-
1
-
-
84865727393
-
The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
-
Derrien,T., Johnson,R., Bussotti,G., Tanzer,A., Djebali,S., Tilgner,H., Guernec,G., Martin,D., Merkel,A., Knowles,D.G. et al. (2012) The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. Genome Res., 22, 1775-1789.
-
(2012)
Genome Res.
, vol.22
, pp. 1775-1789
-
-
Derrien, T.1
Johnson, R.2
Bussotti, G.3
Tanzer, A.4
Djebali, S.5
Tilgner, H.6
Guernec, G.7
Martin, D.8
Merkel, A.9
Knowles, D.G.10
-
2
-
-
84924063355
-
The landscape of long noncoding RNAs in the human transcriptome
-
Iyer,M.K., Niknafs,Y.S., Malik,R., Singhal,U., Sahu,A., Hosono,Y., Barrette,T.R., Prensner,J.R., Evans,J.R., Zhao,S. et al. (2015) The landscape of long noncoding RNAs in the human transcriptome. Nat. Genet., 47, 199-208.
-
(2015)
Nat. Genet.
, vol.47
, pp. 199-208
-
-
Iyer, M.K.1
Niknafs, Y.S.2
Malik, R.3
Singhal, U.4
Sahu, A.5
Hosono, Y.6
Barrette, T.R.7
Prensner, J.R.8
Evans, J.R.9
Zhao, S.10
-
3
-
-
84917705502
-
A pathophysiological view of the long non-coding RNA world
-
Di Gesualdo,F., Capaccioli,S. and Lulli,M. (2014) A pathophysiological view of the long non-coding RNA world. Oncotarget, 5, 10976-10996.
-
(2014)
Oncotarget
, vol.5
, pp. 10976-10996
-
-
Di Gesualdo, F.1
Capaccioli, S.2
Lulli, M.3
-
4
-
-
84922232458
-
Long non-coding RNAs as emerging regulators of differentiation, development, and disease
-
Dey,B.K., Mueller,A.C. and Dutta,A. (2014) Long non-coding RNAs as emerging regulators of differentiation, development, and disease. Transcription, 5, e944014.
-
(2014)
Transcription
, vol.5
-
-
Dey, B.K.1
Mueller, A.C.2
Dutta, A.3
-
5
-
-
84896823260
-
LncRNAs: New Players in Apoptosis Control
-
Rossi,M.N. and Antonangeli,F. (2014) LncRNAs: New Players in Apoptosis Control. Int. J. Cell Biol., 2014, e473857.
-
(2014)
Int. J. Cell Biol.
, vol.2014
-
-
Rossi, M.N.1
Antonangeli, F.2
-
6
-
-
84907911172
-
The functional role of long non-coding RNAs and epigenetics
-
Cao,J. (2014) The functional role of long non-coding RNAs and epigenetics. Biol.Proced.Online, 16, e11.
-
(2014)
Biol.Proced.Online
, vol.16
, pp. e11
-
-
Cao, J.1
-
7
-
-
84861904178
-
Genome regulation by long noncoding RNAs
-
Rinn,J.L. and Chang,H.Y. (2012) Genome regulation by long noncoding RNAs. Annu. Rev. Biochem., 81, 145-166.
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 145-166
-
-
Rinn, J.L.1
Chang, H.Y.2
-
8
-
-
84878451215
-
Gene regulation by the act of long non-coding RNA transcription
-
Kornienko,A.E., Guenzl,P.M., Barlow,D.P. and Pauler,F.M. (2013) Gene regulation by the act of long non-coding RNA transcription. BMC Biol., 11, e59.
-
(2013)
BMC Biol.
, vol.11
, pp. e59
-
-
Kornienko, A.E.1
Guenzl, P.M.2
Barlow, D.P.3
Pauler, F.M.4
-
9
-
-
84860119507
-
Long non-coding RNAs: Versatile master regulators of gene expression and crucial players in cancer
-
Nie,L., Wu,H.J., Hsu,J.M., Chang,S.S., Labaff,A.M., Li,C.W., Wang,Y., Hsu,J.L. and Hung,M.C. (2012) Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer. Am. J. Transl. Res., 4, 127-150.
-
(2012)
Am. J. Transl. Res.
, vol.4
, pp. 127-150
-
-
Nie, L.1
Wu, H.J.2
Hsu, J.M.3
Chang, S.S.4
Labaff, A.M.5
Li, C.W.6
Wang, Y.7
Hsu, J.L.8
Hung, M.C.9
-
10
-
-
84866947025
-
Emerging roles for long non-coding rnas in cancer and neurological disorders
-
Niland,C.N., Merry,C.R. and Khalil,A.M. (2012) Emerging roles for long non-coding rnas in cancer and neurological disorders. Front. Genet., 3, e25.
-
(2012)
Front. Genet.
, vol.3
, pp. e25
-
-
Niland, C.N.1
Merry, C.R.2
Khalil, A.M.3
-
11
-
-
84912097412
-
The decalog of long non-coding RNA involvement in cancer diagnosis and monitoring
-
Kunej,T., Obsteter,J., Pogacar,Z., Horvat,S. and Calin,G.A. (2014) The decalog of long non-coding RNA involvement in cancer diagnosis and monitoring. Crit. Rev. Clin. Lab. Sci., 51, 344-357.
-
(2014)
Crit. Rev. Clin. Lab. Sci.
, vol.51
, pp. 344-357
-
-
Kunej, T.1
Obsteter, J.2
Pogacar, Z.3
Horvat, S.4
Calin, G.A.5
-
12
-
-
84889022338
-
Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer
-
Weber,D.G., Johnen,G., Casjens,S., Bryk,O., Pesch,B., Jockel,K.H., Kollmeier,J. and Bruning,T. (2013) Evaluation of long noncoding RNA MALAT1 as a candidate blood-based biomarker for the diagnosis of non-small cell lung cancer. BMC Res. Notes, 6, e518.
-
(2013)
BMC Res. Notes
, vol.6
, pp. e518
-
-
Weber, D.G.1
Johnen, G.2
Casjens, S.3
Bryk, O.4
Pesch, B.5
Jockel, K.H.6
Kollmeier, J.7
Bruning, T.8
-
13
-
-
84879987789
-
LincRNAs: Genomics, evolution, and mechanisms
-
Ulitsky,I. and Bartel,D.P. (2013) lincRNAs: genomics, evolution, and mechanisms. Cell, 154, 26-46.
-
(2013)
Cell
, vol.154
, pp. 26-46
-
-
Ulitsky, I.1
Bartel, D.P.2
-
14
-
-
84894532371
-
On the classification of long non-coding RNAs
-
Ma,L., Bajic,V.B. and Zhang,Z. (2013) On the classification of long non-coding RNAs. RNA Biol., 10, 925-933.
-
(2013)
RNA Biol.
, vol.10
, pp. 925-933
-
-
Ma, L.1
Bajic, V.B.2
Zhang, Z.3
-
15
-
-
84891711873
-
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes
-
van Heesch,S., van Iterson,M., Jacobi,J., Boymans,S., Essers,P.B., de Bruijn,E., Hao,W., MacInnes,A.W., Cuppen,E. and Simonis,M. (2014) Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol., 15,R6.
-
(2014)
Genome Biol., 15,R6
-
-
Van Heesch, S.1
Van Iterson, M.2
Jacobi, J.3
Boymans, S.4
Essers, P.B.5
De Bruijn, E.6
Hao, W.7
MacInnes, A.W.8
Cuppen, E.9
Simonis, M.10
-
16
-
-
84939171986
-
Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution
-
Cabili,M.N., Dunagin,M.C., McClanahan,P.D., Biaesch,A., Padovan-Merhar,O., Regev,A., Rinn,J.L. and Raj,A. (2015) Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution. Genome Biol., 16, e20.
-
(2015)
Genome Biol.
, vol.16
, pp. e20
-
-
Cabili, M.N.1
Dunagin, M.C.2
McClanahan, P.D.3
Biaesch, A.4
Padovan-Merhar, O.5
Regev, A.6
Rinn, J.L.7
Raj, A.8
-
17
-
-
0005772676
-
Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide
-
Stephenson,M.L. and Zamecnik,P.C. (1978) Inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc. Natl. Acad. Sci. U.S.A., 75, 285-288.
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 285-288
-
-
Stephenson, M.L.1
Zamecnik, P.C.2
-
18
-
-
0023498624
-
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
-
Inoue,H., Hayase,Y., Iwai,S. and Ohtsuka,E. (1987) Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. Nucleic Acids Symp. Ser., 18, 221-224.
-
(1987)
Nucleic Acids Symp. Ser.
, vol.18
, pp. 221-224
-
-
Inoue, H.1
Hayase, Y.2
Iwai, S.3
Ohtsuka, E.4
-
19
-
-
0027168725
-
Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression
-
Monia,B.P., Lesnik,E.A., Gonzalez,C., Lima,W.F., McGee,D., Guinosso,C.J., Kawasaki,A.M., Cook,P.D. and Freier,S.M. (1993) Evaluation of 2′-modified oligonucleotides containing 2′-deoxy gaps as antisense inhibitors of gene expression. J. Biol. Chem., 268, 14514-14522.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 14514-14522
-
-
Monia, B.P.1
Lesnik, E.A.2
Gonzalez, C.3
Lima, W.F.4
McGee, D.5
Guinosso, C.J.6
Kawasaki, A.M.7
Cook, P.D.8
Freier, S.M.9
-
20
-
-
2342427578
-
Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs
-
Wu,H., Lima,W.F., Zhang,H., Fan,A., Sun,H. and Crooke,S.T. (2004) Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugs. J. Biol. Chem., 279, 17181-17189.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 17181-17189
-
-
Wu, H.1
Lima, W.F.2
Zhang, H.3
Fan, A.4
Sun, H.5
Crooke, S.T.6
-
21
-
-
77957849949
-
An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1
-
Suzuki,Y., Holmes,J.B., Cerritelli,S.M., Sakhuja,K., Minczuk,M., Holt,I.J. and Crouch,R.J. (2010) An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1. Mol. Cell. Biol., 30, 5123-5134.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5123-5134
-
-
Suzuki, Y.1
Holmes, J.B.2
Cerritelli, S.M.3
Sakhuja, K.4
Minczuk, M.5
Holt, I.J.6
Crouch, R.J.7
-
22
-
-
0037470145
-
Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis
-
Vickers,T.A., Koo,S., Bennett,C.F., Crooke,S.T., Dean,N.M. and Baker,B.F. (2003) Efficient reduction of target RNAs by small interfering RNA and RNase H-dependent antisense agents. A comparative analysis. J. Biol. Chem., 278, 7108-7118.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7108-7118
-
-
Vickers, T.A.1
Koo, S.2
Bennett, C.F.3
Crooke, S.T.4
Dean, N.M.5
Baker, B.F.6
-
23
-
-
26844440157
-
Regulating gene expression through RNA nuclear retention
-
Prasanth,K.V., Prasanth,S.G., Xuan,Z., Hearn,S., Freier,S.M., Bennett,C.F., Zhang,M.Q. and Spector,D.L. (2005) Regulating gene expression through RNA nuclear retention. Cell, 123, 249-263.
-
(2005)
Cell
, vol.123
, pp. 249-263
-
-
Prasanth, K.V.1
Prasanth, S.G.2
Xuan, Z.3
Hearn, S.4
Freier, S.M.5
Bennett, C.F.6
Zhang, M.Q.7
Spector, D.L.8
-
24
-
-
84864439453
-
Targeting nuclear RNA for in vivo correction of myotonic dystrophy
-
Wheeler,T.M., Leger,A.J., Pandey,S.K., MacLeod,A.R., Nakamori,M., Cheng,S.H., Wentworth,B.M., Bennett,C.F. and Thornton,C.A. (2012) Targeting nuclear RNA for in vivo correction of myotonic dystrophy. Nature, 488, 111-115.
-
(2012)
Nature
, vol.488
, pp. 111-115
-
-
Wheeler, T.M.1
Leger, A.J.2
Pandey, S.K.3
MacLeod, A.R.4
Nakamori, M.5
Cheng, S.H.6
Wentworth, B.M.7
Bennett, C.F.8
Thornton, C.A.9
-
25
-
-
0026052924
-
Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms
-
Chiang,M.Y., Chan,H., Zounes,M.A., Freier,S.M., Lima,W.F. and Bennett,C.F. (1991) Antisense oligonucleotides inhibit intercellular adhesion molecule 1 expression by two distinct mechanisms. J. Biol. Chem., 266, 18162-18171.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18162-18171
-
-
Chiang, M.Y.1
Chan, H.2
Zounes, M.A.3
Freier, S.M.4
Lima, W.F.5
Bennett, C.F.6
-
26
-
-
0041582974
-
Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide
-
Zamecnik,P.C. and Stephenson,M.L. (1978) Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. U.S.A., 75, 280-284.
-
(1978)
Proc. Natl. Acad. Sci. U.S.A.
, vol.75
, pp. 280-284
-
-
Zamecnik, P.C.1
Stephenson, M.L.2
-
27
-
-
0026175462
-
Substrate specificity and kinetics of degradation of antisense oligonucleotides by a 3′ exonuclease in plasma
-
Eder,P.S., DeVine,R.J., Dagle,J.M. and Walder,J.A. (1991) Substrate specificity and kinetics of degradation of antisense oligonucleotides by a 3′ exonuclease in plasma. Antisense Res. Dev., 1, 141-151.
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 141-151
-
-
Eder, P.S.1
DeVine, R.J.2
Dagle, J.M.3
Walder, J.A.4
-
28
-
-
84884252518
-
Improved performance of anti-mirna oligonucleotides using a novel non-nucleotide modifier
-
Lennox,K.A., Owczarzy,R., Thomas,D.M., Walder,J.A. and Behlke,M.A. (2013) Improved performance of anti-mirna oligonucleotides using a novel non-nucleotide modifier. Mol. Ther. Nucleic Acids., 2, e117.
-
(2013)
Mol. Ther. Nucleic Acids.
, vol.2
, pp. e117
-
-
Lennox, K.A.1
Owczarzy, R.2
Thomas, D.M.3
Walder, J.A.4
Behlke, M.A.5
-
29
-
-
0037733977
-
Antisense technologies. Improvement through novel chemical modifications
-
Kurreck,J. (2003) Antisense technologies. Improvement through novel chemical modifications. Eur. J. Biochem., 270, 1628-1644.
-
(2003)
Eur. J. Biochem.
, vol.270
, pp. 1628-1644
-
-
Kurreck, J.1
-
30
-
-
0023650861
-
Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H
-
Inoue,H., Hayase,Y., Iwai,S. and Ohtsuka,E. (1987) Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H. FEBS Lett., 215, 327-330.
-
(1987)
FEBS Lett.
, vol.215
, pp. 327-330
-
-
Inoue, H.1
Hayase, Y.2
Iwai, S.3
Ohtsuka, E.4
-
31
-
-
0023650976
-
Site-directed cleavage of RNA
-
Shibahara,S., Mukai,S., Nishihara,T., Inoue,H., Ohtsuka,E. and Morisawa,H. (1987) Site-directed cleavage of RNA. Nucleic Acids Res., 15, 4403-4415.
-
(1987)
Nucleic Acids Res.
, vol.15
, pp. 4403-4415
-
-
Shibahara, S.1
Mukai, S.2
Nishihara, T.3
Inoue, H.4
Ohtsuka, E.5
Morisawa, H.6
-
32
-
-
80052913097
-
An overview of sugar-modified oligonucleotides for antisense therapeutics
-
Prakash,T.P. (2011) An overview of sugar-modified oligonucleotides for antisense therapeutics. Chem. Biodivers, 8, 1616-1641.
-
(2011)
Chem. Biodivers
, vol.8
, pp. 1616-1641
-
-
Prakash, T.P.1
-
33
-
-
33645817932
-
Characterization of modified antisense oligonucleotides in Xenopus laevis embryos
-
Lennox,K.A., Sabel,J.L., Johnson,M.J., Moreira,B.G., Fletcher,C.A., Rose,S.D., Behlke,M.A., Laikhter,A.L., Walder,J.A. and Dagle,J.M. (2006) Characterization of modified antisense oligonucleotides in Xenopus laevis embryos. Oligonucleotides, 16, 26-42.
-
(2006)
Oligonucleotides
, vol.16
, pp. 26-42
-
-
Lennox, K.A.1
Sabel, J.L.2
Johnson, M.J.3
Moreira, B.G.4
Fletcher, C.A.5
Rose, S.D.6
Behlke, M.A.7
Laikhter, A.L.8
Walder, J.A.9
Dagle, J.M.10
-
34
-
-
77956519356
-
A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo
-
Gupta,N., Fisker,N., Asselin,M.C., Lindholm,M., Rosenbohm,C., Orum,H., Elmen,J., Seidah,N.G. and Straarup,E.M. (2010) A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo. PLoS One, 5, e10682.
-
(2010)
PLoS One
, vol.5
-
-
Gupta, N.1
Fisker, N.2
Asselin, M.C.3
Lindholm, M.4
Rosenbohm, C.5
Orum, H.6
Elmen, J.7
Seidah, N.G.8
Straarup, E.M.9
-
35
-
-
3242677639
-
siRNAs: Applications in functional genomics and potential as therapeutics
-
Dorsett,Y. and Tuschl,T. (2004) siRNAs: applications in functional genomics and potential as therapeutics. Nat. Rev. Drug Discov., 3, 318-329.
-
(2004)
Nat. Rev. Drug Discov.
, vol.3
, pp. 318-329
-
-
Dorsett, Y.1
Tuschl, T.2
-
36
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir,S.M., Harborth,J., Lendeckel,W., Yalcin,A., Weber,K. and Tuschl,T. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
37
-
-
13844281898
-
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
-
Kim,D.H., Behlke,M.A., Rose,S.D., Chang,M.S., Choi,S. and Rossi,J.J. (2005) Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat. Biotechnol., 23, 222-226.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
38
-
-
22844448088
-
Functional polarity is introduced by Dicer processing of short substrate RNAs
-
Rose,S.D., Kim,D.H., Amarzguioui,M., Heidel,J.D., Collingwood,M.A., Davis,M.E., Rossi,J.J. and Behlke,M.A. (2005) Functional polarity is introduced by Dicer processing of short substrate RNAs. Nucleic Acids Res., 33, 4140-4156.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 4140-4156
-
-
Rose, S.D.1
Kim, D.H.2
Amarzguioui, M.3
Heidel, J.D.4
Collingwood, M.A.5
Davis, M.E.6
Rossi, J.J.7
Behlke, M.A.8
-
39
-
-
84880213957
-
Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants
-
Snead,N.M., Wu,X., Li,A., Cui,Q., Sakurai,K., Burnett,J.C. and Rossi,J.J. (2013) Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants. Nucleic Acids Res., 41, 6209-6221.
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 6209-6221
-
-
Snead, N.M.1
Wu, X.2
Li, A.3
Cui, Q.4
Sakurai, K.5
Burnett, J.C.6
Rossi, J.J.7
-
40
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
Behlke,M.A. (2008) Chemical modification of siRNAs for in vivo use. Oligonucleotides, 18, 305-320.
-
(2008)
Oligonucleotides
, vol.18
, pp. 305-320
-
-
Behlke, M.A.1
-
41
-
-
84860353437
-
Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
-
Modarresi,F., Faghihi,M.A., Lopez-Toledano,M.A., Fatemi,R.P., Magistri,M., Brothers,S.P., van der Brug,M.P. and Wahlestedt,C. (2012) Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat. Biotechnol., 30, 453-459.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 453-459
-
-
Modarresi, F.1
Faghihi, M.A.2
Lopez-Toledano, M.A.3
Fatemi, R.P.4
Magistri, M.5
Brothers, S.P.6
Van Der Brug, M.P.7
Wahlestedt, C.8
-
42
-
-
84901277130
-
Involvement of satellite I noncoding RNA in regulation of chromosome segregation
-
Ideue,T., Cho,Y., Nishimura,K. and Tani,T. (2014) Involvement of satellite I noncoding RNA in regulation of chromosome segregation. Genes Cells, 19, 528-538.
-
(2014)
Genes Cells
, vol.19
, pp. 528-538
-
-
Ideue, T.1
Cho, Y.2
Nishimura, K.3
Tani, T.4
-
43
-
-
67651002028
-
Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells
-
Ideue,T., Hino,K., Kitao,S., Yokoi,T. and Hirose,T. (2009) Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells. RNA, 15, 1578-1587.
-
(2009)
RNA
, vol.15
, pp. 1578-1587
-
-
Ideue, T.1
Hino, K.2
Kitao, S.3
Yokoi, T.4
Hirose, T.5
-
44
-
-
84921790730
-
Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides
-
Zong,X., Huang,L., Tripathi,V., Peralta,R., Freier,S.M., Guo,S. and Prasanth,K.V. (2015) Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides. Methods Mol. Biol., 1262, 321-331.
-
(2015)
Methods Mol. Biol.
, vol.1262
, pp. 321-331
-
-
Zong, X.1
Huang, L.2
Tripathi, V.3
Peralta, R.4
Freier, S.M.5
Guo, S.6
Prasanth, K.V.7
-
45
-
-
84892544892
-
RNAi factors are present and active in human cell nuclei
-
Gagnon,K.T., Li,L., Chu,Y., Janowski,B.A. and Corey,D.R. (2014) RNAi factors are present and active in human cell nuclei. Cell Rep., 6, 211-221.
-
(2014)
Cell Rep.
, vol.6
, pp. 211-221
-
-
Gagnon, K.T.1
Li, L.2
Chu, Y.3
Janowski, B.A.4
Corey, D.R.5
-
46
-
-
85057669819
-
-
CRC Press, Boca Raton
-
Lima,W.F., Wu,H. and Crooke,S.T. (2008) Antisense Drug Technology, Principles, Strategies, and Applications. CRC Press, Boca Raton, Vol. 2, pp. 47-74.
-
(2008)
Antisense Drug Technology, Principles, Strategies, and Applications
, vol.2
, pp. 47-74
-
-
Lima, W.F.1
Wu, H.2
Crooke, S.T.3
-
47
-
-
84882752515
-
Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing
-
Wu,H., Sun,H., Liang,X., Lima,W.F. and Crooke,S.T. (2013) Human RNase H1 is associated with protein P32 and is involved in mitochondrial pre-rRNA processing. PLoS One, 8, e71006.
-
(2013)
PLoS One
, vol.8
-
-
Wu, H.1
Sun, H.2
Liang, X.3
Lima, W.F.4
Crooke, S.T.5
-
48
-
-
84907829489
-
Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms
-
Vickers,T.A. and Crooke,S.T. (2014) Antisense oligonucleotides capable of promoting specific target mRNA reduction via competing RNase H1-dependent and independent mechanisms. PLoS One, 9, e108625.
-
(2014)
PLoS One
, vol.9
-
-
Vickers, T.A.1
Crooke, S.T.2
-
49
-
-
1942453441
-
Modification of alternative splicing by antisense therapeutics
-
Kole,R., Vacek,M. and Williams,T. (2004) Modification of alternative splicing by antisense therapeutics. Oligonucleotides, 14, 65-74.
-
(2004)
Oligonucleotides
, vol.14
, pp. 65-74
-
-
Kole, R.1
Vacek, M.2
Williams, T.3
-
50
-
-
84872533627
-
RNA interference in the nucleus: Roles for small RNAs in transcription, epigenetics and beyond
-
Castel,S.E. and Martienssen,R.A. (2013) RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond. Nat. Rev. Genet., 14, 100-112.
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 100-112
-
-
Castel, S.E.1
Martienssen, R.A.2
-
51
-
-
84876416274
-
The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing
-
Stalder,L., Heusermann,W., Sokol,L., Trojer,D., Wirz,J., Hean,J., Fritzsche,A., Aeschimann,F., Pfanzagl,V., Basselet,P. et al. (2013) The rough endoplasmatic reticulum is a central nucleation site of siRNA-mediated RNA silencing. EMBO J., 32, 1115-1127.
-
(2013)
EMBO J.
, vol.32
, pp. 1115-1127
-
-
Stalder, L.1
Heusermann, W.2
Sokol, L.3
Trojer, D.4
Wirz, J.5
Hean, J.6
Fritzsche, A.7
Aeschimann, F.8
Pfanzagl, V.9
Basselet, P.10
-
52
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
Martinez,J., Patkaniowska,A., Urlaub,H., Luhrmann,R. and Tuschl,T. (2002) Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell, 110, 563-574.
-
(2002)
Cell
, vol.110
, pp. 563-574
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
53
-
-
0036074161
-
RNA interference in human cells is restricted to the cytoplasm
-
Zeng,Y. and Cullen,B.R. (2002) RNA interference in human cells is restricted to the cytoplasm. RNA, 8, 855-860.
-
(2002)
RNA
, vol.8
, pp. 855-860
-
-
Zeng, Y.1
Cullen, B.R.2
-
54
-
-
84923572337
-
The varied roles of nuclear argonaute-small RNA complexes and avenues for therapy
-
Ross,J.P. and Kassir,Z. (2014) The varied roles of nuclear argonaute-small RNA complexes and avenues for therapy. Mol. Ther. Nucleic Acids., 3, e203.
-
(2014)
Mol. Ther. Nucleic Acids.
, vol.3
, pp. e203
-
-
Ross, J.P.1
Kassir, Z.2
-
55
-
-
33751348560
-
Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody
-
Ikeda,K., Satoh,M., Pauley,K.M., Fritzler,M.J., Reeves,W.H. and Chan,E.K. (2006) Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody. J. Immunol. Methods, 317, 38-44.
-
(2006)
J. Immunol. Methods
, vol.317
, pp. 38-44
-
-
Ikeda, K.1
Satoh, M.2
Pauley, K.M.3
Fritzler, M.J.4
Reeves, W.H.5
Chan, E.K.6
-
56
-
-
79951567064
-
Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice
-
Liang,X.H., Vickers,T.A., Guo,S. and Crooke,S.T. (2011) Efficient and specific knockdown of small non-coding RNAs in mammalian cells and in mice. Nucleic Acids Res., 39, e13.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. e13
-
-
Liang, X.H.1
Vickers, T.A.2
Guo, S.3
Crooke, S.T.4
-
57
-
-
70349127769
-
Methodological obstacles in knocking down small noncoding RNAs
-
Ploner,A., Ploner,C., Lukasser,M., Niederegger,H. and Huttenhofer,A. (2009) Methodological obstacles in knocking down small noncoding RNAs. RNA, 15, 1797-1804.
-
(2009)
RNA
, vol.15
, pp. 1797-1804
-
-
Ploner, A.1
Ploner, C.2
Lukasser, M.3
Niederegger, H.4
Huttenhofer, A.5
-
58
-
-
78649874963
-
Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter
-
Chu,Y., Yue,X., Younger,S.T., Janowski,B.A. and Corey,D.R. (2010) Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter. Nucleic Acids Res., 38, 7736-7748.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 7736-7748
-
-
Chu, Y.1
Yue, X.2
Younger, S.T.3
Janowski, B.A.4
Corey, D.R.5
-
59
-
-
44149126227
-
A multifunctional human Argonaute2-specific monoclonal antibody
-
Rudel,S., Flatley,A., Weinmann,L., Kremmer,E. and Meister,G. (2008) A multifunctional human Argonaute2-specific monoclonal antibody. RNA, 14, 1244-1253.
-
(2008)
RNA
, vol.14
, pp. 1244-1253
-
-
Rudel, S.1
Flatley, A.2
Weinmann, L.3
Kremmer, E.4
Meister, G.5
-
60
-
-
59349087552
-
Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs
-
Weinmann,L., Hock,J., Ivacevic,T., Ohrt,T., Mutze,J., Schwille,P., Kremmer,E., Benes,V., Urlaub,H. and Meister,G. (2009) Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs. Cell, 136, 496-507.
-
(2009)
Cell
, vol.136
, pp. 496-507
-
-
Weinmann, L.1
Hock, J.2
Ivacevic, T.3
Ohrt, T.4
Mutze, J.5
Schwille, P.6
Kremmer, E.7
Benes, V.8
Urlaub, H.9
Meister, G.10
-
61
-
-
84855822424
-
Intracellular localization and routing of miRNA and RNAi pathway components
-
Ohrt,T., Muetze,J., Svoboda,P. and Schwille,P. (2012) Intracellular localization and routing of miRNA and RNAi pathway components. Curr. Top Med. Chem., 12, 79-88.
-
(2012)
Curr. Top Med. Chem.
, vol.12
, pp. 79-88
-
-
Ohrt, T.1
Muetze, J.2
Svoboda, P.3
Schwille, P.4
-
62
-
-
15544363403
-
Specific and potent RNAi in the nucleus of human cells
-
Robb,G.B., Brown,K.M., Khurana,J. and Rana,T.M. (2005) Specific and potent RNAi in the nucleus of human cells. Nat. Struct. Mol. Biol., 12, 133-137.
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 133-137
-
-
Robb, G.B.1
Brown, K.M.2
Khurana, J.3
Rana, T.M.4
-
63
-
-
56649122127
-
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells
-
Ohrt,T., Mutze,J., Staroske,W., Weinmann,L., Hock,J., Crell,K., Meister,G. and Schwille,P. (2008) Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells. Nucleic Acids Res., 36, 6439-6449.
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 6439-6449
-
-
Ohrt, T.1
Mutze, J.2
Staroske, W.3
Weinmann, L.4
Hock, J.5
Crell, K.6
Meister, G.7
Schwille, P.8
-
64
-
-
0038137215
-
Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2x3 receptor
-
Hemmings-Mieszczak,M., Dorn,G., Natt,F.J., Hall,J. and Wishart,W.L. (2003) Independent combinatorial effect of antisense oligonucleotides and RNAi-mediated specific inhibition of the recombinant rat P2x3 receptor. Nucleic Acids Res., 31, 2117-2126.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2117-2126
-
-
Hemmings-Mieszczak, M.1
Dorn, G.2
Natt, F.J.3
Hall, J.4
Wishart, W.L.5
-
65
-
-
84876003231
-
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB
-
Tripathi,V., Shen,Z., Chakraborty,A., Giri,S., Freier,S.M., Wu,X., Zhang,Y., Gorospe,M., Prasanth,S.G., Lal,A. et al. (2013) Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet., 9, e1003368.
-
(2013)
PLoS Genet.
, vol.9
-
-
Tripathi, V.1
Shen, Z.2
Chakraborty, A.3
Giri, S.4
Freier, S.M.5
Wu, X.6
Zhang, Y.7
Gorospe, M.8
Prasanth, S.G.9
Lal, A.10
-
66
-
-
84864033675
-
Malat1 is not an essential component of nuclear speckles in mice
-
Nakagawa,S., Ip,J.Y., Shioi,G., Tripathi,V., Zong,X., Hirose,T. and Prasanth,K.V. (2012) Malat1 is not an essential component of nuclear speckles in mice. RNA, 18, 1487-1499.
-
(2012)
RNA
, vol.18
, pp. 1487-1499
-
-
Nakagawa, S.1
Ip, J.Y.2
Shioi, G.3
Tripathi, V.4
Zong, X.5
Hirose, T.6
Prasanth, K.V.7
-
67
-
-
77956927823
-
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation
-
Tripathi,V., Ellis,J.D., Shen,Z., Song,D.Y., Pan,Q., Watt,A.T., Freier,S.M., Bennett,C.F., Sharma,A., Bubulya,P.A. et al. (2010) The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol. Cell, 39, 925-938.
-
(2010)
Mol. Cell
, vol.39
, pp. 925-938
-
-
Tripathi, V.1
Ellis, J.D.2
Shen, Z.3
Song, D.Y.4
Pan, Q.5
Watt, A.T.6
Freier, S.M.7
Bennett, C.F.8
Sharma, A.9
Bubulya, P.A.10
-
68
-
-
84924174271
-
Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma
-
Hu,L., Wu,Y., Tan,D., Meng,H., Wang,K., Bai,Y. and Yang,K. (2015) Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma. J. Exp. Clin. Cancer Res., 34, e7.
-
(2015)
J. Exp. Clin. Cancer Res.
, vol.34
, pp. e7
-
-
Hu, L.1
Wu, Y.2
Tan, D.3
Meng, H.4
Wang, K.5
Bai, Y.6
Yang, K.7
-
69
-
-
0344429906
-
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer
-
Ji,P., Diederichs,S., Wang,W., Boing,S., Metzger,R., Schneider,P.M., Tidow,N., Brandt,B., Buerger,H., Bulk,E. et al. (2003) MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene, 22, 8031-8041.
-
(2003)
Oncogene
, vol.22
, pp. 8031-8041
-
-
Ji, P.1
Diederichs, S.2
Wang, W.3
Boing, S.4
Metzger, R.5
Schneider, P.M.6
Tidow, N.7
Brandt, B.8
Buerger, H.9
Bulk, E.10
-
70
-
-
84901715681
-
MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway
-
Wu,X.S., Wang,X.A., Wu,W.G., Hu,Y.P., Li,M.L., Ding,Q., Weng,H., Shu,Y.J., Liu,T.Y., Jiang,L. et al. (2014) MALAT1 promotes the proliferation and metastasis of gallbladder cancer cells by activating the ERK/MAPK pathway. Cancer Biol. Ther., 15, 806-814.
-
(2014)
Cancer Biol. Ther.
, vol.15
, pp. 806-814
-
-
Wu, X.S.1
Wang, X.A.2
Wu, W.G.3
Hu, Y.P.4
Li, M.L.5
Ding, Q.6
Weng, H.7
Shu, Y.J.8
Liu, T.Y.9
Jiang, L.10
-
71
-
-
61849113891
-
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles
-
Sunwoo,H., Dinger,M.E., Wilusz,J.E., Amaral,P.P., Mattick,J.S. and Spector,D.L. (2009) MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res., 19, 347-359.
-
(2009)
Genome Res.
, vol.19
, pp. 347-359
-
-
Sunwoo, H.1
Dinger, M.E.2
Wilusz, J.E.3
Amaral, P.P.4
Mattick, J.S.5
Spector, D.L.6
-
72
-
-
62449319486
-
MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles
-
Sasaki,Y.T., Ideue,T., Sano,M., Mituyama,T. and Hirose,T. (2009) MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles. Proc. Natl. Acad. Sci. U.S.A., 106, 2525-2530.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 2525-2530
-
-
Sasaki, Y.T.1
Ideue, T.2
Sano, M.3
Mituyama, T.4
Hirose, T.5
-
73
-
-
62549117314
-
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles
-
Clemson,C.M., Hutchinson,J.N., Sara,S.A., Ensminger,A.W., Fox,A.H., Chess,A. and Lawrence,J.B. (2009) An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol. Cell, 33, 717-726.
-
(2009)
Mol. Cell
, vol.33
, pp. 717-726
-
-
Clemson, C.M.1
Hutchinson, J.N.2
Sara, S.A.3
Ensminger, A.W.4
Fox, A.H.5
Chess, A.6
Lawrence, J.B.7
-
74
-
-
84891800602
-
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
-
Hirose,T., Virnicchi,G., Tanigawa,A., Naganuma,T., Li,R., Kimura,H., Yokoi,T., Nakagawa,S., Benard,M., Fox,A.H. et al. (2014) NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies. Mol. Biol. Cell, 25, 169-183.
-
(2014)
Mol. Biol. Cell
, vol.25
, pp. 169-183
-
-
Hirose, T.1
Virnicchi, G.2
Tanigawa, A.3
Naganuma, T.4
Li, R.5
Kimura, H.6
Yokoi, T.7
Nakagawa, S.8
Benard, M.9
Fox, A.H.10
-
75
-
-
84862777038
-
Long non-coding RNAs in Huntington's disease neurodegeneration
-
Johnson,R. (2012) Long non-coding RNAs in Huntington's disease neurodegeneration. Neurobiol. Dis., 46, 245-254.
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 245-254
-
-
Johnson, R.1
-
76
-
-
84874614275
-
NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression
-
Zhang,Q., Chen,C.Y., Yedavalli,V.S. and Jeang,K.T. (2013) NEAT1 long noncoding RNA and paraspeckle bodies modulate HIV-1 posttranscriptional expression. Mbio, 4, e0059612.
-
(2013)
Mbio
, vol.4
-
-
Zhang, Q.1
Chen, C.Y.2
Yedavalli, V.S.3
Jeang, K.T.4
-
77
-
-
84899993786
-
Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth
-
Michalik,K.M., You,X., Manavski,Y., Doddaballapur,A., Zornig,M., Braun,T., John,D., Ponomareva,Y., Chen,W., Uchida,S. et al. (2014) Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth. Circ. Res., 114, 1389-1397.
-
(2014)
Circ. Res.
, vol.114
, pp. 1389-1397
-
-
Michalik, K.M.1
You, X.2
Manavski, Y.3
Doddaballapur, A.4
Zornig, M.5
Braun, T.6
John, D.7
Ponomareva, Y.8
Chen, W.9
Uchida, S.10
-
78
-
-
0042622519
-
Characterization of expression at the human XIST locus in somatic, embryonal carcinoma, and transgenic cell lines
-
Chow,J.C., Hall,L.L., Clemson,C.M., Lawrence,J.B. and Brown,C.J. (2003) Characterization of expression at the human XIST locus in somatic, embryonal carcinoma, and transgenic cell lines. Genomics, 82, 309-322.
-
(2003)
Genomics
, vol.82
, pp. 309-322
-
-
Chow, J.C.1
Hall, L.L.2
Clemson, C.M.3
Lawrence, J.B.4
Brown, C.J.5
-
79
-
-
79951580425
-
Control of RNA processing by a large non-coding RNA over-expressed in carcinomas
-
Lin,R., Roychowdhury-Saha,M., Black,C., Watt,A.T., Marcusson,E.G., Freier,S.M. and Edgington,T.S. (2011) Control of RNA processing by a large non-coding RNA over-expressed in carcinomas. FEBS Lett., 585, 671-676.
-
(2011)
FEBS Lett.
, vol.585
, pp. 671-676
-
-
Lin, R.1
Roychowdhury-Saha, M.2
Black, C.3
Watt, A.T.4
Marcusson, E.G.5
Freier, S.M.6
Edgington, T.S.7
-
80
-
-
84863116597
-
Suppression of progenitor differentiation requires the long noncoding RNA ANCR
-
Kretz,M., Webster,D.E., Flockhart,R.J., Lee,C.S., Zehnder,A., Lopez-Pajares,V., Qu,K., Zheng,G.X., Chow,J., Kim,G.E. et al. (2012) Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes Dev., 26, 338-343.
-
(2012)
Genes Dev.
, vol.26
, pp. 338-343
-
-
Kretz, M.1
Webster, D.E.2
Flockhart, R.J.3
Lee, C.S.4
Zehnder, A.5
Lopez-Pajares, V.6
Qu, K.7
Zheng, G.X.8
Chow, J.9
Kim, G.E.10
-
81
-
-
84942121908
-
Long non-coding RNA-DANCR in human circulating monocytes: A potential biomarker associated with postmenopausal osteoporosis
-
Tong,X., Gu,P.C., Xu,S.Z. and Lin,X.J. (2015) Long non-coding RNA-DANCR in human circulating monocytes: a potential biomarker associated with postmenopausal osteoporosis. Biosci. Biotechnol. Biochem., 79, 732-737.
-
(2015)
Biosci. Biotechnol. Biochem.
, vol.79
, pp. 732-737
-
-
Tong, X.1
Gu, P.C.2
Xu, S.Z.3
Lin, X.J.4
-
82
-
-
84875496875
-
Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression
-
Zhu,L. and Xu,P.C. (2013) Downregulated LncRNA-ANCR promotes osteoblast differentiation by targeting EZH2 and regulating Runx2 expression. Biochem. Biophys. Res. Commun., 432, 612-617.
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.432
, pp. 612-617
-
-
Zhu, L.1
Xu, P.C.2
-
83
-
-
84455206362
-
Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution
-
Ulitsky,I., Shkumatava,A., Jan,C.H., Sive,H. and Bartel,D.P. (2011) Conserved function of lincRNAs in vertebrate embryonic development despite rapid sequence evolution. Cell, 147, 1537-1550.
-
(2011)
Cell
, vol.147
, pp. 1537-1550
-
-
Ulitsky, I.1
Shkumatava, A.2
Jan, C.H.3
Sive, H.4
Bartel, D.P.5
-
84
-
-
67650921949
-
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression
-
Khalil,A.M., Guttman,M., Huarte,M., Garber,M., Raj,A., Rivea Morales,D., Thomas,K., Presser,A., Bernstein,B.E., van Oudenaarden,A. et al. (2009) Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc. Natl. Acad. Sci. U.S.A., 106, 11667-11672.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 11667-11672
-
-
Khalil, A.M.1
Guttman, M.2
Huarte, M.3
Garber, M.4
Raj, A.5
Rivea Morales, D.6
Thomas, K.7
Presser, A.8
Bernstein, B.E.9
Van Oudenaarden, A.10
-
85
-
-
81055140863
-
NcRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs
-
Yang,L., Lin,C., Liu,W., Zhang,J., Ohgi,K.A., Grinstein,J.D., Dorrestein,P.C. and Rosenfeld,M.G. (2011) ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell, 147, 773-788.
-
(2011)
Cell
, vol.147
, pp. 773-788
-
-
Yang, L.1
Lin, C.2
Liu, W.3
Zhang, J.4
Ohgi, K.A.5
Grinstein, J.D.6
Dorrestein, P.C.7
Rosenfeld, M.G.8
-
86
-
-
15744387853
-
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina
-
Young,T.L., Matsuda,T. and Cepko,C.L. (2005) The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr. Biol., 15, 501-512.
-
(2005)
Curr. Biol.
, vol.15
, pp. 501-512
-
-
Young, T.L.1
Matsuda, T.2
Cepko, C.L.3
-
87
-
-
84875248673
-
Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder
-
Han,Y., Liu,Y., Gui,Y. and Cai,Z. (2013) Long intergenic non-coding RNA TUG1 is overexpressed in urothelial carcinoma of the bladder. J. Surg. Oncol., 107, 555-559.
-
(2013)
J. Surg. Oncol.
, vol.107
, pp. 555-559
-
-
Han, Y.1
Liu, Y.2
Gui, Y.3
Cai, Z.4
-
88
-
-
34250729138
-
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
-
Rinn,J.L., Kertesz,M., Wang,J.K., Squazzo,S.L., Xu,X., Brugmann,S.A., Goodnough,L.H., Helms,J.A., Farnham,P.J., Segal,E. et al. (2007) Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell, 129, 1311-1323.
-
(2007)
Cell
, vol.129
, pp. 1311-1323
-
-
Rinn, J.L.1
Kertesz, M.2
Wang, J.K.3
Squazzo, S.L.4
Xu, X.5
Brugmann, S.A.6
Goodnough, L.H.7
Helms, J.A.8
Farnham, P.J.9
Segal, E.10
-
89
-
-
77954572735
-
Long noncoding RNA as modular scaffold of histone modification complexes
-
Tsai,M.C., Manor,O., Wan,Y., Mosammaparast,N., Wang,J.K., Lan,F., Shi,Y., Segal,E. and Chang,H.Y. (2010) Long noncoding RNA as modular scaffold of histone modification complexes. Science, 329, 689-693.
-
(2010)
Science
, vol.329
, pp. 689-693
-
-
Tsai, M.C.1
Manor, O.2
Wan, Y.3
Mosammaparast, N.4
Wang, J.K.5
Lan, F.6
Shi, Y.7
Segal, E.8
Chang, H.Y.9
-
90
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
Gupta,R.A., Shah,N., Wang,K.C., Kim,J., Horlings,H.M., Wong,D.J.,Tsai,M.C., Hung,T., Argani,P., Rinn,J.L. et al. (2010) Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature, 464, 1071-1076.
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
Tsai, M.C.7
Hung, T.8
Argani, P.9
Rinn, J.L.10
-
91
-
-
79955836034
-
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation
-
Yang,Z., Zhou,L., Wu,L.M., Lai,M.C., Xie,H.Y., Zhang,F. and Zheng,S.S. (2011) Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann. Surg. Oncol., 18, 1243-1250.
-
(2011)
Ann. Surg. Oncol.
, vol.18
, pp. 1243-1250
-
-
Yang, Z.1
Zhou, L.2
Wu, L.M.3
Lai, M.C.4
Xie, H.Y.5
Zhang, F.6
Zheng, S.S.7
-
92
-
-
80054029971
-
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers
-
Kogo,R., Shimamura,T., Mimori,K., Kawahara,K., Imoto,S., Sudo,T., Tanaka,F., Shibata,K., Suzuki,A., Komune,S. et al. (2011) Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res., 71, 6320-6326.
-
(2011)
Cancer Res.
, vol.71
, pp. 6320-6326
-
-
Kogo, R.1
Shimamura, T.2
Mimori, K.3
Kawahara, K.4
Imoto, S.5
Sudo, T.6
Tanaka, F.7
Shibata, K.8
Suzuki, A.9
Komune, S.10
-
93
-
-
84886304944
-
Upregulation of the long non-coding RNA HOTAIR promotes esophageal squamous cell carcinoma metastasis and poor prognosis
-
Chen,F.J., Sun,M., Li,S.Q., Wu,Q.Q., Ji,L., Liu,Z.L., Zhou,G.Z., Cao,G., Jin,L., Xie,H.W. et al. (2013) Upregulation of the long non-coding RNA HOTAIR promotes esophageal squamous cell carcinoma metastasis and poor prognosis. Mol. Carcinog., 52, 908-915.
-
(2013)
Mol. Carcinog.
, vol.52
, pp. 908-915
-
-
Chen, F.J.1
Sun, M.2
Li, S.Q.3
Wu, Q.Q.4
Ji, L.5
Liu, Z.L.6
Zhou, G.Z.7
Cao, G.8
Jin, L.9
Xie, H.W.10
-
94
-
-
84885919211
-
Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma
-
Li,X., Wu,Z., Mei,Q., Guo,M., Fu,X. and Han,W. (2013) Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma. Br.J.Cancer, 109, 2266-2278.
-
(2013)
Br.J.Cancer
, vol.109
, pp. 2266-2278
-
-
Li, X.1
Wu, Z.2
Mei, Q.3
Guo, M.4
Fu, X.5
Han, W.6
-
95
-
-
84883762956
-
Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol
-
Bhan,A., Hussain,I., Ansari,K.I., Kasiri,S., Bashyal,A. and Mandal,S.S. (2013) Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol. J. Mol. Biol., 425, 3707-3722.
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 3707-3722
-
-
Bhan, A.1
Hussain, I.2
Ansari, K.I.3
Kasiri, S.4
Bashyal, A.5
Mandal, S.S.6
-
96
-
-
84875890253
-
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer
-
Kim,K., Jutooru,I., Chadalapaka,G., Johnson,G., Frank,J., Burghardt,R., Kim,S. and Safe,S. (2013) HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene, 32, 1616-1625.
-
(2013)
Oncogene
, vol.32
, pp. 1616-1625
-
-
Kim, K.1
Jutooru, I.2
Chadalapaka, G.3
Johnson, G.4
Frank, J.5
Burghardt, R.6
Kim, S.7
Safe, S.8
-
97
-
-
84899754537
-
Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells
-
Chiyomaru,T., Fukuhara,S., Saini,S., Majid,S., Deng,G., Shahryari,V., Chang,I., Tanaka,Y., Enokida,H., Nakagawa,M. et al. (2014) Long non-coding RNA HOTAIR is targeted and regulated by miR-141 in human cancer cells. J. Biol. Chem., 289, 12550-12565.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 12550-12565
-
-
Chiyomaru, T.1
Fukuhara, S.2
Saini, S.3
Majid, S.4
Deng, G.5
Shahryari, V.6
Chang, I.7
Tanaka, Y.8
Enokida, H.9
Nakagawa, M.10
-
98
-
-
84890262848
-
EZH2 takes the stage when BRCA1 loses
-
Wang,L. and Huang,H. (2013) EZH2 takes the stage when BRCA1 loses. Cell Cycle, 12, 3575-3576.
-
(2013)
Cell Cycle
, vol.12
, pp. 3575-3576
-
-
Wang, L.1
Huang, H.2
-
99
-
-
34548548614
-
Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
-
Castanotto,D., Sakurai,K., Lingeman,R., Li,H., Shively,L., Aagaard,L., Soifer,H., Gatignol,A., Riggs,A. and Rossi,J.J. (2007) Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC. Nucleic Acids Res., 35, 5154-5164.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 5154-5164
-
-
Castanotto, D.1
Sakurai, K.2
Lingeman, R.3
Li, H.4
Shively, L.5
Aagaard, L.6
Soifer, H.7
Gatignol, A.8
Riggs, A.9
Rossi, J.J.10
-
100
-
-
36148972467
-
Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells
-
Vickers,T.A., Lima,W.F., Nichols,J.G. and Crooke,S.T. (2007) Reduced levels of Ago2 expression result in increased siRNA competition in mammalian cells. Nucleic Acids Res., 35, 6598-6610.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 6598-6610
-
-
Vickers, T.A.1
Lima, W.F.2
Nichols, J.G.3
Crooke, S.T.4
-
101
-
-
24144445346
-
Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells
-
Miyagishi,M., Hayashi,M. and Taira,K. (2003) Comparison of the suppressive effects of antisense oligonucleotides and siRNAs directed against the same targets in mammalian cells. Antisense Nucleic Acid Drug. Dev., 13, 1-7.
-
(2003)
Antisense Nucleic Acid Drug. Dev.
, vol.13
, pp. 1-7
-
-
Miyagishi, M.1
Hayashi, M.2
Taira, K.3
-
102
-
-
0042161890
-
The activity of siRNA in mammalian cells is related to structural target accessibility: A comparison with antisense oligonucleotides
-
Kretschmer-Kazemi Far,R. and Sczakiel,G. (2003) The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides. Nucleic Acids Res., 31, 4417-4424.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4417-4424
-
-
Kretschmer-Kazemi Far, R.1
Sczakiel, G.2
-
103
-
-
0038578021
-
Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′-O-methyl RNA, phosphorothioates and small interfering RNA
-
Grunweller,A., Wyszko,E., Bieber,B., Jahnel,R., Erdmann,V.A. and Kurreck,J. (2003) Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2′-O-methyl RNA, phosphorothioates and small interfering RNA. Nucleic Acids Res., 31, 3185-3193.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3185-3193
-
-
Grunweller, A.1
Wyszko, E.2
Bieber, B.3
Jahnel, R.4
Erdmann, V.A.5
Kurreck, J.6
-
104
-
-
63449124025
-
Increased potency and longevity of gene silencing using validated Dicer substrates
-
Hefner,E., Clark,K., Whitman,C., Behlke,M.A., Rose,S.D., Peek,A.S. and Rubio,T. (2008) Increased potency and longevity of gene silencing using validated Dicer substrates. J. Biomol. Tech., 19, 231-237.
-
(2008)
J. Biomol. Tech.
, vol.19
, pp. 231-237
-
-
Hefner, E.1
Clark, K.2
Whitman, C.3
Behlke, M.A.4
Rose, S.D.5
Peek, A.S.6
Rubio, T.7
-
105
-
-
84857375929
-
Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
-
Foster,D.J., Barros,S., Duncan,R., Shaikh,S., Cantley,W., Dell,A., Bulgakova,E., O'Shea,J., Taneja,N., Kuchimanchi,S. et al. (2012) Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo. RNA, 18, 557-568.
-
(2012)
RNA
, vol.18
, pp. 557-568
-
-
Foster, D.J.1
Barros, S.2
Duncan, R.3
Shaikh, S.4
Cantley, W.5
Dell, A.6
Bulgakova, E.7
O'Shea, J.8
Taneja, N.9
Kuchimanchi, S.10
-
106
-
-
84891831905
-
Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo
-
Dudek,H., Wong,D.H., Arvan,R., Shah,A., Wortham,K., Ying,B., Diwanji,R., Zhou,W., Holmes,B., Yang,H. et al. (2014) Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo. Mol. Ther., 22, 92-101.
-
(2014)
Mol. Ther.
, vol.22
, pp. 92-101
-
-
Dudek, H.1
Wong, D.H.2
Arvan, R.3
Shah, A.4
Wortham, K.5
Ying, B.6
Diwanji, R.7
Zhou, W.8
Holmes, B.9
Yang, H.10
-
107
-
-
33846902312
-
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals
-
Swayze,E.E., Siwkowski,A.M., Wancewicz,E.V., Migawa,M.T., Wyrzykiewicz,T.K., Hung,G., Monia,B.P. and Bennett,C.F. (2007) Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals. Nucleic Acids Res., 35, 687-700.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 687-700
-
-
Swayze, E.E.1
Siwkowski, A.M.2
Wancewicz, E.V.3
Migawa, M.T.4
Wyrzykiewicz, T.K.5
Hung, G.6
Monia, B.P.7
Bennett, C.F.8
-
108
-
-
84883404077
-
Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern
-
Hagedorn,P.H., Yakimov,V., Ottosen,S., Kammler,S., Nielsen,N.F., Hog,A.M., Hedtjarn,M., Meldgaard,M., Moller,M.R., Orum,H. et al. (2013) Hepatotoxic potential of therapeutic oligonucleotides can be predicted from their sequence and modification pattern. Nucleic Acid Ther., 23, 302-310.
-
(2013)
Nucleic Acid Ther.
, vol.23
, pp. 302-310
-
-
Hagedorn, P.H.1
Yakimov, V.2
Ottosen, S.3
Kammler, S.4
Nielsen, N.F.5
Hog, A.M.6
Hedtjarn, M.7
Meldgaard, M.8
Moller, M.R.9
Orum, H.10
-
109
-
-
34247272091
-
Design of active small interfering RNAs
-
Peek,A.S. and Behlke,M.A. (2007) Design of active small interfering RNAs. Curr. Opin. Mol. Ther., 9, 110-118.
-
(2007)
Curr. Opin. Mol. Ther.
, vol.9
, pp. 110-118
-
-
Peek, A.S.1
Behlke, M.A.2
-
110
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds,A., Leake,D., Boese,Q., Scaringe,S., Marshall,W.S. and Khvorova,A. (2004) Rational siRNA design for RNA interference. Nat. Biotechnol., 22, 326-330.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
111
-
-
38449100230
-
A protocol for designing siRNAs with high functionality and specificity
-
Birmingham,A., Anderson,E., Sullivan,K., Reynolds,A., Boese,Q., Leake,D., Karpilow,J. and Khvorova,A. (2007) A protocol for designing siRNAs with high functionality and specificity. Nat. Protoc., 2, 2068-2078.
-
(2007)
Nat. Protoc.
, vol.2
, pp. 2068-2078
-
-
Birmingham, A.1
Anderson, E.2
Sullivan, K.3
Reynolds, A.4
Boese, Q.5
Leake, D.6
Karpilow, J.7
Khvorova, A.8
-
112
-
-
75649110049
-
Selection of hyperfunctional siRNAs with improved potency and specificity
-
Wang,X., Varma,R.K., Beauchamp,L., Magdaleno,S. and Sendera,T.J. (2009) Selection of hyperfunctional siRNAs with improved potency and specificity. Nucleic Acids Res., 37, e152.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. e152
-
-
Wang, X.1
Varma, R.K.2
Beauchamp, L.3
Magdaleno, S.4
Sendera, T.J.5
-
113
-
-
0041630618
-
Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs
-
Xu,Y., Zhang,H.Y., Thormeyer,D., Larsson,O., Du,Q., Elmen,J., Wahlestedt,C. and Liang,Z. (2003) Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochem. Biophys. Res. Commun., 306, 712-717.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.306
, pp. 712-717
-
-
Xu, Y.1
Zhang, H.Y.2
Thormeyer, D.3
Larsson, O.4
Du, Q.5
Elmen, J.6
Wahlestedt, C.7
Liang, Z.8
-
114
-
-
84946543730
-
Identification and characterization of modified antisense oligonucleotides targeting dmpk in mice and nonhuman primates for the treatment of myotonic dystrophy type 1
-
Pandey,S.K., Wheeler,T.M., Justice,S.L., Kim,A., Younis,H.S., Gattis,D., Jauvin,D., Puymirat,J., Swayze,E.E., Freier,S.M. et al. (2015) Identification and characterization of modified antisense oligonucleotides targeting dmpk in mice and nonhuman primates for the treatment of myotonic dystrophy type 1. J. Pharmacol. Exp. Ther., 355, 310-321.
-
(2015)
J. Pharmacol. Exp. Ther.
, vol.355
, pp. 310-321
-
-
Pandey, S.K.1
Wheeler, T.M.2
Justice, S.L.3
Kim, A.4
Younis, H.S.5
Gattis, D.6
Jauvin, D.7
Puymirat, J.8
Swayze, E.E.9
Freier, S.M.10
-
115
-
-
84966345573
-
The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA
-
Vickers,T.A. and Crooke,S.T. (2015) The rates of the major steps in the molecular mechanism of RNase H1-dependent antisense oligonucleotide induced degradation of RNA. Nucleic Acids Res., 43, 8955-8963.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 8955-8963
-
-
Vickers, T.A.1
Crooke, S.T.2
-
116
-
-
80955175388
-
The importance of RT-qPCR primer design for the detection of siRNA-mediated mRNA silencing
-
Herbert,M., Coppieters,N., Lasham,A., Cao,H. and Reid,G. (2011) The importance of RT-qPCR primer design for the detection of siRNA-mediated mRNA silencing. BMC Res. Notes, 4, e148.
-
(2011)
BMC Res. Notes
, vol.4
, pp. e148
-
-
Herbert, M.1
Coppieters, N.2
Lasham, A.3
Cao, H.4
Reid, G.5
-
117
-
-
13744258255
-
Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides
-
Hasselblatt,P., Hockenjos,B., Thoma,C., Blum,H.E. and Offensperger,W.B. (2005) Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides. Nucleic Acids Res., 33, 114-125.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 114-125
-
-
Hasselblatt, P.1
Hockenjos, B.2
Thoma, C.3
Blum, H.E.4
Offensperger, W.B.5
|