Apoptosis in myocytes in end-stage heart failure

New England Journal of Medicine

Volumn 335, Issue 16, 1996, Pages 1182-1189

  Narula, Jagat ^a,b   Haider, Nezam ^b   Virmani, Renu ^c   Disalvo, Thomas G ^a   Kolodgie, Frank D ^c   Hajjar, Roger J ^a   Schmidt, Ulrich ^a   Semigran, Marc J ^a   Dec, G William ^a   Khaw, Ban An ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

^c ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT;

ADULT; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CELL DEATH; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSIS; ETIOLOGY; EXPLANT; FEMALE; HEART DILATATION; HEART FAILURE; HEART MUSCLE CELL; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL;

ACCIDENTS, TRAFFIC; ADOLESCENT; APOPTOSIS; CARDIOMYOPATHY, DILATED; CHRONIC DISEASE; DNA DAMAGE; DNA NUCLEOTIDYLEXOTRANSFERASE; ELECTROPHORESIS, AGAR GEL; FEMALE; HEART FAILURE, CONGESTIVE; HEART TRANSPLANTATION; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIUM;

EID: 10244254975     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199610173351603     Document Type: Article

References (40)

1. Transit from cardiac hypertrophy to overt heart failure. NIH guide 24. No. 25. Bethesda, Md.: National Institutes of Health, 1995. (Publication no. NHLBI-PA-95-075.)
2. Dec GW. Prognosis in congestive heart failure: what information can best predict the future? J Nucl Med 1992;33:477-9.
3. Braunwald E. Pathophysiology of heart failure. In: Braunwald E, ed. Heart disease: a textbook of cardiovascular medicine. 4th ed. Philadelphia: W.B. Saunders, 1992:393-418.
4. Katz AM. The cardiomyopathy of overload: an unnatural growth response in the hypertrophied heart. Ann Intern Med 1994;121:363-71.
5. Chien KR, Zhu H, Knowlton KU, et al. Transcriptional regulation during cardiac growth and development. Annu Rev Physiol 1993;55:77-95.
6. Izumo S, Nadal-Ginard B, Mahdavi V. Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload. Proc Natl Acad Sci U S A 1988;85:339-43.
7. Bing OHL. Hypothesis: apoptosis may be a mechanism for the transition to heart failure with chronic pressure overload. J Mol Cell Cardiol 1994;26:943-8.
8. Kerr JFR, Wyllie AH, Currie AR. Apotosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972; 26:239-57.
9. Wyllie AH, Kerr JF, Currie AR. Cell death: the significance of apoptosis. Int Rev Cytol 1980;68:251-306.
10. Searle J, Kerr JFR, Bishop CJ. Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance. Pathol Annu 1982; 17:229-59.
11. Ucker DS. Death by suicide: one way to go in mammalian cellular development? New Biol 1991;3:103-9.
12. Arends MI, Wyllie AH. Apoptosis: mechanisms and roles in pathology. Int Rev Exp Pathol 1991,32:223-54.
13. Arends MJ, Morris RG, Wyllie AH. Apoptosis: the role of endonuclease. Am J Pathol 1990;136:593-608.
14. Bursch W, Kleine L, Tenniswood M. The biochemistry of cell death by apoptosis. Biochem Cell Biol 1990;68:1071-4.
15. Nagata S, Golstein P. The Fas death factor. Science 1995;267:1449-56.
16. Nicholson DW, Ali A, Thornberry NA, et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995;376:37-43.
17. Fernandes-Alnemri T, Litwack G, Alnemri ES. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 β;-converting enzyme. J Biol Chem 1994;269:30761-4.
18. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 1991;352:345-7.
19. Evan GI, Wyllie AH, Gilbert CS, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992;69:119-28.
20. Hockenbery DM, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-6.
21. Rosl F. A simple and rapid method for detection of apoptosis in human cells. Nucleic Acids Res 1992;20:5243.
22. Gavrielli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493-501.
23. Wijsman JH, Jonker RR, Keijzer R, van de Velde CJ, Cornelisse CJ, van Dierendonck JH. A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA. J Histochem Cytochem 1993;41:7-12.
24. Itoh G, Tamura J, Suzuki M, et al. DNA fragmentation of human infarcted myocardial cells demonstrated by the nick end labeling method and DNA agarose gel electrophoresis. Am J Pathol 1995;146:1325-31.
25. Sandford NL, Searle JW, Kerr JF. Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation. Pathology 1984;16:406-10.
26. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett G. Macrophage phagocytosis of aging neutrophils in inflammation: programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 1989;83:865-75.
27. Wyllie AH. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980;284:555-6.
28. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest 1994;94:1621-8.
29. Tanaka M, Ito H, Adachi S, et al. Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes. Circ Res 1994;75:426-33.
30. Murgia M, Pizzo P, Sandona D, Zanovello P, Rizzuto R, Di Virgilio F. Mitochondrial DNA is not fragmented during apoptosis. J Biol Chem 1992;267:10939-41.
31. Takahashi T, Schunkert H, Isoyama S, et al. Age-related differences in the expression of proto-oncogenes and contractile protein genes in response to pressure overload in the rat myocardium. J Clin Invest 1992;89:939-46.
32. Sadoshima J, Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: critical role of the ATI receptor subtype. Circ Res 1993;73:413-23.
33. Gwathmey JK, Morgan JP. Altered calcium handling in experimental pressure-overload hypertrophy in the ferret. Circ Res 1985;57:836-43.
34. Martikainen P, Kyprianou N, Tucker RW, Isaacs JT. Programmed death of nonproliferating androgen-independent prostatic cancer cells. Cancer Res 1991;51:4693-700.
35. Connor J, Sawczuk IS, Benson MC, et al. Calcium channel antagonists delay regression of androgen-dependent tissues and suppress gene activity associated with cell death. Prostate 1988;13:119-30.
36. McConkcy DJ, Hartzell P, Chow SC, Orrenius S, Jondal M. Interleukin 1 inhibits T cell receptor-mediated apoptosis in immature thymocytes. J Biol Chem 1990;265:3009-11.
37. McConkey DJ, Hartzell P, Nicotera P, Orrenius S. Calcium-activated DNA fragmentation kills immature thymocytes. FASEB J 1989;3:1843-9.
38. Marcus ML, Mueller TB, Eastham CL. Effects of short- and long-term left ventricular hypertrophy on coronary circulation. Am J Physiol 1981; 241:H358-H362.
39. Her E, Frazer J, Austen KF, Owen WF Jr. Eosinophil hematopoietins antagonize the programmed cell death of eosinophils: cytokine and glucocorticoid effects on eosinophils maintained by endothelial cell-conditioned medium. J Clin Invest 1991;88:1982-7
40. Williams GT, Smith CA, Spooncer E, Dexter TM, Taylor DR. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 1990;343:76-9.