Altered affective response in marijuana smokers: An FMRI study

Drug and Alcohol Dependence

Volumn 105, Issue 1-2, 2009, Pages 139-153

  Gruber, Staci A ^a,b   Rogowska, Jadwiga ^a,b   Yurgelun Todd, Deborah A ^c  

^a MCLEAN HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

Amygdala; Cingulate; fMRI; Marijuana; Masked affect

Indexed keywords

CANNABINOID 1 RECEPTOR;

ADULT; AMYGDALOID NUCLEUS; ARTICLE; BRAIN DEPTH STIMULATION; CANNABIS ADDICTION; CINGULATE GYRUS; CLINICAL ARTICLE; CONSCIOUSNESS; CONTROLLED STUDY; EMOTIONALITY; FEAR; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HAPPINESS; HUMAN; LIMBIC SYSTEM; MALE; MOOD DISORDER; PRIORITY JOURNAL; SENSORY STIMULATION; SMOKING HABIT;

ADULT; AFFECT; AMYGDALA; BRAIN; DEPRESSION; FEMALE; FUNCTIONAL LATERALITY; GYRUS CINGULI; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MARIJUANA ABUSE; MARIJUANA SMOKING; NEURAL PATHWAYS; OXYGEN; PREFRONTAL CORTEX;

CANNABIS SATIVA;

EID: 69949102776     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2009.06.019     Document Type: Article

References (62)

1. Alves C.N., Goyos A.C., and Carlin E.A. Aggressiveness induced by marijuana and other psychotropic drugs in REM sleep-deprived rats. Pharmacol. Biochem. Behav. 1 (1973) 183-189
2. Bac P., Pages N., Herrenknecht C., and Paris M. Measurement of the three phases of muricidal behavior induced by delta9-tetrahydrocannabinol in isolated, fasting rats. Physiol. Behav. 63 (1998) 815-820
3. Beck A. Beck Depression Inventory (1987), The Psychological Corporation, San Antonio, TX
4. Budney A.J., Hughes J.R., Moore B.A., and Novy P.L. Marijuana abstinence effects in marijuana smokers maintained in their home environment. Arch. Gen. Psychiatry 58 (2001) 917-924
5. Budney A.J., Moore B.A., Vandrey R.A., and Hughes J.R. Onset, magnitude and duration of abstinene effects following heavy marijuana use. Drug Alcohol Depend. 66 (2002) S23
6. Budney A.J., Hughes J.R., Moore B.A., and Vandry R. Review of the validity and significance of the cannabis withdrawal syndrome. Am. J. Psychaitry 11 (2004) 1967-1977
7. Chait L.D., Corwin R.L., and Johanson C.E. A cumulative dosing procedure for administering marijuana smoke to humans. Pharmacol. Biochem. Behav. 29 (1988) 553-557
8. Chait L.D., Fischman M.W., and Schuster C.R. 'Hangover' effects the morning after marijuana smoking. Drug Alcohol Depend. 15 (1985) 229-238
9. Chaperon F., and Thiebot M.H. Behavioral effects of cannabinoid agents in animals. Crit. Rev. Neurobiol. 13 (1999) 243-281
10. Cherek D.R., Thompson T., and Kelly T. Chronic delta 9-tetrahydrocannabinol administration and schedule-induced aggression. Pharmacol. Biochem. Behav. 12 (1980) 305-309
11. Clopton P.L., Janowsky D.S., Clopton J.M., Judd L.L., and Huey L. Marijuana and the perception of affect. Psychopharmacology (Berl.) 61 (1979) 203-206
12. Devinsky O., Morrell M.J., and Vogt B.A. Contributions of anterior cingulate cortex to behaviour. Brain 118 Part 1 (1995) 279-306
13. Eldreth D.A., Matochik J.A., Cadet J.L., and Bolla K.I. Abnormal brain activity in prefrontal brain regions in abstinent marijuana users. Neuroimage 23 (2004) 914-920
14. First M., Spitzer R., Gibbon M., and Williams J. Structured Clinical Interview for DSM-IV-Axis Disorders - Patient Edition (SCID-I/P, Version 2.0) (1995), New York State Psychiatric Institute, New York
15. Friston K.J., Frith C.D., Frackowiak R.S., and Turner R. Characterizing dynamic brain responses with fMRI: A multivariate approach. Neuroimage 2 2 (1995) 166-172
16. Friston K.J., Frith C.D., Turner R., and Frackowiak R.S. Characterizing evoked hemodynamics with fMRI. Neuroimage 2 2 (1995) 157-165
17. Galanter M., Stillman R., Wyatt R.J., Vaughan T.B., Weingartner H., and Nurnberg F.L. Marihuana and social behavior; a controlled study. Arch. Gen. Psychiatry 30 (1974) 518-521
18. Gobbi G., Bambico F.R., Mangieri R., Bortolato M., Campolongo P., Solinas M., Cassano T., Morgese M.G., Debonnel G., Duranti A., Tontini A., Tarzia G., Mor M., Trezza V., Goldberg S.R., Cuomo V., and Piomelli D. Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 18620-18625
19. Green B., Kavanagh D., and Young R. Being stoned: a review of self-reported cannabis effects. Drug Alcohol Rev. 22 (2003) 453-460
20. Gruber S.A., and Yurgelun-Todd D.A. Neuroimaging of marijuana smokers during inhibitory processing: a pilot investigation. Brain Res. Cogn. Brain Res. 23 (2005) 107-118
21. Haney M., Ward A.S., Comer S.D., Foltin R.W., and Fischman M.W. Abstinence symptoms following oral THC administration to humans. Psychopharmacology (Berl.) 141 (1999) 385-394
22. Haney M., Ward A.S., Comer S.D., Foltin R.W., and Fischman M.W. Abstinence symptoms following smoked marijuana in humans. Psychopharmacology (Berl.) 141 (1999) 395-404
23. Hariri A.R., Mattay V.S., Tessitore A., Fera F., Smith W.G., and Weinberger D.R. Dextroamphetamine modulates the response of the human amygdala. Neuropsychopharmacology 27 (2002) 1036-1040
24. Hart C.L., Ward A.S., Haney M., Comer S.D., Foltin R.W., and Fischman M.W. Comparison of smoked marijuana and oral Delta(9)-tetrahydrocannabinol in humans. Psychopharmacology (Berl.) 164 (2002) 407-415
25. Herkenham M., Lynn A., Little M., Johnson M., Melvin L., DeCosta B., and Rice K. Cannabinoid receptor localization in brain. Proc. Natl. Acad. Sci. U.S.A. 87 (1990) 1932-1936
26. Hill M.N., Sun J.C., Tse M.T., and Gorzalka B.B. Altered responsiveness of serotonin receptor subtypes following long-term cannabinoid treatment. Int. J. Neuropsychopharmacol. 9 (2006) 277-286
27. Hollister L.E. Health aspects of cannabis. Pharmacol. Rev. 38 (1986) 1-20
28. Hungund B.L., Vinod K.Y., Kassir S.A., Basavarajappa B.S., Yalamanchili R., Cooper T.B., Mann J.J., and Arango V. Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims. Mol. Psychiatry 9 (2004) 184-190
29. Janowsky D.S., Clopton P.L., Leichner P.P., Abrams A.A., Judd L.L., and Pechnick R. Interpersonal effects of marijuana. A model for the study of interpersonal psychopharmacology. Arch. Gen. Psychiatry 36 (1979) 781-785
30. Johnston L.D., O'Malley P.M., Bachman J.G., and Schulenberg J.E. Monitoring the Future National Results on Adolescent Drug Use: Overview of Key Findings, 2004 (2005), National Institutes of Health, Rockville, MD p. 72
31. Joseph R. Neuropsychiatry, Neuropsychology, Clinical Neuroscience (1996), Williams & Wilkins, Baltimore, MD
32. Katona I., Rancz E.A., Acsady L., Ledent C., Mackie K., Hajos N., and Freund T.F. Distribution of CB1 cannabinoid receptors in the amygdala and their role in the control of GABAergic transmission. J. Neurosci. 21 (2001) 9506-9518
33. Killgore W.D., and Yurgelun-Todd D.A. Activation of the amygdala and anterior cingulate during nonconscious processing of sad versus happy faces. Neuroimage 21 (2004) 1215-1223
34. Kouri E.M., and Pope H.G. Abstinence symptoms during withdrawal from chronic marijuana use. Exp. Clin. Psychopharmacol. 4 (2000) 483-492
35. Laviolette S.R., and Grace A.A. Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs. J. Neurosci. 26 (2006) 6458-6468
36. Limonero J.T., Tomas-Sabado J., and Fernandez-Castro J. Perceived emotional intelligence and its relation to tobacco and cannabis use among university students. Psicothema 18 Suppl. (2006) 95-100
37. Maldjian J.A., Laurienti P.J., and Burdette J.H. Precentral gyrus discrepancy in electronic versions of the Talairach atlas. Neuroimage 21 1 (2004) 450-455
38. Maldjian J.A., Laurienti P.J., Kraft R.A., and Burdette J.H. An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage 19 3 (2003) 1233-1239
39. Martin C.A., Kelly T.H., Rayens M.K., Brogli B.R., Brenzel A., Smith W.J., and Omar H.A. Sensation seeking, puberty, and nicotine, alcohol, and marijuana use in adolescence. J. Am. Acad. Child Adolesc. Psychiatry 41 (2002) 1495-1502
40. Mathew R.J., Wilson W.H., Turkington T.G., and Coleman R.E. Cerebellar activity and disturbed time sense after THC. Brain Res. 797 (1998) 183-189
41. Mathew R.J., Wilson W.H., Turkington T.G., Hawk T.C., Coleman R.E., DeGrado T.R., and Provenzale J. Time course of tetrahydrocannabinol-induced changes in regional cerebral blood flow measured with positron emission tomography. Psychiatry Res. 116 (2002) 173-185
42. McDonald J., Schleifer L., Richards J.B., and de Wit H. Effects of THC on behavioral measures of impulsivity in humans. Neuropsychopharmacology 28 (2003) 1356-1365
43. McNair D., Lorr M., and Droppleman L. Manual for the Profile of Mood States (1971), Educational & Industrial Testing Services, San Diego
44. Morris J.S., Ohman A., and Dolan R.J. A subcortical pathway to the right amygdala mediating "unseen" fear. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 1680-1685
45. Nahas G. General toxicity of cannabis. In: Nahas G., and Latour C. (Eds). Cannabis: Physiopathology, Epidemiology, Detection (1993), CRC Press, Boca Raton, FL 5-17
46. O'Leary D.S., Block R.I., Flaum M., Schultz S.K., Boles Ponto L.L., Watkins G.L., Hurtig R.R., Andreasen N.C., and Hichwa R.D. Acute marijuana effects on rCBF and cognition: a PET study. Neuroreport 11 (2000) 3835-3841
47. O'Leary D.S., Block R.I., Koeppel J.A., Flaum M., Schultz S.K., Andreasen N.C., Ponto L.B., Watkins G.L., Hurtig R.R., and Hichwa R.D. Effects of smoking marijuana on brain perfusion and cognition. Neuropsychopharmacology 26 (2002) 802-816
48. Patel S., Cravatt B.F., and Hillard C.J. Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology 30 (2005) 497-507
49. Paulus M.P., Feinstein J.S., Castillo G., Simmons A.N., and Stein M.B. Dose-dependent decrease of activation in bilateral amygdala and insula by lorazepam during emotion processing. Arch. Gen. Psychiatry 62 (2005) 282-288
50. Pertwee R.G. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol. Ther. 74 (1997) 129-180
51. Phan K.L., Angstadt M., Golden J., Onyewuenyi I., Popovska A., and de Wit H. Cannabinoid modulation of amygdala reactivity to social signals of threat in humans. J. Neurosci. 28 (2008) 2313-2319
52. Rodriguez de Fonseca F., Rubio P., Menzaghi F., Merlo-Pich E., Rivier J., Koob G.F., and Navarro M. Corticotropin-releasing factor (CRF) antagonist [D-Phe12,Nle21,38,C alpha MeLeu37]CRF attenuates the acute actions of the highly potent cannabinoid receptor agonist HU-210 on defensive-withdrawal behavior in rats. J. Pharmacol. Exp. Ther. 276 (1996) 56-64
53. Sheline Y.I., Barch D.M., Donnelly J.M., Ollinger J.M., Snyder A.Z., and Mintun M.A. Increased amygdala response to masked emotional faces in depressed subjects resolves with antidepressant treatment: an fMRI study. Biol. Psychiatry 50 (2001) 651-658
54. Tart C.T. On Being Stoned: A Psychological Study of Marijuana Intoxication (1971), Science and Behavior Books, Palo Alto, CA
55. Tinklenberg J., and Darley C. A Model of Marihuana's Cognitive Effects (1976), Raven Press, New York
56. Vinod K.Y., Arango V., Xie S., Kassir S.A., Mann J.J., Cooper T.B., and Hungund B.L. Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide victims. Biol. Psychiatry 57 (2005) 480-486
57. Wachtel S.R., ElSohly M.A., Ross S.A., Ambre J., and de Wit H. Comparison of the subjective effects of Delta(9)-tetrahydrocannabinol and marijuana in humans. Psychopharmacology (Berl.) 161 (2002) 331-339
58. Wadsworth E.J., Moss S.C., Simpson S.A., and Smith A.P. Cannabis use, cognitive performance and mood in a sample of workers. J. Psychopharmacol. 20 (2006) 14-23
59. Watson D., Clark L.A., and Tellegen A. Development and validation of brief measures of positive and negative affect: the PANAS scales. J. Pers. Soc. Psychol. 54 (1988) 1063-1070
60. Whalen P.J., Rauch S.L., Etcoff N.L., McInerney S.C., Lee M.B., and Jenike M.A. Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. J. Neurosci. 18 (1998) 411-418
61. Witkin J.M., Tzavara E.T., and Nomikos G.G. A role for cannabinoid CB1 receptors in mood and anxiety disorders. Behav. Pharmacol. 16 (2005) 315-331
62. Zavitsanou K., Garrick T., and Huang X.F. Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 28 (2004) 355-360