Evolution-guided functional analyses reveal diverse antiviral specificities encoded by ifit1 genes in mammals

eLife

Volumn 5, Issue MAY2016, 2016, Pages

  Daugherty, Matthew D ^a,b,d   Schaller, Aaron M ^a,e   Geballe, Adam P ^a,c   Malik, Harmit S ^a,b  

^a USA   (United States)

^b HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; FRAMESHIFT MUTATION; GENE; GENE CONVERSION; GENE DUPLICATION; GENE LOCUS; GENE SEQUENCE; HUMAN; IFIT1 GENE; NONHUMAN; NONSENSE MUTATION; PHYLOGENY; PROTEIN EXPRESSION; SEQUENCE ALIGNMENT; TETRATRICOPEPTIDE REPEAT; WESTERN BLOTTING; ANIMAL; BIOASSAY; EVOLUTION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOST PATHOGEN INTERACTION; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE; VACCINIA VIRUS;

CARRIER PROTEIN; IFIT1 PROTEIN, HUMAN; IFIT1 PROTEIN, MOUSE; ISOPROTEIN; MESSENGER RNA; METHYLTRANSFERASE; RNA 2'-O-METHYLTRANSFERASE; VIRAL PROTEIN;

ANIMALS; BIOLOGICAL ASSAY; BIOLOGICAL EVOLUTION; CARRIER PROTEINS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNITY, INNATE; METHYLTRANSFERASES; MICE; PHYLOGENY; PROTEIN ISOFORMS; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SPECIES SPECIFICITY; VACCINIA VIRUS; VIRAL PROTEINS;

EID: 84971655186     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.14228     Document Type: Article

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