Trypanosoma brucei histone H1 inhibits RNA polymerase I transcription and is important for parasite fitness in vivo

Molecular Microbiology

Volumn 93, Issue 4, 2014, Pages 645-663

  Pena, Ana C ^a   Pimentel, Mafalda R ^a   Manso, Helena ^a   Vaz Drago, Rita ^a   Pinto Neves, Daniel ^a   Aresta Branco, Francisco ^a   Rijo Ferreira, Filipa ^a   Guegan, Fabien ^a   Pedro Coelho, Luis ^a,c   Carmo Fonseca, Maria ^a   Barbosa Morais, Nuno L ^a,b   Figueiredo, Luisa M ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 THIOURIDINE; DNA DIRECTED RNA POLYMERASE; HISTONE H1; UNCLASSIFIED DRUG; URIDINE DERIVATIVE; VARIANT SURFACE GLYCOPROTEIN; HISTONE;

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL LABELING; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE LOCUS; GENE SILENCING; HOST PARASITE INTERACTION; IN VIVO STUDY; MOUSE; NONHUMAN; PARASITE DEVELOPMENT; PARASITE VIRULENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROCYCLIN GENE; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; TRANSCRIPTION TERMINATION; VARIANT SURFACE GLYCOPROTEIN GENE; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; GENETICS; HOST PATHOGEN INTERACTION; METABOLISM; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; REGULON; TRYPANOSOMA BRUCEI BRUCEI; VIRULENCE;

MUS; TRYPANOSOMA BRUCEI;

ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HISTONES; HOST-PATHOGEN INTERACTIONS; MICE; REGULON; RNA POLYMERASE I; TRANSCRIPTION, GENETIC; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMIASIS, AFRICAN; VIRULENCE;

EID: 84927788310     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.12677     Document Type: Article

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