PINK1/Parkin-mediated mitophagy play a protective role in manganese induced apoptosis in SH-SY5Y cells

Toxicology in Vitro

Volumn 34, Issue , 2016, Pages 212-219

  Zhang, Hong Tao ^a   Mi, Lan ^a,b   Wang, Ting ^a,c   Yuan, Lan ^a   Li, Xue Hui ^a   Dong, Li Sha ^a   Zhao, Peng ^a   Fu, Juan Ling ^a   Yao, Bi Yun ^a   Zhou, Zong Can ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b PEKING UNIVERSITY   (China)

^c CHINA US HENAN HORMEL CANCER INSTITUTE   (China)

Author keywords

Manganese; Mitophagy; Parkin; PINK1; SH SY5Y cell

Indexed keywords

MANGANESE CHLORIDE; PARKIN; PHOSPHOTRANSFERASE; PTEN INDUCED KINASE 1; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MANGANESE; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

ACIDITY; APOPTOSIS; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; GENETIC TRANSFECTION; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOPHAGY; NERVE CELL NECROSIS; NERVE CELL STIMULATION; NEUROPROTECTION; PROTEIN EXPRESSION; SH SY5Y CELL; WESTERN BLOTTING; CELL DEATH; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TUMOR CELL LINE;

APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; HUMANS; MANGANESE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL DEGRADATION; PROTEIN KINASES; REACTIVE OXYGEN SPECIES; UBIQUITIN-PROTEIN LIGASES;

EID: 84973137670     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2016.04.006     Document Type: Article

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