Conformational rearrangements in the pro-apoptotic protein, bax, as it inserts into mitochondria: A cellular death switch

Journal of Biological Chemistry

Volumn 289, Issue 47, 2014, Pages 32871-32882

  Gahl, Robert F ^a   He, Yi ^a   Yu, Shiqin ^a   Tjandra, Nico ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CELL MEMBRANES; CONFORMATIONS; ENERGY TRANSFER; FLUORESCENCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEINS;

COMPLEX FORMATIONS; CONFORMATIONAL CHANGE; FLUORESCENCE CORRELATION SPECTROSCOPY; MOLECULAR CONTACTS; MOLECULAR SIGNATURES; OUTER MITOCHONDRIAL MEMBRANES; RESONANCE ENERGY TRANSFER; TRANSIENT MEMBRANE;

MITOCHONDRIA;

BH3 PROTEIN; CYTOCHROME C; PROTEIN BAX; 4 DIMETHYLAMINOAZOBENZENE; 4-(4-DIMETHYLAMINOPHENYLAZO)BENZOIC ACID; ALEXA FLUOR 546; QUINOLINE DERIVATIVE; STAUROSPORINE;

ALPHA HELIX; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DEATH; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CROSS LINKING; CYTOSOL; FLUORESCENCE CORRELATION SPECTROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; IMAGE ANALYSIS; MITOCHONDRION; OUTER MEMBRANE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; ANALOGS AND DERIVATIVES; ANIMAL; ANIMAL EMBRYO; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; GENETICS; METABOLISM; MOUSE; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TRANSPORT; SPECTROFLUOROMETRY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELLS, CULTURED; CYTOSOL; EMBRYO, MAMMALIAN; FIBROBLASTS; FLUORESCENCE RESONANCE ENERGY TRANSFER; MICE; MITOCHONDRIA; MODELS, MOLECULAR; MUTATION; P-DIMETHYLAMINOAZOBENZENE; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN TRANSPORT; QUINOLINIUM COMPOUNDS; SPECTROMETRY, FLUORESCENCE; STAUROSPORINE;

EID: 84911412568     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.593897     Document Type: Article

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