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Volumn 13, Issue 6, 2016, Pages 4969-4980

Identification of TLR2 and TLR4-induced microRNAs in human mesenchymal stem cells and their possible roles in regulating TLR signals

Author keywords

Human; Mesenchymal stem cells; MicroRNAs; Toll like receptors

Indexed keywords

LIPOPOLYSACCHARIDE; MICRORNA; MICRORNA 1; MICRORNA 125A 5P; MICRORNA 137; MICRORNA 154 3P; MICRORNA 15A 5P; MICRORNA 181A 5P; MICRORNA 181C 3P; MICRORNA 186 5P; MICRORNA 199A 3P; MICRORNA 199B 3P; MICRORNA 221 3P; MICRORNA 222 3P; MICRORNA 24 3P; MICRORNA 29A 3P; MICRORNA 30D 5P; MICRORNA 30E 5P; MICRORNA 323A 3P; MICRORNA 323B 3P; MICRORNA 335 5P; MICRORNA 337 3P; MICRORNA 361 5P; MITOGEN ACTIVATED PROTEIN KINASE; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; LIPOPEPTIDE; MESSENGER RNA; PAM(3)CSK(4) PEPTIDE;

EID: 84966470238     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2016.5197     Document Type: Article
Times cited : (17)

References (62)
  • 1
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • Yates LA, Norbury CJ and Gilbert RJ: The long and short of microRNA. Cell 153: 516-519, 2013.
    • (2013) Cell , vol.153 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 2
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP: MicroRNAs: Target recognition and regulatory functions. Cell 136: 215-233, 2009.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 3
    • 77953629046 scopus 로고    scopus 로고
    • Regulation of mRNA translation and stability by microRNAs
    • Fabian MR, Sonenberg N and Filipowicz W: Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79: 351-379, 2010.
    • (2010) Annu Rev Biochem , vol.79 , pp. 351-379
    • Fabian, M.R.1    Sonenberg, N.2    Filipowicz, W.3
  • 6
    • 77957845081 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells: Historical overview and concepts
    • Charbord P: Bone marrow mesenchymal stem cells: Historical overview and concepts. Hum Gene Ther 21: 1045-1056, 2010.
    • (2010) Hum Gene Ther , vol.21 , pp. 1045-1056
    • Charbord, P.1
  • 7
    • 28444490061 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Lineage, plasticity and skeletal therapeutic potential
    • Oreffo RO, Cooper C, Mason C and Clements M: Mesenchymal stem cells: Lineage, plasticity and skeletal therapeutic potential. Stem Cell Rev 1: 169-178, 2005.
    • (2005) Stem Cell Rev , vol.1 , pp. 169-178
    • Oreffo, R.O.1    Cooper, C.2    Mason, C.3    Clements, M.4
  • 8
    • 33845995756 scopus 로고    scopus 로고
    • Role of toll-like receptors on human adipose-derived stromal cells
    • Hwa Cho H, Bae YC and Jung JS: Role of toll-like receptors on human adipose-derived stromal cells. Stem Cells 24: 2744-2752, 2006.
    • (2006) Stem Cells , vol.24 , pp. 2744-2752
    • Hwa, C.H.1    Bae, Y.C.2    Jung, J.S.3
  • 10
    • 84855834035 scopus 로고    scopus 로고
    • Toll-like receptors 2 and 4 mediate the capacity of mesenchymal stromal cells to support the proliferation and differentiation of CD34+cells
    • Wang X, Cheng Q, Li L, Wang J, Xia L, Xu X and Sun Z: Toll-like receptors 2 and 4 mediate the capacity of mesenchymal stromal cells to support the proliferation and differentiation of CD34+cells. Exp Cell Re 318: 196-206, 2012.
    • (2012) Exp Cell Re , vol.318 , pp. 196-206
    • Wang, X.1    Cheng, Q.2    Li, L.3    Wang, J.4    Xia, L.5    Xu, X.6    Sun, Z.7
  • 12
    • 84876940514 scopus 로고    scopus 로고
    • MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling
    • Quinn EM, Wang JH, O'Callaghan G and Redmond HP: MicroRNA-146a is upregulated by and negatively regulates TLR2 signaling. PLoS One 8: e62232, 2013.
    • (2013) PLoS One , vol.8 , pp. e62232
    • Quinn, E.M.1    Wang, J.H.2    O'Callaghan, G.3    Redmond, H.P.4
  • 13
    • 73649145490 scopus 로고    scopus 로고
    • NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection
    • O'Hara SP, Splinter PL, Gajdos GB, Trussoni CE, Fernandez-Zapico ME, Chen XM and LaRusso NF: NFkappaB p50-CCAAT/enhancer-binding protein beta (C/EBPbeta)-mediated transcriptional repression of microRNA let-7i following microbial infection. J Biol Chem 285: 216-225, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 216-225
    • O'Hara, S.P.1    Splinter, P.L.2    Gajdos, G.B.3    Trussoni, C.E.4    Fernandez-Zapico, M.E.5    Chen, X.M.6    LaRusso, N.F.7
  • 14
    • 79952575527 scopus 로고    scopus 로고
    • MIR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4
    • Yang K, He YS, Wang XQ, Lu L, Chen QJ, Liu J, Sun Z and Shen WF: MIR-146a inhibits oxidized low-density lipoprotein-induced lipid accumulation and inflammatory response via targeting toll-like receptor 4. FEBS Lett 585: 854-860, 2011.
    • (2011) FEBS Lett , vol.585 , pp. 854-860
    • Yang, K.1    He, Y.S.2    Wang, X.Q.3    Lu, L.4    Chen, Q.J.5    Liu, J.6    Sun, Z.7    Shen, W.F.8
  • 15
    • 38049030287 scopus 로고    scopus 로고
    • Modulation of MIR-155 and MIR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
    • Tili E, Michaille JJ, Cimino A, Costinean S, Dumitru CD, Adair B, Fabbri M, Alder H, Liu CG, Calin GA and Croce CM: Modulation of MIR-155 and MIR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 179: 5082-5089, 2007.
    • (2007) J Immunol , vol.179 , pp. 5082-5089
    • Tili, E.1    Michaille, J.J.2    Cimino, A.3    Costinean, S.4    Dumitru, C.D.5    Adair, B.6    Fabbri, M.7    Alder, H.8    Liu, C.G.9    Calin, G.A.10    Croce, C.M.11
  • 18
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408, 2001.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 19
    • 33845995756 scopus 로고    scopus 로고
    • Role of toll-like receptors on human adipose-derived cells
    • Hwa Cho H, Bae YC and Jung JS: Role of toll-like receptors on human adipose-derived cells. Stem Cells 24: 2744-2752, 2006.
    • (2006) Stem Cells , vol.24 , pp. 2744-2752
    • Hwa, C.H.1    Bae, Y.C.2    Jung, J.S.3
  • 21
    • 38349060182 scopus 로고    scopus 로고
    • Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T cell modulatory activity by 634 impairing Notch signaling
    • Liotta F, Angeli R, Cosmi L, Filì L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, et al: Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T cell modulatory activity by 634 impairing Notch signaling. Stem Cells 26: 279-289, 2008.
    • (2008) Stem Cells , vol.26 , pp. 279-289
    • Liotta, F.1    Angeli, R.2    Cosmi, L.3    Filì, L.4    Manuelli, C.5    Frosali, F.6    Mazzinghi, B.7    Maggi, L.8    Pasini, A.9    Lisi, V.10
  • 22
    • 65649089411 scopus 로고    scopus 로고
    • Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R
    • Opitz CA, Litzenburger UM, Lutz C, Lanz TV, Tritschler I, Köppel A, Tolosa E, Hoberg M, Anderl J, Aicher WK, et al: Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells 27: 909-919, 2009.
    • (2009) Stem Cells , vol.27 , pp. 909-919
    • Opitz, C.A.1    Litzenburger, U.M.2    Lutz, C.3    Lanz, T.V.4    Tritschler, I.5    Köppel, A.6    Tolosa, E.7    Hoberg, M.8    Anderl, J.9    Aicher, W.K.10
  • 23
  • 24
    • 67649209791 scopus 로고    scopus 로고
    • Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype
    • Romieu-Mourez R, François M, Boivin MN, Bouchentouf M, Spaner DE and Galipeau J: Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol 182: 7963-7973, 2009.
    • (2009) J Immunol , vol.182 , pp. 7963-7973
    • Romieu-Mourez, R.1    François, M.2    Boivin, M.N.3    Bouchentouf, M.4    Spaner, D.E.5    Galipeau, J.6
  • 25
    • 80051551689 scopus 로고    scopus 로고
    • MiRNA profiling for clear cell renal cell carcinoma: Biomarker discovery and identification of potential controls and consequences of miRNA dysregulation
    • White NM, Bao TT, Grigull J, Youssef YM, Girgis A, Diamandis M, Fatoohi E, Metias M, Honey RJ, Stewart R, et al: miRNA profiling for clear cell renal cell carcinoma: Biomarker discovery and identification of potential controls and consequences of miRNA dysregulation. J Urol 186: 1077-1083, 2011.
    • (2011) J Urol , vol.186 , pp. 1077-1083
    • White, N.M.1    Bao, T.T.2    Grigull, J.3    Youssef, Y.M.4    Girgis, A.5    Diamandis, M.6    Fatoohi, E.7    Metias, M.8    Honey, R.J.9    Stewart, R.10
  • 26
    • 84896701866 scopus 로고    scopus 로고
    • NF-kappaB-dependent MicroRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction
    • Ma J, Liu J, Wang Z, Gu X, Fan Y, Zhang W, Xu L, Zhang J and Cai D: NF-kappaB-dependent MicroRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction. Mol Cancer 13: 40, 2014.
    • (2014) Mol Cancer , vol.13 , pp. 40
    • Ma, J.1    Liu, J.2    Wang, Z.3    Gu, X.4    Fan, Y.5    Zhang, W.6    Xu, L.7    Zhang, J.8    Cai, D.9
  • 27
    • 84862562593 scopus 로고    scopus 로고
    • MicroRNAs MIR-96, MIR-124 and MIR-199a regulate gene expression in human bone marrow-derived mesenchymal stem cells
    • Laine SK, Alm JJ, Virtanen SP, Aro HT and Laitala-Leinonen TK: MicroRNAs MIR-96, MIR-124 and MIR-199a regulate gene expression in human bone marrow-derived mesenchymal stem cells. J Cell Biochem 113: 2687-2695, 2012.
    • (2012) J Cell Biochem , vol.113 , pp. 2687-2695
    • Laine, S.K.1    Alm, J.J.2    Virtanen, S.P.3    Aro, H.T.4    Laitala-Leinonen, T.K.5
  • 28
    • 84898956531 scopus 로고    scopus 로고
    • In vitro screening of LPS-induced miRNAs in leukocytes derived from cord blood and their possible roles in regulating TLR signals
    • Chen J, Liu Z and Yang Y: In vitro screening of LPS-induced miRNAs in leukocytes derived from cord blood and their possible roles in regulating TLR signals. Pediatr Res 75: 595-602, 2014.
    • (2014) Pediatr Res , vol.75 , pp. 595-602
    • Chen, J.1    Liu, Z.2    Yang, Y.3
  • 29
    • 46549083928 scopus 로고    scopus 로고
    • Control of chondrogenesis by the transcription factor Sox9
    • Akiyama H: Control of chondrogenesis by the transcription factor Sox9. Mod Rheumatol 18: 213-219, 2008.
    • (2008) Mod Rheumatol , vol.18 , pp. 213-219
    • Akiyama, H.1
  • 30
    • 66449127376 scopus 로고    scopus 로고
    • MIR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1
    • Lin EA, Kong L, Bai XH, Luan Y and Liu CJ: MIR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1. J Biol Chem 284: 11326-11335, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 11326-11335
    • Lin, E.A.1    Kong, L.2    Bai, X.H.3    Luan, Y.4    Liu, C.J.5
  • 31
    • 84899144021 scopus 로고    scopus 로고
    • Keloid microRNA expression analysis and the influence of MIR-199a-5p on the proliferation of keloid fibroblasts
    • Wu ZY, Lu L, Liang J, Guo XR, Zhang PH and Luo SJ: Keloid microRNA expression analysis and the influence of MIR-199a-5p on the proliferation of keloid fibroblasts. Genet Mol Res 13: 2727-2738, 2014.
    • (2014) Genet Mol Res , vol.13 , pp. 2727-2738
    • Wu, Z.Y.1    Lu, L.2    Liang, J.3    Guo, X.R.4    Zhang, P.H.5    Luo, S.J.6
  • 34
    • 79960105300 scopus 로고    scopus 로고
    • Inhibition of MIR-214 expression represses proliferation and differentiation of C2C12 myoblasts
    • Feng Y, Cao JH, Li XY and Zhao SH: Inhibition of MIR-214 expression represses proliferation and differentiation of C2C12 myoblasts. Cell Biochem Funct 29: 378-383, 2011.
    • (2011) Cell Biochem Funct , vol.29 , pp. 378-383
    • Feng, Y.1    Cao, J.H.2    Li, X.Y.3    Zhao, S.H.4
  • 35
    • 84879826452 scopus 로고    scopus 로고
    • MIR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN
    • Yang TS, Yang XH, Wang XD, Wang YL, Zhou B and Song ZS: MIR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN. Cancer Cell Int 13: 68, 2013.
    • (2013) Cancer Cell Int , vol.13 , pp. 68
    • Yang, T.S.1    Yang, X.H.2    Wang, X.D.3    Wang, Y.L.4    Zhou, B.5    Song, Z.S.6
  • 36
    • 84902686206 scopus 로고    scopus 로고
    • Knockdown of MIR-214 promotes apoptosis and inhibits cell proliferation in nasopharyngeal carcinoma
    • Zhang ZC, Li YY, Wang HY, Fu S, Wang XP, Zeng MS, Zeng YX and Shao JY: Knockdown of MIR-214 promotes apoptosis and inhibits cell proliferation in nasopharyngeal carcinoma. PLoS One 9: e86149, 2014.
    • (2014) PLoS One , vol.9 , pp. e86149
    • Zhang, Z.C.1    Li, Y.Y.2    Wang, H.Y.3    Fu, S.4    Wang, X.P.5    Zeng, M.S.6    Zeng, Y.X.7    Shao, J.Y.8
  • 37
    • 80755144048 scopus 로고    scopus 로고
    • Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase
    • Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T and Sartorelli V: Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis 32: 1607-1614, 2011.
    • (2011) Carcinogenesis , vol.32 , pp. 1607-1614
    • Derfoul, A.1    Juan, A.H.2    Difilippantonio, M.J.3    Palanisamy, N.4    Ried, T.5    Sartorelli, V.6
  • 38
    • 79955015683 scopus 로고    scopus 로고
    • A minireview: The role of MAPK/ERK and PI3K/Akt pathways in thyroid follicular cell-derived neoplasm
    • Brzezianska E and Pastuszak-Lewandoska D: A minireview: The role of MAPK/ERK and PI3K/Akt pathways in thyroid follicular cell-derived neoplasm. Front Biosci (Landmark Ed) 16: 422-439, 2011.
    • (2011) Front Biosci (Landmark Ed) , vol.16 , pp. 422-439
    • Brzezianska, E.1    Pastuszak-Lewandoska, D.2
  • 39
    • 84872722692 scopus 로고    scopus 로고
    • Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by MIR-132 and MIR-212
    • Nahid MA, Yao B, Dominguez-Gutierrez PR, Kesavalu L, Satoh M and Chan EK: Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by MIR-132 and MIR-212. J Immunol 190: 1250-1263, 2013.
    • (2013) J Immunol , vol.190 , pp. 1250-1263
    • Nahid, M.A.1    Yao, B.2    Dominguez-Gutierrez, P.R.3    Kesavalu, L.4    Satoh, M.5    Chan, E.K.6
  • 40
    • 84892422964 scopus 로고    scopus 로고
    • Tumor necrosis factor receptor associated factor-4: An adapter protein overexpressed in metastatic prostate cancer is regulated by microRNA-29a
    • Ahmed F, Shiraishi T, Vessella RL and Kulkarni P: Tumor necrosis factor receptor associated factor-4: An adapter protein overexpressed in metastatic prostate cancer is regulated by microRNA-29a. Oncol Rep 30: 2963-2968, 2013.
    • (2013) Oncol Rep , vol.30 , pp. 2963-2968
    • Ahmed, F.1    Shiraishi, T.2    Vessella, R.L.3    Kulkarni, P.4
  • 42
    • 80052440185 scopus 로고    scopus 로고
    • MicroRNA regulation of innate immune responsesin epithelial cells
    • Zhou R, O'Hara SP and Chen XM: MicroRNA regulation of innate immune responsesin epithelial cells. Cell Mol Immunol 8: 371-379, 2011.
    • (2011) Cell Mol Immunol , vol.8 , pp. 371-379
    • Zhou, R.1    O'Hara, S.P.2    Chen, X.M.3
  • 43
    • 84862138718 scopus 로고    scopus 로고
    • Cloning and functional characterization of rat stimulator of interferon genes (STING) regulated by MIR-24
    • Huang Z, Chen X, Yu B and Chen D: Cloning and functional characterization of rat stimulator of interferon genes (STING) regulated by MIR-24. Dev Comp Immunol 37: 414-420, 2012.
    • (2012) Dev Comp Immunol , vol.37 , pp. 414-420
    • Huang, Z.1    Chen, X.2    Yu, B.3    Chen, D.4
  • 44
    • 84878810703 scopus 로고    scopus 로고
    • Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis
    • Lai NS, Yu HC, Chen HC, Yu CL, Huang HB and Lu MC: Aberrant expression of microRNAs in T cells from patients with ankylosing spondylitis contributes to the immunopathogenesis. Clin Exp Immunol 173: 47-57, 2013.
    • (2013) Clin Exp Immunol , vol.173 , pp. 47-57
    • Lai, N.S.1    Yu, H.C.2    Chen, H.C.3    Yu, C.L.4    Huang, H.B.5    Lu, M.C.6
  • 45
    • 84863046014 scopus 로고    scopus 로고
    • Downregulation of PCAF by MIR-181a/b provides feedback regulation to TNF-α-induced transcription of proinflammatory genes in liver epithelial cells
    • Zhao J, Gong AY, Zhou R, Liu J, Eischeid AN and Chen XM: Downregulation of PCAF by MIR-181a/b provides feedback regulation to TNF-α-induced transcription of proinflammatory genes in liver epithelial cells. J Immunol 188: 1266-1274, 2012.
    • (2012) J Immunol , vol.188 , pp. 1266-1274
    • Zhao, J.1    Gong, A.Y.2    Zhou, R.3    Liu, J.4    Eischeid, A.N.5    Chen, X.M.6
  • 47
    • 79955022118 scopus 로고    scopus 로고
    • Both MIR-17-5p and MIR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression
    • Zhang M, Liu Q, Mi S, Liang X, Zhang Z, Su X, Liu J, Chen Y, Wang M, Zhang Y, et al: Both MIR-17-5p and MIR-20a alleviate suppressive potential of myeloid-derived suppressor cells by modulating STAT3 expression. J Immunol 186: 4716-4724, 2011.
    • (2011) J Immunol , vol.186 , pp. 4716-4724
    • Zhang, M.1    Liu, Q.2    Mi, S.3    Liang, X.4    Zhang, Z.5    Su, X.6    Liu, J.7    Chen, Y.8    Wang, M.9    Zhang, Y.10
  • 48
    • 77951932396 scopus 로고    scopus 로고
    • MicroRNA regulation of IFN-beta protein expression: Rapid and sensitive modulation of the innate immune response
    • Witwer KW, Sisk JM, Gama L and Clements JE: MicroRNA regulation of IFN-beta protein expression: Rapid and sensitive modulation of the innate immune response. J Immunol 184: 2369-2376, 2010.
    • (2010) J Immunol , vol.184 , pp. 2369-2376
    • Witwer, K.W.1    Sisk, J.M.2    Gama, L.3    Clements, J.E.4
  • 49
    • 84875139094 scopus 로고    scopus 로고
    • MicroRNA-92a negatively regulates Toll-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase
    • Lai L, Song Y, Liu Y, Chen Q, Han Q, Chen W, Pan T, Zhang Y, Cao X and Wang Q: MicroRNA-92a negatively regulates Toll-like receptor (TLR)-triggered inflammatory response in macrophages by targeting MKK4 kinase. J Biol Chem 288: 7956-7967, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 7956-7967
    • Lai, L.1    Song, Y.2    Liu, Y.3    Chen, Q.4    Han, Q.5    Chen, W.6    Pan, T.7    Zhang, Y.8    Cao, X.9    Wang, Q.10
  • 50
    • 84859891062 scopus 로고    scopus 로고
    • MicroRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages
    • Qi J, Qiao Y, Wang P, Li S, Zhao W and Gao C: MicroRNA-210 negatively regulates LPS-induced production of proinflammatory cytokines by targeting NF-κB1 in murine macrophages. FEBS Lett 586: 1201-1207, 2012.
    • (2012) FEBS Lett , vol.586 , pp. 1201-1207
    • Qi, J.1    Qiao, Y.2    Wang, P.3    Li, S.4    Zhao, W.5    Gao, C.6
  • 51
    • 77951219696 scopus 로고    scopus 로고
    • MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization
    • Jennewein C, von Knethen A, Schmid T and Brüne B: MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization. J Biol Chem 285: 11846-11853, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 11846-11853
    • Jennewein, C.1    Von Knethen, A.2    Schmid, T.3    Brüne, B.4
  • 52
    • 65249106172 scopus 로고    scopus 로고
    • MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression
    • Lu TX, Munitz A and Rothenberg ME: MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J Immunol 182: 4994-5002, 2009.
    • (2009) J Immunol , vol.182 , pp. 4994-5002
    • Lu, T.X.1    Munitz, A.2    Rothenberg, M.E.3
  • 53
    • 78650643190 scopus 로고    scopus 로고
    • MicroRNA-101 targets MAPK phosphatase-1 to regulate the activation of MAPKs in macrophages
    • Zhu QY, Liu Q, Chen JX, Lan K and Ge BX: MicroRNA-101 targets MAPK phosphatase-1 to regulate the activation of MAPKs in macrophages. J Immunol 185: 7435-7442, 2010.
    • (2010) J Immunol , vol.185 , pp. 7435-7442
    • Zhu, Q.Y.1    Liu, Q.2    Chen, J.X.3    Lan, K.4    Ge, B.X.5
  • 54
    • 78650645817 scopus 로고    scopus 로고
    • MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα
    • Liu X, Zhan Z, Xu L, Ma F, Li D, Guo Z, Li N and Cao X: MicroRNA-148/152 impair innate response and antigen presentation of TLR-triggered dendritic cells by targeting CaMKIIα. J Immunol 185: 7244-7251, 2010.
    • (2010) J Immunol , vol.185 , pp. 7244-7251
    • Liu, X.1    Zhan, Z.2    Xu, L.3    Ma, F.4    Li, D.5    Guo, Z.6    Li, N.7    Cao, X.8
  • 55
    • 84887039967 scopus 로고    scopus 로고
    • The expression and role of MIR-301a in human umbilical cord-derived mesenchymal stromal cells
    • Ma F, Chen D, Chi Y, Chen F, Li X and Han Z: The expression and role of MIR-301a in human umbilical cord-derived mesenchymal stromal cells. Cytotherapy 15: 1511-1516, 2013.
    • (2013) Cytotherapy , vol.15 , pp. 1511-1516
    • Ma, F.1    Chen, D.2    Chi, Y.3    Chen, F.4    Li, X.5    Han, Z.6
  • 56
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S and Takeuchi O: Pathogen recognition and innate immunity. Cell 124: 783-801, 2006.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 58
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C and Medzhitov R: Toll-like receptors: Linking innate and adaptive immunity. Adv Exp Med Biol 560: 11-18, 2005.
    • (2005) Adv Exp Med Biol , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 59
    • 33750574752 scopus 로고    scopus 로고
    • TLR signaling pathways: Opportunities for activation and blockade in pursuit of therapy
    • Hoebe K, Jiang Z, Georgel P, Tabeta K, Janssen E, Du X and Beutler B: TLR signaling pathways: Opportunities for activation and blockade in pursuit of therapy. Curr Pharm Des 12: 4123-4134, 2006.
    • (2006) Curr Pharm des , vol.12 , pp. 4123-4134
    • Hoebe, K.1    Jiang, Z.2    Georgel, P.3    Tabeta, K.4    Janssen, E.5    Du, X.6    Beutler, B.7
  • 61
    • 34247566510 scopus 로고    scopus 로고
    • The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
    • O'Neill LA and Bowie AG: The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 7: 353-364, 2007.
    • (2007) Nat Rev Immunol , vol.7 , pp. 353-364
    • O'Neill, L.A.1    Bowie, A.G.2
  • 62
    • 77954551154 scopus 로고    scopus 로고
    • Modulation of adult mesenchymal stem cells activity by toll-like receptors: Implications on therapeutic potential
    • DelaRosa O and Lombardo E: Modulation of adult mesenchymal stem cells activity by toll-like receptors: Implications on therapeutic potential. Mediators Inflamm 2010: 865601, 2010.
    • (2010) Mediators Inflamm , vol.2010 , pp. 865601
    • DelaRosa, O.1    Lombardo, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.