Correlation of Organic Cation/Carnitine Transporter 1 and Multidrug Resistance-Associated Protein 1 Transport Activities with Protein Expression Levels in Primary Cultured Human Tracheal, Bronchial, and Alveolar Epithelial Cells

Journal of Pharmaceutical Sciences

Volumn 105, Issue 2, 2016, Pages 876-883

  Sakamoto, Atsushi ^a,b   Suzuki, Shinobu ^a   Matsumaru, Takehisa ^a   Yamamura, Norio ^a   Uchida, Yasuo ^b   Tachikawa, Masanori ^b   Terasaki, Tetsuya ^b  

^a NIPPON BOEHRINGER INGELHEIM CO LTD   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

Author keywords

ABC transporters; drug transport; individualized drug therapy; mass spectrometry; membrane transporter; multidrug resistance associated proteins; organic cation transporters (OCT); proteomics; pulmonary drug delivery; targeted drug delivery

Indexed keywords

4 [4 (DIMETHYLAMINO) STYRYL] N METHYLPYRIDINIUM IODIDE; CARBOXY DICHLOROFLUORESCEIN; CARNITINE TRANSPORTER 1; DICHLOROFLUORESCEIN; FLUORESCENT DYE; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; UNCLASSIFIED DRUG; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; ORGANIC CATION TRANSPORTER; SLC22A4 PROTEIN, HUMAN;

ARTICLE; BRONCHUS; CELL CULTURE; CELL MEMBRANE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG TRANSPORT; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM CELL; MASS SPECTROMETRY; MICHAELIS CONSTANT; NORMAL HUMAN; PROTEIN EXPRESSION; TRACHEA; BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION REGULATION; LUNG ALVEOLUS; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; RESPIRATORY MUCOSA;

BRONCHI; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGANIC CATION TRANSPORT PROTEINS; PROTEIN TRANSPORT; PULMONARY ALVEOLI; RESPIRATORY MUCOSA; TRACHEA;

EID: 84964452160     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.24661     Document Type: Article

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