Perturbation of the Bcl-2 network and an induced Noxa/Bcl-xL interaction trigger mitochondrial dysfunction after DNA damage

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 15016-15026

  Lopez, Hernando ^a   Zhang, Liqiang ^a   George, Nicholas M ^a   Liu, Xiaoqiong ^a   Pang, Xiaming ^a   Evans, Jacquelynn J D ^a   Targy, Natalie M ^a   Luo, Xu ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; APOPTOTIC STIMULI; CAMPTOTHECINS; CYTOCHROME C; DEATH-RECEPTOR; DNA DAMAGES; DNA DAMAGING AGENTS; EXPRESSION SYSTEM; HELA CELL; INDUCED APOPTOSIS; INDUCED INTERACTION; MITOCHONDRIAL DYSFUNCTION;

CELL DEATH; DNA; PROTEINS;

GENES;

BH3 PROTEIN; BIM PROTEIN; CYTOCHROME C; DNA; PROTEIN BAD; PROTEIN BAK; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN MCL 1; PROTEIN NOXA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ENZYME RELEASE; HELA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION;

APOPTOSIS; BCL-X PROTEIN; CAMPTOTHECIN; CELL LINE; CYTOCHROMES C; DNA DAMAGE; HELA CELLS; HUMANS; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 77952029788     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.086231     Document Type: Article

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