Monoacylglycerol lipase (MGLL) polymorphism rs604300 interacts with childhood adversity to predict cannabis dependence symptoms and amygdala habituation: Evidence from an endocannabinoid system-level analysis

Journal of Abnormal Psychology

Volumn 124, Issue 4, 2015, Pages 860-877

  Carey, Caitlin E ^a   Agrawal, Arpana ^b   Zhang, Bo ^b   Conley, Emily D ^c   Degenhardt, Louisa ^d   Heath, Andrew C ^b   Li, Daofeng ^b   Lynskey, Michael T ^e   Martin, Nicholas G ^f   Montgomery, Grant W ^f   Wang, Ting ^b   Bierut, Laura J ^b   Hariri, Ahmad R ^g   Nelson, Elliot C ^b   Bogdan, Ryan ^a  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of New South Wales ^*  (United States)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

^e KING'S COLLEGE LONDON   (United Kingdom)

^f QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^g DUKE UNIVERSITY   (United States)

Author keywords

Amygdala; Cannabis; Childhood abuse; Endocannabinoid; MGLL

Indexed keywords

2 ARACHIDONOYLGLYCEROL; ACYLGLYCEROL LIPASE; CANNABIS; ENDOCANNABINOID; AMIDASE; CANNABINOID 1 RECEPTOR; CNR1 PROTEIN, HUMAN; DIACYLGLYCEROL LIPASE ALPHA, HUMAN; DIACYLGLYCEROL LIPASE BETA, HUMAN; FATTY-ACID AMIDE HYDROLASE; LIPOPROTEIN LIPASE; NAPEPLD PROTEIN, HUMAN; PHOSPHOLIPASE D;

ADULT; ARTICLE; BASOLATERAL AMYGDALA; BIOSYNTHESIS; CANNABIS ADDICTION; CANNABIS USE; CASE CONTROL STUDY; CATABOLISM; CNR1 GENE; CONTROLLED STUDY; DAGLA GENE; DAGLB GENE; EARLY LIFE STRESS; FAAH GENE; FEMALE; GENE; GENE EXPRESSION; GENE INTERACTION; GENETIC CODE; GENETIC VARIATION; GENOTYPE; HUMAN; MALE; MGLL GENE; NAPEPLD GENE; PATHOGENESIS; PHENOTYPE; SEXUAL ABUSE; SINGLE NUCLEOTIDE POLYMORPHISM; ADOLESCENT; AMYGDALA; CHILD ABUSE SURVIVOR; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; LIFE EVENT; MARIJUANA ABUSE; MIDDLE AGED; PATHOPHYSIOLOGY; PSYCHOLOGY; YOUNG ADULT;

ADOLESCENT; ADULT; ADULT SURVIVORS OF CHILD ABUSE; AMIDOHYDROLASES; AMYGDALA; ENDOCANNABINOIDS; FEMALE; GENE-ENVIRONMENT INTERACTION; GENOTYPE; HUMANS; LIFE CHANGE EVENTS; LIPOPROTEIN LIPASE; MALE; MARIJUANA ABUSE; MIDDLE AGED; MONOACYLGLYCEROL LIPASES; PHOSPHOLIPASE D; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, CANNABINOID, CB1; YOUNG ADULT;

EID: 84971464626     PISSN: 0021843X     EISSN: 19391846     Source Type: Journal    
DOI: 10.1037/abn0000079     Document Type: Article

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