Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization

Journal of Medicinal Chemistry

Volumn 41, Issue 25, 1998, Pages 4965-4972

  Gastpar, Robert ^a   Goldbrunner, Michael ^a   Marko, Doris ^b   Von Angerer, Erwin ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b Rheinland Pfälzische Technische Universität Kaiserslautern Landau   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 FORMYL 2 PHENYLINDOLE DERIVATIVE; 3 FORMYL 6 METHOXY 2 (4 METHOXYPHENYL)INDOLE; 3 FORMYLINDOLE; ANTIMITOTIC AGENT; ANTINEOPLASTIC AGENT; COLCHICINE; N [2 [(4 HYDROXYPHENYL)AMINO] 3 PYRIDINYL] 4 METHOXYBENZENESULFONAMIDE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BIOPOLYMERS; BRAIN; BREAST NEOPLASMS; CATTLE; COLCHICINE; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; MICROSCOPY, FLUORESCENCE; NEOPLASMS, HORMONE-DEPENDENT; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUBULIN MODULATORS; TUMOR CELLS, CULTURED;

EID: 0032481002     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm980228l     Document Type: Article

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