Cloning and functional characterization of rat stimulator of interferon genes (STING) regulated by miR-24

Developmental and Comparative Immunology

Volumn 37, Issue 3-4, 2012, Pages 414-420

  Huang, Zhiqing ^a   Chen, Xiaoling ^a   Yu, Bing ^a   Chen, Daiwen ^a  

^a SICHUAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

Cloning; IEC 6 cells; IFN ; MiR 24; Rat STING

Indexed keywords

BETA INTERFERON; COMPLEMENTARY DNA; MESSENGER RNA; MICRORNA 24; POLYINOSINIC POLYCYTIDYLIC ACID;

3' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA FLANKING REGION; DOWN REGULATION; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC IDENTIFICATION; GENETIC TRANSFECTION; INTERFERON BETA GENE; LYMPH NODE; MALE; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PANCREAS DUCT; PRIORITY JOURNAL; PROTEIN DOMAIN; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATOR GENE; SEQUENCE HOMOLOGY; SPLEEN; STIMULATOR OF INTERFERON GENE; TISSUE DISTRIBUTION; UPREGULATION;

ANIMALIA; BOS; MAMMALIA; PAN; RATTUS; SUIDAE;

EID: 84862138718     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2012.02.010     Document Type: Article

References (27)

1. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
2. Alexopoulou L., Holt A.C., Medzhitov R., Flavell R.A. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 2001, 413:732-738.
3. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
4. Djuranovic S., Nahvi A., Green R. A parsimonious model for gene regulation by miRNAs. Science 2011, 331:550-553.
5. Frey A.B. Study of immune response to tumors in the rat. Methods 1997, 12:173-188.
6. Gitlin L., Barchet W., Gilfillan S., Cella M., Beutler B., Flavell R.A., Diamond M.S., Colonna M. Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus. Proc. Natl. Acad. Sci. USA 2006, 103:8459-8464.
7. Hobert O. Gene regulation by transcription factors and microRNAs. Science 2008, 319:1785-1786.
8. Huang Z., Chen X., Zhang K., Yu B., Mao X., Zhao Y., Chen D. Molecular cloning and functional characterization of Tibetan porcine STING. Int. J. Mol. Sci. 2012, 13:506-515.
9. Ishikawa H., Barber G.N. STING is an endoplasmic reticulum adaptor that facilitates innate immune signaling. Nature 2008, 455:674-678.
10. Kawai T., Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int. Immunol. 2009, 21:317-337.
11. Kumagai Y., Takeuchi O., Akira S. Pathogen recognition by innate receptors. J. Infect. Chemother. 2008, 14:86-92.
12. T method. Methods 2001, 25:402-408.
13. Maldonado-Contreras A.L., McCormick B.A. Intestinal epithelial cells and their role in innate mucosal immunity. Cell Tissue Res. 2011, 343:5-12.
14. Nakhaei P., Hiscott J., Lin R. STING-ing the antiviral pathway. J. Mol. Cell. Biol. 2010, 2:110-112.
15. Pfaffl M.W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001, 29:e45.
16. Quaroni A., Wands J., Trelstad R.L., Isselbacher K.J. Epithelioid cell cultures from rat small intestine: characterization by morphologic and immunological criteria. J. Cell. Biol. 1979, 80:248-265.
17. Shao L., Serrano D., Mayer L. The role of epithelial cells in immune regulation in the gut. Semin. Immunol. 2001, 13:163-175.
18. Sun W., Li Y., Chen L., Chen H., You F., Zhou X., Zhou Y., Zhai Z., Chen D., Jiang Z. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc. Natl. Acad. Sci. USA 2009, 106:8653-8658.
19. Takeuchi O., Akira S. Recognition of viruses by innate immunity. Immunol. Rev. 2007, 220:214-224.
20. Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
21. Xie L., Liu M., Fang L., Su X., Cai K., Wang D., Chen H., Xiao S. Molecular cloning and functional characterization of porcine stimulator of interferon genes (STING). Dev. Comp. Immunol. 2010, 34:847-854.
22. Yoneyama M., Fujita T. RNA recognition and signal transduction by RIG-I-like receptors. Immunol. Rev. 2009, 227:54-65.
23. Yoneyama M., Fujita T. Recognition of viral nucleic acids in innate immunity. Rev. Med. Virol. 2010, 20:4-22.
24. Yoneyama M., Kikuchi M., Natsukawa T., Shinobu N., Imaizumi T., Miyagishi M., Taira K., Akira S., Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 2004, 5:730-737.
25. Yoneyama M., Kikuchi M., Matsumoto K., Imaizumi T., Miyagishi M., Taira K., Foy E., Loo Y.M., Gale M., Akira S., Yonehara S., Kato A., Fujita T. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J. Immunol. 2005, 175:2851-2858.
26. Zeng W., Chen Z.J. MITAgating viral infection. Immunity 2008, 29:513-515.
27. Zhong B., Yang Y., Li S., Wang Y.Y., Li Y., Diao F., Lei C., He X., Zhang L., Tien P., Shu H.B. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity 2008, 29:538-550.