SCOPUS 정보 검색 플랫폼

European Journal of Medicinal Chemistry

Volumn 55, Issue , 2012, Pages 432-438

A series of 2-arylamino-5-(indolyl)-1,3,4-thiadiazoles as potent cytotoxic agents

(4) Kumar, Dalip a Kumar, N Maruthi a Noel, Brett b Shah, Kavita b

a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE (India)

b PURDUE UNIVERSITY (United States)

Author keywords

1,3,4 Thiadiazoles; 2 Arylamino 1,3,4 thiadiazoles; Cytotoxic agents; Indolyl heterocycles

Indexed keywords

2 ARYLAMINO 5 (INDOLYL) 1,3,4 THIADIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; DOXORUBICIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; INHIBITORY CONCENTRATION 50; THIADIAZOLES;

EID: 84865770185 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.06.047 Document Type: Article

Times cited : (63)

References (43)

1
- 77953001158
- V. Sharma, P. Kumar, and D. Pathak J. Heterocycl. Chem. 47 2010 491 502
- (2010) J. Heterocycl. Chem. , vol.47 , pp. 491-502
- Sharma, V.¹ Kumar, P.² Pathak, D.³

2
- 84655163502
- A. Kamal, Y.V.V. Srikanth, M.J. Ramaiah, M.N.A. Khan, M. Kashi Reddy, M. Ashraf, A. Lavanya, S.N.C.V.L. Pushpavalli, and M. Pal-Bhadra Bioorg. Med. Chem. Lett. 22 2012 571 578
- (2012) Bioorg. Med. Chem. Lett. , vol.22 , pp. 571-578
- Kamal, A.¹ Srikanth, Y.V.V.² Ramaiah, M.J.³ Khan, M.N.A.⁴ Kashi Reddy, M.⁵ Ashraf, M.⁶ Lavanya, A.⁷ Pushpavalli, S.N.C.V.L.⁸ Pal-Bhadra, M.⁹

3
- 68849110176
- F.R.D.S. Alves, E.J. Barreiro, and C.A.M. Fraga Mini. Rev. Med. Chem. 9 2009 782 793
- (2009) Mini. Rev. Med. Chem. , vol.9 , pp. 782-793
- Alves, F.R.D.S.¹ Barreiro, E.J.² Fraga, C.A.M.³

4
- 33750339847
- J.-P. Liou, N. Mahindroo, C.-W. Chang, F.-M. Guo, S.W.-H. Lee, U.-K. Tan, T.-K. Yeh, C.-C. Kuo, Y.-W. Chang, P.-H. Lu, Y.-S. Tung, K.-T. Lin, J.-Y. Chang, and H.-P. Hsieh ChemMedChem 1 2006 1106 1118
- (2006) ChemMedChem , vol.1 , pp. 1106-1118
- Liou, J.-P.¹ Mahindroo, N.² Chang, C.-W.³ Guo, F.-M.⁴ Lee, S.W.-H.⁵ Tan, U.-K.⁶ Yeh, T.-K.⁷ Kuo, C.-C.⁸ Chang, Y.-W.⁹ Lu, P.-H.¹⁰ Tung, Y.-S.¹¹ Lin, K.-T.¹² Chang, J.-Y.¹³ Hsieh, H.-P.¹⁴

5
- 0036928561
- G.R. Pettit, J.C. Knight, D.L. Herald, R. Davenport, R.K. Pettit, B.E. Tucker, and J.M. Schmidt J. Nat. Prod. 65 2002 1793 1797
- (2002) J. Nat. Prod. , vol.65 , pp. 1793-1797
- Pettit, G.R.¹ Knight, J.C.² Herald, D.L.³ Davenport, R.⁴ Pettit, R.K.⁵ Tucker, B.E.⁶ Schmidt, J.M.⁷

6
- 33845948037
- M.A.A. Radwan, and M. El-Sherbiny Bioorg. Med. Chem. 15 2007 1206 1211
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 1206-1211
- Radwan, M.A.A.¹ El-Sherbiny, M.²

7
- 77956190826
- N.I. Ziedan, F. Stefanelli, S. Fogli, and A.D. Westwell Eur. J. Med. Chem. 45 2010 4523 4530
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 4523-4530
- Ziedan, N.I.¹ Stefanelli, F.² Fogli, S.³ Westwell, A.D.⁴

8
- 67649950035
- D. Kumar, S. Sundaree, E.O. Johnson, and K. Shah Bioorg. Med. Chem. Lett. 19 2009 4492 4494
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 4492-4494
- Kumar, D.¹ Sundaree, S.² Johnson, E.O.³ Shah, K.⁴

9
- 33846581443
- E. Glawischnig Phytochemistry 68 2007 401 406
- (2007) Phytochemistry , vol.68 , pp. 401-406
- Glawischnig, E.¹

10
- 0025809251
- H. Oka, T. Yoshinari, T. Murai, K. Kawamura, F. Satoh, K. Funaishi, A. Okura, H. SUDA, M. Okanishi, and Y. Shizuri J. Antibiot. 44 1991 486 491
- (1991) J. Antibiot. , vol.44 , pp. 486-491
- Oka, H.¹ Yoshinari, T.² Murai, T.³ Kawamura, K.⁴ Satoh, F.⁵ Funaishi, K.⁶ Okura, A.⁷ Suda, H.⁸ Okanishi, M.⁹ Shizuri, Y.¹⁰

11
- 0036510854
- M. Kritsanida, A. Mouroutsou, P. Marakos, N. Pouli, S. Papakonstantinou-Garoufalias, C. Pannecouque, M. Witvrouw, and E. De Clercq Il Farmaco 57 2002 253 257
- (2002) Il Farmaco , vol.57 , pp. 253-257
- Kritsanida, M.¹ Mouroutsou, A.² Marakos, P.³ Pouli, N.⁴ Papakonstantinou- Garoufalias, S.⁵ Pannecouque, C.⁶ Witvrouw, M.⁷ De Clercq, E.⁸

12
- 79957482244
- A.R. Bhat, Tazeem, A. Azam, I. Choi, and F. Athar Eur. J. Med. Chem. 46 2011 3158 3166
- (2011) Eur. J. Med. Chem. , vol.46 , pp. 3158-3166
- Bhat, A.R.¹ Tazeem² Azam, A.³ Choi, I.⁴ Athar, F.⁵

13
- 0036318617
- H.N. Dogan, A. Duran, S. Rollas, G. Sener, M.K. Uysal, and D. Gülen Bioorg. Med. Chem. 10 2002 2893 2898
- (2002) Bioorg. Med. Chem. , vol.10 , pp. 2893-2898
- Dogan, H.N.¹ Duran, A.² Rollas, S.³ Sener, G.⁴ Uysal, M.K.⁵ Gülen, D.⁶

14
- 53549105263
- R. Sharma, J. Sainy, and S.C. Chaturvedi Acta Pharma 58 2008 317 326
- (2008) Acta Pharma , vol.58 , pp. 317-326
- Sharma, R.¹ Sainy, J.² Chaturvedi, S.C.³

15
- 0023909325
- S. Turner, M. Myers, B. Gadie, S.A. Hale, A. Horsley, A.J. Nelson, R. Pape, J.F. Saville, J.C. Doxey, and T.L. Berridge J. Med. Chem. 31 1988 906 913
- (1988) J. Med. Chem. , vol.31 , pp. 906-913
- Turner, S.¹ Myers, M.² Gadie, B.³ Hale, S.A.⁴ Horsley, A.⁵ Nelson, A.J.⁶ Pape, R.⁷ Saville, J.F.⁸ Doxey, J.C.⁹ Berridge, T.L.¹⁰

16
- 11144233944
- E.E. Oruç, S. Rollas, F. Kandemirli, N. Shvets, and A.S. Dimoglo J. Med. Chem. 47 2004 6760 6767
- (2004) J. Med. Chem. , vol.47 , pp. 6760-6767
- Oruç, E.E.¹ Rollas, S.² Kandemirli, F.³ Shvets, N.⁴ Dimoglo, A.S.⁵

17
- 27744523961
- A. Foroumadi, S. Emami, S. Pournourmohammadi, A. Kharazmi, and A. Shafiee Eur. J. Med. Chem. 40 2005 1346 1350
- (2005) Eur. J. Med. Chem. , vol.40 , pp. 1346-1350
- Foroumadi, A.¹ Emami, S.² Pournourmohammadi, S.³ Kharazmi, A.⁴ Shafiee, A.⁵

18
- 0035866653
- F. Clerici, D. Pocar, M. Guido, A. Loche, V. Perlini, and M. Brufani J. Med. Chem. 44 2001 931 936
- (2001) J. Med. Chem. , vol.44 , pp. 931-936
- Clerici, F.¹ Pocar, D.² Guido, M.³ Loche, A.⁴ Perlini, V.⁵ Brufani, M.⁶

19
- 76649118093
- Q. Zeng, M.P. Bourbeau, G.E. Wohlhieter, G. Yao, H. Monenschein, J.T. Rider, M.R. Lee, S. Zhang, J. Lofgren, and D. Freeman Bioorg. Med. Chem. Lett. 20 2010 1652 1656
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 1652-1656
- Zeng, Q.¹ Bourbeau, M.P.² Wohlhieter, G.E.³ Yao, G.⁴ Monenschein, H.⁵ Rider, J.T.⁶ Lee, M.R.⁷ Zhang, S.⁸ Lofgren, J.⁹ Freeman, D.¹⁰

20
- 0037032464
- I.P. Kaur, R. Smitha, D. Aggarwal, and M. Kapil Int. J. Pharm. 248 2002 1 14
- (2002) Int. J. Pharm. , vol.248 , pp. 1-14
- Kaur, I.P.¹ Smitha, R.² Aggarwal, D.³ Kapil, M.⁴

21
- 0023943413
- P.J. Elson, L.K. Kvols, S.E. Vogl, D.J. Glover, R.G. Hahn, D.L. Trump, P.P. Carbone, J.D. Earle, and T.E. Davis Invest. New Drugs 6 1988 97 103
- (1988) Invest. New Drugs , vol.6 , pp. 97-103
- Elson, P.J.¹ Kvols, L.K.² Vogl, S.E.³ Glover, D.J.⁴ Hahn, R.G.⁵ Trump, D.L.⁶ Carbone, P.P.⁷ Earle, J.D.⁸ Davis, T.E.⁹

22
- 0017325190
- J.A. Nelson, L.M. Rose, and L.L. Bennett Cancer Res. 37 1977 182 187
- (1977) Cancer Res. , vol.37 , pp. 182-187
- Nelson, J.A.¹ Rose, L.M.² Bennett, L.L.³

23
- 33947589666
- W. Rzeski, J. Matysiak, and M. Kandefer-Szerszen Bioorg. Med. Chem. 15 2007 3201 3207
- (2007) Bioorg. Med. Chem. , vol.15 , pp. 3201-3207
- Rzeski, W.¹ Matysiak, J.² Kandefer-Szerszen, M.³

24
- 33646559244
- J. Matysiak, and A. Opolski Bioorg. Med. Chem. 14 2006 4483 4489
- (2006) Bioorg. Med. Chem. , vol.14 , pp. 4483-4489
- Matysiak, J.¹ Opolski, A.²

25
- 79851496869
- Y.S. Shan, J. Zhang, Z. Liu, M. Wang, and Y. Dong Curr. Med. Chem. 18 2011 523 538
- (2011) Curr. Med. Chem. , vol.18 , pp. 523-538
- Shan, Y.S.¹ Zhang, J.² Liu, Z.³ Wang, M.⁴ Dong, Y.⁵

26
- 18744379774
- H. Hsieh, J. Liou, and N. Mahindroo Curr. Pharm. Des 11 2005 1655 1677
- (2005) Curr. Pharm. des , vol.11 , pp. 1655-1677
- Hsieh, H.¹ Liou, J.² Mahindroo, N.³

27
- 79954994394
- A. Kamal, J.S. Reddy, M.J. Ramaiah, D. Dastagiri, E.V. Bharathi, M.V. Prem Sagar, S.N.C.V.L. Pushpavalli, P. Ray, and M. Pal-Bhadra MedChemComm 1 2010 355 360
- (2010) MedChemComm , vol.1 , pp. 355-360
- Kamal, A.¹ Reddy, J.S.² Ramaiah, M.J.³ Dastagiri, D.⁴ Bharathi, E.V.⁵ Prem Sagar, M.V.⁶ Pushpavalli, S.N.C.V.L.⁷ Ray, P.⁸ Pal-Bhadra, M.⁹

28
- 79960151500
- Y. Lu, C.-M. Li, Z. Wang, J. Chen, M.L. Mohler, W. Li, J.T. Dalton, and D.D. Miller J. Med. Chem. 54 2011 4678 4693
- (2011) J. Med. Chem. , vol.54 , pp. 4678-4693
- Lu, Y.¹ Li, C.-M.² Wang, Z.³ Chen, J.⁴ Mohler, M.L.⁵ Li, W.⁶ Dalton, J.T.⁷ Miller, D.D.⁸

29
- 46849115345
- C. Peifer, R. Selig, K. Kinkel, D. Ott, F. Totzke, C. Schächtele, R. Heidenreich, M. Röcken, D. Schollmeyer, and S. Laufer J. Med. Chem. 51 2008 3814 3824
- (2008) J. Med. Chem. , vol.51 , pp. 3814-3824
- Peifer, C.¹ Selig, R.² Kinkel, K.³ Ott, D.⁴ Totzke, F.⁵ Schächtele, C.⁶ Heidenreich, R.⁷ Röcken, M.⁸ Schollmeyer, D.⁹ Laufer, S.¹⁰

30
- 51149096446
- L. Lee, R. Davis, J. Vanderham, P. Hills, H. Mackay, T. Brown, S.L. Mooberry, and M. Lee Eur. J. Med. Chem. 43 2008 2011 2015
- (2008) Eur. J. Med. Chem. , vol.43 , pp. 2011-2015
- Lee, L.¹ Davis, R.² Vanderham, J.³ Hills, P.⁴ MacKay, H.⁵ Brown, T.⁶ Mooberry, S.L.⁷ Lee, M.⁸

31
- 10044236627
- G. De Martino, G. La Regina, A. Coluccia, M.C. Edler, M.C. Barbera, A. Brancale, E. Wilcox, E. Hamel, M. Artico, and R. Silvestri J. Med. Chem. 47 2004 6120 6123
- (2004) J. Med. Chem. , vol.47 , pp. 6120-6123
- De Martino, G.¹ La Regina, G.² Coluccia, A.³ Edler, M.C.⁴ Barbera, M.C.⁵ Brancale, A.⁶ Wilcox, E.⁷ Hamel, E.⁸ Artico, M.⁹ Silvestri, R.¹⁰

32
- 79953272674
- D. Kumar, B.R. Vaddula, K.-H. Chang, and K. Shah Bioorg. Med. Chem. Lett. 21 2011 2320 2323
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 2320-2323
- Kumar, D.¹ Vaddula, B.R.² Chang, K.-H.³ Shah, K.⁴

33
- 79651472871
- D. Kumar, N.M. Kumar, K.-H. Chang, and K. Shah Chem. Biol. Drug Des. 77 2011 182 188
- (2011) Chem. Biol. Drug Des. , vol.77 , pp. 182-188
- Kumar, D.¹ Kumar, N.M.² Chang, K.-H.³ Shah, K.⁴

34
- 80052561064
- D. Kumar, N.M. Kumar, K.-H. Chang, R. Gupta, and K. Shah Bioorg. Med. Chem. Lett. 21 2011 5897 5900
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 5897-5900
- Kumar, D.¹ Kumar, N.M.² Chang, K.-H.³ Gupta, R.⁴ Shah, K.⁵

35
- 77956189883
- D. Kumar, N.M. Kumar, K.-H. Chang, and K. Shah Eur. J. Med. Chem. 45 2010 4664 4668
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 4664-4668
- Kumar, D.¹ Kumar, N.M.² Chang, K.-H.³ Shah, K.⁴

36
- 75849164719
- D. Kumar, N.M. Kumar, S. Sundaree, E.O. Johnson, and K. Shah Eur. J. Med. Chem. 45 2010 1244 1249
- (2010) Eur. J. Med. Chem. , vol.45 , pp. 1244-1249
- Kumar, D.¹ Kumar, N.M.² Sundaree, S.³ Johnson, E.O.⁴ Shah, K.⁵

37
- 77954316234
- D. Kumar, N.M. Kumar, K. Akamatsu, E. Kusaka, H. Harada, and T. Ito Bioorg. Med. Chem. Lett. 20 2010 3916 3919
- (2010) Bioorg. Med. Chem. Lett. , vol.20 , pp. 3916-3919
- Kumar, D.¹ Kumar, N.M.² Akamatsu, K.³ Kusaka, E.⁴ Harada, H.⁵ Ito, T.⁶

38
- 22244489351
- M. Lebrini, F. Bentiss, and M. Lagrenée J. Heterocycl. Chem. 42 2005 991 994
- (2005) J. Heterocycl. Chem. , vol.42 , pp. 991-994
- Lebrini, M.¹ Bentiss, F.² Lagrenée, M.³

39
- 19044399556
- R. Severinsen, J.P. Kilburn, and J.F. Lau Tetrahedron 61 2005 5565 5575
- (2005) Tetrahedron , vol.61 , pp. 5565-5575
- Severinsen, R.¹ Kilburn, J.P.² Lau, J.F.³

40
- 62549153106
- V. Padmavathi, G. Sudhakar Reddy, A. Padmaja, P. Kondaiah, and S. Ali Eur. J. Med. Chem. 44 2009 2106 2112
- (2009) Eur. J. Med. Chem. , vol.44 , pp. 2106-2112
- Padmavathi, V.¹ Sudhakar Reddy, G.² Padmaja, A.³ Kondaiah, P.⁴ Ali, S.⁵

41
- 77953001540
- S. Rostamizadeh, R. Aryan, H. Reza Ghaieni, and A. Mohammad Amani J. Heterocycl. Chem. 47 2010 616 623
- (2010) J. Heterocycl. Chem. , vol.47 , pp. 616-623
- Rostamizadeh, S.¹ Aryan, R.² Reza Ghaieni, H.³ Mohammad Amani, A.⁴

42
- 42149114495
- S. Rostamizadeh, R. Aryan, H.R. Ghaieni, and A.M. Amani Heteroatom. Chem. 19 2008 320 324
- (2008) Heteroatom. Chem. , vol.19 , pp. 320-324
- Rostamizadeh, S.¹ Aryan, R.² Ghaieni, H.R.³ Amani, A.M.⁴

43
- 0025924187
- C. Swain, R. Baker, C. Kneen, J. Moseley, J. Saunders, E. Seward, G. Stevenson, M. Beer, J. Stanton, and K. Watling J. Med. Chem. 34 1991 140 151
- (1991) J. Med. Chem. , vol.34 , pp. 140-151
- Swain, C.¹ Baker, R.² Kneen, C.³ Moseley, J.⁴ Saunders, J.⁵ Seward, E.⁶ Stevenson, G.⁷ Beer, M.⁸ Stanton, J.⁹ Watling, K.¹⁰

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.