The genetic variability of UCP4 affects the individual susceptibility to late-onset Alzheimer's disease and modifies the disease's risk in apoe- ϵ 4 carriers

Journal of Alzheimer's Disease

Volumn 51, Issue 4, 2016, Pages 1265-1274

  Montesanto, Alberto ^a   Crocco, Paolina ^a   Anfossi, Maria ^b   Smirne, Nicoletta ^b   Puccio, Gianfranco ^b   Colao, Rosanna ^b   Maletta, Raffaele ^b   Passarino, Giuseppe ^a   Bruni, Amalia C ^b   Rose, Giuseppina ^a  

^a UNIVERSITY OF CALABRIA   (Italy)

^b Regional Neurogenetic Centre   (Italy)

Author keywords

Alzheimer's disease; APOE; genetic risk; mitochondria; neurodegeneration; UCP4; uncoupling proteins

Indexed keywords

APOLIPOPROTEIN E4; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN; UNCOUPLING PROTEIN 2; UNCOUPLING PROTEIN 3; UNCOUPLING PROTEIN 4; UNCOUPLING PROTEIN 5; SLC25A27 PROTEIN, HUMAN;

AGED; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENE DOSAGE; GENE FREQUENCY; GENE INTERACTION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; DIAGNOSTIC IMAGING; GENETIC ASSOCIATION STUDY; GENETICS; MENTAL HEALTH; NEUROIMAGING; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; HUMANS; MALE; MENTAL STATUS SCHEDULE; MITOCHONDRIAL UNCOUPLING PROTEINS; NEUROIMAGING; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84964808854     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150993     Document Type: Article

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