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Volumn 111, Issue 3, 2016, Pages

Myocardial apoptosis in heart disease: does the emperor have clothes?

Author keywords

Apoptosis; Heart failure; Myocardial infarction; Myocytes; Necrosis; Non myocyte

Indexed keywords

APOPTOSIS; ENDOTHELIUM CELL; HEART FAILURE; HEART FIBROBLAST; HEART INFARCTION; HEART MUSCLE CELL; HUMAN; MACROPHAGE; MONOCYTE; MYOFIBROBLAST; NEUTROPHIL; NONHUMAN; REVIEW; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CYTOLOGY; HEART DISEASE; PATHOLOGY; PHYSIOLOGY;

EID: 84962643295     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-016-0549-2     Document Type: Review
Times cited : (76)

References (132)
  • 3
    • 0037049990 scopus 로고    scopus 로고
    • Myocyte renewal and ventricular remodelling
    • COI: 1:CAS:528:DC%2BD38Xms1WgtQ%3D%3D, PID: 11805849
    • Anversa P, Nadal-Ginard B (2002) Myocyte renewal and ventricular remodelling. Nature 415:240–243. doi:10.1038/415240a
    • (2002) Nature , vol.415 , pp. 240-243
    • Anversa, P.1    Nadal-Ginard, B.2
  • 5
    • 33747357533 scopus 로고    scopus 로고
    • Switch from caspase-dependent to caspase-independent death during heart development: essential role of endonuclease G in ischemia-induced DNA processing of differentiated cardiomyocytes
    • COI: 1:CAS:528:DC%2BD28XnvVWjtro%3D, PID: 16754658
    • Bahi N, Zhang J, Llovera M, Ballester M, Comella JX, Sanchis D (2006) Switch from caspase-dependent to caspase-independent death during heart development: essential role of endonuclease G in ischemia-induced DNA processing of differentiated cardiomyocytes. J Biol Chem 281:22943–22952. doi:10.1074/jbc.M601025200
    • (2006) J Biol Chem , vol.281 , pp. 22943-22952
    • Bahi, N.1    Zhang, J.2    Llovera, M.3    Ballester, M.4    Comella, J.X.5    Sanchis, D.6
  • 7
    • 0033587530 scopus 로고    scopus 로고
    • Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production
    • COI: 1:CAS:528:DyaK1MXltVOht7o%3D, PID: 10411855
    • Bauersachs J, Bouloumie A, Fraccarollo D, Hu K, Busse R, Ertl G (1999) Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production. Circulation 100:292–298
    • (1999) Circulation , vol.100 , pp. 292-298
    • Bauersachs, J.1    Bouloumie, A.2    Fraccarollo, D.3    Hu, K.4    Busse, R.5    Ertl, G.6
  • 8
    • 79955031839 scopus 로고    scopus 로고
    • Fibroblasts and myofibroblasts: what are we talking about?
    • COI: 1:CAS:528:DC%2BC3MXks1WhsL8%3D, PID: 21297493
    • Baum J, Duffy HS (2011) Fibroblasts and myofibroblasts: what are we talking about? J Cardiovasc Pharmacol 57:376–379. doi:10.1097/FJC.0b013e3182116e39
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 376-379
    • Baum, J.1    Duffy, H.S.2
  • 9
    • 0035997536 scopus 로고    scopus 로고
    • The neutrophil as a mediator of myocardial ischemia-reperfusion injury: time to move on
    • PID: 12111036
    • Baxter GF (2002) The neutrophil as a mediator of myocardial ischemia-reperfusion injury: time to move on. Basic Res Cardiol 97:268–275. doi:10.1007/s00395-002-0366-7
    • (2002) Basic Res Cardiol , vol.97 , pp. 268-275
    • Baxter, G.F.1
  • 11
    • 0024416745 scopus 로고
    • Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis
    • COI: 1:CAS:528:DyaL1MXlsFWgurw%3D, PID: 2527639
    • Benjamin IJ, Jalil JE, Tan LB, Cho K, Weber KT, Clark WA (1989) Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. Circ Res 65:657–670
    • (1989) Circ Res , vol.65 , pp. 657-670
    • Benjamin, I.J.1    Jalil, J.E.2    Tan, L.B.3    Cho, K.4    Weber, K.T.5    Clark, W.A.6
  • 13
    • 0030819138 scopus 로고    scopus 로고
    • Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
    • COI: 1:CAS:528:DyaK2sXmt1Cqs7c%3D, PID: 9294101
    • Bialik S, Geenen DL, Sasson IE, Cheng R, Horner JW, Evans SM, Lord EM, Koch CJ, Kitsis RN (1997) Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Investig 100:1363–1372. doi:10.1172/JCI119656
    • (1997) J Clin Investig , vol.100 , pp. 1363-1372
    • Bialik, S.1    Geenen, D.L.2    Sasson, I.E.3    Cheng, R.4    Horner, J.W.5    Evans, S.M.6    Lord, E.M.7    Koch, C.J.8    Kitsis, R.N.9
  • 14
    • 0027967047 scopus 로고
    • Hypothesis: apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload
    • COI: 1:CAS:528:DyaK2cXlslKgsrk%3D, PID: 7799449
    • Bing OH (1994) Hypothesis: apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload. J Mol Cell Cardiol 26:943–948. doi:10.1006/jmcc.1994.1115
    • (1994) J Mol Cell Cardiol , vol.26 , pp. 943-948
    • Bing, O.H.1
  • 15
    • 0037207468 scopus 로고    scopus 로고
    • Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity
    • COI: 1:CAS:528:DC%2BD3sXntlGgsw%3D%3D, PID: 12506127
    • Brutsaert DL (2003) Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity. Physiol Rev 83:59–115. doi:10.1152/physrev.00017.2002
    • (2003) Physiol Rev , vol.83 , pp. 59-115
    • Brutsaert, D.L.1
  • 16
    • 33749513188 scopus 로고    scopus 로고
    • Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy
    • COI: 1:CAS:528:DC%2BD28XhtVyit7jI, PID: 17045908
    • Cai L, Wang Y, Zhou G, Chen T, Song Y, Li X, Kang YJ (2006) Attenuation by metallothionein of early cardiac cell death via suppression of mitochondrial oxidative stress results in a prevention of diabetic cardiomyopathy. J Am Coll Cardiol 48:1688–1697. doi:10.1016/j.jacc.2006.07.022
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1688-1697
    • Cai, L.1    Wang, Y.2    Zhou, G.3    Chen, T.4    Song, Y.5    Li, X.6    Kang, Y.J.7
  • 17
    • 1242336980 scopus 로고    scopus 로고
    • Apoptosis: the nexus of liver injury and fibrosis
    • PID: 14767974
    • Canbay A, Friedman S, Gores GJ (2004) Apoptosis: the nexus of liver injury and fibrosis. Hepatology 39:273–278. doi:10.1002/hep.20051
    • (2004) Hepatology , vol.39 , pp. 273-278
    • Canbay, A.1    Friedman, S.2    Gores, G.J.3
  • 18
    • 0035800882 scopus 로고    scopus 로고
    • Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy
    • COI: 1:CAS:528:DC%2BD3MXmt1ClsbY%3D, PID: 11485979
    • Cesselli D, Jakoniuk I, Barlucchi L, Beltrami AP, Hintze TH, Nadal-Ginard B, Kajstura J, Leri A, Anversa P (2001) Oxidative stress-mediated cardiac cell death is a major determinant of ventricular dysfunction and failure in dog dilated cardiomyopathy. Circ Res 89:279–286
    • (2001) Circ Res , vol.89 , pp. 279-286
    • Cesselli, D.1    Jakoniuk, I.2    Barlucchi, L.3    Beltrami, A.P.4    Hintze, T.H.5    Nadal-Ginard, B.6    Kajstura, J.7    Leri, A.8    Anversa, P.9
  • 19
    • 1042299088 scopus 로고    scopus 로고
    • Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction
    • COI: 1:CAS:528:DC%2BD2cXitVynsLs%3D, PID: 14736452
    • Chandrashekhar Y, Sen S, Anway R, Shuros A, Anand I (2004) Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction. J Am Coll Cardiol 43:295–301
    • (2004) J Am Coll Cardiol , vol.43 , pp. 295-301
    • Chandrashekhar, Y.1    Sen, S.2    Anway, R.3    Shuros, A.4    Anand, I.5
  • 20
    • 0023224848 scopus 로고
    • Neutrophil accumulation in experimental myocardial infarcts: relation with extent of injury and effect of reperfusion
    • COI: 1:STN:280:DyaL2s7ovVWntg%3D%3D, PID: 3568308
    • Chatelain P, Latour JG, Tran D, de Lorgeril M, Dupras G, Bourassa M (1987) Neutrophil accumulation in experimental myocardial infarcts: relation with extent of injury and effect of reperfusion. Circulation 75:1083–1090
    • (1987) Circulation , vol.75 , pp. 1083-1090
    • Chatelain, P.1    Latour, J.G.2    Tran, D.3    de Lorgeril, M.4    Dupras, G.5    Bourassa, M.6
  • 21
    • 79958029159 scopus 로고    scopus 로고
    • Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload
    • COI: 1:CAS:528:DC%2BC3MXot1Grsr0%3D, PID: 21421827
    • Chen YW, Pat B, Gladden JD, Zheng J, Powell P, Wei CC, Cui X, Husain A, Dell’italia LJ (2011) Dynamic molecular and histopathological changes in the extracellular matrix and inflammation in the transition to heart failure in isolated volume overload. Am J Physiol Heart Circ Physiol 300:H2251–H2260. doi:10.1152/ajpheart.01104.2010
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H2251-H2260
    • Chen, Y.W.1    Pat, B.2    Gladden, J.D.3    Zheng, J.4    Powell, P.5    Wei, C.C.6    Cui, X.7    Husain, A.8    Dell’italia, L.J.9
  • 24
    • 77249085646 scopus 로고    scopus 로고
    • Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation
    • COI: 1:CAS:528:DC%2BC3cXit1aksLg%3D, PID: 20133797
    • Cohen I, Rider P, Carmi Y, Braiman A, Dotan S, White MR, Voronov E, Martin MU, Dinarello CA, Apte RN (2010) Differential release of chromatin-bound IL-1alpha discriminates between necrotic and apoptotic cell death by the ability to induce sterile inflammation. Proc Natl Acad Sci USA 107:2574–2579. doi:10.1073/pnas.0915018107
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 2574-2579
    • Cohen, I.1    Rider, P.2    Carmi, Y.3    Braiman, A.4    Dotan, S.5    White, M.R.6    Voronov, E.7    Martin, M.U.8    Dinarello, C.A.9    Apte, R.N.10
  • 26
    • 67649595826 scopus 로고    scopus 로고
    • Apoptosis and cancer: the genesis of a research field
    • COI: 1:CAS:528:DC%2BD1MXnsFynt74%3D, PID: 19550425
    • Cotter TG (2009) Apoptosis and cancer: the genesis of a research field. Nat Rev Cancer 9:501–507. doi:10.1038/nrc2663
    • (2009) Nat Rev Cancer , vol.9 , pp. 501-507
    • Cotter, T.G.1
  • 27
    • 0022501688 scopus 로고
    • Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells
    • COI: 1:CAS:528:DyaL28XlvVyktbs%3D, PID: 3745437
    • Cronstein BN, Levin RI, Belanoff J, Weissmann G, Hirschhorn R (1986) Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells. J Clin Investig 78:760–770. doi:10.1172/JCI112638
    • (1986) J Clin Investig , vol.78 , pp. 760-770
    • Cronstein, B.N.1    Levin, R.I.2    Belanoff, J.3    Weissmann, G.4    Hirschhorn, R.5
  • 28
    • 8844235617 scopus 로고    scopus 로고
    • The mitochondrial death pathway and cardiac myocyte apoptosis
    • COI: 1:CAS:528:DC%2BD2cXpt1GhsLc%3D, PID: 15539639
    • Crow MT, Mani K, Nam YJ, Kitsis RN (2004) The mitochondrial death pathway and cardiac myocyte apoptosis. Circ Res 95:957–970. doi:10.1161/01.RES.0000148632.35500.d9
    • (2004) Circ Res , vol.95 , pp. 957-970
    • Crow, M.T.1    Mani, K.2    Nam, Y.J.3    Kitsis, R.N.4
  • 29
    • 79957888573 scopus 로고    scopus 로고
    • Mechanisms of HIV-associated lymphocyte apoptosis: 2010
    • COI: 1:STN:280:DC%2BC3M3jsVWnsQ%3D%3D, PID: 21368875
    • Cummins NW, Badley AD (2010) Mechanisms of HIV-associated lymphocyte apoptosis: 2010. Cell Death Dis 1:e99. doi:10.1038/cddis.2010.77
    • (2010) Cell Death Dis , vol.1 , pp. e99
    • Cummins, N.W.1    Badley, A.D.2
  • 30
    • 85047679273 scopus 로고
    • Endogenous chemical mediators of ventricular arrhythmias in ischaemic heart disease
    • COI: 1:CAS:528:DyaK3sXmtVSlu7w%3D, PID: 8348568
    • Curtis MJ, Pugsley MK, Walker MJ (1993) Endogenous chemical mediators of ventricular arrhythmias in ischaemic heart disease. Cardiovasc Res 27:703–719
    • (1993) Cardiovasc Res , vol.27 , pp. 703-719
    • Curtis, M.J.1    Pugsley, M.K.2    Walker, M.J.3
  • 31
    • 38349127082 scopus 로고    scopus 로고
    • Nix: the cardiac Styx between life and death
    • PID: 18212298
    • da Costa Martins PA, De Windt LJ (2008) Nix: the cardiac Styx between life and death. Circulation 117:338–340. doi:10.1161/CIRCULATIONAHA.107.750125
    • (2008) Circulation , vol.117 , pp. 338-340
    • da Costa Martins, P.A.1    De Windt, L.J.2
  • 32
    • 34247598856 scopus 로고    scopus 로고
    • Endothelial mitochondria: contributing to vascular function and disease
    • COI: 1:CAS:528:DC%2BD2sXktlOhsrY%3D, PID: 17463328
    • Davidson SM, Duchen MR (2007) Endothelial mitochondria: contributing to vascular function and disease. Circ Res 100:1128–1141. doi:10.1161/01.RES.0000261970.18328.1d
    • (2007) Circ Res , vol.100 , pp. 1128-1141
    • Davidson, S.M.1    Duchen, M.R.2
  • 33
    • 0033959317 scopus 로고    scopus 로고
    • Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes
    • COI: 1:CAS:528:DC%2BD3cXnsVWjsA%3D%3D, PID: 10652190
    • de Moissac D, Gurevich RM, Zheng H, Singal PK, Kirshenbaum LA (2000) Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes. J Mol Cell Cardiol 32:53–63. doi:10.1006/jmcc.1999.1057
    • (2000) J Mol Cell Cardiol , vol.32 , pp. 53-63
    • de Moissac, D.1    Gurevich, R.M.2    Zheng, H.3    Singal, P.K.4    Kirshenbaum, L.A.5
  • 34
    • 0028851160 scopus 로고
    • Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar
    • COI: 1:STN:280:DyaK2M7mtVWhsA%3D%3D, PID: 7856739
    • Desmouliere A, Redard M, Darby I, Gabbiani G (1995) Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 146:56–66
    • (1995) Am J Pathol , vol.146 , pp. 56-66
    • Desmouliere, A.1    Redard, M.2    Darby, I.3    Gabbiani, G.4
  • 35
    • 38349184844 scopus 로고    scopus 로고
    • Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation
    • COI: 1:CAS:528:DC%2BD1cXlvV2isw%3D%3D, PID: 18178777
    • Diwan A, Wansapura J, Syed FM, Matkovich SJ, Lorenz JN, Dorn GW 2nd (2008) Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation. Circulation 117:396–404. doi:10.1161/CIRCULATIONAHA.107.727073
    • (2008) Circulation , vol.117 , pp. 396-404
    • Diwan, A.1    Wansapura, J.2    Syed, F.M.3    Matkovich, S.J.4    Lorenz, J.N.5    Dorn, G.W.6
  • 36
    • 77649276038 scopus 로고    scopus 로고
    • The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction
    • COI: 1:CAS:528:DC%2BC3cXitVeju7o%3D, PID: 19631653
    • Dobaczewski M, Gonzalez-Quesada C, Frangogiannis NG (2010) The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol 48:504–511. doi:10.1016/j.yjmcc.2009.07.015
    • (2010) J Mol Cell Cardiol , vol.48 , pp. 504-511
    • Dobaczewski, M.1    Gonzalez-Quesada, C.2    Frangogiannis, N.G.3
  • 37
    • 84927633441 scopus 로고    scopus 로고
    • Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression
    • COI: 1:CAS:528:DC%2BC2cXhsFymur%2FF, PID: 24902966
    • Dong Q, Chen L, Lu Q, Sharma S, Li L, Morimoto S, Wang G (2014) Quercetin attenuates doxorubicin cardiotoxicity by modulating Bmi-1 expression. Br J Pharmacol 171:4440–4454. doi:10.1111/bph.12795
    • (2014) Br J Pharmacol , vol.171 , pp. 4440-4454
    • Dong, Q.1    Chen, L.2    Lu, Q.3    Sharma, S.4    Li, L.5    Morimoto, S.6    Wang, G.7
  • 39
    • 0033168594 scopus 로고    scopus 로고
    • Increased apoptosis in patients with major depression: a preliminary study
    • COI: 1:CAS:528:DyaK1MXktF2rtr4%3D, PID: 10384158, (ji_v163n1p533 [pii])
    • Eilat E, Mendlovic S, Doron A, Zakuth V, Spirer Z (1999) Increased apoptosis in patients with major depression: a preliminary study. J Immunol 163:533–534 (ji_v163n1p533 [pii])
    • (1999) J Immunol , vol.163 , pp. 533-534
    • Eilat, E.1    Mendlovic, S.2    Doron, A.3    Zakuth, V.4    Spirer, Z.5
  • 40
    • 0026445442 scopus 로고
    • Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence
    • COI: 1:CAS:528:DyaK3sXkvFaq, PID: 1357003
    • Entman ML, Youker K, Shoji T, Kukielka G, Shappell SB, Taylor AA, Smith CW (1992) Neutrophil induced oxidative injury of cardiac myocytes. A compartmented system requiring CD11b/CD18-ICAM-1 adherence. J Clin Investig 90:1335–1345. doi:10.1172/JCI115999
    • (1992) J Clin Investig , vol.90 , pp. 1335-1345
    • Entman, M.L.1    Youker, K.2    Shoji, T.3    Kukielka, G.4    Shappell, S.B.5    Taylor, A.A.6    Smith, C.W.7
  • 41
    • 84871620341 scopus 로고    scopus 로고
    • The diverse identity of angiogenic monocytes
    • PID: 23083351
    • Favre J, Terborg N, Horrevoets AJ (2013) The diverse identity of angiogenic monocytes. Eur J Clin Invest 43:100–107. doi:10.1111/eci.12009
    • (2013) Eur J Clin Invest , vol.43 , pp. 100-107
    • Favre, J.1    Terborg, N.2    Horrevoets, A.J.3
  • 43
    • 0029956792 scopus 로고    scopus 로고
    • Apoptosis in ischemic and reperfused rat myocardium
    • COI: 1:CAS:528:DyaK28XmsFGlsL8%3D, PID: 8888687
    • Fliss H, Gattinger D (1996) Apoptosis in ischemic and reperfused rat myocardium. Circ Res 79:949–956
    • (1996) Circ Res , vol.79 , pp. 949-956
    • Fliss, H.1    Gattinger, D.2
  • 45
    • 84899090049 scopus 로고    scopus 로고
    • Cardiac macrophages and their role in ischaemic heart disease
    • COI: 1:CAS:528:DC%2BC2cXmsVKhtr0%3D, PID: 24501331
    • Frantz S, Nahrendorf M (2014) Cardiac macrophages and their role in ischaemic heart disease. Cardiovasc Res 102:240–248. doi:10.1093/cvr/cvu025
    • (2014) Cardiovasc Res , vol.102 , pp. 240-248
    • Frantz, S.1    Nahrendorf, M.2
  • 47
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • COI: 1:CAS:528:DyaK38XmtVyhsbs%3D, PID: 1400587
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119:493–501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 48
    • 0027967063 scopus 로고
    • Reperfusion injury induces apoptosis in rabbit cardiomyocytes
    • COI: 1:STN:280:DyaK2M%2FhsFSgsA%3D%3D, PID: 7929838
    • Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL (1994) Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Investig 94:1621–1628. doi:10.1172/JCI117504
    • (1994) J Clin Investig , vol.94 , pp. 1621-1628
    • Gottlieb, R.A.1    Burleson, K.O.2    Kloner, R.A.3    Babior, B.M.4    Engler, R.L.5
  • 49
    • 0029885316 scopus 로고    scopus 로고
    • Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis
    • COI: 1:CAS:528:DyaK28Xjt12isLg%3D, PID: 8636421
    • Gottlieb RA, Gruol DL, Zhu JY, Engler RL (1996) Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis. J Clin Investig 97:2391–2398. doi:10.1172/JCI118683
    • (1996) J Clin Investig , vol.97 , pp. 2391-2398
    • Gottlieb, R.A.1    Gruol, D.L.2    Zhu, J.Y.3    Engler, R.L.4
  • 50
    • 21044445452 scopus 로고    scopus 로고
    • Apoptosis: a mechanism of acute and chronic liver injury
    • COI: 1:CAS:528:DC%2BD2MXmsFKqtrY%3D, PID: 15951554
    • Guicciardi ME, Gores GJ (2005) Apoptosis: a mechanism of acute and chronic liver injury. Gut 54:1024–1033. doi:10.1136/gut.2004.053850
    • (2005) Gut , vol.54 , pp. 1024-1033
    • Guicciardi, M.E.1    Gores, G.J.2
  • 53
    • 79952176105 scopus 로고    scopus 로고
    • Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair
    • COI: 1:CAS:528:DC%2BC3MXhslGrsbw%3D, PID: 21245355
    • Harel-Adar T, Ben Mordechai T, Amsalem Y, Feinberg MS, Leor J, Cohen S (2011) Modulation of cardiac macrophages by phosphatidylserine-presenting liposomes improves infarct repair. Proc Natl Acad Sci USA 108:1827–1832. doi:10.1073/pnas.1015623108
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 1827-1832
    • Harel-Adar, T.1    Ben Mordechai, T.2    Amsalem, Y.3    Feinberg, M.S.4    Leor, J.5    Cohen, S.6
  • 54
    • 79958794987 scopus 로고    scopus 로고
    • Apoptosis and acute kidney injury
    • COI: 1:CAS:528:DC%2BC3MXnsFKlsL0%3D, PID: 21562469
    • Havasi A, Borkan SC (2011) Apoptosis and acute kidney injury. Kidney Int 80:29–40. doi:10.1038/ki.2011.120
    • (2011) Kidney Int , vol.80 , pp. 29-40
    • Havasi, A.1    Borkan, S.C.2
  • 55
    • 0038502520 scopus 로고    scopus 로고
    • Inhibition of granulation tissue cell apoptosis during the subacute stage of myocardial infarction improves cardiac remodeling and dysfunction at the chronic stage
    • PID: 12821555
    • Hayakawa K, Takemura G, Kanoh M, Li Y, Koda M, Kawase Y, Maruyama R, Okada H, Minatoguchi S, Fujiwara T, Fujiwara H (2003) Inhibition of granulation tissue cell apoptosis during the subacute stage of myocardial infarction improves cardiac remodeling and dysfunction at the chronic stage. Circulation 108:104–109. doi:10.1161/01.CIR.0000074225.62168.68
    • (2003) Circulation , vol.108 , pp. 104-109
    • Hayakawa, K.1    Takemura, G.2    Kanoh, M.3    Li, Y.4    Koda, M.5    Kawase, Y.6    Maruyama, R.7    Okada, H.8    Minatoguchi, S.9    Fujiwara, T.10    Fujiwara, H.11
  • 56
    • 0037173093 scopus 로고    scopus 로고
    • Sensitivity to apoptosis signal, clearance rate, and ultrastructure of Fas ligand-induced apoptosis in in vivo adult cardiac cells
    • COI: 1:CAS:528:DC%2BD38XlslSjtrs%3D, PID: 12082000
    • Hayakawa K, Takemura G, Koda M, Kawase Y, Maruyama R, Li Y, Minatoguchi S, Fujiwara T, Fujiwara H (2002) Sensitivity to apoptosis signal, clearance rate, and ultrastructure of Fas ligand-induced apoptosis in in vivo adult cardiac cells. Circulation 105:3039–3045
    • (2002) Circulation , vol.105 , pp. 3039-3045
    • Hayakawa, K.1    Takemura, G.2    Koda, M.3    Kawase, Y.4    Maruyama, R.5    Li, Y.6    Minatoguchi, S.7    Fujiwara, T.8    Fujiwara, H.9
  • 59
    • 0029001622 scopus 로고
    • DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis
    • COI: 1:CAS:528:DyaK2MXms1Sku74%3D, PID: 7778672
    • Itoh G, Tamura J, Suzuki M, Suzuki Y, Ikeda H, Koike M, Nomura M, Jie T, Ito K (1995) DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis. Am J Pathol 146:1325–1331
    • (1995) Am J Pathol , vol.146 , pp. 1325-1331
    • Itoh, G.1    Tamura, J.2    Suzuki, M.3    Suzuki, Y.4    Ikeda, H.5    Koike, M.6    Nomura, M.7    Jie, T.8    Ito, K.9
  • 60
    • 84891818196 scopus 로고    scopus 로고
    • The role of monocytes in angiogenesis and atherosclerosis
    • COI: 1:CAS:528:DC%2BC2cXltVGjsw%3D%3D, PID: 24140662
    • Jaipersad AS, Lip GY, Silverman S, Shantsila E (2014) The role of monocytes in angiogenesis and atherosclerosis. J Am Coll Cardiol 63:1–11. doi:10.1016/j.jacc.2013.09.019
    • (2014) J Am Coll Cardiol , vol.63 , pp. 1-11
    • Jaipersad, A.S.1    Lip, G.Y.2    Silverman, S.3    Shantsila, E.4
  • 61
    • 0022519328 scopus 로고
    • Reduction of myocardial infarct size by neutrophil depletion: effect of duration of occlusion
    • COI: 1:STN:280:DyaL2s%2Fit1Oisw%3D%3D, PID: 3766367
    • Jolly SR, Kane WJ, Hook BG, Abrams GD, Kunkel SL, Lucchesi BR (1986) Reduction of myocardial infarct size by neutrophil depletion: effect of duration of occlusion. Am Heart J 112:682–690
    • (1986) Am Heart J , vol.112 , pp. 682-690
    • Jolly, S.R.1    Kane, W.J.2    Hook, B.G.3    Abrams, G.D.4    Kunkel, S.L.5    Lucchesi, B.R.6
  • 62
    • 0141653901 scopus 로고    scopus 로고
    • Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?
    • PID: 12975244
    • Jugdutt BI (2003) Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough? Circulation 108:1395–1403. doi:10.1161/01.CIR.0000085658.98621.49
    • (2003) Circulation , vol.108 , pp. 1395-1403
    • Jugdutt, B.I.1
  • 63
    • 84875214942 scopus 로고    scopus 로고
    • Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts
    • COI: 1:CAS:528:DC%2BC3sXjvFCjurs%3D, PID: 23392842
    • Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH (2013) Endoscopic time-lapse imaging of immune cells in infarcted mouse hearts. Circ Res 112:891–899. doi:10.1161/CIRCRESAHA.111.300484
    • (2013) Circ Res , vol.112 , pp. 891-899
    • Jung, K.1    Kim, P.2    Leuschner, F.3    Gorbatov, R.4    Kim, J.K.5    Ueno, T.6    Nahrendorf, M.7    Yun, S.H.8
  • 64
    • 3242743583 scopus 로고    scopus 로고
    • Targeted deletion of CC chemokine receptor 2 attenuates left ventricular remodeling after experimental myocardial infarction
    • COI: 1:CAS:528:DC%2BD2cXmvFSqu7g%3D, PID: 15277218
    • Kaikita K, Hayasaki T, Okuma T, Kuziel WA, Ogawa H, Takeya M (2004) Targeted deletion of CC chemokine receptor 2 attenuates left ventricular remodeling after experimental myocardial infarction. Am J Pathol 165:439–447. doi:10.1016/S0002-9440(10)63309-3
    • (2004) Am J Pathol , vol.165 , pp. 439-447
    • Kaikita, K.1    Hayasaki, T.2    Okuma, T.3    Kuziel, W.A.4    Ogawa, H.5    Takeya, M.6
  • 68
    • 0028582183 scopus 로고
    • Apoptosis in acute and chronic myocarditis
    • COI: 1:STN:280:DyaK2M3gsFGkug%3D%3D, PID: 7897820
    • Kawano H, Okada R, Kawano Y, Sueyoshi N, Shirai T (1994) Apoptosis in acute and chronic myocarditis. Jpn Heart J 35:745–750
    • (1994) Jpn Heart J , vol.35 , pp. 745-750
    • Kawano, H.1    Okada, R.2    Kawano, Y.3    Sueyoshi, N.4    Shirai, T.5
  • 69
  • 70
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • COI: 1:STN:280:DyaE3s%2FgsFSksw%3D%3D, PID: 4561027
    • Kerr JF, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239–257
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 71
    • 0035044085 scopus 로고    scopus 로고
    • Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    • COI: 1:CAS:528:DC%2BD3MXis1yls7s%3D, PID: 11283669
    • Kocher AA, Schuster MD, Szabolcs MJ, Takuma S, Burkhoff D, Wang J, Homma S, Edwards NM, Itescu S (2001) Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function. Nat Med 7:430–436. doi:10.1038/86498
    • (2001) Nat Med , vol.7 , pp. 430-436
    • Kocher, A.A.1    Schuster, M.D.2    Szabolcs, M.J.3    Takuma, S.4    Burkhoff, D.5    Wang, J.6    Homma, S.7    Edwards, N.M.8    Itescu, S.9
  • 72
    • 77957729712 scopus 로고    scopus 로고
    • The origin of fibroblasts and mechanism of cardiac fibrosis
    • COI: 1:CAS:528:DC%2BC3cXhtFGqsLzF, PID: 20635395
    • Krenning G, Zeisberg EM, Kalluri R (2010) The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol 225:631–637. doi:10.1002/jcp.22322
    • (2010) J Cell Physiol , vol.225 , pp. 631-637
    • Krenning, G.1    Zeisberg, E.M.2    Kalluri, R.3
  • 73
    • 79956334658 scopus 로고    scopus 로고
    • Heart regeneration
    • COI: 1:CAS:528:DC%2BC3MXmtlels7c%3D, PID: 21593865
    • Laflamme MA, Murry CE (2011) Heart regeneration. Nature 473:326–335. doi:10.1038/nature10147
    • (2011) Nature , vol.473 , pp. 326-335
    • Laflamme, M.A.1    Murry, C.E.2
  • 74
    • 84905109590 scopus 로고    scopus 로고
    • Cardiac fibroblast glycogen synthase kinase-3beta regulates ventricular remodeling and dysfunction in ischemic heart
    • COI: 1:CAS:528:DC%2BC2cXhtlKksL7M, PID: 24899689
    • Lal H, Ahmad F, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai EJ, Woodgett J, Gao E, Force T (2014) Cardiac fibroblast glycogen synthase kinase-3beta regulates ventricular remodeling and dysfunction in ischemic heart. Circulation 130:419–430. doi:10.1161/CIRCULATIONAHA.113.008364
    • (2014) Circulation , vol.130 , pp. 419-430
    • Lal, H.1    Ahmad, F.2    Zhou, J.3    Yu, J.E.4    Vagnozzi, R.J.5    Guo, Y.6    Yu, D.7    Tsai, E.J.8    Woodgett, J.9    Gao, E.10    Force, T.11
  • 75
    • 20844431696 scopus 로고    scopus 로고
    • Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase
    • COI: 1:CAS:528:DC%2BD2cXnvFamsrg%3D, PID: 15466656
    • Landmesser U, Engberding N, Bahlmann FH, Schaefer A, Wiencke A, Heineke A, Spiekermann S, Hilfiker-Kleiner D, Templin C, Kotlarz D, Mueller M, Fuchs M, Hornig B, Haller H, Drexler H (2004) Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation 110:1933–1939. doi:10.1161/01.CIR.0000143232.67642.7A
    • (2004) Circulation , vol.110 , pp. 1933-1939
    • Landmesser, U.1    Engberding, N.2    Bahlmann, F.H.3    Schaefer, A.4    Wiencke, A.5    Heineke, A.6    Spiekermann, S.7    Hilfiker-Kleiner, D.8    Templin, C.9    Kotlarz, D.10    Mueller, M.11    Fuchs, M.12    Hornig, B.13    Haller, H.14    Drexler, H.15
  • 76
    • 74249117848 scopus 로고    scopus 로고
    • Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis
    • COI: 1:CAS:528:DC%2BC3cXjt12itQ%3D%3D, PID: 19730442
    • Laplante P, Sirois I, Raymond MA, Kokta V, Beliveau A, Prat A, Pshezhetsky AV, Hebert MJ (2010) Caspase-3-mediated secretion of connective tissue growth factor by apoptotic endothelial cells promotes fibrosis. Cell Death Differ 17:291–303. doi:10.1038/cdd.2009.124
    • (2010) Cell Death Differ , vol.17 , pp. 291-303
    • Laplante, P.1    Sirois, I.2    Raymond, M.A.3    Kokta, V.4    Beliveau, A.5    Prat, A.6    Pshezhetsky, A.V.7    Hebert, M.J.8
  • 77
    • 84928248724 scopus 로고    scopus 로고
    • Mst1 inhibition rescues beta1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis
    • PID: 25600225
    • Lee GJ, Yan L, Vatner DE, Vatner SF (2015) Mst1 inhibition rescues beta1-adrenergic cardiomyopathy by reducing myocyte necrosis and non-myocyte apoptosis rather than myocyte apoptosis. Basic Res Cardiol 110:7
    • (2015) Basic Res Cardiol , vol.110 , pp. 7
    • Lee, G.J.1    Yan, L.2    Vatner, D.E.3    Vatner, S.F.4
  • 78
    • 0035997535 scopus 로고    scopus 로고
    • Do neutrophils contribute to myocardial reperfusion injury?
    • PID: 12212545
    • Lefer DJ (2002) Do neutrophils contribute to myocardial reperfusion injury? Basic Res Cardiol 97:263–267
    • (2002) Basic Res Cardiol , vol.97 , pp. 263-267
    • Lefer, D.J.1
  • 80
    • 0037376744 scopus 로고    scopus 로고
    • Apoptosis and Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3sXit12ntr0%3D, PID: 12657363
    • Lev N, Melamed E, Offen D (2003) Apoptosis and Parkinson’s disease. Prog Neuropsychopharmacol Biol Psychiatry 27:245–250. doi:10.1016/S0278-5846(03)00019-8
    • (2003) Prog Neuropsychopharmacol Biol Psychiatry , vol.27 , pp. 245-250
    • Lev, N.1    Melamed, E.2    Offen, D.3
  • 81
    • 68149170478 scopus 로고    scopus 로고
    • Cutting edge: necrosis activates the NLRP3 inflammasome
    • COI: 1:CAS:528:DC%2BD1MXoslCktbk%3D, PID: 19596994
    • Li H, Ambade A, Re F (2009) Cutting edge: necrosis activates the NLRP3 inflammasome. J Immunol 183:1528–1532. doi:10.4049/jimmunol.0901080
    • (2009) J Immunol , vol.183 , pp. 1528-1532
    • Li, H.1    Ambade, A.2    Re, F.3
  • 82
    • 70449713477 scopus 로고    scopus 로고
    • Calpain activation contributes to hyperglycaemia-induced apoptosis in cardiomyocytes
    • COI: 1:CAS:528:DC%2BD1MXhtFarsbvK, PID: 19505932
    • Li Y, Feng Q, Arnold M, Peng T (2009) Calpain activation contributes to hyperglycaemia-induced apoptosis in cardiomyocytes. Cardiovasc Res 84:100–110. doi:10.1093/cvr/cvp189
    • (2009) Cardiovasc Res , vol.84 , pp. 100-110
    • Li, Y.1    Feng, Q.2    Arnold, M.3    Peng, T.4
  • 84
    • 0024787759 scopus 로고
    • Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury
    • COI: 1:STN:280:DyaK3c%2FptV2ntA%3D%3D, PID: 2598440
    • Litt MR, Jeremy RW, Weisman HF, Winkelstein JA, Becker LC (1989) Neutrophil depletion limited to reperfusion reduces myocardial infarct size after 90 minutes of ischemia. Evidence for neutrophil-mediated reperfusion injury. Circulation 80:1816–1827
    • (1989) Circulation , vol.80 , pp. 1816-1827
    • Litt, M.R.1    Jeremy, R.W.2    Weisman, H.F.3    Winkelstein, J.A.4    Becker, L.C.5
  • 85
    • 0029610434 scopus 로고
    • Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs
    • COI: 1:STN:280:DyaK287gvFWitg%3D%3D, PID: 8558838
    • Liu Y, Cigola E, Cheng W, Kajstura J, Olivetti G, Hintze TH, Anversa P (1995) Myocyte nuclear mitotic division and programmed myocyte cell death characterize the cardiac myopathy induced by rapid ventricular pacing in dogs. Lab Invest 73:771–787
    • (1995) Lab Invest , vol.73 , pp. 771-787
    • Liu, Y.1    Cigola, E.2    Cheng, W.3    Kajstura, J.4    Olivetti, G.5    Hintze, T.H.6    Anversa, P.7
  • 86
    • 4544381265 scopus 로고    scopus 로고
    • Bcl-2 is a key factor for cardiac fibroblast resistance to programmed cell death
    • COI: 1:CAS:528:DC%2BD2cXmvFemsb0%3D, PID: 15184368
    • Mayorga M, Bahi N, Ballester M, Comella JX, Sanchis D (2004) Bcl-2 is a key factor for cardiac fibroblast resistance to programmed cell death. J Biol Chem 279:34882–34889. doi:10.1074/jbc.M404616200
    • (2004) J Biol Chem , vol.279 , pp. 34882-34889
    • Mayorga, M.1    Bahi, N.2    Ballester, M.3    Comella, J.X.4    Sanchis, D.5
  • 87
    • 0025320928 scopus 로고
    • Energetic response of coronary endothelial cells to hypoxia
    • COI: 1:CAS:528:DyaK3cXitFCnsrk%3D, PID: 2316683
    • Mertens S, Noll T, Spahr R, Krutzfeldt A, Piper HM (1990) Energetic response of coronary endothelial cells to hypoxia. Am J Physiol 258:H689–H694
    • (1990) Am J Physiol , vol.258 , pp. H689-H694
    • Mertens, S.1    Noll, T.2    Spahr, R.3    Krutzfeldt, A.4    Piper, H.M.5
  • 88
    • 79959261693 scopus 로고    scopus 로고
    • Regulation of cell survival mechanisms in Alzheimer’s disease by glycogen synthase kinase-3
    • PID: 21629713
    • Mines MA, Beurel E, Jope RS (2011) Regulation of cell survival mechanisms in Alzheimer’s disease by glycogen synthase kinase-3. Int J Alzheimers Dis 2011:861072. doi:10.4061/2011/861072
    • (2011) Int J Alzheimers Dis , vol.2011 , pp. 861072
    • Mines, M.A.1    Beurel, E.2    Jope, R.S.3
  • 89
    • 0029778441 scopus 로고    scopus 로고
    • Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction
    • COI: 1:STN:280:DyaK28vjvVCntQ%3D%3D, PID: 8840837
    • Misao J, Hayakawa Y, Ohno M, Kato S, Fujiwara T, Fujiwara H (1996) Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction. Circulation 94:1506–1512
    • (1996) Circulation , vol.94 , pp. 1506-1512
    • Misao, J.1    Hayakawa, Y.2    Ohno, M.3    Kato, S.4    Fujiwara, T.5    Fujiwara, H.6
  • 90
    • 0037637429 scopus 로고    scopus 로고
    • A matter of life and death: cardiac myocyte apoptosis and regeneration
    • COI: 1:CAS:528:DC%2BD3sXktVGis7Y%3D, PID: 12750394
    • Nadal-Ginard B, Kajstura J, Anversa P, Leri A (2003) A matter of life and death: cardiac myocyte apoptosis and regeneration. J Clin Investig 111:1457–1459. doi:10.1172/JCI18611
    • (2003) J Clin Investig , vol.111 , pp. 1457-1459
    • Nadal-Ginard, B.1    Kajstura, J.2    Anversa, P.3    Leri, A.4
  • 91
  • 93
    • 0024653907 scopus 로고
    • Ultrastructural mechanisms of myocardial atrophy in white rats during starvation
    • COI: 1:STN:280:DyaL1M3kslyksw%3D%3D, PID: 2720167
    • Nepomniashchikh LM, Semenova LA, Semenov DE (1989) Ultrastructural mechanisms of myocardial atrophy in white rats during starvation. Biull Eksp Biol Med 107:477–481
    • (1989) Biull Eksp Biol Med , vol.107 , pp. 477-481
    • Nepomniashchikh, L.M.1    Semenova, L.A.2    Semenov, D.E.3
  • 94
    • 84903411670 scopus 로고    scopus 로고
    • HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation
    • PID: 25024745
    • Nural-Guvener HF, Zakharova L, Nimlos J, Popovic S, Mastroeni D, Gaballa MA (2014) HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation. Fibrogenesis Tissue Repair 7:10. doi:10.1186/1755-1536-7-10
    • (2014) Fibrogenesis Tissue Repair , vol.7 , pp. 10
    • Nural-Guvener, H.F.1    Zakharova, L.2    Nimlos, J.3    Popovic, S.4    Mastroeni, D.5    Gaballa, M.A.6
  • 95
    • 84874245757 scopus 로고    scopus 로고
    • Attenuation of increased secretory leukocyte protease inhibitor, matricellular proteins and angiotensin II and left ventricular remodeling by candesartan and omapatrilat during healing after reperfused myocardial infarction
    • COI: 1:CAS:528:DC%2BC3sXislarsrk%3D, PID: 23361363
    • Palaniyappan A, Uwiera RR, Idikio H, Menon V, Jugdutt C, Jugdutt BI (2013) Attenuation of increased secretory leukocyte protease inhibitor, matricellular proteins and angiotensin II and left ventricular remodeling by candesartan and omapatrilat during healing after reperfused myocardial infarction. Mol Cell Biochem 376:175–188. doi:10.1007/s11010-013-1565-2
    • (2013) Mol Cell Biochem , vol.376 , pp. 175-188
    • Palaniyappan, A.1    Uwiera, R.R.2    Idikio, H.3    Menon, V.4    Jugdutt, C.5    Jugdutt, B.I.6
  • 96
    • 80155177903 scopus 로고    scopus 로고
    • The apoptotic program promotes tissue remodeling and fibrosis
    • PID: 22042034, (author reply 1108)
    • Pallet N, Hebert MJ (2011) The apoptotic program promotes tissue remodeling and fibrosis. Kidney Int 80:1108. doi:10.1038/ki.2011.307(author reply 1108)
    • (2011) Kidney Int , vol.80 , pp. 1108
    • Pallet, N.1    Hebert, M.J.2
  • 98
    • 84871532581 scopus 로고    scopus 로고
    • Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload
    • PID: 23277091
    • Park M, Vatner SF, Yan L, Gao S, Yoon S, Lee GJ, Xie LH, Kitsis RN, Vatner DE (2013) Novel mechanisms for caspase inhibition protecting cardiac function with chronic pressure overload. Basic Res Cardiol 108:324. doi:10.1007/s00395-012-0324-y
    • (2013) Basic Res Cardiol , vol.108 , pp. 324
    • Park, M.1    Vatner, S.F.2    Yan, L.3    Gao, S.4    Yoon, S.5    Lee, G.J.6    Xie, L.H.7    Kitsis, R.N.8    Vatner, D.E.9
  • 99
    • 67249152096 scopus 로고    scopus 로고
    • Cardiac fibroblasts: at the heart of myocardial remodeling
    • COI: 1:CAS:528:DC%2BD1MXnsFyhtbY%3D, PID: 19460403
    • Porter KE, Turner NA (2009) Cardiac fibroblasts: at the heart of myocardial remodeling. Pharmacol Ther 123:255–278. doi:10.1016/j.pharmthera.2009.05.002
    • (2009) Pharmacol Ther , vol.123 , pp. 255-278
    • Porter, K.E.1    Turner, N.A.2
  • 100
    • 84907612321 scopus 로고    scopus 로고
    • Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade
    • COI: 1:CAS:528:DC%2BC2cXhvFWqs7zN, PID: 25100076
    • Rafatian N, Westcott KV, White RA, Leenen FH (2014) Cardiac macrophages and apoptosis after myocardial infarction: effects of central MR blockade. Am J Physiol Regul Integr Comp Physiol 307:R879–R887. doi:10.1152/ajpregu.00075.2014
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.307 , pp. R879-R887
    • Rafatian, N.1    Westcott, K.V.2    White, R.A.3    Leenen, F.H.4
  • 102
    • 0020583038 scopus 로고
    • Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog
    • COI: 1:STN:280:DyaL3s7ls1Squw%3D%3D, PID: 6831665
    • Romson JL, Hook BG, Kunkel SL, Abrams GD, Schork MA, Lucchesi BR (1983) Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog. Circulation 67:1016–1023
    • (1983) Circulation , vol.67 , pp. 1016-1023
    • Romson, J.L.1    Hook, B.G.2    Kunkel, S.L.3    Abrams, G.D.4    Schork, M.A.5    Lucchesi, B.R.6
  • 103
    • 0032746471 scopus 로고    scopus 로고
    • Viruses and apoptosis
    • COI: 1:CAS:528:DyaK1MXmvVOnsbY%3D, PID: 10547702
    • Roulston A, Marcellus RC, Branton PE (1999) Viruses and apoptosis. Annu Rev Microbiol 53:577–628. doi:10.1146/annurev.micro.53.1.577
    • (1999) Annu Rev Microbiol , vol.53 , pp. 577-628
    • Roulston, A.1    Marcellus, R.C.2    Branton, P.E.3
  • 104
    • 0033022591 scopus 로고    scopus 로고
    • Control of apoptosis of cardiovascular fibroblasts: a novel drug target
    • COI: 1:STN:280:DyaK1MzktFWmtQ%3D%3D, PID: 10412646
    • Rupp H, Maisch B (1999) Control of apoptosis of cardiovascular fibroblasts: a novel drug target. Herz 24:225–231
    • (1999) Herz , vol.24 , pp. 225-231
    • Rupp, H.1    Maisch, B.2
  • 105
    • 0032851595 scopus 로고    scopus 로고
    • Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
    • COI: 1:CAS:528:DyaK1MXms1Wkt7w%3D, PID: 10502825
    • Sawa A, Wiegand GW, Cooper J, Margolis RL, Sharp AH, Lawler JF Jr, Greenamyre JT, Snyder SH, Ross CA (1999) Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nat Med 5:1194–1198. doi:10.1038/13518
    • (1999) Nat Med , vol.5 , pp. 1194-1198
    • Sawa, A.1    Wiegand, G.W.2    Cooper, J.3    Margolis, R.L.4    Sharp, A.H.5    Lawler, J.F.6    Greenamyre, J.T.7    Snyder, S.H.8    Ross, C.A.9
  • 108
    • 0036251035 scopus 로고    scopus 로고
    • Different preservation of myocardial capillary endothelial cells and cardiomyocytes during and after cardioplegic ischemia (25 °C) of canine hearts
    • COI: 1:STN:280:DC%2BD38zgslaqsA%3D%3D, PID: 12049337
    • Schmiedl A, Richter J, Schnabel PA (2002) Different preservation of myocardial capillary endothelial cells and cardiomyocytes during and after cardioplegic ischemia (25 °C) of canine hearts. Pathol Res Pract 198:281–290
    • (2002) Pathol Res Pract , vol.198 , pp. 281-290
    • Schmiedl, A.1    Richter, J.2    Schnabel, P.A.3
  • 109
    • 0030048713 scopus 로고    scopus 로고
    • Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure
    • COI: 1:STN:280:DyaK287jtlSrug%3D%3D, PID: 8546201
    • Sharov VG, Sabbah HN, Shimoyama H, Goussev AV, Lesch M, Goldstein S (1996) Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure. Am J Pathol 148:141–149
    • (1996) Am J Pathol , vol.148 , pp. 141-149
    • Sharov, V.G.1    Sabbah, H.N.2    Shimoyama, H.3    Goussev, A.V.4    Lesch, M.5    Goldstein, S.6
  • 110
    • 78951474945 scopus 로고    scopus 로고
    • Role of endothelial cells in myocardial ischemia-reperfusion injury
    • COI: 1:CAS:528:DC%2BC3cXhsFOmsLnL, PID: 25558187
    • Singhal AK, Symons JD, Boudina S, Jaishy B, Shiu YT (2010) Role of endothelial cells in myocardial ischemia-reperfusion injury. Vasc Dis Prev 7:1–14
    • (2010) Vasc Dis Prev , vol.7 , pp. 1-14
    • Singhal, A.K.1    Symons, J.D.2    Boudina, S.3    Jaishy, B.4    Shiu, Y.T.5
  • 111
    • 0034975840 scopus 로고    scopus 로고
    • Time course of the apoptotic cascade and effects of caspase inhibitors in adult rat ventricular cardiomyocytes
    • COI: 1:CAS:528:DC%2BD3MXjtlSlu7w%3D, PID: 11343420
    • Suzuki K, Kostin S, Person V, Elsasser A, Schaper J (2001) Time course of the apoptotic cascade and effects of caspase inhibitors in adult rat ventricular cardiomyocytes. J Mol Cell Cardiol 33:983–994. doi:10.1006/jmcc.2001.1364
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 983-994
    • Suzuki, K.1    Kostin, S.2    Person, V.3    Elsasser, A.4    Schaper, J.5
  • 113
    • 0032526370 scopus 로고    scopus 로고
    • Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction
    • COI: 1:CAS:528:DyaK1cXjvVCms74%3D, PID: 9633913
    • Takemura G, Ohno M, Hayakawa Y, Misao J, Kanoh M, Ohno A, Uno Y, Minatoguchi S, Fujiwara T, Fujiwara H (1998) Role of apoptosis in the disappearance of infiltrated and proliferated interstitial cells after myocardial infarction. Circ Res 82:1130–1138
    • (1998) Circ Res , vol.82 , pp. 1130-1138
    • Takemura, G.1    Ohno, M.2    Hayakawa, Y.3    Misao, J.4    Kanoh, M.5    Ohno, A.6    Uno, Y.7    Minatoguchi, S.8    Fujiwara, T.9    Fujiwara, H.10
  • 114
    • 0027935409 scopus 로고
    • Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes
    • COI: 1:CAS:528:DyaK2cXlsFClsLg%3D, PID: 7520371
    • Tanaka M, Ito H, Adachi S, Akimoto H, Nishikawa T, Kasajima T, Marumo F, Hiroe M (1994) Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 75:426–433
    • (1994) Circ Res , vol.75 , pp. 426-433
    • Tanaka, M.1    Ito, H.2    Adachi, S.3    Akimoto, H.4    Nishikawa, T.5    Kasajima, T.6    Marumo, F.7    Hiroe, M.8
  • 115
    • 84874092627 scopus 로고    scopus 로고
    • Contrasting inflammation resolution during atherosclerosis and post myocardial infarction at the level of monocyte/macrophage phagocytic clearance
    • PID: 22566922
    • Thorp EB (2012) Contrasting inflammation resolution during atherosclerosis and post myocardial infarction at the level of monocyte/macrophage phagocytic clearance. Front Immunol 3:39. doi:10.3389/fimmu.2012.00039
    • (2012) Front Immunol , vol.3 , pp. 39
    • Thorp, E.B.1
  • 116
    • 77956354653 scopus 로고    scopus 로고
    • Cell communications in the heart
    • PID: 20805439
    • Tirziu D, Giordano FJ, Simons M (2010) Cell communications in the heart. Circulation 122:928–937. doi:10.1161/CIRCULATIONAHA.108.847731
    • (2010) Circulation , vol.122 , pp. 928-937
    • Tirziu, D.1    Giordano, F.J.2    Simons, M.3
  • 118
    • 84874958737 scopus 로고    scopus 로고
    • Function and fate of myofibroblasts after myocardial infarction
    • COI: 1:CAS:528:DC%2BC3sXltVKjtrk%3D, PID: 23448358
    • Turner NA, Porter KE (2013) Function and fate of myofibroblasts after myocardial infarction. Fibrogenesis Tissue Repair 6:5. doi:10.1186/1755-1536-6-5
    • (2013) Fibrogenesis Tissue Repair , vol.6 , pp. 5
    • Turner, N.A.1    Porter, K.E.2
  • 119
    • 34247849521 scopus 로고    scopus 로고
    • Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice
    • PID: 17322368
    • van Amerongen MJ, Harmsen MC, van Rooijen N, Petersen AH, van Luyn MJ (2007) Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol 170:818–829. doi:10.2353/ajpath.2007.060547
    • (2007) Am J Pathol , vol.170 , pp. 818-829
    • van Amerongen, M.J.1    Harmsen, M.C.2    van Rooijen, N.3    Petersen, A.H.4    van Luyn, M.J.5
  • 120
    • 1142309740 scopus 로고    scopus 로고
    • Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury
    • COI: 1:CAS:528:DC%2BD2cXhtFWmsLo%3D, PID: 14962479
    • Vinten-Johansen J (2004) Involvement of neutrophils in the pathogenesis of lethal myocardial reperfusion injury. Cardiovasc Res 61:481–497. doi:10.1016/j.cardiores.2003.10.011
    • (2004) Cardiovasc Res , vol.61 , pp. 481-497
    • Vinten-Johansen, J.1
  • 121
    • 84962680223 scopus 로고
    • Die Cellularpathologie in ihrer Begrundung auf physiologische und pathologische Gewebelehre
    • Virchow R (1859) Die Cellularpathologie in ihrer Begrundung auf physiologische und pathologische Gewebelehre, Berlin
    • (1859) Berlin
    • Virchow, R.1
  • 124
    • 0028173386 scopus 로고
    • The alpha-smooth muscle actin-positive cells in healing human myocardial scars
    • COI: 1:STN:280:DyaK2M%2FivFOitQ%3D%3D, PID: 7943177
    • Willems IE, Havenith MG, De Mey JG, Daemen MJ (1994) The alpha-smooth muscle actin-positive cells in healing human myocardial scars. Am J Pathol 145:868–875
    • (1994) Am J Pathol , vol.145 , pp. 868-875
    • Willems, I.E.1    Havenith, M.G.2    De Mey, J.G.3    Daemen, M.J.4
  • 125
    • 84872646115 scopus 로고
    • Myocardial and endocardial fibrosis with cardiac failure
    • COI: 1:STN:280:DyaH28%2FhvFKksg%3D%3D
    • Wright J, Collins WT et al (1946) Myocardial and endocardial fibrosis with cardiac failure. Cin J Med 27:813–823
    • (1946) Cin J Med , vol.27 , pp. 813-823
    • Wright, J.1    Collins, W.T.2
  • 126
    • 84893490518 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy
    • PID: 24334905
    • Xu X, Bucala R, Ren J (2013) Macrophage migration inhibitory factor deficiency augments doxorubicin-induced cardiomyopathy. J Am Heart Assoc 2:e000439. doi:10.1161/JAHA.113.000439
    • (2013) J Am Heart Assoc , vol.2 , pp. e000439
    • Xu, X.1    Bucala, R.2    Ren, J.3
  • 128
    • 84922392149 scopus 로고    scopus 로고
    • Disruption of type 5 adenylyl cyclase prevents beta-adrenergic receptor cardiomyopathy: a novel approach to beta-adrenergic receptor blockade
    • COI: 1:CAS:528:DC%2BC2cXitVeitLbF, PID: 25193472
    • Yan L, Vatner SF, Vatner DE (2014) Disruption of type 5 adenylyl cyclase prevents beta-adrenergic receptor cardiomyopathy: a novel approach to beta-adrenergic receptor blockade. Am J Physiol Heart circ Physiol 307:H1521–H1528. doi:10.1152/ajpheart.00491.2014
    • (2014) Am J Physiol Heart circ Physiol , vol.307 , pp. H1521-H1528
    • Yan, L.1    Vatner, S.F.2    Vatner, D.E.3
  • 129
  • 130
    • 78650358123 scopus 로고    scopus 로고
    • Origins of cardiac fibroblasts
    • COI: 1:CAS:528:DC%2BC3cXhsVCkurvO, PID: 21106947
    • Zeisberg EM, Kalluri R (2010) Origins of cardiac fibroblasts. Circ Res 107:1304–1312. doi:10.1161/CIRCRESAHA.110.231910
    • (2010) Circ Res , vol.107 , pp. 1304-1312
    • Zeisberg, E.M.1    Kalluri, R.2
  • 131
    • 34548862310 scopus 로고    scopus 로고
    • Increased apoptosis and myocyte enlargement with decreased cardiac mass; distinctive features of the aging male, but not female, monkey heart
    • COI: 1:CAS:528:DC%2BD2sXhtFWitL%2FP, PID: 17720187
    • Zhang XP, Vatner SF, Shen YT, Rossi F, Tian Y, Peppas A, Resuello RR, Natividad FF, Vatner DE (2007) Increased apoptosis and myocyte enlargement with decreased cardiac mass; distinctive features of the aging male, but not female, monkey heart. J Mol Cell Cardiol 43:487–491. doi:10.1016/j.yjmcc.2007.07.048
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 487-491
    • Zhang, X.P.1    Vatner, S.F.2    Shen, Y.T.3    Rossi, F.4    Tian, Y.5    Peppas, A.6    Resuello, R.R.7    Natividad, F.F.8    Vatner, D.E.9
  • 132
    • 84881651936 scopus 로고    scopus 로고
    • Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction
    • COI: 1:CAS:528:DC%2BC3sXhsVehu7jP, PID: 23771691
    • Zhao X, Zhang W, Xing D, Li P, Fu J, Gong K, Hage FG, Oparil S, Chen YF (2013) Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol 305:H590–H598
    • (2013) Am J Physiol Heart Circ Physiol , vol.305 , pp. H590-H598
    • Zhao, X.1    Zhang, W.2    Xing, D.3    Li, P.4    Fu, J.5    Gong, K.6    Hage, F.G.7    Oparil, S.8    Chen, Y.F.9


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