메뉴 건너뛰기




Volumn 91, Issue , 2016, Pages 1-10

Indoles - A promising scaffold for drug development

Author keywords

2 arylindoles; Bioactive molecules; Design new therapeutics; Heterocycles; Marketed drugs; Natural alkaloids

Indexed keywords

ALKALOID; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ANTIDIABETIC AGENT; ANTIHISTAMINIC AGENT; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; ANTIOXIDANT; ANTIPARKINSON AGENT; ANTIVIRUS AGENT; HETEROCYCLIC COMPOUND; HYPOCHOLESTEROLEMIC AGENT; INDOLE DERIVATIVE;

EID: 84973106784     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2016.05.025     Document Type: Review
Times cited : (518)

References (66)
  • 2
    • 0037567394 scopus 로고    scopus 로고
    • Indole and isatin oximes: Synthesis, reactions and biological activity
    • E. Abele, R. Abele, O. Dzenitis, and E. Lukevics Indole and isatin oximes: synthesis, reactions and biological activity Chem. Heterocycl. Compd. 39 1 2003 3 35
    • (2003) Chem. Heterocycl. Compd. , vol.39 , Issue.1 , pp. 3-35
    • Abele, E.1    Abele, R.2    Dzenitis, O.3    Lukevics, E.4
  • 5
    • 0034849563 scopus 로고    scopus 로고
    • Pharmacology of penile erection
    • K.E. Andersson Pharmacology of penile erection Pharmacol. Rev. 53 3 2001 417 450
    • (2001) Pharmacol. Rev. , vol.53 , Issue.3 , pp. 417-450
    • Andersson, K.E.1
  • 7
    • 0032742725 scopus 로고    scopus 로고
    • Indole amide derivatives: Synthesis, structure-activity relationships and molecular modeling studies of a new series of histamine H1-receptor antagonists
    • S. Battaglia, E. Boldrini, F.D. Settimo, G. Dondio, C.L. Motta, A.M. Marini, and G. Primofiore Indole amide derivatives: synthesis, structure-activity relationships and molecular modeling studies of a new series of histamine H1-receptor antagonists Eur. J. Med. Chem. 34 2 1999 93 105
    • (1999) Eur. J. Med. Chem. , vol.34 , Issue.2 , pp. 93-105
    • Battaglia, S.1    Boldrini, E.2    Settimo, F.D.3    Dondio, G.4    Motta, C.L.5    Marini, A.M.6    Primofiore, G.7
  • 8
    • 0029988128 scopus 로고    scopus 로고
    • New indole derivatives as ACAT inhibitors: Synthesis and structure-activity relationships
    • R. Bellimin, A. Decerprit, and D. Festal New indole derivatives as ACAT inhibitors: synthesis and structure-activity relationships Eur. J. Med. Chem. 31 2 1996 123 132
    • (1996) Eur. J. Med. Chem. , vol.31 , Issue.2 , pp. 123-132
    • Bellimin, R.1    Decerprit, A.2    Festal, D.3
  • 9
    • 64549158645 scopus 로고    scopus 로고
    • The expanded biology of serotonin
    • M. Berger, J.A. Gray, and B.L. Roth The expanded biology of serotonin Annu. Rev. Med. 60 1 2009 355 366
    • (2009) Annu. Rev. Med. , vol.60 , Issue.1 , pp. 355-366
    • Berger, M.1    Gray, J.A.2    Roth, B.L.3
  • 12
    • 84865770185 scopus 로고    scopus 로고
    • A series of 2-arylamino-5-(indolyl)-1,3,4-thiadiazoles as potent cytotoxic agents
    • N. Dalip Kumar, M. Kumar, B. Noel, and K. Shah A series of 2-arylamino-5-(indolyl)-1,3,4-thiadiazoles as potent cytotoxic agents Eur. J. Med. Chem. 55 1 2012 432 438
    • (2012) Eur. J. Med. Chem. , vol.55 , Issue.1 , pp. 432-438
    • Dalip Kumar, N.1    Kumar, M.2    Noel, B.3    Shah, K.4
  • 13
    • 75849164719 scopus 로고    scopus 로고
    • An expeditious synthesis and anticancer activity of novel 4-(3′-indolyl)oxazoles
    • N. Dalip Kumar, M. Kumar, S. Sundaree, O. Emmanuel Johnson, and K. Shah An expeditious synthesis and anticancer activity of novel 4-(3′-indolyl)oxazoles Eur. J. Med. Chem. 45 3 2010 1244 1249
    • (2010) Eur. J. Med. Chem. , vol.45 , Issue.3 , pp. 1244-1249
    • Dalip Kumar, N.1    Kumar, M.2    Sundaree, S.3    Emmanuel Johnson, O.4    Shah, K.5
  • 14
    • 0032814524 scopus 로고    scopus 로고
    • Antifungal properties and target evaluation of three putative bacterial Histidine kinase inhibitors
    • R.J. Deschenes, H. Lin, A.D. Ault, and J.S. Fassler Antifungal properties and target evaluation of three putative bacterial Histidine kinase inhibitors Antimicrob. Agents Chemother. 43 7 1999 1700 1703
    • (1999) Antimicrob. Agents Chemother. , vol.43 , Issue.7 , pp. 1700-1703
    • Deschenes, R.J.1    Lin, H.2    Ault, A.D.3    Fassler, J.S.4
  • 16
    • 33646459158 scopus 로고    scopus 로고
    • Synthesis and antimicrobial activity of new 1-substituted-3-pyrrolyl aminocarbonyl/oxadiazolyl/triazolyl/5-methoxy-2-methylindoles and benz[g]indoles
    • D.S. Donawade, A.V. Raghu, and G.S. Gadaginamath Synthesis and antimicrobial activity of new 1-substituted-3-pyrrolyl aminocarbonyl/oxadiazolyl/triazolyl/5-methoxy-2-methylindoles and benz[g]indoles Indian J. Chem. B 45 3 2006 689 696
    • (2006) Indian J. Chem. B , vol.45 , Issue.3 , pp. 689-696
    • Donawade, D.S.1    Raghu, A.V.2    Gadaginamath, G.S.3
  • 18
    • 0032481002 scopus 로고    scopus 로고
    • Methoxysubstituted 3-formyl-2-phenylindoles inhibit tubulin polymerization
    • R. Gastpeer, M. Goldbrunner, D. Marko, and E.V. Angerer Methoxysubstituted 3-formyl-2-phenylindoles inhibit tubulin polymerization J. Med. Chem. 41 25 1998 4965 4972
    • (1998) J. Med. Chem. , vol.41 , Issue.25 , pp. 4965-4972
    • Gastpeer, R.1    Goldbrunner, M.2    Marko, D.3    Angerer, E.V.4
  • 19
  • 20
    • 31344463744 scopus 로고    scopus 로고
    • Synthesis and antibacterial activity of some substituted 3-(aryl)- and 3-(heteroaryl)indoles
    • Y.M.A. Hiari, A.M. Qaisi, M.M. Abadelah, and W. Voelter Synthesis and antibacterial activity of some substituted 3-(aryl)- and 3-(heteroaryl)indoles Monatshefte Fur Chemie 137 2 2006 243 248
    • (2006) Monatshefte fur Chemie , vol.137 , Issue.2 , pp. 243-248
    • Hiari, Y.M.A.1    Qaisi, A.M.2    Abadelah, M.M.3    Voelter, W.4
  • 21
    • 0345282989 scopus 로고    scopus 로고
    • Discovery of 2-phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors
    • W. Hu, Z. Guo, X. Yi, C. Guo, F. Chu, and G. Cheng Discovery of 2-phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors Bioorg. Med. Chem. 11 24 2003 5539 5544
    • (2003) Bioorg. Med. Chem. , vol.11 , Issue.24 , pp. 5539-5544
    • Hu, W.1    Guo, Z.2    Yi, X.3    Guo, C.4    Chu, F.5    Cheng, G.6
  • 22
    • 34147206298 scopus 로고    scopus 로고
    • Review: Combining pindolol with an SSRI improves early outcomes in people with depression
    • M.T. Isaac Review: combining pindolol with an SSRI improves early outcomes in people with depression Evid. Based Ment. Health 7 4 2004 107 130
    • (2004) Evid. Based Ment. Health , vol.7 , Issue.4 , pp. 107-130
    • Isaac, M.T.1
  • 26
    • 77955673540 scopus 로고    scopus 로고
    • Marine indole alkaloids: Potential new drug leads for the control of depression and anxiety
    • A.J. Kochanowska-Karamyan, and M.T. Hamann Marine indole alkaloids: potential new drug leads for the control of depression and anxiety Chem. Rev. 110 8 2010 4489 4497
    • (2010) Chem. Rev. , vol.110 , Issue.8 , pp. 4489-4497
    • Kochanowska-Karamyan, A.J.1    Hamann, M.T.2
  • 28
    • 79957715003 scopus 로고    scopus 로고
    • Synthesis of pharmacologically active 2-phenyl sulpha/substituted indoles
    • D. Kumar, N. Kumar, S. Kumar, T. Singh, and C.P. Singh Synthesis of pharmacologically active 2-phenyl sulpha/substituted indoles Int. J. Eng. Sci. Tech. 2 7 2010 2553 2557
    • (2010) Int. J. Eng. Sci. Tech. , vol.2 , Issue.7 , pp. 2553-2557
    • Kumar, D.1    Kumar, N.2    Kumar, S.3    Singh, T.4    Singh, C.P.5
  • 29
    • 78049287744 scopus 로고    scopus 로고
    • Synthesis and antiparkinsonian activity of some new adamantyl thiazolidinonyl/azetidinonyl indole derivatives
    • S. Kumar, H. Kaur, K.K. Saxena, M. Sharma, P. Vishwakarma, and A. Kumar Synthesis and antiparkinsonian activity of some new adamantyl thiazolidinonyl/azetidinonyl indole derivatives Indian J. chem. B 49 10 2010 1398 1405
    • (2010) Indian J. Chem. B , vol.49 , Issue.10 , pp. 1398-1405
    • Kumar, S.1    Kaur, H.2    Saxena, K.K.3    Sharma, M.4    Vishwakarma, P.5    Kumar, A.6
  • 31
    • 84870395663 scopus 로고    scopus 로고
    • 2-arylindoles: A privileged molecular scaffold with potent, broad-ranging pharmacological activity
    • S. Lal, and T.J. Snape 2-arylindoles: a privileged molecular scaffold with potent, broad-ranging pharmacological activity Curr. Med. Chem. 19 28 2012 4828 4837
    • (2012) Curr. Med. Chem. , vol.19 , Issue.28 , pp. 4828-4837
    • Lal, S.1    Snape, T.J.2
  • 32
    • 68349135119 scopus 로고    scopus 로고
    • The synthesis of 2- and 3-aryl indoles and 1,3,4,5- tetrahydropyrano[4, 3-b] indoles and their antibacterial and antifungal activity
    • T.C. Leboho, J.P. Michael, W.A.L. Van Otterlo, S.F. Van Vuuren, and C.B. De Koning The synthesis of 2- and 3-aryl indoles and 1,3,4,5- tetrahydropyrano[4, 3-b] indoles and their antibacterial and antifungal activity Bioorg. Med. Chem. Lett. 19 17 2009 4948 4951
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , Issue.17 , pp. 4948-4951
    • Leboho, T.C.1    Michael, J.P.2    Van Otterlo, W.A.L.3    Van Vuuren, S.F.4    De Koning, C.B.5
  • 34
    • 58249083139 scopus 로고    scopus 로고
    • Characteristics of arbidol-resistant mutants of influenza virus: Implications for the mechanism of anti-influenza action of Arbidol
    • I.A. Leneva, R.J. Russell, Y.S. Boriskin, and A.J. Hay Characteristics of arbidol-resistant mutants of influenza virus: implications for the mechanism of anti-influenza action of Arbidol Antivir. Res. 81 2 2009 132 140
    • (2009) Antivir. Res. , vol.81 , Issue.2 , pp. 132-140
    • Leneva, I.A.1    Russell, R.J.2    Boriskin, Y.S.3    Hay, A.J.4
  • 35
    • 34848816197 scopus 로고    scopus 로고
    • The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo
    • Y.Y. Li, H.S. Wu, L. Tang, C.R. Feng, H.Y. Yu, Y.S. Yang, and B.J. Yang The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo Pharmacol. Res. 56 4 2007 335 343
    • (2007) Pharmacol. Res. , vol.56 , Issue.4 , pp. 335-343
    • Li, Y.Y.1    Wu, H.S.2    Tang, L.3    Feng, C.R.4    Yu, H.Y.5    Yang, Y.S.6    Yang, B.J.7
  • 37
    • 84885173028 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′- methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006)
    • M.T. MacDonough, T.E. Strecker, E. Hamel, J.J. Hall, D.J. Chaplin, M.L. Trawick, and K.G. Pinney Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′- methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006) Bioorg. Med. Chem. 21 21 2013 6831 6843
    • (2013) Bioorg. Med. Chem. , vol.21 , Issue.21 , pp. 6831-6843
    • MacDonough, M.T.1    Strecker, T.E.2    Hamel, E.3    Hall, J.J.4    Chaplin, D.J.5    Trawick, M.L.6    Pinney, K.G.7
  • 40
    • 84863885254 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents
    • A. Meric Koksal, Y. Mine Yarim, I. Durmaz, and A. Rengul Cetin Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents Turk. J. Chem. 36 1 2012 515 525
    • (2012) Turk. J. Chem. , vol.36 , Issue.1 , pp. 515-525
    • Meric Koksal, A.1    Mine Yarim, Y.2    Durmaz, I.3    Rengul Cetin, A.4
  • 42
    • 0033984588 scopus 로고    scopus 로고
    • Concentration-targeted phase i trials of Atevirdine mesylate in patients with HIV infection: Dosage requirements and pharmacokinetic studies. The ACTG 187 and 199 study teams
    • G.D. Morse, R.C. Reichman, M.A. Fischl, M. Para, J. Leedom, W. Powderly, L.M. Demeter, L. Resnick, Y. Bassiakos, J. Timpone, S. Cox, and D. Batts Concentration-targeted phase I trials of Atevirdine mesylate in patients with HIV infection: dosage requirements and pharmacokinetic studies. The ACTG 187 and 199 study teams Antivir. Res. 45 1 2000 47 58
    • (2000) Antivir. Res. , vol.45 , Issue.1 , pp. 47-58
    • Morse, G.D.1    Reichman, R.C.2    Fischl, M.A.3    Para, M.4    Leedom, J.5    Powderly, W.6    Demeter, L.M.7    Resnick, L.8    Bassiakos, Y.9    Timpone, J.10    Cox, S.11    Batts, D.12
  • 43
    • 84902380724 scopus 로고    scopus 로고
    • Novel indolyl-pyrimidine derivatives: Synthesis, antimicrobial and antioxidant evaluations
    • M. Mosaad Sayed, Y. Mahmoud Moustafa, and A. Naglaa Mohamed Novel indolyl-pyrimidine derivatives: synthesis, antimicrobial and antioxidant evaluations Med. Chem. Res. 23 7 2014 3374 3388
    • (2014) Med. Chem. Res. , vol.23 , Issue.7 , pp. 3374-3388
    • Mosaad Sayed, M.1    Mahmoud Moustafa, Y.2    Naglaa Mohamed, A.3
  • 45
    • 20544459890 scopus 로고    scopus 로고
    • Synthesis of some new biologically active 1,3,4-oxadiazolyl nitroindoles and a modified Fischer indole synthesis of ethyl nitro indole-2-carboxylates
    • B. Narayana, B.V. Ashalatha, K.K. Vijaya Raj, J. Fernandes, and B.K. Sarojini Synthesis of some new biologically active 1,3,4-oxadiazolyl nitroindoles and a modified Fischer indole synthesis of ethyl nitro indole-2-carboxylates Bioorg. Med. Chem. 13 15 2005 4638 4644
    • (2005) Bioorg. Med. Chem. , vol.13 , Issue.15 , pp. 4638-4644
    • Narayana, B.1    Ashalatha, B.V.2    Vijaya Raj, K.K.3    Fernandes, J.4    Sarojini, B.K.5
  • 46
    • 33845249705 scopus 로고    scopus 로고
    • Yohimbine: The effects on body composition and exercise performance in soccer players
    • S.M. Ostojic Yohimbine: the effects on body composition and exercise performance in soccer players Res. Sports Med. 14 4 2006 289 299
    • (2006) Res. Sports Med. , vol.14 , Issue.4 , pp. 289-299
    • Ostojic, S.M.1
  • 47
    • 1942519876 scopus 로고    scopus 로고
    • Synthesis and anti-inflammatory activity of heterocyclic indole derivatives
    • P. Rani, V.K. Srivastava, and A. Kumar Synthesis and anti-inflammatory activity of heterocyclic indole derivatives Eur. J. Med. Chem. 39 5 2004 449 452
    • (2004) Eur. J. Med. Chem. , vol.39 , Issue.5 , pp. 449-452
    • Rani, P.1    Srivastava, V.K.2    Kumar, A.3
  • 48
    • 69749111046 scopus 로고    scopus 로고
    • Panobinostat (LBH589): A novel pan-deacetylase inhibitor with activity in T cell lymphoma
    • (Parkville, Australia: Peter MacCallum Cancer Centre and University of Melbourne)
    • H.M. Prince, and M. Bishton Panobinostat (LBH589): a novel pan-deacetylase inhibitor with activity in T cell lymphoma Hematology Meeting Reports 3 1 2009 33 38 (Parkville, Australia: Peter MacCallum Cancer Centre and University of Melbourne)
    • (2009) Hematology Meeting Reports , vol.3 , Issue.1 , pp. 33-38
    • Prince, H.M.1    Bishton, M.2
  • 49
    • 43949131415 scopus 로고    scopus 로고
    • Synthesis, (in vitro) antitumor and antimicrobial activity of some pyrazoline, pyridine and pyrimidine derivatives linked to indole moiety
    • M.R.P. Queiroz, A.S. Abreu, M.S.D. Carvalho, P.M.T. Ferreira, N. Nazareth, and M.S. Nascimento Synthesis, (in vitro) antitumor and antimicrobial activity of some pyrazoline, pyridine and pyrimidine derivatives linked to indole moiety Bioorg. Med. Chem. 16 2 2008 5584 5596
    • (2008) Bioorg. Med. Chem. , vol.16 , Issue.2 , pp. 5584-5596
    • Queiroz, M.R.P.1    Abreu, A.S.2    Carvalho, M.S.D.3    Ferreira, P.M.T.4    Nazareth, N.5    Nascimento, M.S.6
  • 50
    • 34247351629 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents
    • M.A.A. Radwan, E.A. Ragab, N.M. Sabrya, and S.M. El-Shenawy Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents Bioorg. Med. Chem. 15 11 2007 3832 3841
    • (2007) Bioorg. Med. Chem. , vol.15 , Issue.11 , pp. 3832-3841
    • Radwan, M.A.A.1    Ragab, E.A.2    Sabrya, N.M.3    El-Shenawy, S.M.4
  • 52
    • 28844448733 scopus 로고    scopus 로고
    • Synthesis of functionalized 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors
    • S. Samosorn, J.B. Bremner, A. Ball, and K. Lewis Synthesis of functionalized 2-aryl-5-nitro-1H-indoles and their activity as bacterial NorA efflux pump inhibitors Bioorg. Med. Chem. 14 3 2006 857 865
    • (2006) Bioorg. Med. Chem. , vol.14 , Issue.3 , pp. 857-865
    • Samosorn, S.1    Bremner, J.B.2    Ball, A.3    Lewis, K.4
  • 53
    • 77953001158 scopus 로고    scopus 로고
    • Biological importance of the indole nucleus in recent years: A comprehensive review
    • V. Sharma, K. Pradeep, and P. Devender Biological importance of the indole nucleus in recent years: a comprehensive review J. Heterocycl. Chem. 47 3 2010 491 502
    • (2010) J. Heterocycl. Chem. , vol.47 , Issue.3 , pp. 491-502
    • Sharma, V.1    Pradeep, K.2    Devender, P.3
  • 54
    • 33750893617 scopus 로고    scopus 로고
    • Synthesis and antimicrobial activity of pyrazolylbisindoles promising antifungal compounds
    • G. Sivaprasad, P.T. Perumal, V.R. Prabavathy, and N. Mathivanan Synthesis and antimicrobial activity of pyrazolylbisindoles promising antifungal compounds Bioorg. Med. Chem. Lett. 16 No. 24 2006 6302 6305
    • (2006) Bioorg. Med. Chem. Lett. , vol.16 , Issue.24 , pp. 6302-6305
    • Sivaprasad, G.1    Perumal, P.T.2    Prabavathy, V.R.3    Mathivanan, N.4
  • 55
    • 78650103335 scopus 로고    scopus 로고
    • Synthesis and anti-inflammatory activity of 3-indolyl pyridine derivatives through one-pot multi component reaction
    • P. Thirumurugan, S. Mahalaxmi, and P.T. Perumal Synthesis and anti-inflammatory activity of 3-indolyl pyridine derivatives through one-pot multi component reaction J. Chem. Sci. 122 6 2010 819 832
    • (2010) J. Chem. Sci. , vol.122 , Issue.6 , pp. 819-832
    • Thirumurugan, P.1    Mahalaxmi, S.2    Perumal, P.T.3
  • 57
    • 18244382316 scopus 로고    scopus 로고
    • Sulfur-nitrogen heterocycles
    • M.G. Valverde, and T. Torroba Sulfur-nitrogen heterocycles Molecules 10 2005 318 320
    • (2005) Molecules , vol.10 , pp. 318-320
    • Valverde, M.G.1    Torroba, T.2
  • 58
    • 77955662196 scopus 로고    scopus 로고
    • 3 mediated one-pot multicomponent synthesis, anti-microbial, antioxidant and anticancer evaluation of 3-pyranyl indole derivatives
    • 3 mediated one-pot multicomponent synthesis, anti-microbial, antioxidant and anticancer evaluation of 3-pyranyl indole derivatives Bioorg. Med. Chem. Lett. 20 17 2010 5054 5061
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , Issue.17 , pp. 5054-5061
    • Vidhya Lakshmi, N.1    Thirumurugan, P.2    Noorulla, K.M.3    Perumal, P.T.4
  • 59
    • 27844463013 scopus 로고    scopus 로고
    • Indole alkaloid marine natural products: An established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases
    • G. Waseem, and M.T. Hamann Indole alkaloid marine natural products: an established source of cancer drug leads with considerable promise for the control of parasitic, neurological and other diseases Life Sci. 78 5 2005 442 453
    • (2005) Life Sci. , vol.78 , Issue.5 , pp. 442-453
    • Waseem, G.1    Hamann, M.T.2
  • 60
    • 48249155730 scopus 로고    scopus 로고
    • Apaziquone for non-muscle invasive bladder cancer: A critical review
    • J.A. Witjes, and P.S. Kolli Apaziquone for non-muscle invasive bladder cancer: a critical review Expert Opin. Investig. Drugs 17 7 2008 1085 1096
    • (2008) Expert Opin. Investig. Drugs , vol.17 , Issue.7 , pp. 1085-1096
    • Witjes, J.A.1    Kolli, P.S.2
  • 62
    • 34548703825 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity of indolopyrrolemaleimides
    • G. Xu, V. Guo, C. Zhang, Q. He, B. Yang, and Y. Hu Synthesis and cytotoxicity of indolopyrrolemaleimides Chem. Pharm. Bull. 55 9 2007 1302 1307
    • (2007) Chem. Pharm. Bull. , vol.55 , Issue.9 , pp. 1302-1307
    • Xu, G.1    Guo, V.2    Zhang, C.3    He, Q.4    Yang, B.5    Hu, Y.6
  • 63
    • 68449083305 scopus 로고    scopus 로고
    • Developments of indoles as anti-HIV-1 inhibitors
    • H. Xu, and M. Lv Developments of indoles as anti-HIV-1 inhibitors Curr. Pharm. Des. 15 18 2009 2120 2148
    • (2009) Curr. Pharm. Des. , vol.15 , Issue.18 , pp. 2120-2148
    • Xu, H.1    Lv, M.2
  • 64
    • 84868018744 scopus 로고    scopus 로고
    • Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFkB inhibitors
    • X. Yu, E.J. Park, T.P. Kondratyuk, J.M. Pezzuto, and D. Sun Synthesis of 2-arylindole derivatives and evaluation as nitric oxide synthase and NFkB inhibitors Org. Biomol. Chem. 10 44 2012 8835 8847
    • (2012) Org. Biomol. Chem. , vol.10 , Issue.44 , pp. 8835-8847
    • Yu, X.1    Park, E.J.2    Kondratyuk, T.P.3    Pezzuto, J.M.4    Sun, D.5
  • 65
    • 79957452750 scopus 로고    scopus 로고
    • Synthesis and antitumor activity of 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives in vitro
    • F. Zhang, Y. Zhao, L. Sun, L. Ding, Y. Gu, and P. Gong Synthesis and antitumor activity of 2-amino-3-cyano-6-(1H-indol-3-yl)-4-phenylpyridine derivatives in vitro Eur. J. Med. Chem. 46 7 2011 3149 3157
    • (2011) Eur. J. Med. Chem. , vol.46 , Issue.7 , pp. 3149-3157
    • Zhang, F.1    Zhao, Y.2    Sun, L.3    Ding, L.4    Gu, Y.5    Gong, P.6
  • 66
    • 84873975114 scopus 로고    scopus 로고
    • Development of n-hydroxycinnamamide-based histone deacetylase inhibitors with an indole-containing cap group
    • Y. Zhang, P. Yang, C.J. Chou, C. Liu, X. Wang, and W. Xu Development of n-hydroxycinnamamide-based histone deacetylase inhibitors with an indole-containing cap group ACS Med. Chem. Lett. 4 2 2013 235 238
    • (2013) ACS Med. Chem. Lett. , vol.4 , Issue.2 , pp. 235-238
    • Zhang, Y.1    Yang, P.2    Chou, C.J.3    Liu, C.4    Wang, X.5    Xu, W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.