PINK1-Parkin Pathway Activity Is Regulated by Degradation of PINK1 in the Mitochondrial Matrix

PLoS Genetics

Volumn 10, Issue 5, 2014, Pages

  Thomas, Ruth E ^a   Andrews, Laurie A ^a   Burman, Jonathon L ^a   Lin, Wen Yang ^a   Pallanck, Leo J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; ENDOPEPTIDASE LA; PARKIN; PINK1 PROTEIN; UNCLASSIFIED DRUG; DROSOPHILA PROTEIN; PINK1 PROTEIN, DROSOPHILA; PROTEIN SERINE THREONINE KINASE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INACTIVATION; ENZYME LOCALIZATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STABILITY; FEMALE; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UNFOLDED PROTEIN RESPONSE; ANIMAL; GENETICS; METABOLISM; MITOCHONDRION; MUTATION; PARKINSON DISEASE; PATHOLOGY; PROTEIN DEGRADATION;

ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MUTATION; PARKINSON DISEASE; PROTEASE LA; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; UNFOLDED PROTEIN RESPONSE;

EID: 84901615924     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004279     Document Type: Article

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