Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane

Genes and Development

Volumn 30, Issue 8, 2016, Pages 973-988

  O’neill, Katelyn L ^a   Huang, Kai ^a   Zhang, Jingjing ^a,b   Chen, Yi ^a   Luo, Xu ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Anti apoptotic Bcl 2 proteins; Bax Bak activation; BH3 only; Outer mitochondrial membrane

Indexed keywords

PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; MCL1 PROTEIN, HUMAN; PROTEIN MCL 1;

APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; OLIGOMERIZATION; OUTER MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; ANIMAL; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HCT 116 CELL LINE; HELA CELL LINE; METABOLISM; MOUSE;

ANIMALS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; HCT116 CELLS; HELA CELLS; HUMANS; MICE; MITOCHONDRIAL MEMBRANES; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84963864250     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.276725.115     Document Type: Article

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