Gene × environment interaction studies have not properly controlled for potential confounders: The problem and the (simple) solution

Biological Psychiatry

Volumn 75, Issue 1, 2014, Pages 18-24

  Keller, Matthew C ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Adjustment; confounders; covariates; false positive rate; gene environment interactions; gene by environment interactions; multiple regression; replication

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMPHETAMINE; CANNABIS; CATECHOL METHYLTRANSFERASE; PSYCHEDELIC AGENT;

CANNABIS SMOKING; CONDUCT DISORDER; CONFOUNDING VARIABLE; DEPRESSION; ETHNICITY; FALSE POSITIVE RESULT; GENE FREQUENCY; GENE INTERACTION; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; PRIORITY JOURNAL; PSYCHOSIS; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIAL STATUS; SOCIAL SUPPORT;

ADJUSTMENT; CONFOUNDERS; COVARIATES; FALSE POSITIVE RATE; GENE × ENVIRONMENT INTERACTIONS; GENE-BY-ENVIRONMENT INTERACTIONS; MULTIPLE REGRESSION; REPLICATION;

CONFOUNDING FACTORS (EPIDEMIOLOGY); GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MENTAL DISORDERS;

EID: 84889584152     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.09.006     Document Type: Review

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