-
1
-
-
46749142123
-
Molecular pathogenesis of pulmonary arterial hypertension
-
Rabinovitch M. Molecular pathogenesis of pulmonary arterial hypertension. J Clin Invest 2008;118:2372-9.
-
(2008)
J Clin Invest
, vol.118
, pp. 2372-2379
-
-
Rabinovitch, M.1
-
2
-
-
54049138069
-
Emerging concepts and translational priorities in pulmonary arterial hypertension
-
Michelakis ED, Wilkins MR, Rabinovitch M. Emerging concepts and translational priorities in pulmonary arterial hypertension. Circulation 2008;118:1486-95.
-
(2008)
Circulation
, vol.118
, pp. 1486-1495
-
-
Michelakis, E.D.1
Wilkins, M.R.2
Rabinovitch, M.3
-
3
-
-
67649844313
-
Inflammation, growth factors, and pulmonary vascular remodeling
-
Hassoun PM, Mouthon L, Barberà JA, Eddahibi S, Flores SC, Grimminger F, et al. Inflammation, growth factors, and pulmonary vascular remodeling. J Am Coll Cardiol 2009;54 (1 Suppl):S10-S19.
-
(2009)
J am Coll Cardiol
, vol.54
, Issue.1
-
-
Hassoun, P.M.1
Mouthon, L.2
Barberà, J.A.3
Eddahibi, S.4
Flores, S.C.5
Grimminger, F.6
-
4
-
-
79960023557
-
Cell-based therapies in pulmonary hypertension: Who, what, and when?
-
Majka S, Burnham E, Stenmark KR. Cell-based therapies in pulmonary hypertension: Who, what, and when? Am J Physiol Lung Cell Mol Physiol 2011;301:L9-L11.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.301
, pp. LL9-L11
-
-
Majka, S.1
Burnham, E.2
Stenmark, K.R.3
-
5
-
-
76149089231
-
Endothelial progenitors in pulmonary hypertension: New pathophysiology and therapeutic implications
-
Fadini GP, Avogaro A, Ferraccioli G, Agostini C. Endothelial progenitors in pulmonary hypertension: New pathophysiology and therapeutic implications. Eur Respir J 2010;35:418-25.
-
(2010)
Eur Respir J
, vol.35
, pp. 418-425
-
-
Fadini, G.P.1
Avogaro, A.2
Ferraccioli, G.3
Agostini, C.4
-
6
-
-
34249302372
-
A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology
-
Macchia A, Marchioli R, Marfisi R, Scarano M, Levantesi G, Tavazzi L, et al. A meta-analysis of trials of pulmonary hypertension: A clinical condition looking for drugs and research methodology. Am Heart J 2007;153:1037-47.
-
(2007)
Am Heart J
, vol.153
, pp. 1037-1047
-
-
Macchia, A.1
Marchioli, R.2
Marfisi, R.3
Scarano, M.4
Levantesi, G.5
Tavazzi, L.6
-
7
-
-
80051729086
-
Clinical Trials Using Vasodilators in Pulmonary Arterial Hypertension: Where Do We Go from Here?
-
Macchia A, Mariani J, Comignani PD, Tognoni G. Clinical Trials Using Vasodilators in Pulmonary Arterial Hypertension: Where Do We Go from Here? Rev Recent Clin Trials, 2011;6:228-34.
-
(2011)
Rev Recent Clin Trials
, vol.6
, pp. 228-234
-
-
Macchia, A.1
Mariani, J.2
Comignani, P.D.3
Tognoni, G.4
-
8
-
-
71949129187
-
Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure
-
Stenmark KR, Meyrick B, Galie N, Mooi WJ, McMurtry IF. Animal models of pulmonary arterial hypertension: The hope for etiological discovery and pharmacological cure. Am J Physiol Lung Cell Mol Physiol 2009;297:L1013-L1032.
-
(2009)
Am J Physiol Lung Cell Mol Physiol
, vol.297
, pp. L1013-L1032
-
-
Stenmark, K.R.1
Meyrick, B.2
Galie, N.3
Mooi, W.J.4
McMurtry, I.F.5
-
9
-
-
84857027921
-
The Monocrotaline Model of Pulmonary Hypertension In Perspective
-
Gomez-Arroyo JG, Farkas L, Alhussaini AA, Farkas D, Kraskauskas D, Voelkel NF, et al. The Monocrotaline Model of Pulmonary Hypertension In Perspective. Am J Physiol Lung Cell Mol Physiol 2012;302:L363-L369.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L363-L369
-
-
Gomez-Arroyo, J.G.1
Farkas, L.2
Alhussaini, A.A.3
Farkas, D.4
Kraskauskas, D.5
Voelkel, N.F.6
-
10
-
-
78650186826
-
Strategic Plan for Lung Vascular Research: An NHLBI-ORDR Workshop Report
-
Erzurum S, Rounds SI, Stevens T, Aldred M, Aliotta J, Archer SL, et al. Strategic Plan for Lung Vascular Research: An NHLBI-ORDR Workshop Report. Am J Respir Crit Care Med 2010;182:1554-62.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1554-1562
-
-
Erzurum, S.1
Rounds, S.I.2
Stevens, T.3
Aldred, M.4
Aliotta, J.5
Archer, S.L.6
-
11
-
-
0035130107
-
Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension
-
Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, et al. Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension. Faseb J 2001;15:427-38.
-
(2001)
Faseb J
, vol.15
, pp. 427-438
-
-
Taraseviciene-Stewart, L.1
Kasahara, Y.2
Alger, L.3
Hirth, P.4
Mc Mahon, G.5
Waltenberger, J.6
-
12
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
Fong TA, Shawver LK, Sun L, Tang C, App H, Powell TJ, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res 1999;59:99-106.
-
(1999)
Cancer Res
, vol.59
, pp. 99-106
-
-
Fong, T.A.1
Shawver, L.K.2
Sun, L.3
Tang, C.4
App, H.5
Powell, T.J.6
-
13
-
-
84861165497
-
A Brief Overview of Mouse Models of Pulmonary Arterial Hypertension: Problems and Prospects
-
Gomez-Arroyo J, Saleem SJ, Mizuno S, Syed AA, Bogaard HJ, Abbate A, et al. A Brief Overview of Mouse Models of Pulmonary Arterial Hypertension: Problems and Prospects. Am J Physiol Lung Cell Mol Physiol 2012;302:L977-91.
-
(2012)
Am J Physiol Lung Cell Mol Physiol
, vol.302
, pp. L977-L991
-
-
Gomez-Arroyo, J.1
Saleem, S.J.2
Mizuno, S.3
Syed, A.A.4
Bogaard, H.J.5
Abbate, A.6
-
14
-
-
79952281574
-
The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension
-
Sakao S, Tatsumi K. The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension. Respiration 2011;81:253-61.
-
(2011)
Respiration
, vol.81
, pp. 253-261
-
-
Sakao, S.1
Tatsumi, K.2
-
15
-
-
0038389113
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth
-
Ameshima S, Golpon H, Cool CD, Chan D, Vandivier RW, Gardai SJ, et al. Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth. Circ Res 2003;92:1162-9.
-
(2003)
Circ Res
, vol.92
, pp. 1162-1169
-
-
Ameshima, S.1
Golpon, H.2
Cool, C.D.3
Chan, D.4
Vandivier, R.W.5
Gardai, S.J.6
-
16
-
-
80755128430
-
Design and validation of an endothelial progenitor cell capture chip and its application in patients with pulmonary arterial hypertension
-
Hansmann G, Plouffe BD, Hatch A, von Gise A, Sallmon H, Zamanian RT, et al. Design and validation of an endothelial progenitor cell capture chip and its application in patients with pulmonary arterial hypertension. J Mol Med (Berl) 2011;89:971-83.
-
(2011)
J Mol Med (Berl)
, vol.89
, pp. 971-983
-
-
Hansmann, G.1
Plouffe, B.D.2
Hatch, A.3
Von Gise, A.4
Sallmon, H.5
Zamanian, R.T.6
-
17
-
-
80053571093
-
Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension
-
Tamosiuniene R, Tian W, Dhillon G, Wang L, Sung YK, Gera L, et al. Regulatory T Cells Limit Vascular Endothelial Injury and Prevent Pulmonary Hypertension. Circ Res 2011;109:867-79.
-
(2011)
Circ Res
, vol.109
, pp. 867-879
-
-
Tamosiuniene, R.1
Tian, W.2
Dhillon, G.3
Wang, L.4
Sung, Y.K.5
Gera, L.6
-
18
-
-
84455168708
-
Altered microRNA Processing in Heritable Pulmonary Arterial Hypertension: An Important Role for Smad-8
-
Drake KM, Zygmunt D, Mavrakis L, Harbor P, Wang L, Comhair SA, et al. Altered microRNA Processing in Heritable Pulmonary Arterial Hypertension: An Important Role for Smad-8. Am J Respir Crit Care Med 2011;184:1400-8.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 1400-1408
-
-
Drake, K.M.1
Zygmunt, D.2
Mavrakis, L.3
Harbor, P.4
Wang, L.5
Comhair, S.A.6
-
19
-
-
51849167730
-
The cancer paradigm of severe pulmonary arterial hypertension
-
Rai PR, Cool CD, King JA, Stevens T, Burns N, Winn RA, et al. The cancer paradigm of severe pulmonary arterial hypertension. Am J Respir Crit Care Med 2008;178:558-64.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 558-564
-
-
Rai, P.R.1
Cool, C.D.2
King, J.A.3
Stevens, T.4
Burns, N.5
Winn, R.A.6
-
20
-
-
0033660171
-
Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
-
Kasahara Y, Tuder RM, Taraseviciene-Stewart L, Le Cras TD, Abman S, Hirth PK, et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 2000;106:1311-9.
-
(2000)
J Clin Invest
, vol.106
, pp. 1311-1319
-
-
Kasahara, Y.1
Tuder, R.M.2
Taraseviciene-Stewart, L.3
Le Cras, T.D.4
Abman, S.5
Hirth, P.K.6
-
21
-
-
79959229034
-
Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, on Experimental Corneal Neovascularization
-
Keskin U, Totan Y, Karadağ R, Erdurmuş M, Aydın B. Inhibitory Effects of SU5416, a Selective Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, on Experimental Corneal Neovascularization. Ophthalmic Res 2011;47:13-8.
-
(2011)
Ophthalmic Res
, vol.47
, pp. 13-18
-
-
Keskin, U.1
Totan, Y.2
Karadağ, R.3
Erdurmuş, M.4
Aydın, B.5
-
22
-
-
79951690500
-
Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells
-
Rasmussen JG, Frøbert O, Pilgaard L, Kastrup J, Simonsen U, Zachar V, et al. Prolonged hypoxic culture and trypsinization increase the pro-angiogenic potential of human adipose tissue-derived stem cells. Cytotherapy 2011;13:318-28.
-
(2011)
Cytotherapy
, vol.13
, pp. 318-328
-
-
Rasmussen, J.G.1
Frøbert, O.2
Pilgaard, L.3
Kastrup, J.4
Simonsen, U.5
Zachar, V.6
-
23
-
-
77956265222
-
Anti-vascular endothelial growth factor treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopoietic progenitor cells
-
Novitskiy SV, Csiki I, Huang Y, Johnson DH, Harth EM, Carbone DP, et al. Anti-vascular endothelial growth factor treatment in combination with chemotherapy delays hematopoietic recovery due to decreased proliferation of bone marrow hematopoietic progenitor cells. J Thorac Oncol 2010;5:1410-5.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1410-1415
-
-
Novitskiy, S.V.1
Csiki, I.2
Huang, Y.3
Johnson, D.H.4
Harth, E.M.5
Carbone, D.P.6
-
24
-
-
34547100056
-
VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice
-
Amura CR, Brodsky KS, Groff R, Gattone VH, Voelkel NF, Doctor RB. VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice. Am J Physiol Cell Physiol 2007;293:C419-C428.
-
(2007)
Am J Physiol Cell Physiol
, vol.293
, pp. C419-C428
-
-
Amura, C.R.1
Brodsky, K.S.2
Groff, R.3
Gattone, V.H.4
Voelkel, N.F.5
Doctor, R.B.6
-
25
-
-
77449131068
-
Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke
-
Shimotake J, Derugin N, Wendland M, Vexler ZS, Ferriero DM. Vascular endothelial growth factor receptor-2 inhibition promotes cell death and limits endothelial cell proliferation in a neonatal rodent model of stroke. Stroke 2010;41:343-9.
-
(2010)
Stroke
, vol.41
, pp. 343-349
-
-
Shimotake, J.1
Derugin, N.2
Wendland, M.3
Vexler, Z.S.4
Ferriero, D.M.5
-
26
-
-
0033826997
-
Inhibition of angiogenesis decreases alveolarization in the developing rat lung
-
Jakkula M, Le Cras TD, Gebb S, Hirth KP, Tuder RM, Voelkel NF, et al. Inhibition of angiogenesis decreases alveolarization in the developing rat lung. Am J Physiol Lung Cell Mol Physiol 2000;279:L600-L607.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
, pp. L600-L607
-
-
Jakkula, M.1
Le Cras, T.D.2
Gebb, S.3
Hirth, K.P.4
Tuder, R.M.5
Voelkel, N.F.6
-
27
-
-
77954243018
-
Formation of plexiform lesions in experimental severe pulmonary arterial hypertension
-
Abe K, Toba M, Alzoubi A, Ito M, Fagan KA, Cool CD, et al. Formation of plexiform lesions in experimental severe pulmonary arterial hypertension. Circulation 2010;121:2747-54.
-
(2010)
Circulation
, vol.121
, pp. 2747-2754
-
-
Abe, K.1
Toba, M.2
Alzoubi, A.3
Ito, M.4
Fagan, K.A.5
Cool, C.D.6
-
28
-
-
34147189502
-
Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, et al. Rho Kinase-Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats. Circ Res 2007;100:923-9.
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
-
29
-
-
33749362588
-
Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension
-
Taraseviciene-Stewart L, Scerbavicius R, Choe KH, Cool C, Wood K, Tuder RM, et al. Simvastatin causes endothelial cell apoptosis and attenuates severe pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2006;291:L668-L676.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.291
, pp. L668-L676
-
-
Taraseviciene-Stewart, L.1
Scerbavicius, R.2
Choe, K.H.3
Cool, C.4
Wood, K.5
Tuder, R.M.6
-
30
-
-
72449124776
-
Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure
-
Bogaard HJ, Natarajan R, Henderson SC, Long CS, Kraskauskas D, Smithson L, et al. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation 2009;120:1951-60.
-
(2009)
Circulation
, vol.120
, pp. 1951-1960
-
-
Bogaard, H.J.1
Natarajan, R.2
Henderson, S.C.3
Long, C.S.4
Kraskauskas, D.5
Smithson, L.6
-
31
-
-
29244486514
-
Autoimmunity and pulmonary hypertension: A perspective
-
Nicolls MR, Taraseviciene-Stewart L, Rai PR, Badesch DB, Voelkel NF. Autoimmunity and pulmonary hypertension: A perspective. Eur Respir J 2005;26:1110-8.
-
(2005)
Eur Respir J
, vol.26
, pp. 1110
-
-
Nicolls, M.R.1
Taraseviciene-Stewart, L.2
Rai, P.R.3
Badesch, D.B.4
Voelkel, N.F.5
-
32
-
-
34250205557
-
Absence of T Cells Confers Increased Pulmonary Arterial Hypertension and Vascular Remodeling
-
Taraseviciene-Stewart L, Nicolls MR, Kraskauskas D, Scerbavicius R, Burns N, Cool C, et al. Absence of T Cells Confers Increased Pulmonary Arterial Hypertension and Vascular Remodeling. Am J Respir Crit Care Med 2007;175:1280-9.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1280-1289
-
-
Taraseviciene-Stewart, L.1
Nicolls, M.R.2
Kraskauskas, D.3
Scerbavicius, R.4
Burns, N.5
Cool, C.6
-
33
-
-
0034018782
-
Athymic nude rats develop severe pulmonary hypertension following monocrotaline administration
-
Miyata M, Sakuma F, Ito M, Ohira H, Sato Y, Kasukawa R. Athymic nude rats develop severe pulmonary hypertension following monocrotaline administration. Int Arch Allergy Immunol 2000;121:246-52.
-
(2000)
Int Arch Allergy Immunol
, vol.121
, pp. 246-252
-
-
Miyata, M.1
Sakuma, F.2
Ito, M.3
Ohira, H.4
Sato, Y.5
Kasukawa, R.6
-
36
-
-
39549087002
-
Pulmonary arterial remodeling induced by a Th2 immune response
-
Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, et al. Pulmonary arterial remodeling induced by a Th2 immune response. J Exp Med 2008;205:361-72.
-
(2008)
J Exp Med
, vol.205
, pp. 361-372
-
-
Daley, E.1
Emson, C.2
Guignabert, C.3
De Waal Malefyt, R.4
Louten, J.5
Kurup, V.P.6
-
37
-
-
38049153144
-
A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kappaB and hypoxia-inducible factor-1alpha
-
Lee KS, Kim SR, Park HS, Park SJ, Min KH, Lee KY, et al. A novel thiol compound, N-acetylcysteine amide, attenuates allergic airway disease by regulating activation of NF-kappaB and hypoxia-inducible factor-1alpha. Exp Mol Med 2007;39:756-68.
-
(2007)
Exp Mol Med
, vol.39
, pp. 756-768
-
-
Lee, K.S.1
Kim, S.R.2
Park, H.S.3
Park, S.J.4
Min, K.H.5
Lee, K.Y.6
-
38
-
-
84868309560
-
Severe Pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization
-
[In Press]
-
Mizuno S, Farkas L, Alhussaini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, et al. Severe Pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. Am J Respir Cell Mol Biol 2012 [In Press].
-
(2012)
Am J Respir Cell Mol Biol
-
-
Mizuno, S.1
Farkas, L.2
Alhussaini, A.3
Farkas, D.4
Gomez-Arroyo, J.5
Kraskauskas, D.6
-
39
-
-
85026314053
-
Vegf receptor inhibition in experimental lung fibrosis results in severe angioproliferative pulmonary hypertension and increased fibrogenic activity
-
Farkas L, et al. Vegf receptor inhibition in experimental lung fibrosis results in severe angioproliferative pulmonary hypertension and increased fibrogenic activity Am J Respir Crit Care Med 2010;181:A6315.
-
(2010)
Am J Respir Crit Care Med
, vol.181
-
-
Farkas, L.1
-
40
-
-
66449098872
-
VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats
-
Farkas L, Farkas D, Ask K, Möller A, Gauldie J, Margetts P, et al. VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. J Clin Invest 2009;119:1298-311.
-
(2009)
J Clin Invest
, vol.119
, pp. 1298-1311
-
-
Farkas, L.1
Farkas, D.2
Ask, K.3
Möller, A.4
Gauldie, J.5
Margetts, P.6
-
41
-
-
85026305171
-
Caspase inhibition reduces severe pulmonary hypertension in the AdTGF-1β/SU5416 model of angioproliferative pulmonary hypertension and lung fibrosis
-
Farkas L, Farkas D, Kraskauskas D, Gauldie J, Kolb M, Voelkel N. Caspase inhibition reduces severe pulmonary hypertension in the AdTGF-1β/SU5416 model of angioproliferative pulmonary hypertension and lung fibrosis. Eur Respir J 2011;38:594s.
-
(2011)
Eur Respir J
, vol.38
-
-
Farkas, L.1
Farkas, D.2
Kraskauskas, D.3
Gauldie, J.4
Kolb, M.5
Voelkel, N.6
-
42
-
-
84878644800
-
The Pathobiology of the Complex Vascular Lesions in Severe Pulmonary Hypertension-Angiogenesis and Cancer
-
N.V. Ed, Editor. Connecticut: People’s Medical Publishing House Shelton
-
Voelkel NF, Cool CD. The Pathobiology of the Complex Vascular Lesions in Severe Pulmonary Hypertension-Angiogenesis and Cancer, in Pulmonary Hypertension: The Present and Future. N.V. Ed, Editor. Connecticut: People’s Medical Publishing House Shelton; 2011. p. 87-103.
-
(2011)
Pulmonary Hypertension: The Present and Future
, pp. 87
-
-
Voelkel, N.F.1
Cool, C.D.2
-
43
-
-
0036245561
-
Janus face of vascular endothelial growth factor: The obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension
-
Voelkel NF, Cool C, Taraceviene-Stewart L, Geraci MW, Yeager M, Bull T, et al. Janus face of vascular endothelial growth factor: The obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Crit Care Med 2002;30 (5 Suppl):S251-S256.
-
(2002)
Crit Care Med
, vol.30
, Issue.5
-
-
Voelkel, N.F.1
Cool, C.2
Taraceviene-Stewart, L.3
Geraci, M.W.4
Yeager, M.5
Bull, T.6
-
44
-
-
84861207235
-
Role of shear
-
dela Paz NG, Walshe TE, Leach LL, Saint-Geniez M, D’Amore PA. Role of shear-stress-induced VEGF expression in endothelial cell survival. J Cell Sci 2012;125:831-43.
-
(2012)
J Cell Sci
, vol.125
, pp. 831-843
-
-
Dela Paz, N.G.1
Walshe, T.E.2
Leach, L.L.3
Saint-Geniez, M.4
D’Amore, P.A.5
-
46
-
-
84860346274
-
Pulmonary arterial hypertension in patients treated by dasatinib
-
Montani D, Bergot E, Günther S, Savale L, Bergeron A, Bourdin A, et al. Pulmonary arterial hypertension in patients treated by dasatinib. Circulation 2012;125:2128-37.
-
(2012)
Circulation
, vol.125
, pp. 2128-2137
-
-
Montani, D.1
Bergot, E.2
Günther, S.3
Savale, L.4
Bergeron, A.5
Bourdin, A.6
-
47
-
-
21744460365
-
Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells
-
Sakao S, Taraseviciene-Stewart L, Lee JD, Wood K, Cool CD, Voelkel NF. Initial apoptosis is followed by increased proliferation of apoptosis-resistant endothelial cells. Faseb J 2005;19:1178-80.
-
(2005)
Faseb J
, vol.19
, pp. 1178-1180
-
-
Sakao, S.1
Taraseviciene-Stewart, L.2
Lee, J.D.3
Wood, K.4
Cool, C.D.5
Voelkel, N.F.6
-
48
-
-
33845343558
-
Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy
-
Li B, Lalani AS, Harding TC, Luan B, Koprivnikar K, Huan Tu G, Prell R, et al. Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. Clin Cancer Res 2006;12:6808-16.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6808-6816
-
-
Li, B.1
Lalani, A.S.2
Harding, T.C.3
Luan, B.4
Koprivnikar, K.5
Huan Tu, G.6
Prell, R.7
-
49
-
-
84860122847
-
Bevacizumab and breast cancer: What does the future hold?
-
Stevenson CE, Nagahashi M, Ramachandran S, Yamada A, Bear HD, Takabe K. Bevacizumab and breast cancer: What does the future hold? Future Oncol 2012;8:403-14.
-
(2012)
Future Oncol
, vol.8
, pp. 403-414
-
-
Stevenson, C.E.1
Nagahashi, M.2
Ramachandran, S.3
Yamada, A.4
Bear, H.D.5
Takabe, K.6
-
50
-
-
77953988924
-
Targeting the tumour vasculature: Insights from physiological angiogenesis
-
Chung AS, Lee J, Ferrara N. Targeting the tumour vasculature: Insights from physiological angiogenesis. Nat Rev Cancer 2010;10:505-14.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 505-514
-
-
Chung, A.S.1
Lee, J.2
Ferrara, N.3
-
51
-
-
79953244361
-
Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis
-
Ebos JM, Kerbel RS. Antiangiogenic therapy: Impact on invasion, disease progression, and metastasis. Nat Rev Clin Oncol 2011;8:210-21.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 210
-
-
Ebos, J.M.1
Kerbel, R.S.2
-
52
-
-
0033558087
-
Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2
-
Soldi R, Mitola S, Strasly M, Defilippi P, Tarone G, Bussolino F. Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2. EMBO J 1999;18:882-92.
-
(1999)
EMBO J
, vol.18
, pp. 882-892
-
-
Soldi, R.1
Mitola, S.2
Strasly, M.3
Defilippi, P.4
Tarone, G.5
Bussolino, F.6
-
53
-
-
14244262503
-
Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2
-
Hall H, Hubbell JA. Matrix-bound sixth Ig-like domain of cell adhesion molecule L1 acts as an angiogenic factor by ligating alphavbeta3-integrin and activating VEGF-R2. Microvasc Res 2004;68:169-78.
-
(2004)
Microvasc Res
, vol.68
, pp. 169-178
-
-
Hall, H.1
Hubbell, J.A.2
-
54
-
-
84872198058
-
Thyroid hormone is highly permissive in angioproliferative pulmonary arterial hypertension in rats
-
[In Press]
-
Al Husseini A, Bagnato G, Farkas L, Gomez-Arroyo J, Farkas D, Mizuno S, et al. Thyroid hormone is highly permissive in angioproliferative pulmonary arterial hypertension in rats. Eur Respir J 2012 [In Press].
-
(2012)
Eur Respir J
-
-
Al Husseini, A.1
Bagnato, G.2
Farkas, L.3
Gomez-Arroyo, J.4
Farkas, D.5
Mizuno, S.6
-
55
-
-
84860540044
-
Copper-dependence of angioproliferation in pulmonary arterial hypertension
-
Bogaard HJ, Mizuno S, Guignabert C, Al Hussaini AA, Farkas D, Ruiters G, et al. Copper-dependence of angioproliferation in pulmonary arterial hypertension. Am J Respir Cell Mol Biol 2012;46:582-91.
-
(2012)
Am J Respir Cell Mol Biol
, vol.46
, pp. 582-591
-
-
Bogaard, H.J.1
Mizuno, S.2
Guignabert, C.3
Al Hussaini, A.A.4
Farkas, D.5
Ruiters, G.6
-
56
-
-
85026308112
-
Endocrine aspects of pulmonary hypertension
-
Shelton, Connecticut: People’s Medical Publishing House
-
Sweeney L, Chhatwani L. Endocrine aspects of pulmonary hypertension, in Pulmonary hypertension: Present and future. Shelton, Connecticut: People’s Medical Publishing House; 2011. p. 239-49.
-
(2011)
Pulmonary Hypertension: Present and Future
, pp. 239
-
-
Sweeney, L.1
Chhatwani, L.2
-
57
-
-
77955056839
-
Cardiovascular involvement in patients with different causes of hyperthyroidism
-
Biondi B, Kahaly GJ. Cardiovascular involvement in patients with different causes of hyperthyroidism. Nat Rev Endocrinol 2010;6:431-43.
-
(2010)
Nat Rev Endocrinol
, vol.6
, pp. 431-443
-
-
Biondi, B.1
Kahaly, G.J.2
-
58
-
-
2942653137
-
Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface
-
Davis FB, Mousa SA, O’Connor L, Mohamed S, Lin HY, Cao HJ, et al. Proangiogenic action of thyroid hormone is fibroblast growth factor-dependent and is initiated at the cell surface. Circ Res 2004;94:1500-6.
-
(2004)
Circ Res
, vol.94
, pp. 1500-1506
-
-
Davis, F.B.1
Mousa, S.A.2
O’Connor, L.3
Mohamed, S.4
Lin, H.Y.5
Cao, H.J.6
-
59
-
-
0032498640
-
Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis
-
Eliceiri BP, Klemke R, Strömblad S, Cheresh DA. Integrin alphavbeta3 requirement for sustained mitogen-activated protein kinase activity during angiogenesis. J Cell Biol 1998;140:1255-63.
-
(1998)
J Cell Biol
, vol.140
, pp. 1255-1263
-
-
Eliceiri, B.P.1
Klemke, R.2
Strömblad, S.3
Cheresh, D.A.4
-
60
-
-
84862768329
-
Predicting the Effects of Anti-angiogenic Agents Targeting Specific VEGF Isoforms
-
Finley SD, Popel AS. Predicting the Effects of Anti-angiogenic Agents Targeting Specific VEGF Isoforms. AAPS J 2012;14:500-9.
-
(2012)
AAPS J
, vol.14
, pp. 500-509
-
-
Finley, S.D.1
Popel, A.S.2
-
61
-
-
84859453770
-
Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling
-
Benedito R, Rocha SF, Woeste M, Zamykal M, Radtke F, Casanovas O, et al. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling. Nature 2012;484:110-4.
-
(2012)
Nature
, vol.484
, pp. 110-114
-
-
Benedito, R.1
Rocha, S.F.2
Woeste, M.3
Zamykal, M.4
Radtke, F.5
Casanovas, O.6
-
62
-
-
2342486598
-
Internal and external autocrine VEGF/KDR loops regulate survival of subsets of acute leukemia through distinct signaling pathways
-
Santos SC, Dias S. Internal and external autocrine VEGF/KDR loops regulate survival of subsets of acute leukemia through distinct signaling pathways. Blood 2004;103:3883-9.
-
(2004)
Blood
, vol.103
, pp. 3883-3889
-
-
Santos, S.C.1
Dias, S.2
-
63
-
-
80053242320
-
VEGFR2 translocates to the nucleus to regulate its own transcription
-
Domingues I, Rino J, Demmers JA, de Lanerolle P, Santos SC. VEGFR2 translocates to the nucleus to regulate its own transcription. PLoS One 2011;6:e25668.
-
(2011)
Plos One
, vol.6
-
-
Domingues, I.1
Rino, J.2
Demmers, J.A.3
De Lanerolle, P.4
Santos, S.C.5
-
64
-
-
84861116064
-
VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics
-
Lund AW, Duraes FV, Hirosue S, Raghavan VR, Nembrini C, Thomas SN, et al. VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics. Cell Reports 2012;1:191-9.
-
(2012)
Cell Reports
, vol.1
, pp. 191-199
-
-
Lund, A.W.1
Duraes, F.V.2
Hirosue, S.3
Raghavan, V.R.4
Nembrini, C.5
Thomas, S.N.6
-
65
-
-
84857407549
-
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
-
Conley SJ, Gheordunescu E, Kakarala P, Newman B, Korkaya H, Heath AN, et al. Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia. Proc Natl Acad Sci U S A 2012; 109:2784-9.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 2784-2789
-
-
Conley, S.J.1
Gheordunescu, E.2
Kakarala, P.3
Newman, B.4
Korkaya, H.5
Heath, A.N.6
-
66
-
-
0030828893
-
Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension
-
Okada K, Tanaka Y, Bernstein M, Zhang W, Patterson GA, Botney MD. Pulmonary hemodynamics modify the rat pulmonary artery response to injury. A neointimal model of pulmonary hypertension. Am J Pathol 1997;151:1019-25.
-
(1997)
Am J Pathol
, vol.151
, pp. 1019-1025
-
-
Okada, K.1
Tanaka, Y.2
Bernstein, M.3
Zhang, W.4
Patterson, G.A.5
Botney, M.D.6
-
67
-
-
82755165210
-
Molecular signature of a right heart failure program in chronic severe pulmonary hypertension
-
Drake JI, Bogaard HJ, Mizuno S, Clifton B, Xie B, Gao Y, et al. Molecular signature of a right heart failure program in chronic severe pulmonary hypertension. Am J Respir Cell Mol Biol 2011;45:1239-47.
-
(2011)
Am J Respir Cell Mol Biol
, vol.45
, pp. 1239-1247
-
-
Drake, J.I.1
Bogaard, H.J.2
Mizuno, S.3
Clifton, B.4
Xie, B.5
Gao, Y.6
-
68
-
-
34547106845
-
Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF
-
Huang Y, Chen X, Dikov MM, Novitskiy SV, Mosse CA, Yang L, et al. Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF. Blood 2007;110:624-31.
-
(2007)
Blood
, vol.110
, pp. 624-631
-
-
Huang, Y.1
Chen, X.2
Dikov, M.M.3
Novitskiy, S.V.4
Mosse, C.A.5
Yang, L.6
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