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Volumn 44, Issue 7, 2015, Pages 3131-3146

A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B PROTEIN; PROTEIN TDP1; UNCLASSIFIED DRUG; VARIANT SURFACE GLYCOPROTEIN; CHROMATIN; HIGH MOBILITY GROUP PROTEIN;

EID: 84965166232     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv1459     Document Type: Article
Times cited : (27)

References (56)
  • 1
    • 0033229970 scopus 로고    scopus 로고
    • The economics of ribosome biosynthesis in yeast
    • Warner, J.R. (1999) The economics of ribosome biosynthesis in yeast. Trends Biochem. Sci., 24, 437-440.
    • (1999) Trends Biochem. Sci , vol.24 , pp. 437-440
    • Warner, J.R.1
  • 2
    • 55849109584 scopus 로고    scopus 로고
    • The epigenetics of rRNA genes: From molecular to chromosome biology
    • McStay, B., Grummt, I. (2008) The epigenetics of rRNA genes: from molecular to chromosome biology. Annu. Rev. Cell Dev. Biol., 24, 131-157.
    • (2008) Annu. Rev. Cell Dev. Biol , vol.24 , pp. 131-157
    • McStay, B.1    Grummt, I.2
  • 4
    • 67649397588 scopus 로고    scopus 로고
    • Epigenetic regulation in African trypanosomes: A new kid on the block
    • Figueiredo, L.M., Cross, G.A., Janzen, C.J. (2009) Epigenetic regulation in African trypanosomes: a new kid on the block. Nat. Rev. Microbiol., 7, 504-513.
    • (2009) Nat. Rev. Microbiol , vol.7 , pp. 504-513
    • Figueiredo, L.M.1    Cross, G.A.2    Janzen, C.J.3
  • 5
    • 18844462890 scopus 로고    scopus 로고
    • RNA polymerase i transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei
    • Gunzl, A., Bruderer, T., Laufer, G., Schimanski, B., Tu, L.C., Chung, H.M., Lee, P.T., Lee, M.G. (2003) RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot. Cell, 2, 542-551.
    • (2003) Eukaryot. Cell , vol.2 , pp. 542-551
    • Gunzl, A.1    Bruderer, T.2    Laufer, G.3    Schimanski, B.4    Tu, L.C.5    Chung, H.M.6    Lee, P.T.7    Lee, M.G.8
  • 6
    • 84905324241 scopus 로고    scopus 로고
    • Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427
    • Cross, G.A., Kim, H.S., Wickstead, B. (2014) Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427. Mol. Biochem. Parasitol., 195, 59-73.
    • (2014) Mol. Biochem. Parasitol , vol.195 , pp. 59-73
    • Cross, G.A.1    Kim, H.S.2    Wickstead, B.3
  • 8
    • 78649657053 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the control of antigenic variation in African trypanosomes
    • Horn, D., McCulloch, R. (2010) Molecular mechanisms underlying the control of antigenic variation in African trypanosomes. Curr. Opin. Microbiol., 13, 700-705.
    • (2010) Curr. Opin. Microbiol , vol.13 , pp. 700-705
    • Horn, D.1    McCulloch, R.2
  • 9
    • 0033199568 scopus 로고    scopus 로고
    • Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei
    • Chaves, I., Rudenko, G., Dirks-Mulder, A., Cross, M., Borst, P. (1999) Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei. EMBO J., 18, 4846-4855.
    • (1999) EMBO J , vol.18 , pp. 4846-4855
    • Chaves, I.1    Rudenko, G.2    Dirks-Mulder, A.3    Cross, M.4    Borst, P.5
  • 10
    • 0030911625 scopus 로고    scopus 로고
    • Manipulation of the vsg co-transposed region increases expression-site switching in Trypanosoma brucei
    • Davies, K.P., Carruthers, V.B., Cross, G.A. (1997) Manipulation of the vsg co-transposed region increases expression-site switching in Trypanosoma brucei. Mol .Biochem. Parasitol., 86, 163-177.
    • (1997) Mol .Biochem. Parasitol , vol.86 , pp. 163-177
    • Davies, K.P.1    Carruthers, V.B.2    Cross, G.A.3
  • 11
    • 84901322899 scopus 로고    scopus 로고
    • Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei
    • Batram, C., Jones, N.G., Janzen, C.J., Markert, S.M., Engstler, M. (2014) Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei. Elife (Cambridge), 3, e02324.
    • (2014) Elife (Cambridge) , vol.3 , pp. e02324
    • Batram, C.1    Jones, N.G.2    Janzen, C.J.3    Markert, S.M.4    Engstler, M.5
  • 12
    • 75649110809 scopus 로고    scopus 로고
    • Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase i in African trypanosomes
    • Figueiredo, L.M., Cross, G.A. (2010) Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot. Cell, 9, 148-154.
    • (2010) Eukaryot. Cell , vol.9 , pp. 148-154
    • Figueiredo, L.M.1    Cross, G.A.2
  • 13
    • 75649140875 scopus 로고    scopus 로고
    • Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes
    • Stanne, T.M., Rudenko, G. (2010) Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes. Eukaryot. Cell, 9, 136-147.
    • (2010) Eukaryot. Cell , vol.9 , pp. 136-147
    • Stanne, T.M.1    Rudenko, G.2
  • 15
    • 84898942049 scopus 로고    scopus 로고
    • Promoter occupancy of the basal class i transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei
    • Nguyen, T.N., Muller, L.S., Park, S.H., Siegel, T.N., Gunzl, A. (2014) Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei. Nucleic Acids Res., 42, 3164-3176.
    • (2014) Nucleic Acids Res , vol.42 , pp. 3164-3176
    • Nguyen, T.N.1    Muller, L.S.2    Park, S.H.3    Siegel, T.N.4    Gunzl, A.5
  • 16
    • 84922729767 scopus 로고    scopus 로고
    • Mono-allelic VSG expression by RNA polymerase i in Trypanosoma brucei: Expression site control from both ends
    • Gunzl, A., Kirkham, J.K., Nguyen, T.N., Badjatia, N., Park, S.H. (2015) Mono-allelic VSG expression by RNA polymerase I in Trypanosoma brucei: Expression site control from both ends? Gene, 556, 68-73.
    • (2015) Gene , vol.556 , pp. 68-73
    • Gunzl, A.1    Kirkham, J.K.2    Nguyen, T.N.3    Badjatia, N.4    Park, S.H.5
  • 17
    • 48349107004 scopus 로고    scopus 로고
    • A histone methyltransferase modulates antigenic variation in African trypanosomes
    • Figueiredo, L.M., Janzen, C.J., Cross, G.A. (2008) A histone methyltransferase modulates antigenic variation in African trypanosomes. PLoS Biol., 6, e161.
    • (2008) PLoS Biol , vol.6 , pp. e161
    • Figueiredo, L.M.1    Janzen, C.J.2    Cross, G.A.3
  • 18
    • 84876391617 scopus 로고    scopus 로고
    • TDP1 is an HMG chromatin protein facilitating RNA polymerase i transcription in African trypanosomes
    • Narayanan, M.S., Rudenko, G. (2013) TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes. Nucleic Acids Res., 41, 2981-2992.
    • (2013) Nucleic Acids Res , vol.41 , pp. 2981-2992
    • Narayanan, M.S.1    Rudenko, G.2
  • 19
    • 0026537593 scopus 로고
    • Differential expression of 2 messenger-rnas from a single gene encoding an hmg1-like DNA-Binding protein of african trypanosomes
    • Erondu, N.E., Donelson, J.E. (1992) Differential Expression of 2 Messenger-Rnas from a Single Gene Encoding an Hmg1-Like DNA-Binding Protein of African Trypanosomes. Mol. Biochem. Parasitol., 51, 111-118.
    • (1992) Mol. Biochem. Parasitol , vol.51 , pp. 111-118
    • Erondu, N.E.1    Donelson, J.E.2
  • 20
    • 36549074152 scopus 로고    scopus 로고
    • The cell biology of Trypanosoma brucei differentiation
    • Fenn, K., Matthews, K.R. (2007) The cell biology of Trypanosoma brucei differentiation. Curr. Opin. Microbiol., 10, 539-546.
    • (2007) Curr. Opin. Microbiol , vol.10 , pp. 539-546
    • Fenn, K.1    Matthews, K.R.2
  • 21
    • 0025034288 scopus 로고
    • Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro
    • Ziegelbauer, K., Quinten, M., Schwarz, H., Pearson, T.W., Overath, P. (1990) Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro. Eur. J. Biochem., 192, 373-378.
    • (1990) Eur. J. Biochem , vol.192 , pp. 373-378
    • Ziegelbauer, K.1    Quinten, M.2    Schwarz, H.3    Pearson, T.W.4    Overath, P.5
  • 22
    • 1642483811 scopus 로고    scopus 로고
    • Loss of the mono-allelic control of the VSG expression sites during the development of Trypanosoma brucei in the bloodstream
    • Amiguet-Vercher, A., Perez-Morga, D., Pays, A., Poelvoorde, P., Xong, H., Tebabi, P., Vanhamme, L., Pays, E. (2004) Loss of the mono-allelic control of the VSG expression sites during the development of Trypanosoma brucei in the bloodstream. Mol. Microbiol., 51, 1577-1588.
    • (2004) Mol. Microbiol , vol.51 , pp. 1577-1588
    • Amiguet-Vercher, A.1    Perez-Morga, D.2    Pays, A.3    Poelvoorde, P.4    Xong, H.5    Tebabi, P.6    Vanhamme, L.7    Pays, E.8
  • 23
    • 33846406103 scopus 로고    scopus 로고
    • Nuclear repositioning of the VSG promoter during developmental silencing in Trypanosoma brucei
    • Landeira, D., Navarro, M. (2007) Nuclear repositioning of the VSG promoter during developmental silencing in Trypanosoma brucei. J. Cell Biol., 176, 133-139.
    • (2007) J. Cell Biol , vol.176 , pp. 133-139
    • Landeira, D.1    Navarro, M.2
  • 24
    • 0033561049 scopus 로고    scopus 로고
    • Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites
    • Navarro, M., Cross, G.A., Wirtz, E. (1999) Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites. EMBO J., 18, 2265-2272.
    • (1999) EMBO J , vol.18 , pp. 2265-2272
    • Navarro, M.1    Cross, G.A.2    Wirtz, E.3
  • 25
    • 0016809286 scopus 로고
    • Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei
    • Cross, G.A. (1975) Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat of Trypanosoma brucei. Parasitology, 71, 393-417.
    • (1975) Parasitology , vol.71 , pp. 393-417
    • Cross, G.A.1
  • 26
    • 0024948840 scopus 로고
    • Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers
    • Hirumi, H., Hirumi, K. (1989) Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. J. Parasitol., 75, 985-989.
    • (1989) J. Parasitol , vol.75 , pp. 985-989
    • Hirumi, H.1    Hirumi, K.2
  • 27
    • 63049115947 scopus 로고    scopus 로고
    • RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei
    • Yang, X., Figueiredo, L.M., Espinal, A., Okubo, E., Li, B. (2009) RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei. Cell, 137, 99-109.
    • (2009) Cell , vol.137 , pp. 99-109
    • Yang, X.1    Figueiredo, L.M.2    Espinal, A.3    Okubo, E.4    Li, B.5
  • 28
    • 78049436362 scopus 로고    scopus 로고
    • Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters
    • Schumann Burkard, G., Jutzi, P., Roditi, I. (2011) Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters. Mol. Biochem. Parasitol., 175, 91-94.
    • (2011) Mol. Biochem. Parasitol , vol.175 , pp. 91-94
    • Schumann Burkard, G.1    Jutzi, P.2    Roditi, I.3
  • 29
    • 77956133527 scopus 로고    scopus 로고
    • Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes
    • Wang, Q.P., Kawahara, T., Horn, D. (2010) Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes. Mol. Microbiol., 77, 1237-1245.
    • (2010) Mol. Microbiol , vol.77 , pp. 1237-1245
    • Wang, Q.P.1    Kawahara, T.2    Horn, D.3
  • 32
    • 0029894292 scopus 로고    scopus 로고
    • A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei
    • Bastin, P., Bagherzadeh, Z., Matthews, K.R., Gull, K. (1996) A novel epitope tag system to study protein targeting and organelle biogenesis in Trypanosoma brucei. Mol. Biochem. Parasitol., 77, 235-239.
    • (1996) Mol. Biochem. Parasitol , vol.77 , pp. 235-239
    • Bastin, P.1    Bagherzadeh, Z.2    Matthews, K.R.3    Gull, K.4
  • 33
    • 81055139232 scopus 로고    scopus 로고
    • Transcription by the multifunctional RNA polymerase i in Trypanosoma brucei functions independently of RPB7
    • Park, S.H., Nguyen, T.N., Kirkham, J.K., Lee, J.H., Gunzl, A. (2011) Transcription by the multifunctional RNA polymerase I in Trypanosoma brucei functions independently of RPB7. Mol. Biochem. Parasitol., 180, 35-42.
    • (2011) Mol. Biochem. Parasitol , vol.180 , pp. 35-42
    • Park, S.H.1    Nguyen, T.N.2    Kirkham, J.K.3    Lee, J.H.4    Gunzl, A.5
  • 34
    • 0021971721 scopus 로고
    • Use of monoclonal antibodies to analyse the expression of a multi-tubulin family
    • Birkett, C.R., Foster, K.E., Johnson, L., Gull, K. (1985) Use of monoclonal antibodies to analyse the expression of a multi-tubulin family. FEBS Lett., 187, 211-218.
    • (1985) FEBS Lett , vol.187 , pp. 211-218
    • Birkett, C.R.1    Foster, K.E.2    Johnson, L.3    Gull, K.4
  • 35
  • 36
    • 70549084861 scopus 로고    scopus 로고
    • Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons
    • Queiroz, R., Benz, C., Fellenberg, K., Hoheisel, J.D., Clayton, C. (2009) Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons. BMC Genomics, 10, 495.
    • (2009) BMC Genomics , vol.10 , pp. 495
    • Queiroz, R.1    Benz, C.2    Fellenberg, K.3    Hoheisel, J.D.4    Clayton, C.5
  • 37
    • 34250369627 scopus 로고    scopus 로고
    • FAIRE (Formaldehyde-Assisted isolation of regulatory elements) isolates active regulatory elements from human chromatin
    • Giresi, P.G., Kim, J., McDaniell, R.M., Iyer, V.R., Lieb, J.D. (2007) FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) isolates active regulatory elements from human chromatin. Genome Res., 17, 877-885.
    • (2007) Genome Res , vol.17 , pp. 877-885
    • Giresi, P.G.1    Kim, J.2    McDaniell, R.M.3    Iyer, V.R.4    Lieb, J.D.5
  • 38
    • 77955299108 scopus 로고    scopus 로고
    • Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei
    • Worthen, C., Jensen, B.C., Parsons, M. (2010) Diverse effects on mitochondrial and nuclear functions elicited by drugs and genetic knockdowns in bloodstream stage Trypanosoma brucei. PLoS Negl. Trop. Dis., 4, e678.
    • (2010) PLoS Negl. Trop. Dis , vol.4 , pp. e678
    • Worthen, C.1    Jensen, B.C.2    Parsons, M.3
  • 39
    • 70449560425 scopus 로고    scopus 로고
    • Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei
    • Patrick, K.L., Shi, H., Kolev, N.G., Ersfeld, K., Tschudi, C., Ullu, E. (2009) Distinct and overlapping roles for two Dicer-like proteins in the RNA interference pathways of the ancient eukaryote Trypanosoma brucei. Proc. Natl. Acad. Sci. U.S.A., 106, 17933-17938.
    • (2009) Proc. Natl. Acad. Sci. U.S.A , vol.106 , pp. 17933-17938
    • Patrick, K.L.1    Shi, H.2    Kolev, N.G.3    Ersfeld, K.4    Tschudi, C.5    Ullu, E.6
  • 40
    • 0034106940 scopus 로고    scopus 로고
    • Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei
    • Vanhamme, L., Poelvoorde, P., Pays, A., Tebabi, P., Van Xong, H., Pays, E. (2000) Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei. Mol. Microbiol., 36, 328-340.
    • (2000) Mol. Microbiol , vol.36 , pp. 328-340
    • Vanhamme, L.1    Poelvoorde, P.2    Pays, A.3    Tebabi, P.4    Van Xong, H.5    Pays, E.6
  • 41
    • 84902579069 scopus 로고    scopus 로고
    • Transcription is initiated on silent variant surface glycoprotein expression sites despite monoallelic expression in Trypanosoma brucei
    • Kassem, A., Pays, E., Vanhamme, L. (2014) Transcription is initiated on silent variant surface glycoprotein expression sites despite monoallelic expression in Trypanosoma brucei. Proc. Natl. Acad. Sci. U.S.A., 111, 8943-8948.
    • (2014) Proc. Natl. Acad. Sci. U.S.A , vol.111 , pp. 8943-8948
    • Kassem, A.1    Pays, E.2    Vanhamme, L.3
  • 42
    • 67749090919 scopus 로고    scopus 로고
    • Cohesin regulates VSG monoallelic expression in trypanosomes
    • Landeira, D., Bart, J.M., Van Tyne, D., Navarro, M. (2009) Cohesin regulates VSG monoallelic expression in trypanosomes. J. Cell Biol., 186, 243-254.
    • (2009) J. Cell Biol , vol.186 , pp. 243-254
    • Landeira, D.1    Bart, J.M.2    Van Tyne, D.3    Navarro, M.4
  • 43
    • 74549187994 scopus 로고    scopus 로고
    • Nuclear functions of the HMG proteins
    • Reeves, R. (2010) Nuclear functions of the HMG proteins. Biochim. Biophys. Acta, 1799, 3-14.
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 3-14
    • Reeves, R.1
  • 44
    • 74549146153 scopus 로고    scopus 로고
    • HMGB proteins and transcriptional regulation
    • Ueda, T., Yoshida, M. (2010) HMGB proteins and transcriptional regulation. Biochim. Biophys. Acta, 1799, 114-118.
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 114-118
    • Ueda, T.1    Yoshida, M.2
  • 46
    • 0037107455 scopus 로고    scopus 로고
    • Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system
    • Gadal, O., Labarre, S., Boschiero, C., Thuriaux, P. (2002) Hmo1, an HMG-box protein, belongs to the yeast ribosomal DNA transcription system. EMBO J., 21, 5498-5507.
    • (2002) EMBO J , vol.21 , pp. 5498-5507
    • Gadal, O.1    Labarre, S.2    Boschiero, C.3    Thuriaux, P.4
  • 47
    • 74549226503 scopus 로고    scopus 로고
    • HMGB proteins: Interactions with DNA and chromatin
    • Stros, M. (2010) HMGB proteins: interactions with DNA and chromatin. Biochim. Biophys. Acta, 1799, 101-113.
    • (2010) Biochim. Biophys. Acta , vol.1799 , pp. 101-113
    • Stros, M.1
  • 48
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • Groth, A., Rocha, W., Verreault, A., Almouzni, G. (2007) Chromatin challenges during DNA replication and repair. Cell, 128, 721-733.
    • (2007) Cell , vol.128 , pp. 721-733
    • Groth, A.1    Rocha, W.2    Verreault, A.3    Almouzni, G.4
  • 49
    • 77957671534 scopus 로고    scopus 로고
    • A newly discovered role of telomeres in an ancient organism
    • Li, B. (2010) A newly discovered role of telomeres in an ancient organism. Nucleus, 1, 260-263.
    • (2010) Nucleus , vol.1 , pp. 260-263
    • Li, B.1
  • 50
    • 84864321476 scopus 로고    scopus 로고
    • Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei
    • Tiengwe, C., Marcello, L., Farr, H., Dickens, N., Kelly, S., Swiderski, M., Vaughan, D., Gull, K., Barry, J.D., Bell, S.D. et al. (2012) Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Rep., 2, 185-197.
    • (2012) Cell Rep , vol.2 , pp. 185-197
    • Tiengwe, C.1    Marcello, L.2    Farr, H.3    Dickens, N.4    Kelly, S.5    Swiderski, M.6    Vaughan, D.7    Gull, K.8    Barry, J.D.9    Bell, S.D.10
  • 52
    • 84928524398 scopus 로고    scopus 로고
    • High-wire act: The poised genome and cellular memory
    • Puri, D., Gala, H., Mishra, R., Dhawan, J. (2014) High-wire act: the poised genome and cellular memory. FEBS J., 282, 1675-1691.
    • (2014) FEBS J , vol.282 , pp. 1675-1691
    • Puri, D.1    Gala, H.2    Mishra, R.3    Dhawan, J.4
  • 53
    • 84879216186 scopus 로고    scopus 로고
    • Epigenetic regulation of inducible gene expression in the immune system
    • Lim, P.S., Li, J., Holloway, A.F., Rao, S. (2013) Epigenetic regulation of inducible gene expression in the immune system. Immunology, 139, 285-293.
    • (2013) Immunology , vol.139 , pp. 285-293
    • Lim, P.S.1    Li, J.2    Holloway, A.F.3    Rao, S.4
  • 55
    • 0037625160 scopus 로고    scopus 로고
    • Gene segment selection in v D J Recombination: Accessibility and beyond
    • Krangel, M.S. (2003) Gene segment selection in V(D)J recombination: accessibility and beyond. Nat. Immunol., 4, 624-630.
    • (2003) Nat. Immunol , vol.4 , pp. 624-630
    • Krangel, M.S.1
  • 56
    • 70349731776 scopus 로고    scopus 로고
    • Genome-Wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei
    • Kabani, S., Fenn, K., Ross, A., Ivens, A., Smith, T.K., Ghazal, P., Matthews, K. (2009) Genome-wide expression profiling of in vivo-derived bloodstream parasite stages and dynamic analysis of mRNA alterations during synchronous differentiation in Trypanosoma brucei. BMC Genomics, 10, 427.
    • (2009) BMC Genomics , vol.10 , pp. 427
    • Kabani, S.1    Fenn, K.2    Ross, A.3    Ivens, A.4    Smith, T.K.5    Ghazal, P.6    Matthews, K.7


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