries in cardiac biology. Nat. Med. 10:467-474.
    • (2004) Nat. Med. , vol.10 , pp. 467-474
    • Olson, E.N.1
  • 78
    • 33749361499 scopus 로고    scopus 로고
    • Gene regulatory networks in the evolution and development of the heart
    • DOI 10.1126/science.1132292
    • Olson, E.N. 2006. Gene regulatory networks in the evolution and development of the heart. Science. 313:1922-1927. (Pubitemid 44497993)
    • (2006) Science , vol.313 , Issue.5795 , pp. 1922-1927
    • Olson, E.N.1
  • 81
    • 27944454815 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes
    • DOI 10.1161/01.RES.0000190670.92879.7d
    • Callis, T.E., Cao, D., and Wang, D.Z. 2005. Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circ. Res. 97:992-1000. (Pubitemid 41668912)
    • (2005) Circulation Research , vol.97 , Issue.10 , pp. 992-1000
    • Callis, T.E.1    Cao, D.2    Wang, D.-Z.3
  • 82
    • 34250777057 scopus 로고    scopus 로고
    • Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections
    • DOI 10.1038/nprot.2007.153, PII NPROT.2007.153
    • Obernosterer, G., Martinez, J., and Alenius, M. 2007. Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections. Nat. Protoc. 2:1508-1514. (Pubitemid 46952329)
    • (2007) Nature Protocols , vol.2 , Issue.6 , pp. 1508-1514
    • Obernosterer, G.1    Martinez, J.2    Alenius, M.3
  • 83
    • 0023680529 scopus 로고
    • The effects of triiodothyronine on cultured neonatal rat cardiac myocytes
    • DOI 10.1016/S0022-2828(88)80014-2
    • Williams, H.M., and Ianuzzo, C.D. 1988. The effects of triiodothyronine on cultured neonatal rat cardiac myocytes. J. Mol. Cell. Cardiol. 20:689-699. (Pubitemid 18239705)
    • (1988) Journal of Molecular and Cellular Cardiology , vol.20 , Issue.8 , pp. 689-699
    • Williams, H.M.1    Ianuzzo, C.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.