Ablation of neuronal ceramide synthase 1 in mice decreases ganglioside levels and expression of myelin-associated glycoprotein in oligodendrocytes

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 41888-41902

  Ginkel, Christina ^a   Hartmann, Dieter ^a   Vom Dorp, Katharina ^a   Zlomuzica, Armin ^b   Farwanah, Hany ^a   Eckhardt, Matthias ^a   Sandhoff, Roger ^c   Degen, Joachim ^a   Rabionet, Mariona ^c   Dere, Ekrem ^d   Dörmann, Peter ^a   Sandhoff, Konrad ^a   Willecke, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

^b RUHR UNIVERSITY BOCHUM   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d SORBONNE UNIVERSITÉ   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BEHAVIORAL ANALYSIS; BIOLOGICAL FUNCTIONS; C-TERMINAL REGIONS; CELL TYPES; CERAMIDE SYNTHASE; CERAMIDES; CODING REGION; MASS SPECTROMETRIC ANALYSIS; MEMBRANE ANCHORS; MOTOR CO-ORDINATION; MOUSE BRAIN; NEURONAL APOPTOSIS; OLIGODENDROCYTES; SPHINGOLIPIDS; WILD TYPES;

AMIDES; BIOMECHANICS; BRAIN; CELL DEATH; GLYCOPROTEINS; NEURONS; PROTEINS;

MAMMALS;

CERAMIDE; CERAMIDE SYNTHASE 1; GANGLIOSIDE; MYELIN ASSOCIATED GLYCOPROTEIN; SPHINGOLIPID; SYNTHETASE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ATROPHY; BRAIN DEVELOPMENT; CEREBELLUM; CERS1 GENE; CONTROLLED STUDY; EMBRYO; EXPLORATORY BEHAVIOR; FOREBRAIN; GENE MUTATION; LOCOMOTION; MASS SPECTROMETRY; MOTOR COORDINATION; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STABILITY;

ANIMALS; APOPTOSIS; CELL LINE; CERAMIDES; CEREBELLUM; GANGLIOSIDES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MICE, MUTANT STRAINS; MYELIN-ASSOCIATED GLYCOPROTEIN; NEURONS; OLIGODENDROGLIA; OXIDOREDUCTASES; PROSENCEPHALON;

MUS;

EID: 84871317821     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.413500     Document Type: Article

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