Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart

Circulation

Volumn 130, Issue 5, 2014, Pages 419-430

  Lal, Hind ^a,c   Ahmad, Firdos ^a,c   Zhou, Jibin ^a   Yu, Justine E ^a   Vagnozzi, Ronald J ^a   Guo, Yuanjun ^a,c   Yu, Daohai ^a   Tsai, Emily J ^a   Woodgett, James ^a,b   Gao, Erhe ^a   Force, Thomas ^a,c  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOUNT SINAI HOSPITAL   (Canada)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Fibroblasts; Fibrosis; Glycogen synthase kinase 3 beta; Hypertrophy; Myocardial infarction

Indexed keywords

CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; MYC PROTEIN; PROTEIN KINASE B; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; SMAD3 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL TISSUE; ARTICLE; ENZYME PHOSPHORYLATION; FIBROBLAST; FIBROGENESIS; GENE TARGETING; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBROSIS; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FAILURE; HEART VENTRICLE REMODELING; HUMAN; HUMAN TISSUE; MOUSE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SCAR FORMATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; AGED; ANIMAL; CYTOLOGY; ENZYME ACTIVATION; ENZYMOLOGY; EXTRACELLULAR MATRIX; FIBROSIS; GENETICS; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; KNOCKOUT MOUSE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE;

AGED; ANIMALS; ENZYME ACTIVATION; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBROSIS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; MALE; MICE, KNOCKOUT; MIDDLE AGED; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PRIMARY CELL CULTURE; RNA, SMALL INTERFERING; SMAD3 PROTEIN; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84905109590     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.008364     Document Type: Article

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