Broad and adaptable RNA structure recognition by the human interferon-induced tetratricopeptide repeat protein IFIT5

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 33, 2014, Pages 12025-12030

  Katibah, George E ^a   Qin, Yidan ^b   Sidote, David J ^b   Yao, Jun ^b   Lambowitz, Alan M ^b   Collins, Kathleen ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Innate immunity; Poly U tailing; Protein RNA interaction; RNA post transcriptional modifications; tRNA processing

Indexed keywords

7 METHYLGUANOSINE; HUMAN INTERFERON; MESSENGER RNA; PHOSPHATE; RNA; RNA DIRECTED DNA POLYMERASE; RNA POLYMERASE II; TETRATRICOPEPTIDE REPEAT PROTEIN; TETRATRICOPEPTIDE REPEAT PROTEIN IFIT5; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; INNATE IMMUNITY; INTRON; METHYLATION; MOLECULAR RECOGNITION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; RNA SEQUENCE; RNA STRUCTURE;

INNATE IMMUNITY; POLY-U TAILING; PROTEIN-RNA INTERACTION; RNA POST-TRANSCRIPTIONAL MODIFICATIONS; TRNA PROCESSING;

HUMANS; MODELS, MOLECULAR; NEOPLASM PROTEINS; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; RNA;

EID: 84906308938     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1412842111     Document Type: Article

References (32)

1. Gürtler C, Bowie AG (2013) Innate immune detection of microbial nucleic acids. Trends Microbiol 21(8):413-420.
2. Goubau D, Deddouche S, Reis e Sousa C (2013) Cytosolic sensing of viruses. Immunity 38(5):855-869.
3. Schoggins JW, Rice CM (2011) Interferon-stimulated genes and their antiviral effector functions. Curr Opin Virol 1(6):519-525.
4. Topisirovic I, Svitkin YV, Sonenberg N, Shatkin AJ (2011) Cap and cap-binding proteins in the control of gene expression. Wiley Interdiscip Rev RNA 2(2):277-298.
5. Ghosh A, Lima CD (2010) Enzymology of RNA cap synthesis. Wiley Interdiscip Rev RNA 1(1):152-172.
6. Decroly E, Ferron F, Lescar J, Canard B (2012) Conventional and unconventional mechanisms for capping viral mRNA. Nat Rev Microbiol 10(1):51-65.
7. Daffis S, et al. (2010) 2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members. Nature 468(7322):452-456.
8. Züst R, et al. (2011) Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5. Nat Immunol 12(2):137-143.
9. Szretter KJ, et al. (2012) 2′-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo. PLoS Pathog 8(5):e1002698.
10. Habjan M, et al. (2013) Sequestration by IFIT1 impairs translation of 2'O-unmethylated capped RNA. PLoS Pathog 9(10):e1003663.
11. Kimura T, et al. (2013) Ifit1 inhibits Japanese encephalitis virus replication through binding to 5′ capped 2′-O unmethylated RNA. J Virol 87(18):9997-10003.
12. Zhou X, et al. (2013) Interferon induced IFIT family genes in host antiviral defense. Int J Biol Sci 9(2):200-208.
13. Diamond MS, Farzan M (2013) The broad-spectrum antiviral functions of IFIT and IFITM proteins. Nat Rev Immunol 13(1):46-57.
14. Liu Y, Zhang YB, Liu TK, Gui JF (2013) Lineage-specific expansion of IFIT gene family: An insight into coevolution with IFN gene family. PLoS ONE 8(6):e66859.
15. Pichlmair A, et al. (2011) IFIT1 is an antiviral protein that recognizes 5′-triphosphate RNA. Nat Immunol 12(7):624-630.
16. Katibah GE, et al. (2013) tRNA binding, structure, and localization of the human interferon-induced protein IFIT5. Mol Cell 49(4):743-750.
17. Yang Z, et al. (2012) Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. Cell Res 22(9):1328-1338.
18. Abbas YM, Pichlmair A, Górna MW, Superti-Furga G, Nagar B (2013) Structural basis for viral 5′-PPP-RNA recognition by human IFIT proteins. Nature 494(7435):60-64.
19. Feng F, et al. (2013) Crystal structure and nucleotide selectivity of human IFIT5/ISG58. Cell Res 23(8):1055-1058.
20. Kumar P, et al. (2014) Inhibition of translation by IFIT family members is determined by their ability to interact selectively with the 5′-terminal regions of cap0-, cap1- and 5'ppp- mRNAs. Nucleic Acids Res 42(5):3228-3245.
21. Mohr S, et al. (2013) Thermostable group II intron reverse transcriptase fusion proteins and their use in cDNA synthesis and next-generation RNA sequencing. RNA 19(7):958-970.
22. Collins K, Nilsen TW (2013) Enzyme engineering through evolution: Thermostable recombinant group II intron reverse transcriptases provide new tools for RNA research and biotechnology. RNA 19(8):1017-1018.
23. Phizicky EM, Hopper AK (2010) tRNA biology charges to the front. Genes Dev 24(17):1832-1860.
24. Parrott AM, Mathews MB (2007) Novel rapidly evolving hominid RNAs bind nuclear factor 90 and display tissue-restricted distribution. Nucleic Acids Res 35(18):6249-6258. (Pubitemid 350018586)
25. Parrott AM, et al. (2011) The evolution and expression of the snaR family of small non-coding RNAs. Nucleic Acids Res 39(4):1485-1500.
26. Astuti D, et al. (2012) Germline mutations in DIS3L2 cause the Perlman syndrome of overgrowth and Wilms tumor susceptibility. Nat Genet 44(3):277-284.
27. Chang HM, Triboulet R, Thornton JE, Gregory RI (2013) A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature 497(7448):244-248.
28. Malecki M, et al. (2013) The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway. EMBO J 32(13):1842-1854.
29. Malathi K, Dong B, Gale M, Jr, Silverman RH (2007) Small self-RNA generated by RNase L amplifies antiviral innate immunity. Nature 448(7155):816-819. (Pubitemid 47266340)
30. Li M, et al. (2012) Codon-usage-based inhibition of HIV protein synthesis by human schlafen 11. Nature 491(7422):125-128.
31. Langmead B, Salzberg SL (2012) Fast gapped-read alignment with Bowtie 2. Nat Methods 9(4):357-359.
32. Baker NA, Sept D, Joseph S, Holst MJ, McCammon JA (2001) Electrostatics of nano-systems: Application to microtubules and the ribosome. Proc Natl Acad Sci USA 98(18):10037-10041. (Pubitemid 32802969)