메뉴 건너뛰기




Volumn 6, Issue 1, 2015, Pages

Expression of drug transporters in human kidney: Impact of sex, age, and ethnicity

Author keywords

Age; ATP binding cassettes (ABCs); Drug transporters; Ethnicity; Gene expression; Kidney; Sex difference; Solute carriers (SLCs)

Indexed keywords


EID: 84927765622     PISSN: None     EISSN: 20426410     Source Type: Journal    
DOI: 10.1186/s13293-015-0020-3     Document Type: Article
Times cited : (49)

References (50)
  • 4
    • 34547169521 scopus 로고    scopus 로고
    • Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
    • Hilgendorf C, Ahlin G, Seithel A, Artursson P, Ungell AL, Karlsson J. Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines. Drug Metab Dispos. 2007;35:1333-40.
    • (2007) Drug Metab Dispos , vol.35 , pp. 1333-1340
    • Hilgendorf, C.1    Ahlin, G.2    Seithel, A.3    Artursson, P.4    Ungell, A.L.5    Karlsson, J.6
  • 5
    • 62649085032 scopus 로고    scopus 로고
    • Variability in response to medicines in older people: Phenotypic and genotypic factors
    • McLachlan AJ, Hilmer SN, Le Couteur DG. Variability in response to medicines in older people: phenotypic and genotypic factors. Clin Pharmacol Ther. 2009;85:431-3.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 431-433
    • McLachlan, A.J.1    Hilmer, S.N.2    Le Couteur, D.G.3
  • 6
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson GR. Drug metabolism and variability among patients in drug response. N Engl J Med. 2005;352:2211-21.
    • (2005) N Engl J Med , vol.352 , pp. 2211-2221
    • Wilkinson, G.R.1
  • 7
    • 84890442900 scopus 로고    scopus 로고
    • Sex differences in the expression of drug-metabolizing and transporter genes in human liver
    • Yang L, Hong H, Chang C-W, Guo L-W, Lyn-Cook B, Shi L, et al. Sex differences in the expression of drug-metabolizing and transporter genes in human liver. J Metab Toxicol. 2012;3:1-9.
    • (2012) J Metab Toxicol , vol.3 , pp. 1-9
    • Yang, L.1    Hong, H.2    Chang, C.-W.3    Guo, L.-W.4    Lyn-Cook, B.5    Shi, L.6
  • 8
    • 84876541448 scopus 로고    scopus 로고
    • Gene expression variability in human hepatic drug metabolizing enzymes and transporters
    • Yang L, Price ET, Chang CW, Li Y, Huang Y, Guo LW, et al. Gene expression variability in human hepatic drug metabolizing enzymes and transporters. PLoS One. 2013;8:e60368.
    • (2013) PLoS One , vol.8 , pp. e60368
    • Yang, L.1    Price, E.T.2    Chang, C.W.3    Li, Y.4    Huang, Y.5    Guo, L.W.6
  • 9
    • 78649493404 scopus 로고    scopus 로고
    • Age and sex dependent changes in liver gene expression during the life cycle of the rat
    • Kwekel JC, Desai VG, Moland CL, Branham WS, Fuscoe JC. Age and sex dependent changes in liver gene expression during the life cycle of the rat. BMC Genomics. 2010;11:675.
    • (2010) BMC Genomics , vol.11 , pp. 675
    • Kwekel, J.C.1    Desai, V.G.2    Moland, C.L.3    Branham, W.S.4    Fuscoe, J.C.5
  • 12
    • 0032731634 scopus 로고    scopus 로고
    • Gender-related differences in pharmacokinetics and their clinical significance
    • Tanaka E. Gender-related differences in pharmacokinetics and their clinical significance. J Clin Pharm Ther. 1999;24:339-46.
    • (1999) J Clin Pharm Ther , vol.24 , pp. 339-346
    • Tanaka, E.1
  • 13
    • 0034919369 scopus 로고    scopus 로고
    • Exploring the biological contributions to human health: Does sex matter?
    • Committee on Understanding the Biology of Sex and Gender Differences. Exploring the biological contributions to human health: does sex matter? J Womens Health Gend Based Med. 2001;10:433-9.
    • (2001) J Womens Health Gend Based Med , vol.10 , pp. 433-439
  • 15
    • 0016222511 scopus 로고
    • Adverse drug reaction in the elderly
    • Hall MR. Adverse drug reaction in the elderly. Gerontol Clin (Basel). 1974;16:144-50.
    • (1974) Gerontol Clin (Basel) , vol.16 , pp. 144-150
    • Hall, M.R.1
  • 19
    • 33646246978 scopus 로고    scopus 로고
    • Effect of concurrent medications on cisplatin-induced nephrotoxicity in patients with head and neck cancer
    • Shord SS, Thompson DM, Krempl GA, Hanigan MH. Effect of concurrent medications on cisplatin-induced nephrotoxicity in patients with head and neck cancer. Anticancer Drugs. 2006;17:207-15.
    • (2006) Anticancer Drugs , vol.17 , pp. 207-215
    • Shord, S.S.1    Thompson, D.M.2    Krempl, G.A.3    Hanigan, M.H.4
  • 20
    • 77955082077 scopus 로고    scopus 로고
    • Genetic variation in metabolizing enzyme and transporter genes: Comprehensive assessment in 3 major East Asian subpopulations with comparison to Caucasians and Africans
    • Man M, Farmen M, Dumaual C, Teng CH, Moser B, Irie S, et al. Genetic variation in metabolizing enzyme and transporter genes: comprehensive assessment in 3 major East Asian subpopulations with comparison to Caucasians and Africans. J Clin Pharmacol. 2010;50:929-40.
    • (2010) J Clin Pharmacol , vol.50 , pp. 929-940
    • Man, M.1    Farmen, M.2    Dumaual, C.3    Teng, C.H.4    Moser, B.5    Irie, S.6
  • 21
    • 33747090656 scopus 로고    scopus 로고
    • Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: Comparison between human segments and Caco-2 cells
    • Seithel A, Karlsson J, Hilgendorf C, Bjorquist A, Ungell AL. Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cells. Eur J Pharm Sci. 2006;28:291-9.
    • (2006) Eur J Pharm Sci , vol.28 , pp. 291-299
    • Seithel, A.1    Karlsson, J.2    Hilgendorf, C.3    Bjorquist, A.4    Ungell, A.L.5
  • 23
    • 84901652491 scopus 로고    scopus 로고
    • Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: Critical reassessment of YBX3/ZONAB/CSDA expression
    • Dupasquier S, Delmarcelle AS, Marbaix E, Cosyns JP, Courtoy PJ, Pierreux CE. Validation of housekeeping gene and impact on normalized gene expression in clear cell renal cell carcinoma: critical reassessment of YBX3/ZONAB/CSDA expression. BMC Mol Biol. 2014;15:9.
    • (2014) BMC Mol Biol , vol.15 , pp. 9
    • Dupasquier, S.1    Delmarcelle, A.S.2    Marbaix, E.3    Cosyns, J.P.4    Courtoy, P.J.5    Pierreux, C.E.6
  • 24
    • 0037792045 scopus 로고    scopus 로고
    • Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies
    • Schmid H, Cohen CD, Henger A, Irrgang S, Schlondorff D, Kretzler M. Validation of endogenous controls for gene expression analysis in microdissected human renal biopsies. Kidney Int. 2003;64:356-60.
    • (2003) Kidney Int , vol.64 , pp. 356-360
    • Schmid, H.1    Cohen, C.D.2    Henger, A.3    Irrgang, S.4    Schlondorff, D.5    Kretzler, M.6
  • 25
    • 0030746213 scopus 로고    scopus 로고
    • Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology
    • Sirover MA. Role of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in normal cell function and in cell pathology. J Cell Biochem. 1997;66:133-40.
    • (1997) J Cell Biochem , vol.66 , pp. 133-140
    • Sirover, M.A.1
  • 26
    • 34147116274 scopus 로고    scopus 로고
    • Pitfalls in the normalization of real-time polymerase chain reaction data
    • Hendriks-Balk MC, Michel MC, Alewijnse AE. Pitfalls in the normalization of real-time polymerase chain reaction data. Basic Res Cardiol. 2007;102:195-7.
    • (2007) Basic Res Cardiol , vol.102 , pp. 195-197
    • Hendriks-Balk, M.C.1    Michel, M.C.2    Alewijnse, A.E.3
  • 27
    • 67650930085 scopus 로고    scopus 로고
    • Normalization of qRT-PCR data: The necessity of adopting a systematic, experimental conditions-specific, validation of references
    • Guenin S, Mauriat M, Pelloux J, Van Wuytswinkel O, Bellini C, Gutierrez L. Normalization of qRT-PCR data: the necessity of adopting a systematic, experimental conditions-specific, validation of references. J Exp Bot. 2009;60:487-93.
    • (2009) J Exp Bot , vol.60 , pp. 487-493
    • Guenin, S.1    Mauriat, M.2    Pelloux, J.3    Van Wuytswinkel, O.4    Bellini, C.5    Gutierrez, L.6
  • 28
    • 0034235250 scopus 로고    scopus 로고
    • Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction
    • Vila MR, Nicolas A, Morote J, de I, Meseguer A. Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction. Cancer. 2000;89:152-64.
    • (2000) Cancer , vol.89 , pp. 152-164
    • Vila, M.R.1    Nicolas, A.2    Morote, J.3    De, I.4    Meseguer, A.5
  • 31
    • 0027198854 scopus 로고
    • Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells
    • Mansur NR, Meyer-Siegler K, Wurzer JC, Sirover MA. Cell cycle regulation of the glyceraldehyde-3-phosphate dehydrogenase/uracil DNA glycosylase gene in normal human cells. Nucleic Acids Res. 1993;21:993-8.
    • (1993) Nucleic Acids Res , vol.21 , pp. 993-998
    • Mansur, N.R.1    Meyer-Siegler, K.2    Wurzer, J.C.3    Sirover, M.A.4
  • 33
    • 84865155360 scopus 로고    scopus 로고
    • Avoiding pitfalls of internal controls: Validation of reference genes for analysis by qRT-PCR and Western blot throughout rat retinal development
    • Rocha-Martins M, Njaine B, Silveira MS. Avoiding pitfalls of internal controls: validation of reference genes for analysis by qRT-PCR and Western blot throughout rat retinal development. PLoS One. 2012;7:e43028.
    • (2012) PLoS One , vol.7 , pp. e43028
    • Rocha-Martins, M.1    Njaine, B.2    Silveira, M.S.3
  • 34
    • 34548491164 scopus 로고    scopus 로고
    • Actin, a reliable marker of internal control?
    • Ruan W, Lai M. Actin, a reliable marker of internal control? Clin Chim Acta. 2007;385:1-5.
    • (2007) Clin Chim Acta , vol.385 , pp. 1-5
    • Ruan, W.1    Lai, M.2
  • 35
    • 71949087143 scopus 로고    scopus 로고
    • Scientific and regulatory perspectives on metabolizing enzyme-transporter interplay and its role in drug interactions: Challenges in predicting drug interactions
    • Zhang L, Zhang Y, Huang SM. Scientific and regulatory perspectives on metabolizing enzyme-transporter interplay and its role in drug interactions: challenges in predicting drug interactions. Mol Pharm. 2009;6:1766-74.
    • (2009) Mol Pharm , vol.6 , pp. 1766-1774
    • Zhang, L.1    Zhang, Y.2    Huang, S.M.3
  • 36
    • 79960771381 scopus 로고    scopus 로고
    • Transporter-mediated drug-drug interactions
    • Muller F, Fromm MF. Transporter-mediated drug-drug interactions. Pharmacogenomics. 2011;12:1017-37.
    • (2011) Pharmacogenomics , vol.12 , pp. 1017-1037
    • Muller, F.1    Fromm, M.F.2
  • 37
    • 84858212384 scopus 로고    scopus 로고
    • Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats
    • Al-Rejaie SS, Abuohashish HM, Alkhamees OA, Aleisa AM, Alroujayee AS. Gender difference following high cholesterol diet induced renal injury and the protective role of rutin and ascorbic acid combination in Wistar albino rats. Lipids Health Dis. 2012;11:41.
    • (2012) Lipids Health Dis , vol.11 , pp. 41
    • Al-Rejaie, S.S.1    Abuohashish, H.M.2    Alkhamees, O.A.3    Aleisa, A.M.4    Alroujayee, A.S.5
  • 38
    • 84878638336 scopus 로고    scopus 로고
    • Gender related differences in kidney injury induced by mercury
    • Hazelhoff MH, Bulacio RP, Torres AM. Gender related differences in kidney injury induced by mercury. Int J Mol Sci. 2012;13:10523-36.
    • (2012) Int J Mol Sci , vol.13 , pp. 10523-10536
    • Hazelhoff, M.H.1    Bulacio, R.P.2    Torres, A.M.3
  • 40
    • 41449083289 scopus 로고    scopus 로고
    • Gender and human chronic renal disease
    • Silbiger S, Neugarten J. Gender and human chronic renal disease. Gend Med. 2008;5(Suppl A):S3-S10.
    • (2008) Gend Med , vol.5 , pp. S3-S10
    • Silbiger, S.1    Neugarten, J.2
  • 41
    • 12344276521 scopus 로고    scopus 로고
    • HAART-related nephropathies in HIV-infected patients
    • Daugas E, Rougier JP, Hill G. HAART-related nephropathies in HIV-infected patients. Kidney Int. 2005;67:393-403.
    • (2005) Kidney Int , vol.67 , pp. 393-403
    • Daugas, E.1    Rougier, J.P.2    Hill, G.3
  • 42
    • 67649421634 scopus 로고    scopus 로고
    • Adverse drug reactions in elderly: Challenges in identification and improving preventative strategies
    • Tangiisuran B, Wright J, Van der Cammen T, Rajkumar C. Adverse drug reactions in elderly: challenges in identification and improving preventative strategies. Age Ageing. 2009;38:358-9.
    • (2009) Age Ageing , vol.38 , pp. 358-359
    • Tangiisuran, B.1    Wright, J.2    Van Der Cammen, T.3    Rajkumar, C.4
  • 44
    • 77953798742 scopus 로고    scopus 로고
    • Energy restriction does not compensate for the reduced expression of hepatic drug-processing genes in mice with aging
    • Zhang YK, Saupe KW, Klaassen CD. Energy restriction does not compensate for the reduced expression of hepatic drug-processing genes in mice with aging. Drug Metab Dispos. 2010;38:1122-31.
    • (2010) Drug Metab Dispos , vol.38 , pp. 1122-1131
    • Zhang, Y.K.1    Saupe, K.W.2    Klaassen, C.D.3
  • 45
    • 79959313678 scopus 로고    scopus 로고
    • Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney
    • Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. Functional maturation of drug transporters in the developing, neonatal, and postnatal kidney. Mol Pharmacol. 2011;80:147-54.
    • (2011) Mol Pharmacol , vol.80 , pp. 147-154
    • Sweeney, D.E.1    Vallon, V.2    Rieg, T.3    Wu, W.4    Gallegos, T.F.5    Nigam, S.K.6
  • 46
    • 0034990298 scopus 로고    scopus 로고
    • Estrogen-induced cardiorenal protection: Potential cellular, biochemical, and molecular mechanisms
    • Dubey RK, Jackson EK. Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms. Am J Physiol Renal Physiol. 2001;280:F365-388.
    • (2001) Am J Physiol Renal Physiol , vol.280 , pp. F365-F388
    • Dubey, R.K.1    Jackson, E.K.2
  • 48
    • 0034932889 scopus 로고    scopus 로고
    • Gender-based differences in the toxicity of pharmaceuticals - The Food and Drug Administration's perspective
    • Miller MA. Gender-based differences in the toxicity of pharmaceuticals - the Food and Drug Administration's perspective. Int J Toxicol. 2001;20:149-52.
    • (2001) Int J Toxicol , vol.20 , pp. 149-152
    • Miller, M.A.1
  • 49
    • 84886087870 scopus 로고    scopus 로고
    • In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: An intracerebral microdialysis study
    • Chan GN, Saldivia V, Yang Y, Pang H, de Lannoy I, Bendayan R. In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study. J Neurochem. 2013;127:342-52.
    • (2013) J Neurochem , vol.127 , pp. 342-352
    • Chan, G.N.1    Saldivia, V.2    Yang, Y.3    Pang, H.4    De Lannoy, I.5    Bendayan, R.6
  • 50
    • 49949090275 scopus 로고    scopus 로고
    • The role of ethnicity in variability in response to drugs: Focus on clinical pharmacology studies
    • Yasuda SU, Zhang L, Huang SM. The role of ethnicity in variability in response to drugs: focus on clinical pharmacology studies. Clin Pharmacol Ther. 2008;84:417-23.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 417-423
    • Yasuda, S.U.1    Zhang, L.2    Huang, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.