BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 23, 2015, Pages 7201-7206

  Carpio, Marcos A ^a   Michaud, Michael ^a   Zhou, Wenping ^a   Fisher, Jill K ^b   Walensky, Loren D ^b   Katz, Samuel G ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; BCL 2 family; BOK; Endoplasmic reticulum stress; Unfolded protein response

Indexed keywords

B CELL LYMPHOMA 2 OVARIAN KILLER PROTEIN; BORTEZOMIB; BREFELDIN A; CALCIMYCIN; DITHIOTHREITOL; ETOPOSIDE; GELDANAMYCIN; PROTEIN BCL 2; STAUROSPORINE; THAPSIGARGIN; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, MOUSE; BOK PROTEIN, MOUSE; CASPASE 3; CASPASE 7; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; LIPOCORTIN 5;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BOK GENE; CELLULAR DISTRIBUTION; ENDOPLASMIC RETICULUM STRESS; FIBROBLAST; GENE; IN VIVO STUDY; MITOCHONDRION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REGULATORY MECHANISM; ULTRAVIOLET RADIATION; ANIMAL; CELL CULTURE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; OXIDATIVE STRESS; PHYSIOLOGY;

MUS;

ACTIVATING TRANSCRIPTION FACTOR 4; ANIMALS; ANNEXIN A5; APOPTOSIS; CASPASE 3; CASPASE 7; CELLS, CULTURED; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; MICE; MICE, KNOCKOUT; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSCRIPTION FACTOR CHOP;

EID: 84931275602     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421063112     Document Type: Article

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