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Volumn 556, Issue 1, 2015, Pages 68-73

Mono-allelic VSG expression by RNA polymerase I in Trypanosoma brucei: Expression site control from both ends?

Author keywords

Mono allelic gene expression; RNA polymerase I; Telomeric silencing; Trypanosome

Indexed keywords

DNA DIRECTED RNA POLYMERASE; VARIANT SURFACE GLYCOPROTEIN;

EID: 84922729767     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2014.09.047     Document Type: Article
Times cited : (36)

References (67)
  • 1
    • 84869046968 scopus 로고    scopus 로고
    • Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei
    • Alsford S., Horn D. Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei. Nucleic Acids Res. 2012, 40:10150-10160.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10150-10160
    • Alsford, S.1    Horn, D.2
  • 2
    • 84866153616 scopus 로고    scopus 로고
    • Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes
    • Alsford S., duBois K., Horn D., Field M.C. Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes. Expert. Rev. Mol. Med. 2012, 14:e13.
    • (2012) Expert. Rev. Mol. Med. , vol.14 , pp. e13
    • Alsford, S.1    duBois, K.2    Horn, D.3    Field, M.C.4
  • 3
    • 0033062624 scopus 로고    scopus 로고
    • Transcription of 'inactive' expression sites in African trypanosomes leads to expression of multiple transferrin receptor RNAs in bloodstream forms
    • Ansorge I., Steverding D., Melville S., Hartmann C., Clayton C. Transcription of 'inactive' expression sites in African trypanosomes leads to expression of multiple transferrin receptor RNAs in bloodstream forms. Mol. Biochem. Parasitol. 1999, 101:81-94.
    • (1999) Mol. Biochem. Parasitol. , vol.101 , pp. 81-94
    • Ansorge, I.1    Steverding, D.2    Melville, S.3    Hartmann, C.4    Clayton, C.5
  • 4
    • 84901322899 scopus 로고    scopus 로고
    • Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei
    • Batram C., Jones N.G., Janzen C.J., Markert S.M., Engstler M. Expression site attenuation mechanistically links antigenic variation and development in Trypanosoma brucei. Elife 2014, 3:e02324.
    • (2014) Elife , vol.3 , pp. e02324
    • Batram, C.1    Jones, N.G.2    Janzen, C.J.3    Markert, S.M.4    Engstler, M.5
  • 6
    • 0032576751 scopus 로고    scopus 로고
    • The role of transferrin-receptor variation in the host range of Trypanosoma brucei
    • Bitter W., Gerrits H., Kieft R., Borst P. The role of transferrin-receptor variation in the host range of Trypanosoma brucei. Nature 1998, 391:499-502.
    • (1998) Nature , vol.391 , pp. 499-502
    • Bitter, W.1    Gerrits, H.2    Kieft, R.3    Borst, P.4
  • 8
    • 0032514625 scopus 로고    scopus 로고
    • Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei
    • Chaves I., Zomerdijk J., Dirks M.A., Dirks R.W., Raap A.K., Borst P. Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:12328-12333.
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 12328-12333
    • Chaves, I.1    Zomerdijk, J.2    Dirks, M.A.3    Dirks, R.W.4    Raap, A.K.5    Borst, P.6
  • 9
    • 0033199568 scopus 로고    scopus 로고
    • Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei
    • Chaves I., Rudenko G., Dirks M.A., Cross M., Borst P. Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei. EMBO J. 1999, 18:4846-4855.
    • (1999) EMBO J. , vol.18 , pp. 4846-4855
    • Chaves, I.1    Rudenko, G.2    Dirks, M.A.3    Cross, M.4    Borst, P.5
  • 10
    • 84905324241 scopus 로고    scopus 로고
    • Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427
    • Cross G.A., Kim H.S., Wickstead B. Capturing the variant surface glycoprotein repertoire (the VSGnome) of Trypanosoma brucei Lister 427. Mol. Biochem. Parasitol. 2014, 195:59-73.
    • (2014) Mol. Biochem. Parasitol. , vol.195 , pp. 59-73
    • Cross, G.A.1    Kim, H.S.2    Wickstead, B.3
  • 11
    • 78649372822 scopus 로고    scopus 로고
    • The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei
    • Denninger V., Fullbrook A., Bessat M., Ersfeld K., Rudenko G. The FACT subunit TbSpt16 is involved in cell cycle specific control of VSG expression sites in Trypanosoma brucei. Mol. Microbiol. 2010, 78:459-474.
    • (2010) Mol. Microbiol. , vol.78 , pp. 459-474
    • Denninger, V.1    Fullbrook, A.2    Bessat, M.3    Ersfeld, K.4    Rudenko, G.5
  • 14
    • 79960031673 scopus 로고    scopus 로고
    • Nuclear architecture, genome and chromatin organisation in Trypanosoma brucei
    • Ersfeld K. Nuclear architecture, genome and chromatin organisation in Trypanosoma brucei. Res. Microbiol. 2011, 162:626-636.
    • (2011) Res. Microbiol. , vol.162 , pp. 626-636
    • Ersfeld, K.1
  • 16
    • 75649110809 scopus 로고    scopus 로고
    • Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes
    • Figueiredo L.M., Cross G.A. Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes. Eukaryot. Cell 2010, 9:148-154.
    • (2010) Eukaryot. Cell , vol.9 , pp. 148-154
    • Figueiredo, L.M.1    Cross, G.A.2
  • 17
    • 48349107004 scopus 로고    scopus 로고
    • A histone methyltransferase modulates antigenic variation in African trypanosomes
    • Figueiredo L.M., Janzen C.J., Cross G.A. A histone methyltransferase modulates antigenic variation in African trypanosomes. PLoS Biol. 2008, 6:e161.
    • (2008) PLoS Biol. , vol.6 , pp. e161
    • Figueiredo, L.M.1    Janzen, C.J.2    Cross, G.A.3
  • 18
    • 0037884882 scopus 로고    scopus 로고
    • Ex vivo and in vitro identification of a consensus promoter for VSG genes expressed by metacyclic-stage trypanosomes in the tsetse fly
    • Ginger M.L., Blundell P.A., Lewis A.M., Browitt A., Günzl A., Barry J.D. Ex vivo and in vitro identification of a consensus promoter for VSG genes expressed by metacyclic-stage trypanosomes in the tsetse fly. Eukaryot. Cell 2002, 1:1000-1009.
    • (2002) Eukaryot. Cell , vol.1 , pp. 1000-1009
    • Ginger, M.L.1    Blundell, P.A.2    Lewis, A.M.3    Browitt, A.4    Günzl, A.5    Barry, J.D.6
  • 19
    • 33646204183 scopus 로고    scopus 로고
    • Repression of polymerase I-mediated gene expression at Trypanosoma brucei telomeres
    • Glover L., Horn D. Repression of polymerase I-mediated gene expression at Trypanosoma brucei telomeres. EMBO Rep. 2006, 7:93-99.
    • (2006) EMBO Rep. , vol.7 , pp. 93-99
    • Glover, L.1    Horn, D.2
  • 20
    • 84887614639 scopus 로고    scopus 로고
    • Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control
    • Glover L., Hutchinson S., Alsford S., McCulloch R., Field M.C., Horn D. Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control. Cell. Microbiol. 2013, 15:1984-1993.
    • (2013) Cell. Microbiol. , vol.15 , pp. 1984-1993
    • Glover, L.1    Hutchinson, S.2    Alsford, S.3    McCulloch, R.4    Field, M.C.5    Horn, D.6
  • 21
    • 0022001302 scopus 로고
    • Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells
    • Grummt I., Skinner J.A. Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells. Proc. Natl. Acad. Sci. U. S. A. 1985, 82:722-726.
    • (1985) Proc. Natl. Acad. Sci. U. S. A. , vol.82 , pp. 722-726
    • Grummt, I.1    Skinner, J.A.2
  • 22
    • 84876342100 scopus 로고    scopus 로고
    • Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum
    • Guizetti J., Scherf A. Silence, activate, poise and switch! Mechanisms of antigenic variation in Plasmodium falciparum. Cell. Microbiol. 2013, 15:718-726.
    • (2013) Cell. Microbiol. , vol.15 , pp. 718-726
    • Guizetti, J.1    Scherf, A.2
  • 23
    • 77956841596 scopus 로고    scopus 로고
    • The pre-mRNA splicing machinery of trypanosomes: complex or simplified? Eukaryot
    • Günzl A. The pre-mRNA splicing machinery of trypanosomes: complex or simplified? Eukaryot. Cell 2010, 9:1159-1170.
    • (2010) Cell , vol.9 , pp. 1159-1170
    • Günzl, A.1
  • 24
    • 18844462890 scopus 로고    scopus 로고
    • RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei
    • Günzl A., Bruderer T., Laufer G., Schimanski B., Tu L.C., Chung H.M., Lee P.T., Lee M.G. RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei. Eukaryot. Cell 2003, 2:542-551.
    • (2003) Eukaryot. Cell , vol.2 , pp. 542-551
    • Günzl, A.1    Bruderer, T.2    Laufer, G.3    Schimanski, B.4    Tu, L.C.5    Chung, H.M.6    Lee, P.T.7    Lee, M.G.8
  • 25
    • 58149289691 scopus 로고    scopus 로고
    • Histone H1 and its isoforms: contribution to chromatin structure and function
    • Happel N., Doenecke D. Histone H1 and its isoforms: contribution to chromatin structure and function. Gene 2009, 431:1-12.
    • (2009) Gene , vol.431 , pp. 1-12
    • Happel, N.1    Doenecke, D.2
  • 27
    • 84906936962 scopus 로고    scopus 로고
    • Antigenic variation in African trypanosomes
    • Horn D. Antigenic variation in African trypanosomes. Mol. Biochem. Parasitol. 2014, 195:123-129.
    • (2014) Mol. Biochem. Parasitol. , vol.195 , pp. 123-129
    • Horn, D.1
  • 28
    • 0031464010 scopus 로고    scopus 로고
    • Position-dependent and promoter-specific regulation of gene expression in Trypanosoma brucei
    • Horn D., Cross G.A. Position-dependent and promoter-specific regulation of gene expression in Trypanosoma brucei. EMBO J. 1997, 16:7422-7431.
    • (1997) EMBO J. , vol.16 , pp. 7422-7431
    • Horn, D.1    Cross, G.A.2
  • 29
    • 78649657053 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the control of antigenic variation in African trypanosomes
    • Horn D., McCulloch R. Molecular mechanisms underlying the control of antigenic variation in African trypanosomes. Curr. Opin. Microbiol. 2010, 13:700-705.
    • (2010) Curr. Opin. Microbiol. , vol.13 , pp. 700-705
    • Horn, D.1    McCulloch, R.2
  • 31
    • 33747003677 scopus 로고    scopus 로고
    • Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei
    • Janzen C.J., Hake S.B., Lowell J.E., Cross G.A. Selective di- or trimethylation of histone H3 lysine 76 by two DOT1 homologs is important for cell cycle regulation in Trypanosoma brucei. Mol. Cell 2006, 23:497-507.
    • (2006) Mol. Cell , vol.23 , pp. 497-507
    • Janzen, C.J.1    Hake, S.B.2    Lowell, J.E.3    Cross, G.A.4
  • 32
    • 84902579069 scopus 로고    scopus 로고
    • Transcription is initiated on silent variant surface glycoprotein expression sites despite monoallelic expression in Trypanosoma brucei
    • Kassem A., Pays E., Vanhamme L. Transcription is initiated on silent variant surface glycoprotein expression sites despite monoallelic expression in Trypanosoma brucei. Proc. Natl. Acad. Sci. U. S. A. 2014, 111:8943-8948.
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 8943-8948
    • Kassem, A.1    Pays, E.2    Vanhamme, L.3
  • 33
    • 84874544393 scopus 로고    scopus 로고
    • MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei
    • Kim H.S., Park S.H., Günzl A., Cross G.A. MCM-BP is required for repression of life-cycle specific genes transcribed by RNA polymerase I in the mammalian infectious form of Trypanosoma brucei. PLoS One 2013, 8:e57001.
    • (2013) PLoS One , vol.8 , pp. e57001
    • Kim, H.S.1    Park, S.H.2    Günzl, A.3    Cross, G.A.4
  • 34
    • 84865277480 scopus 로고    scopus 로고
    • Antigenic variation and the generation of diversity in malaria parasites
    • Kirkman L.A., Deitsch K.W. Antigenic variation and the generation of diversity in malaria parasites. Curr. Opin. Microbiol. 2012, 15:456-462.
    • (2012) Curr. Opin. Microbiol. , vol.15 , pp. 456-462
    • Kirkman, L.A.1    Deitsch, K.W.2
  • 35
    • 84870680092 scopus 로고    scopus 로고
    • Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein
    • Kolev N.G., Ramey-Butler K., Cross G.A., Ullu E., Tschudi C. Developmental progression to infectivity in Trypanosoma brucei triggered by an RNA-binding protein. Science 2012, 338:1352-1353.
    • (2012) Science , vol.338 , pp. 1352-1353
    • Kolev, N.G.1    Ramey-Butler, K.2    Cross, G.A.3    Ullu, E.4    Tschudi, C.5
  • 36
    • 0021768580 scopus 로고
    • Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes
    • Kooter J.M., Borst P. Alpha-amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes. Nucleic Acids Res. 1984, 12:9457-9472.
    • (1984) Nucleic Acids Res. , vol.12 , pp. 9457-9472
    • Kooter, J.M.1    Borst, P.2
  • 37
    • 67749090919 scopus 로고    scopus 로고
    • Cohesin regulates VSG monoallelic expression in trypanosomes
    • Landeira D., Bart J.M., Van Tyne D., Navarro M. Cohesin regulates VSG monoallelic expression in trypanosomes. J. Cell Biol. 2009, 186:243-254.
    • (2009) J. Cell Biol. , vol.186 , pp. 243-254
    • Landeira, D.1    Bart, J.M.2    Van Tyne, D.3    Navarro, M.4
  • 38
    • 84882919875 scopus 로고    scopus 로고
    • Stochastic gene expression in mammals: lessons from olfaction
    • Magklara A., Lomvardas S. Stochastic gene expression in mammals: lessons from olfaction. Trends Cell Biol. 2013, 23:449-456.
    • (2013) Trends Cell Biol. , vol.23 , pp. 449-456
    • Magklara, A.1    Lomvardas, S.2
  • 40
    • 79955619183 scopus 로고    scopus 로고
    • Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome
    • Michaeli S. Trans-splicing in trypanosomes: machinery and its impact on the parasite transcriptome. Future Microbiol 2011, 6:459-474.
    • (2011) Future Microbiol , vol.6 , pp. 459-474
    • Michaeli, S.1
  • 41
    • 84876391617 scopus 로고    scopus 로고
    • TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes
    • Narayanan M.S., Rudenko G. TDP1 is an HMG chromatin protein facilitating RNA polymerase I transcription in African trypanosomes. Nucleic Acids Res. 2013, 41:2981-2992.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 2981-2992
    • Narayanan, M.S.1    Rudenko, G.2
  • 42
    • 79953693898 scopus 로고    scopus 로고
    • NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei
    • Narayanan M.S., Kushwaha M., Ersfeld K., Fullbrook A., Stanne T.M., Rudenko G. NLP is a novel transcription regulator involved in VSG expression site control in Trypanosoma brucei. Nucleic Acids Res. 2011, 39:2018-2031.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 2018-2031
    • Narayanan, M.S.1    Kushwaha, M.2    Ersfeld, K.3    Fullbrook, A.4    Stanne, T.M.5    Rudenko, G.6
  • 43
    • 0029951447 scopus 로고    scopus 로고
    • DNA rearrangements associated with multiple consecutive directed antigenic switches in Trypanosoma brucei
    • Navarro M., Cross G.A. DNA rearrangements associated with multiple consecutive directed antigenic switches in Trypanosoma brucei. Mol. Cell. Biol. 1996, 16:3615-3625.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 3615-3625
    • Navarro, M.1    Cross, G.A.2
  • 44
    • 0032128354 scopus 로고    scopus 로고
    • In situ analysis of a variant surface glycoprotein expression-site promoter region in Trypanosoma brucei
    • Navarro M., Cross G.A. In situ analysis of a variant surface glycoprotein expression-site promoter region in Trypanosoma brucei. Mol. Biochem. Parasitol. 1998, 94:53-66.
    • (1998) Mol. Biochem. Parasitol. , vol.94 , pp. 53-66
    • Navarro, M.1    Cross, G.A.2
  • 45
    • 0035856691 scopus 로고    scopus 로고
    • A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei
    • Navarro M., Gull K. A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei. Nature 2001, 414:759-763.
    • (2001) Nature , vol.414 , pp. 759-763
    • Navarro, M.1    Gull, K.2
  • 46
    • 84870431580 scopus 로고    scopus 로고
    • Characterization of a novel class I transcription factor A (CITFA) subunit that is indispensable for transcription by the multifunctional RNA polymerase I of Trypanosoma brucei
    • Nguyen T.N., Nguyen B.N., Lee J.H., Panigrahi A.K., Günzl A. Characterization of a novel class I transcription factor A (CITFA) subunit that is indispensable for transcription by the multifunctional RNA polymerase I of Trypanosoma brucei. Eukaryot. Cell 2012, 11:1573-1581.
    • (2012) Eukaryot. Cell , vol.11 , pp. 1573-1581
    • Nguyen, T.N.1    Nguyen, B.N.2    Lee, J.H.3    Panigrahi, A.K.4    Günzl, A.5
  • 47
    • 84898942049 scopus 로고    scopus 로고
    • Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei
    • Nguyen T.N., Müller L.S., Park S.H., Siegel T.N., Günzl A. Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei. Nucleic Acids Res. 2014, 42:3164-3176.
    • (2014) Nucleic Acids Res. , vol.42 , pp. 3164-3176
    • Nguyen, T.N.1    Müller, L.S.2    Park, S.H.3    Siegel, T.N.4    Günzl, A.5
  • 48
    • 84901456604 scopus 로고    scopus 로고
    • A new strategy of RNA interference that targets heterologous sequences reveals CITFA1 as an essential component of class I transcription factor A in Trypanosoma brucei
    • Park S.H., Nguyen B.N., Kirkham J.K., Nguyen T.N., Günzl A. A new strategy of RNA interference that targets heterologous sequences reveals CITFA1 as an essential component of class I transcription factor A in Trypanosoma brucei. Eukaryot. Cell 2014, 13:785-795.
    • (2014) Eukaryot. Cell , vol.13 , pp. 785-795
    • Park, S.H.1    Nguyen, B.N.2    Kirkham, J.K.3    Nguyen, T.N.4    Günzl, A.5
  • 49
    • 37349051368 scopus 로고    scopus 로고
    • Genomic rearrangements and transcriptional analysis of the spliced leader-associated retrotransposon in RNA interference-deficient Trypanosoma brucei
    • Patrick K.L., Luz P.M., Ruan J.P., Shi H., Ullu E., Tschudi C. Genomic rearrangements and transcriptional analysis of the spliced leader-associated retrotransposon in RNA interference-deficient Trypanosoma brucei. Mol. Microbiol. 2008, 67:435-447.
    • (2008) Mol. Microbiol. , vol.67 , pp. 435-447
    • Patrick, K.L.1    Luz, P.M.2    Ruan, J.P.3    Shi, H.4    Ullu, E.5    Tschudi, C.6
  • 51
    • 0029960292 scopus 로고    scopus 로고
    • A detailed mutational analysis of the VSG gene expression site promoter
    • Pham V.P., Qi C.C., Gottesdiener K.M. A detailed mutational analysis of the VSG gene expression site promoter. Mol. Biochem. Parasitol. 1996, 75:241-254.
    • (1996) Mol. Biochem. Parasitol. , vol.75 , pp. 241-254
    • Pham, V.P.1    Qi, C.C.2    Gottesdiener, K.M.3
  • 52
    • 84870793679 scopus 로고    scopus 로고
    • Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei
    • Povelones M.L., Gluenz E., Dembek M., Gull K., Rudenko G. Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei. PLoS Pathog. 2012, 8:e1003010.
    • (2012) PLoS Pathog. , vol.8 , pp. e1003010
    • Povelones, M.L.1    Gluenz, E.2    Dembek, M.3    Gull, K.4    Rudenko, G.5
  • 53
    • 84903199026 scopus 로고    scopus 로고
    • Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and Regulation
    • Springer Press, A. Bindereif (Ed.)
    • Preußer C., Jae N., Günzl A., Bindereif A. Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and Regulation. RNA Metabolism in Trypanosomes 2012, 49-76. Springer Press. A. Bindereif (Ed.).
    • (2012) RNA Metabolism in Trypanosomes , pp. 49-76
    • Preußer, C.1    Jae, N.2    Günzl, A.3    Bindereif, A.4
  • 54
    • 79952114536 scopus 로고    scopus 로고
    • Epigenetics and transcriptional control in African trypanosomes
    • Rudenko G. Epigenetics and transcriptional control in African trypanosomes. Essays Biochem. 2010, 48:201-219.
    • (2010) Essays Biochem. , vol.48 , pp. 201-219
    • Rudenko, G.1
  • 55
    • 0026000950 scopus 로고
    • RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei
    • Rudenko G., Chung H.M., Pham V.P., Van der Ploeg L.H. RNA polymerase I can mediate expression of CAT and neo protein-coding genes in Trypanosoma brucei. EMBO J. 1991, 10:3387-3397.
    • (1991) EMBO J. , vol.10 , pp. 3387-3397
    • Rudenko, G.1    Chung, H.M.2    Pham, V.P.3    Van der Ploeg, L.H.4
  • 57
    • 78650307411 scopus 로고    scopus 로고
    • The VSG C-terminal domain is inaccessible to antibodies on live trypanosomes
    • Schwede A., Jones N., Engstler M., Carrington M. The VSG C-terminal domain is inaccessible to antibodies on live trypanosomes. Mol. Biochem. Parasitol. 2011, 175:201-204.
    • (2011) Mol. Biochem. Parasitol. , vol.175 , pp. 201-204
    • Schwede, A.1    Jones, N.2    Engstler, M.3    Carrington, M.4
  • 58
    • 75649140875 scopus 로고    scopus 로고
    • Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes
    • Stanne T.M., Rudenko G. Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes. Eukaryot. Cell 2010, 9:136-147.
    • (2010) Eukaryot. Cell , vol.9 , pp. 136-147
    • Stanne, T.M.1    Rudenko, G.2
  • 59
    • 79960149832 scopus 로고    scopus 로고
    • TbISWI regulates multiple polymerase I (Pol I)-transcribed loci and is present at Pol II transcription boundaries in Trypanosoma brucei
    • Stanne T.M., Kushwaha M., Wand M., Taylor J.E., Rudenko G. TbISWI regulates multiple polymerase I (Pol I)-transcribed loci and is present at Pol II transcription boundaries in Trypanosoma brucei. Eukaryot. Cell 2011, 10:964-976.
    • (2011) Eukaryot. Cell , vol.10 , pp. 964-976
    • Stanne, T.M.1    Kushwaha, M.2    Wand, M.3    Taylor, J.E.4    Rudenko, G.5
  • 60
    • 84864321476 scopus 로고    scopus 로고
    • Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei
    • Tiengwe C., Marcello L., Farr H., Dickens N., Kelly S., Swiderski M., Vaughan D., Gull K., Barry J.D., Bell S.D., McCulloch R. Genome-wide analysis reveals extensive functional interaction between DNA replication initiation and transcription in the genome of Trypanosoma brucei. Cell Rep. 2012, 2:185-197.
    • (2012) Cell Rep. , vol.2 , pp. 185-197
    • Tiengwe, C.1    Marcello, L.2    Farr, H.3    Dickens, N.4    Kelly, S.5    Swiderski, M.6    Vaughan, D.7    Gull, K.8    Barry, J.D.9    Bell, S.D.10    McCulloch, R.11
  • 61
    • 0029117145 scopus 로고
    • Specific binding of proteins to the noncoding strand of a crucial element of the variant surface glycoprotein, procyclin, and ribosomal promoters of Trypanosoma brucei
    • Vanhamme L., Pays A., Tebabi P., Alexandre S., Pays E. Specific binding of proteins to the noncoding strand of a crucial element of the variant surface glycoprotein, procyclin, and ribosomal promoters of Trypanosoma brucei. Mol. Cell. Biol. 1995, 15:5598-5606.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5598-5606
    • Vanhamme, L.1    Pays, A.2    Tebabi, P.3    Alexandre, S.4    Pays, E.5
  • 62
    • 0034106940 scopus 로고    scopus 로고
    • Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei
    • Vanhamme L., Poelvoorde P., Pays A., Tebabi P., Xong H.V., Pays E. Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei. Mol. Microbiol. 2000, 36:328-340.
    • (2000) Mol. Microbiol. , vol.36 , pp. 328-340
    • Vanhamme, L.1    Poelvoorde, P.2    Pays, A.3    Tebabi, P.4    Xong, H.V.5    Pays, E.6
  • 63
    • 77956133527 scopus 로고    scopus 로고
    • Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes
    • Wang Q.P., Kawahara T., Horn D. Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes. Mol. Microbiol. 2010, 77:1237-1245.
    • (2010) Mol. Microbiol. , vol.77 , pp. 1237-1245
    • Wang, Q.P.1    Kawahara, T.2    Horn, D.3
  • 64
    • 63049115947 scopus 로고    scopus 로고
    • RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei
    • Yang X., Figueiredo L.M., Espinal A., Okubo E., Li B. RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei. Cell 2009, 137:99-109.
    • (2009) Cell , vol.137 , pp. 99-109
    • Yang, X.1    Figueiredo, L.M.2    Espinal, A.3    Okubo, E.4    Li, B.5
  • 66
    • 0025951442 scopus 로고
    • Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei
    • Zomerdijk J.C., Kieft R., Borst P. Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei. Nature 1991, 353:772-775.
    • (1991) Nature , vol.353 , pp. 772-775
    • Zomerdijk, J.C.1    Kieft, R.2    Borst, P.3
  • 67
    • 0025801525 scopus 로고
    • Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features
    • Zomerdijk J.C., Kieft R., Duyndam M., Shiels P.G., Borst P. Antigenic variation in Trypanosoma brucei: a telomeric expression site for variant-specific surface glycoprotein genes with novel features. Nucleic Acids Res. 1991, 19:1359-1368.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 1359-1368
    • Zomerdijk, J.C.1    Kieft, R.2    Duyndam, M.3    Shiels, P.G.4    Borst, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.