Ceramide synthase-dependent ceramide generation and programmed cell death: Involvement of salvage pathway in regulating postmitochondrial events

Journal of Biological Chemistry

Volumn 286, Issue 18, 2011, Pages 15929-15942

  Mullen, Thomas D ^b   Jenkins, Russell W ^b   Clarke, Christopher J ^b   Bielawski, Jacek ^b   Hannun, Yusuf A ^b   Obeid, Lina M ^a,b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; CASPASES; CELLULAR STRESS; CERAMIDE SYNTHASE; CERAMIDES; DE NOVO SYNTHESIS; EXECUTION PHASE; EXPERIMENTAL MODELS; FUMONISIN B1; MEMBRANE PERMEABILITY; MITOCHONDRIAL PATHWAYS; MYRIOCIN; PLASMA MEMBRANES; PROGRAMMED CELL DEATHS; SALVAGE PATHWAY; SPHINGOLIPIDS; SPHINGOMYELIN; SPHINGOSINE; ULTRA-VIOLET LIGHT;

CELL DEATH; CELL MEMBRANES; LAKES; ULTRAVIOLET RADIATION;

AMIDES;

CASPASE; CASPASE 7; CERAMIDE; CERAMIDE HEXOSIDE; CERAMIDE SYNTHASE 5; CERAMIDE SYNTHASE 6; DIHYDROCERAMIDE; FUMONISIN B1; PROTEIN BAK; PROTEIN BCL XL; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOSINE ACYLTRANSFERASE; THERMOZYMOCIDIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL LEVEL; CELL MEMBRANE PERMEABILITY; CELL STRAIN MCF 7; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIPOGENESIS; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; RADIATION RESPONSE; SIGNAL TRANSDUCTION; ULTRAVIOLET C RADIATION;

APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-X PROTEIN; CASPASE 7; CELL LINE, TUMOR; CERAMIDES; ENZYME INHIBITORS; FUMONISINS; HUMANS; OXIDOREDUCTASES; SPHINGOSINE; ULTRAVIOLET RAYS;

EID: 79955533796     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.230870     Document Type: Article

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