Ceramide synthase 5 is essential to maintain C16:0-Ceramide pools and contributes to the development of diet-induced obesity

Journal of Biological Chemistry

Volumn 291, Issue 13, 2016, Pages 6989-7003

  Gosejacob, Dominic ^a   Jäger, Philipp S ^a   Dorp, Katharina Vom ^a   Frejno, Martin ^a   Carstensen, Anne C ^a   Köhnke, Monika ^a   Degen, Joachim ^a   Dörmann, Peter ^a   Hoch, Michael ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHAINS; MAMMALS; MUSCLE; NUTRITION; PHYSIOLOGY; TISSUE; TISSUE HOMEOSTASIS;

DIET-INDUCED OBESITY; ENERGY HOMEOSTASIS; FEEDING CONDITIONS; GENETIC INHIBITION; GLUCOSE HOMEOSTASIS; GLYCEROPHOSPHOLIPIDS; INSULIN RESISTANCE; WHITE ADIPOSE TISSUES;

CERAMIDES;

CERAMIDE SYNTHASE 5; GLYCEROPHOSPHOLIPID; SYNTHETASE; UNCLASSIFIED DRUG; CERAMIDE; FAT INTAKE; GLUCOSE BLOOD LEVEL; ISOENZYME; SPHINGOSINE ACYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CERS5 GENE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENE FUNCTION; GENE LOSS; GENE SEQUENCE; GLUCOSE HOMEOSTASIS; HOMOLOGOUS RECOMBINATION; LIPID COMPOSITION; MALE; MOUSE; NONHUMAN; OBESITY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE LEVEL; WEIGHT GAIN; WHITE ADIPOSE TISSUE; ADVERSE EFFECTS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DEFICIENCY; ENZYMOLOGY; FAT INTAKE; GENETICS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID DIET; LIVER; LUNG; METABOLISM; PATHOLOGY; SKELETAL MUSCLE; SPLEEN;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD GLUCOSE; CERAMIDES; DIET, HIGH-FAT; DIETARY FATS; GENE EXPRESSION; GLUCOSE TOLERANCE TEST; INSULIN RESISTANCE; ISOENZYMES; LIVER; LUNG; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SKELETAL; OBESITY; SPHINGOSINE N-ACYLTRANSFERASE; SPLEEN;

EID: 84964857154     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.691212     Document Type: Article

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