-
1
-
-
60449094498
-
Heart disease and stroke statistics-2009 update: A report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
-
Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, Ford E, Furie K, Go A, Greenlund K, Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J, Mozaffarian D, Nichol G, O'Donnell C, Roger V, Rosamond W, Sacco R, Sorlie P, Stafford R, Steinberger J, Thom T, Wasserthiel-Smoller S, Wong N, Wylie-Rosett J, Hong Y. Heart disease and stroke statistics-2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation. 2009;119:480-486.
-
(2009)
Circulation
, vol.119
, pp. 480-486
-
-
Lloyd-Jones, D.1
Adams, R.2
Carnethon, M.3
De Simone, G.4
Ferguson, T.B.5
Flegal, K.6
Ford, E.7
Furie, K.8
Go, A.9
Greenlund, K.10
Haase, N.11
Hailpern, S.12
Ho, M.13
Howard, V.14
Kissela, B.15
Kittner, S.16
Lackland, D.17
Lisabeth, L.18
Marelli, A.19
McDermott, M.20
Meigs, J.21
Mozaffarian, D.22
Nichol, G.23
O'Donnell, C.24
Roger, V.25
Rosamond, W.26
Sacco, R.27
Sorlie, P.28
Stafford, R.29
Steinberger, J.30
Thom, T.31
Wasserthiel-Smoller, S.32
Wong, N.33
Wylie-Rosett, J.34
Hong, Y.35
more..
-
2
-
-
50449111231
-
Regulation of coronary blood flow during exercise
-
Duncker DJ, Bache RJ. Regulation of coronary blood flow during exercise. Physiol Rev. 2008;88:1009-1086.
-
(2008)
Physiol Rev
, vol.88
, pp. 1009-1086
-
-
Duncker, D.J.1
Bache, R.J.2
-
3
-
-
0026525559
-
Angiogenesis in skeletal and cardiac muscle
-
Hudlicka O, Brown M, Egginton S. Angiogenesis in skeletal and cardiac muscle. Physiol Rev. 1992;72:369-417.
-
(1992)
Physiol Rev
, vol.72
, pp. 369-417
-
-
Hudlicka, O.1
Brown, M.2
Egginton, S.3
-
4
-
-
0344825953
-
Athlete's heart
-
Fagard R. Athlete's heart. Heart. 2003;89:1455-1461.
-
(2003)
Heart
, vol.89
, pp. 1455-1461
-
-
Fagard, R.1
-
5
-
-
0035051054
-
Cytoplasmic signaling pathways that regulate cardiac hypertrophy
-
Molkentin JD, Dorn GW II. Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu Rev Physiol. 2001;63:391-426.
-
(2001)
Annu Rev Physiol
, vol.63
, pp. 391-426
-
-
Molkentin, J.D.1
Dorn, G.W.I.I.2
-
6
-
-
34247877577
-
The fuzzy logic of physiological cardiac hypertrophy
-
Dorn GW II. The fuzzy logic of physiological cardiac hypertrophy. Hypertension. 2007;49:962-970.
-
(2007)
Hypertension
, vol.49
, pp. 962-970
-
-
Dorn, G.W.I.I.1
-
7
-
-
33847124544
-
Decompensation of cardiac hypertrophy: Cellular mechanisms and novel therapeutic targets
-
Diwan A, Dorn GW II. Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets. Physiology (Bethesda). 2007; 22:56-64.
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 56-64
-
-
Diwan, A.1
Dorn, G.W.I.I.2
-
8
-
-
67650071028
-
Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages
-
Bu L, Jiang X, Martin-Puig S, Caron L, Zhu S, Shao Y, Roberts DJ, Huang PL, Domian IJ, Chien KR. Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Nature. 2009; 460:113-117.
-
(2009)
Nature
, vol.460
, pp. 113-117
-
-
Bu, L.1
Jiang, X.2
Martin-Puig, S.3
Caron, L.4
Zhu, S.5
Shao, Y.6
Roberts, D.J.7
Huang, P.L.8
Domian, I.J.9
Chien, K.R.10
-
9
-
-
0038380271
-
Phenotyping hypertrophy: Eschew obfuscation
-
Dorn GW II, Robbins J, Sugden PH. Phenotyping hypertrophy: eschew obfuscation. Circ Res. 2003;92:1171-1175.
-
(2003)
Circ Res
, vol.92
, pp. 1171-1175
-
-
Dorn, G.W.I.I.1
Robbins, J.2
Sugden, P.H.3
-
10
-
-
33748323383
-
Regulation of cardiac hypertrophy by intra-cellular signalling pathways
-
Heineke J, Molkentin JD. Regulation of cardiac hypertrophy by intra-cellular signalling pathways. Nat Rev Mol Cell Biol. 2006;7:589-600.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
11
-
-
1242341961
-
Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy
-
Shohet RV, Kisanuki YY, Zhao XS, Siddiquee Z, Franco F, Yanagisawa M. Mice with cardiomyocyte-specific disruption of the endothelin-1 gene are resistant to hyperthyroid cardiac hypertrophy. Proc Natl Acad Sci\USA. 2004;101:2088-2093.
-
(2004)
Proc Natl Acad Sci\USA
, vol.101
, pp. 2088-2093
-
-
Shohet, R.V.1
Kisanuki, Y.Y.2
Zhao, X.S.3
Siddiquee, Z.4
Franco, F.5
Yanagisawa, M.6
-
12
-
-
0242664032
-
Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol
-
Kedzierski RM, Grayburn PA, Kisanuki YY, Williams CS, Hammer RE, Richardson JA, Schneider MD, Yanagisawa M. Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol. Mol Cell Biol. 2003;23:8226-8232.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 8226-8232
-
-
Kedzierski, R.M.1
Grayburn, P.A.2
Kisanuki, Y.Y.3
Williams, C.S.4
Hammer, R.E.5
Richardson, J.A.6
Schneider, M.D.7
Yanagisawa, M.8
-
13
-
-
0032037579
-
Gap junction function: The messenger and the message
-
Steinberg TH. Gap junction function: the messenger and the message. Am J Pathol. 1998;152:851-854.
-
(1998)
Am J Pathol
, vol.152
, pp. 851-854
-
-
Steinberg, T.H.1
-
14
-
-
0034283053
-
Role of gap junctions in cardiac conduction and development: Insights from the connexin knockout mice
-
Lo CW. Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice. Circ Res. 2000;87:346-348.
-
(2000)
Circ Res
, vol.87
, pp. 346-348
-
-
Lo, C.W.1
-
15
-
-
0028907907
-
Cardiac malformation in neonatal mice lacking connexin43
-
Reaume AG, de Sousa PA, Kulkarni S, Langille BL, Zhu D, Davies TC, Juneja SC, Kidder GM, Rossant J. Cardiac malformation in neonatal mice lacking connexin43. Science. 1995;267:1831-1834.
-
(1995)
Science
, vol.267
, pp. 1831-1834
-
-
Reaume, A.G.1
De Sousa, P.A.2
Kulkarni, S.3
Langille, B.L.4
Zhu, D.5
Davies, T.C.6
Juneja, S.C.7
Kidder, G.M.8
Rossant, J.9
-
16
-
-
0043026950
-
High incidence of cardiac malformations in connexin40-deficient mice
-
Gu H, Smith FC, Taffet SM, Delmar M. High incidence of cardiac malformations in connexin40-deficient mice. Circ Res. 2003;93: 201-206.
-
(2003)
Circ Res
, vol.93
, pp. 201-206
-
-
Gu, H.1
Smith, F.C.2
Taffet, S.M.3
Delmar, M.4
-
17
-
-
33751202968
-
Cardiomyocyte-restricted deletion of connexin43 during mouse development
-
Eckardt D, Kirchhoff S, Kim JS, Degen J, Theis M, Ott T, Wiesmann F, Doevendans PA, Lamers WH, de Bakker JM, van Rijen HV, Schneider MD, Willecke K. Cardiomyocyte-restricted deletion of connexin43 during mouse development. J Mol Cell Cardiol. 2006;41:963-971.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 963-971
-
-
Eckardt, D.1
Kirchhoff, S.2
Kim, J.S.3
Degen, J.4
Theis, M.5
Ott, T.6
Wiesmann, F.7
Doevendans, P.A.8
Lamers, W.H.9
De Bakker, J.M.10
Van Rijen, H.V.11
Schneider, M.D.12
Willecke, K.13
-
18
-
-
51749110724
-
Remodelling of gap junctions and connexin expression in diseased myocardium
-
Severs NJ, Bruce AF, Dupont E, Rothery S. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc Res. 2008;80:9-19.
-
(2008)
Cardiovasc Res
, vol.80
, pp. 9-19
-
-
Severs, N.J.1
Bruce, A.F.2
Dupont, E.3
Rothery, S.4
-
19
-
-
66149087287
-
Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction
-
Kieken F, Mutsaers N, Dolmatova E, Virgil K, Wit AL, Kellezi A, Hirst-Jensen BJ, Duffy HS, Sorgen PL. Structural and molecular mechanisms of gap junction remodeling in epicardial border zone myocytes following myocardial infarction. Circ Res. 2009;104:1103-1112.
-
(2009)
Circ Res
, vol.104
, pp. 1103-1112
-
-
Kieken, F.1
Mutsaers, N.2
Dolmatova, E.3
Virgil, K.4
Wit, A.L.5
Kellezi, A.6
Hirst-Jensen, B.J.7
Duffy, H.S.8
Sorgen, P.L.9
-
20
-
-
0032517847
-
Gap junction-mediated cell-cell communication modulates mouse neural crest migration
-
Huang GY, Cooper ES, Waldo K, Kirby ML, Gilula NB, Lo CW. Gap junction-mediated cell-cell communication modulates mouse neural crest migration. J Cell Biol. 1998;143:1725-1734.
-
(1998)
J Cell Biol
, vol.143
, pp. 1725-1734
-
-
Huang, G.Y.1
Cooper, E.S.2
Waldo, K.3
Kirby, M.L.4
Gilula, N.B.5
Lo, C.W.6
-
21
-
-
33745094980
-
Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube
-
Liu S, Liu F, Schneider AE, St Amand T, Epstein JA, Gutstein DE. Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube. Development. 2006;133: 2063-2073.
-
(2006)
Development
, vol.133
, pp. 2063-2073
-
-
Liu, S.1
Liu, F.2
Schneider, A.E.3
St Amand, T.4
Epstein, J.A.5
Gutstein, D.E.6
-
22
-
-
0036333778
-
An essential role for connexin43 gap junctions in mouse coronary artery development
-
Li WE, Waldo K, Linask KL, Chen T, Wessels A, Parmacek MS, Kirby ML, Lo CW. An essential role for connexin43 gap junctions in mouse coronary artery development. Development. 2002;129:2031-2042.
-
(2002)
Development
, vol.129
, pp. 2031-2042
-
-
Li, W.E.1
Waldo, K.2
Linask, K.L.3
Chen, T.4
Wessels, A.5
Parmacek, M.S.6
Kirby, M.L.7
Lo, C.W.8
-
23
-
-
0026475576
-
Differences in gap junction channels between cardiac myocytes, fibroblasts, and heterologous pairs
-
Rook MB, van Ginneken AC, de Jonge B, el Aoumari A, Gros D, Jongsma HJ. Differences in gap junction channels between cardiac myocytes, fibroblasts, and heterologous pairs. Am J Physiol. 1992;263: C959-C977.
-
(1992)
Am J Physiol
, vol.263
-
-
Rook, M.B.1
Van Ginneken, A.C.2
De Jonge, B.3
El Aoumari, A.4
Gros, D.5
Jongsma, H.J.6
-
24
-
-
68049093192
-
Cardiac alternans induced by fibroblast-myocyte coupling: Mechanistic insights from computational models
-
Xie Y, Garfinkel A, Weiss JN, Qu Z. Cardiac alternans induced by fibroblast-myocyte coupling: mechanistic insights from computational models. Am J Physiol Heart Circ Physiol. 2009;297:H775-H784.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Xie, Y.1
Garfinkel, A.2
Weiss, J.N.3
Qu, Z.4
-
25
-
-
58849138363
-
Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats
-
Ming J, Li T, Zhang Y, Xu J, Yang G, Liu L. Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats. Shock. 2009;31:80-86.
-
(2009)
Shock
, vol.31
, pp. 80-86
-
-
Ming, J.1
Li, T.2
Zhang, Y.3
Xu, J.4
Yang, G.5
Liu, L.6
-
26
-
-
0028231045
-
Bidirectional electrical communication between smooth muscle and endothelial cells in the pig coronary artery
-
Beny JL, Pacicca C. Bidirectional electrical communication between smooth muscle and endothelial cells in the pig coronary artery. Am J Physiol. 1994;266:H1465-H1472.
-
(1994)
Am J Physiol
, vol.266
-
-
Beny, J.L.1
Pacicca, C.2
-
27
-
-
0036164668
-
Altered pattern of vascular connexin expression in atherosclerotic plaques
-
Kwak BR, Mulhaupt F, Veillard N, Gros DB, Mach F. Altered pattern of vascular connexin expression in atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 2002;22:225-230.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 225-230
-
-
Kwak, B.R.1
Mulhaupt, F.2
Veillard, N.3
Gros, D.B.4
MacH, F.5
-
29
-
-
0032550290
-
Regulation of vascular connexin43 gene expression by mechanical loads
-
Cowan DB, Lye SJ, Langille BL. Regulation of vascular connexin43 gene expression by mechanical loads. Circ Res. 1998;82:786-793.
-
(1998)
Circ Res
, vol.82
, pp. 786-793
-
-
Cowan, D.B.1
Lye, S.J.2
Langille, B.L.3
-
30
-
-
35648949369
-
Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy
-
Zemljic-Harpf AE, Miller JC, Henderson SA, Wright AT, Manso AM, Elsherif L, Dalton ND, Thor AK, Perkins GA, McCulloch AD, Ross RS. Cardiac-myocyte- specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy. Mol Cell Biol. 2007;27:7522-7537.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7522-7537
-
-
Zemljic-Harpf, A.E.1
Miller, J.C.2
Henderson, S.A.3
Wright, A.T.4
Manso, A.M.5
Elsherif, L.6
Dalton, N.D.7
Thor, A.K.8
Perkins, G.A.9
McCulloch, A.D.10
Ross, R.S.11
-
31
-
-
0031930918
-
Fibroblast growth factor 2 control of vascular tone
-
Zhou M, Sutliff RL, Paul RJ, Lorenz JN, Hoying JB, Haudenschild CC, Yin M, Coffin JD, Kong L, Kranias EG, Luo W, Boivin GP, Duffy JJ, Pawlowski SA, Doetschman T. Fibroblast growth factor 2 control of vascular tone. Nat Med. 1998;4:201-207.
-
(1998)
Nat Med
, vol.4
, pp. 201-207
-
-
Zhou, M.1
Sutliff, R.L.2
Paul, R.J.3
Lorenz, J.N.4
Hoying, J.B.5
Haudenschild, C.C.6
Yin, M.7
Coffin, J.D.8
Kong, L.9
Kranias, E.G.10
Luo, W.11
Boivin, G.P.12
Duffy, J.J.13
Pawlowski, S.A.14
Doetschman, T.15
-
32
-
-
14344279280
-
A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
-
Giordano FJ, Gerber HP, Williams SP, VanBruggen N, Bunting S, Ruiz-Lozano P, Gu Y, Nath AK, Huang Y, Hickey R, Dalton N, Peterson KL, Ross J Jr, Chien KR, Ferrara N. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function. Proc Natl Acad Sci\USA. 2001;98: 5780-5785.
-
(2001)
Proc Natl Acad Sci\USA
, vol.98
, pp. 5780-5785
-
-
Giordano, F.J.1
Gerber, H.P.2
Williams, S.P.3
Vanbruggen, N.4
Bunting, S.5
Ruiz-Lozano, P.6
Gu, Y.7
Nath, A.K.8
Huang, Y.9
Hickey, R.10
Dalton, N.11
Peterson, K.L.12
Ross Jr., J.13
Chien, K.R.14
Ferrara, N.15
-
33
-
-
0344705115
-
VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis
-
Li J, Brown LF, Hibberd MG, Grossman JD, Morgan JP, Simons M. VEGF, flk-1, and flt-1 expression in a rat myocardial infarction model of angiogenesis. Am J Physiol. 1996;270:H1803-H1811.
-
(1996)
Am J Physiol
, vol.270
-
-
Li, J.1
Brown, L.F.2
Hibberd, M.G.3
Grossman, J.D.4
Morgan, J.P.5
Simons, M.6
-
34
-
-
33750724483
-
Enhanced microvascular relaxations to VEGF and bFGF in chronically ischemic porcine myocardium
-
Sellke FW, Wang SY, Stamler A, Lopez JJ, Li J, Li J, Simons M. Enhanced microvascular relaxations to VEGF and bFGF in chronically ischemic porcine myocardium. Am J Physiol. 1996;271:H713-H720.
-
(1996)
Am J Physiol
, vol.271
-
-
Sellke, F.W.1
Wang, S.Y.2
Stamler, A.3
Lopez, J.J.4
Li, J.5
Li, J.6
Simons, M.7
-
35
-
-
0037020157
-
Akt signaling mediates postnatal heart growth in response to insulin and nutritional status
-
Shiojima I, Yefremashvili M, Luo Z, Kureishi Y, Takahashi A, Tao J, Rosenzweig A, Kahn CR, Abel ED, Walsh K. Akt signaling mediates postnatal heart growth in response to insulin and nutritional status. J Biol Chem. 2002;277:37670-37677.
-
(2002)
J Biol Chem
, vol.277
, pp. 37670-37677
-
-
Shiojima, I.1
Yefremashvili, M.2
Luo, Z.3
Kureishi, Y.4
Takahashi, A.5
Tao, J.6
Rosenzweig, A.7
Kahn, C.R.8
Abel, E.D.9
Walsh, K.10
-
36
-
-
0037151104
-
Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart
-
Matsui T, Li L, Wu JC, Cook SA, Nagoshi T, Picard MH, Liao R, Rosenzweig A. Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart. J Biol Chem. 2002;277: 22896-22901.
-
(2002)
J Biol Chem
, vol.277
, pp. 22896-22901
-
-
Matsui, T.1
Li, L.2
Wu, J.C.3
Cook, S.A.4
Nagoshi, T.5
Picard, M.H.6
Liao, R.7
Rosenzweig, A.8
-
37
-
-
23644439061
-
Disruption of coordinated cardiac hypertrophy and angio-genesis contributes to the transition to heart failure
-
Shiojima I, Sato K, Izumiya Y, Schiekofer S, Ito M, Liao R, Colucci WS, Walsh K. Disruption of coordinated cardiac hypertrophy and angio-genesis contributes to the transition to heart failure. J Clin Invest. 2005;115:2108-2118.
-
(2005)
J Clin Invest
, vol.115
, pp. 2108-2118
-
-
Shiojima, I.1
Sato, K.2
Izumiya, Y.3
Schiekofer, S.4
Ito, M.5
Liao, R.6
Colucci, W.S.7
Walsh, K.8
-
38
-
-
36048988646
-
Cardiac growth and angiogenesis coordinated by intertissue interactions
-
Walsh K, Shiojima I. Cardiac growth and angiogenesis coordinated by intertissue interactions. J Clin Invest. 2007;117:3176-3179.
-
(2007)
J Clin Invest
, vol.117
, pp. 3176-3179
-
-
Walsh, K.1
Shiojima, I.2
-
39
-
-
48249155484
-
Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart
-
Oshima Y, Ouchi N, Sato K, Izumiya Y, Pimentel DR, Walsh K. Follistatin-like 1 is an Akt-regulated cardioprotective factor that is secreted by the heart. Circulation. 2008;117:3099-3108.
-
(2008)
Circulation
, vol.117
, pp. 3099-3108
-
-
Oshima, Y.1
Ouchi, N.2
Sato, K.3
Izumiya, Y.4
Pimentel, D.R.5
Walsh, K.6
-
40
-
-
57749107636
-
Follistatin-like 1, a secreted muscle protein, promotes endo-thelial cell function and revascularization in ischemic tissue through a nitric oxide synthesis-dependent mechanism
-
Ouchi N, Oshima Y, Ohashi K, Higuchi A, Ikegami C, Izumiya Y, Walsh K. Follistatin-like 1, a secreted muscle protein, promotes endo-thelial cell function and revascularization in ischemic tissue through a nitric oxide synthesis-dependent mechanism. J Biol Chem. 2008;283: 32802-32811.
-
(2008)
J Biol Chem
, vol.283
, pp. 32802-32811
-
-
Ouchi, N.1
Oshima, Y.2
Ohashi, K.3
Higuchi, A.4
Ikegami, C.5
Izumiya, Y.6
Walsh, K.7
-
41
-
-
77951216198
-
DIP2A functions as a FSTL1 receptor
-
Ouchi N, Asaumi Y, Ohashi K, Higuchi A, Sono-Romanelli S, Oshima Y, Walsh K. DIP2A functions as a FSTL1 receptor. J Biol Chem. 2010;285:7127-7134.
-
(2010)
J Biol Chem
, vol.285
, pp. 7127-7134
-
-
Ouchi, N.1
Asaumi, Y.2
Ohashi, K.3
Higuchi, A.4
Sono-Romanelli, S.5
Oshima, Y.6
Walsh, K.7
-
42
-
-
14644442283
-
Oxygen, oxidative stress, hypoxia, and heart failure
-
Giordano FJ. Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest. 2005;115:500-508.
-
(2005)
J Clin Invest
, vol.115
, pp. 500-508
-
-
Giordano, F.J.1
-
43
-
-
0035812772
-
HIF-1 O(2), and the 3 PHDs: How animal cells signal hypoxia to the nucleus
-
Semenza GL. HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. Cell. 2001;107:1-3.
-
(2001)
Cell
, vol.107
, pp. 1-3
-
-
Semenza, G.L.1
-
44
-
-
36049037185
-
Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart
-
Heineke J, Auger-Messier M, Xu J, Oka T, Sargent MA, York A, Klevitsky R, Vaikunth S, Duncan SA, Aronow BJ, Robbins J, Crombleholme TM, Molkentin JD. Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart. J Clin Invest. 2007;117:3198-3210.
-
(2007)
J Clin Invest
, vol.117
, pp. 3198-3210
-
-
Heineke, J.1
Auger-Messier, M.2
Xu, J.3
Oka, T.4
Sargent, M.A.5
York, A.6
Klevitsky, R.7
Vaikunth, S.8
Duncan, S.A.9
Aronow, B.J.10
Robbins, J.11
Crombleholme, T.M.12
Molkentin, J.D.13
-
45
-
-
33751260905
-
Hemodynamic effects of intracoronary VEGF delivery: Evidence of tachyphylaxis and NO dependence of response
-
Lopez JJ, Laham RJ, Carrozza JP, Tofukuji M, Sellke FW, Bunting S, Simons M. Hemodynamic effects of intracoronary VEGF delivery: evidence of tachyphylaxis and NO dependence of response. Am J Physiol. 1997;273:H1317-H1323.
-
(1997)
Am J Physiol
, vol.273
-
-
Lopez, J.J.1
Laham, R.J.2
Carrozza, J.P.3
Tofukuji, M.4
Sellke, F.W.5
Bunting, S.6
Simons, M.7
-
46
-
-
57149094838
-
Endothelium as master regulator of organ development and growth
-
Tirziu D, Simons M. Endothelium as master regulator of organ development and growth. Vascul Pharmacol. 2009;50:1-7.
-
(2009)
Vascul Pharmacol
, vol.50
, pp. 1-7
-
-
Tirziu, D.1
Simons, M.2
-
47
-
-
0031924655
-
Coordinated capillary and myocardial growth in response to thyroxine treatment
-
Tomanek RJ, Busch TL. Coordinated capillary and myocardial growth in response to thyroxine treatment. Anat Rec. 1998;251:44-49.
-
(1998)
Anat Rec
, vol.251
, pp. 44-49
-
-
Tomanek, R.J.1
Busch, T.L.2
-
48
-
-
0032559767
-
Early coronary angiogenesis in response to thyroxine: Growth characteristics and upregulation of basic fibroblast growth factor
-
Tomanek RJ, Doty MK, Sandra A. Early coronary angiogenesis in response to thyroxine: growth characteristics and upregulation of basic fibroblast growth factor. Circ Res. 1998;82:587-593.
-
(1998)
Circ Res
, vol.82
, pp. 587-593
-
-
Tomanek, R.J.1
Doty, M.K.2
Sandra, A.3
-
49
-
-
36048999385
-
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice
-
Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. J Clin Invest. 2007;117: 3188-3197.
-
(2007)
J Clin Invest
, vol.117
, pp. 3188-3197
-
-
Tirziu, D.1
Chorianopoulos, E.2
Moodie, K.L.3
Palac, R.T.4
Zhuang, Z.W.5
Tjwa, M.6
Roncal, C.7
Eriksson, U.8
Fu, Q.9
Elfenbein, A.10
Hall, A.E.11
Carmeliet, P.12
Moons, L.13
Simons, M.14
-
50
-
-
63249131125
-
Endothelium-driven myocardial growth or nitric oxide at the crossroads
-
Tirziu D, Simons M. Endothelium-driven myocardial growth or nitric oxide at the crossroads. Trends Cardiovasc Med. 2008;18:299-305.
-
(2008)
Trends Cardiovasc Med
, vol.18
, pp. 299-305
-
-
Tirziu, D.1
Simons, M.2
-
51
-
-
27144557281
-
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
-
Hu RG, Sheng J, Qi X, Xu Z, Takahashi TT, Varshavsky A. The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature. 2005;437:981-986.
-
(2005)
Nature
, vol.437
, pp. 981-986
-
-
Hu, R.G.1
Sheng, J.2
Qi, X.3
Xu, Z.4
Takahashi, T.T.5
Varshavsky, A.6
-
52
-
-
55449118233
-
Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy
-
Karpanen T, Bry M, Ollila HM, Seppanen-Laakso T, Liimatta E, Leskinen H, Kivela R, Helkamaa T, Merentie M, Jeltsch M, Paavonen K, Andersson LC, Mervaala E, Hassinen IE, Yla-Herttuala S, Oresic M, Alitalo K. Overexpression of vascular endothelial growth factor-B in mouse heart alters cardiac lipid metabolism and induces myocardial hypertrophy. Circ Res. 2008;103:1018-1026.
-
(2008)
Circ Res
, vol.103
, pp. 1018-1026
-
-
Karpanen, T.1
Bry, M.2
Ollila, H.M.3
Seppanen-Laakso, T.4
Liimatta, E.5
Leskinen, H.6
Kivela, R.7
Helkamaa, T.8
Merentie, M.9
Jeltsch, M.10
Paavonen, K.11
Andersson, L.C.12
Mervaala, E.13
Hassinen, I.E.14
Yla-Herttuala, S.15
Oresic, M.16
Alitalo, K.17
-
53
-
-
38349138807
-
Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation
-
May D, Gilon D, Djonov V, Itin A, Lazarus A, Gordon O, Rosenberger C, Keshet E. Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation. Proc Natl Acad Sci\USA. 2008;105:282-287.
-
(2008)
Proc Natl Acad Sci\USA
, vol.105
, pp. 282-287
-
-
May, D.1
Gilon, D.2
Djonov, V.3
Itin, A.4
Lazarus, A.5
Gordon, O.6
Rosenberger, C.7
Keshet, E.8
-
54
-
-
33646149385
-
Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload
-
Izumiya Y, Shiojima I, Sato K, Sawyer DB, Colucci WS, Walsh K. Vascular endothelial growth factor blockade promotes the transition from compensatory cardiac hypertrophy to failure in response to pressure overload. Hypertension. 2006;47:887-893.
-
(2006)
Hypertension
, vol.47
, pp. 887-893
-
-
Izumiya, Y.1
Shiojima, I.2
Sato, K.3
Sawyer, D.B.4
Colucci, W.S.5
Walsh, K.6
-
55
-
-
33947520124
-
P53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload
-
Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature. 2007;446:444-448.
-
(2007)
Nature
, vol.446
, pp. 444-448
-
-
Sano, M.1
Minamino, T.2
Toko, H.3
Miyauchi, H.4
Orimo, M.5
Qin, Y.6
Akazawa, H.7
Tateno, K.8
Kayama, Y.9
Harada, M.10
Shimizu, I.11
Asahara, T.12
Hamada, H.13
Tomita, S.14
Molkentin, J.D.15
Zou, Y.16
Komuro, I.17
-
56
-
-
34247572411
-
Myocardial angiogenesis: Its absence makes the growing heart founder
-
Dorn GW II. Myocardial angiogenesis: its absence makes the growing heart founder. Cell Metab. 2007;5:326-327.
-
(2007)
Cell Metab
, vol.5
, pp. 326-327
-
-
Dorn, I.I.G.W.1
-
57
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D, Birchmeier C. Multiple essential functions of neuregulin in development. Nature. 1995;378:386-390.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
58
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
-
Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, Lemke G. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature. 1995;378:390-394.
-
(1995)
Nature
, vol.378
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
Simon, H.4
Lai, C.5
Klein, R.6
Lemke, G.7
-
59
-
-
33745805840
-
Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk
-
Lemmens K, Segers VF, Demolder M, De Keulenaer GW. Role of neuregulin-1/ErbB2 signaling in endothelium-cardiomyocyte cross-talk. J Biol Chem. 2006;281:19469-19477.
-
(2006)
J Biol Chem
, vol.281
, pp. 19469-19477
-
-
Lemmens, K.1
Segers, V.F.2
Demolder, M.3
De Keulenaer, G.W.4
-
60
-
-
34548132413
-
Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: Implications for therapy of heart failure
-
Lemmens K, Doggen K, De Keulenaer GW. Role of neuregulin-1/ErbB signaling in cardiovascular physiology and disease: implications for therapy of heart failure. Circulation. 2007;116:954-960.
-
(2007)
Circulation
, vol.116
, pp. 954-960
-
-
Lemmens, K.1
Doggen, K.2
De Keulenaer, G.W.3
-
61
-
-
0032714208
-
NRG-1-induced cardiomyocyte hypertrophy: Role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK
-
Baliga RR, Pimental DR, Zhao YY, Simmons WW, Marchionni MA, Sawyer DB, Kelly RA. NRG-1-induced cardiomyocyte hypertrophy: role of PI-3-kinase, p70(S6K), and MEK-MAPK-RSK. Am J Physiol. 1999;277:H2026-H2037.
-
(1999)
Am J Physiol
, vol.277
-
-
Baliga, R.R.1
Pimental, D.R.2
Zhao, Y.Y.3
Simmons, W.W.4
Marchionni, M.A.5
Sawyer, D.B.6
Kelly, R.A.7
-
62
-
-
59049093631
-
Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways
-
Gordon LI, Burke MA, Singh AT, Prachand S, Lieberman ED, Sun L, Naik TJ, Prasad SV, Ardehali H. Blockade of the erbB2 receptor induces cardiomyocyte death through mitochondrial and reactive oxygen species-dependent pathways. J Biol Chem. 2009;284:2080-2087.
-
(2009)
J Biol Chem
, vol.284
, pp. 2080-2087
-
-
Gordon, L.I.1
Burke, M.A.2
Singh, A.T.3
Prachand, S.4
Lieberman, E.D.5
Sun, L.6
Naik, T.J.7
Prasad, S.V.8
Ardehali, H.9
-
64
-
-
67650569135
-
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
-
Bersell K, Arab S, Haring B, Kuhn B. Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury. Cell. 2009;138:257-270.
-
(2009)
Cell
, vol.138
, pp. 257-270
-
-
Bersell, K.1
Arab, S.2
Haring, B.3
Kuhn, B.4
-
65
-
-
33750326644
-
Opposing cardiovascular roles for the angiotensin and apelin signaling pathways
-
Ashley E, Chun HJ, Quertermous T. Opposing cardiovascular roles for the angiotensin and apelin signaling pathways. J Mol Cell Cardiol. 2006;41:778-781.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 778-781
-
-
Ashley, E.1
Chun, H.J.2
Quertermous, T.3
-
66
-
-
55849094397
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
-
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest. 2008;118: 3343-3354.
-
(2008)
J Clin Invest
, vol.118
, pp. 3343-3354
-
-
Chun, H.J.1
Ali, Z.A.2
Kojima, Y.3
Kundu, R.K.4
Sheikh, A.Y.5
Agrawal, R.6
Zheng, L.7
Leeper, N.J.8
Pearl, N.E.9
Patterson, A.J.10
Anderson, J.P.11
Tsao, P.S.12
Lenardo, M.J.13
Ashley, E.A.14
Quertermous, T.15
-
67
-
-
38149051165
-
In vivo genetic profiling and cellular localization of apelin reveals a hyp-oxia-sensitive, endothelial-centered pathway activated in ischemic heart failure
-
Sheikh AY, Chun HJ, Glassford AJ, Kundu RK, Kutschka I, Ardigo D, Hendry SL, Wagner RA, Chen MM, Ali ZA, Yue P, Huynh DT, Connolly AJ, Pelletier MP, Tsao PS, Robbins RC, Quertermous T. In vivo genetic profiling and cellular localization of apelin reveals a hyp-oxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol. 2008;294:H88-H98.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Sheikh, A.Y.1
Chun, H.J.2
Glassford, A.J.3
Kundu, R.K.4
Kutschka, I.5
Ardigo, D.6
Hendry, S.L.7
Wagner, R.A.8
Chen, M.M.9
Ali, Z.A.10
Yue, P.11
Huynh, D.T.12
Connolly, A.J.13
Pelletier, M.P.14
Tsao, P.S.15
Robbins, R.C.16
Quertermous, T.17
-
68
-
-
0141615870
-
Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction
-
Chen MM, Ashley EA, Deng DX, Tsalenko A, Deng A, Tabibiazar R, Ben-Dor A, Fenster B, Yang E, King JY, Fowler M, Robbins R, Johnson FL, Bruhn L, McDonagh T, Dargie H, Yakhini Z, Tsao PS, Quertermous T. Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction. Circulation. 2003;108:1432-1439.
-
(2003)
Circulation
, vol.108
, pp. 1432-1439
-
-
Chen, M.M.1
Ashley, E.A.2
Deng, D.X.3
Tsalenko, A.4
Deng, A.5
Tabibiazar, R.6
Ben-Dor, A.7
Fenster, B.8
Yang, E.9
King, J.Y.10
Fowler, M.11
Robbins, R.12
Johnson, F.L.13
Bruhn, L.14
McDonagh, T.15
Dargie, H.16
Yakhini, Z.17
Tsao, P.S.18
Quertermous, T.19
-
69
-
-
1542300876
-
Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endo-cardial endothelial cells
-
Kleinz MJ, Davenport AP. Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endo-cardial endothelial cells. Regul Pept. 2004;118:119-125.
-
(2004)
Regul Pept
, vol.118
, pp. 119-125
-
-
Kleinz, M.J.1
Davenport, A.P.2
-
70
-
-
12344312427
-
Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells
-
Kleinz MJ, Skepper JN, Davenport AP. Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells. Regul Pept. 2005;126:233-240.
-
(2005)
Regul Pept
, vol.126
, pp. 233-240
-
-
Kleinz, M.J.1
Skepper, J.N.2
Davenport, A.P.3
-
71
-
-
3242806007
-
TGF-beta1 and angiotensin networking in cardiac remodeling
-
Rosenkranz S. TGF-beta1 and angiotensin networking in cardiac remodeling. Cardiovasc Res. 2004;63:423-432.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 423-432
-
-
Rosenkranz, S.1
-
72
-
-
0042165829
-
Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
-
Foldes G, Horkay F, Szokodi I, Vuolteenaho O, Ilves M, Lindstedt KA, Mayranpaa M, Sarman B, Seres L, Skoumal R, Lako-Futo Z, deChatel R, Ruskoaho H, Toth M. Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure. Biochem Biophys Res Commun. 2003;308:480-485.
-
(2003)
Biochem Biophys Res Commun
, vol.308
, pp. 480-485
-
-
Foldes, G.1
Horkay, F.2
Szokodi, I.3
Vuolteenaho, O.4
Ilves, M.5
Lindstedt, K.A.6
Mayranpaa, M.7
Sarman, B.8
Seres, L.9
Skoumal, R.10
Lako-Futo, Z.11
Dechatel, R.12
Ruskoaho, H.13
Toth, M.14
-
73
-
-
33744816839
-
Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure
-
Chong KS, Gardner RS, Morton JJ, Ashley EA, McDonagh TA. Plasma concentrations of the novel peptide apelin are decreased in patients with chronic heart failure. Eur J Heart Fail. 2006;8:355-360.
-
(2006)
Eur J Heart Fail
, vol.8
, pp. 355-360
-
-
Chong, K.S.1
Gardner, R.S.2
Morton, J.J.3
Ashley, E.A.4
McDonagh, T.A.5
-
74
-
-
70350462121
-
Endogenous regulation of cardiovascular function by apelin-APJ
-
Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol. 2009;297:H1904-H1913.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Charo, D.N.1
Ho, M.2
Fajardo, G.3
Kawana, M.4
Kundu, R.K.5
Sheikh, A.Y.6
Finsterbach, T.P.7
Leeper, N.J.8
Ernst, K.V.9
Chen, M.M.10
Ho, Y.D.11
Chun, H.J.12
Bernstein, D.13
Ashley, E.A.14
Quertermous, T.15
-
75
-
-
33750301665
-
Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II-angiotensin type 1 receptor system
-
Iwanaga Y, Kihara Y, Takenaka H, Kita T. Down-regulation of cardiac apelin system in hypertrophied and failing hearts: possible role of angiotensin II-angiotensin type 1 receptor system. J Mol Cell Cardiol. 2006;41:798-806.
-
(2006)
J Mol Cell Cardiol
, vol.41
, pp. 798-806
-
-
Iwanaga, Y.1
Kihara, Y.2
Takenaka, H.3
Kita, T.4
-
76
-
-
0034038922
-
Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis
-
MacKenna D, Summerour SR, Villarreal FJ. Role of mechanical factors in modulating cardiac fibroblast function and extracellular matrix synthesis. Cardiovasc Res. 2000;46:257-263.
-
(2000)
Cardiovasc Res
, vol.46
, pp. 257-263
-
-
MacKenna, D.1
Summerour, S.R.2
Villarreal, F.J.3
-
77
-
-
0036950082
-
Gene expression in fibroblasts and fibrosis: Involvement in cardiac hypertrophy
-
Manabe I, Shindo T, Nagai R. Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy. Circ Res. 2002;91: 1103-1113.
-
(2002)
Circ Res
, vol.91
, pp. 1103-1113
-
-
Manabe, I.1
Shindo, T.2
Nagai, R.3
-
78
-
-
34047148354
-
The role of TGF-beta signaling in myo-cardial infarction and cardiac remodeling
-
Bujak M, Frangogiannis NG. The role of TGF-beta signaling in myo-cardial infarction and cardiac remodeling. Cardiovasc Res. 2007;74: 184-195.
-
(2007)
Cardiovasc Res
, vol.74
, pp. 184-195
-
-
Bujak, M.1
Frangogiannis, N.G.2
-
79
-
-
0036159503
-
Is angiotensin II a proliferative factor of cardiac fibroblasts?
-
Bouzegrhane F, Thibault G. Is angiotensin II a proliferative factor of cardiac fibroblasts? Cardiovasc Res. 2002;53:304-312.
-
(2002)
Cardiovasc Res
, vol.53
, pp. 304-312
-
-
Bouzegrhane, F.1
Thibault, G.2
-
80
-
-
0036277026
-
Myofi-broblasts and mechano-regulation of connective tissue remodelling
-
Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. Myofi-broblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol. 2002;3:349-363.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 349-363
-
-
Tomasek, J.J.1
Gabbiani, G.2
Hinz, B.3
Chaponnier, C.4
Brown, R.A.5
-
81
-
-
34547676391
-
Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
-
Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med. 2007;13:952-961.
-
(2007)
Nat Med
, vol.13
, pp. 952-961
-
-
Zeisberg, E.M.1
Tarnavski, O.2
Zeisberg, M.3
Dorfman, A.L.4
McMullen, J.R.5
Gustafsson, E.6
Chandraker, A.7
Yuan, X.8
Pu, W.T.9
Roberts, A.B.10
Neilson, E.G.11
Sayegh, M.H.12
Izumo, S.13
Kalluri, R.14
-
82
-
-
55249126800
-
The role of endothelial-to-mesenchymal transition in cancer progression
-
Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer. 2008;99: 1375-1379.
-
(2008)
Br J Cancer
, vol.99
, pp. 1375-1379
-
-
Potenta, S.1
Zeisberg, E.2
Kalluri, R.3
-
83
-
-
0033745462
-
CTGF expression is induced by TGF-beta in cardiac fibroblasts and cardiac myocytes: A potential role in heart fibrosis
-
Chen MM, Lam A, Abraham JA, Schreiner GF, Joly AH. CTGF expression is induced by TGF-beta in cardiac fibroblasts and cardiac myocytes: a potential role in heart fibrosis. J Mol Cell Cardiol. 2000; 32:1805-1819.
-
(2000)
J Mol Cell Cardiol
, vol.32
, pp. 1805-1819
-
-
Chen, M.M.1
Lam, A.2
Abraham, J.A.3
Schreiner, G.F.4
Joly, A.H.5
-
84
-
-
59849128881
-
Creemers EE. miR-133 and miR-30 regulate connective tissue growth factor: Implications for a role of microRNAs in myocardial matrix remodeling
-
Duisters RF, Tijsen AJ, Schroen B, Leenders JJ, Lentink V, van der Made I, Herias V, van Leeuwen RE, Schellings MW, Barenbrug P, Maessen JG, Heymans S, Pinto YM, Creemers EE. miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling. Circ Res. 2009;104: 170-178.
-
(2009)
Circ Res
, vol.104
, pp. 170-178
-
-
Duisters, R.F.1
Tijsen, A.J.2
Schroen, B.3
Leenders, J.J.4
Lentink, V.5
Van Der Made, I.6
Herias, V.7
Van Leeuwen, R.E.8
Schellings, M.W.9
Barenbrug, P.10
Maessen, J.G.11
Heymans, S.12
Pinto, Y.M.13
-
85
-
-
34249279050
-
MicroRNA-133 controls cardiac hypertrophy
-
Care A, Catalucci D, Felicetti F, Bonci D, Addario A, Gallo P, Bang ML, Segnalini P, Gu Y, Dalton ND, Elia L, Latronico MV, Hoydal M, Autore C, Russo MA, Dorn GW II, Ellingsen O, Ruiz-Lozano P, Peterson KL, Croce CM, Peschle C, Condorelli G. MicroRNA-133 controls cardiac hypertrophy. Nat Med. 2007;13:613-618.
-
(2007)
Nat Med
, vol.13
, pp. 613-618
-
-
Care, A.1
Catalucci, D.2
Felicetti, F.3
Bonci, D.4
Addario, A.5
Gallo, P.6
Bang, M.L.7
Segnalini, P.8
Gu, Y.9
Dalton, N.D.10
Elia, L.11
Latronico, M.V.12
Hoydal, M.13
Autore, C.14
Russo, M.A.15
Dorn, G.W.I.I.16
Ellingsen, O.17
Ruiz-Lozano, P.18
Peterson, K.L.19
Croce, C.M.20
Peschle, C.21
Condorelli, G.22
more..
-
86
-
-
59849114044
-
Searching for miR-acles in cardiac fibrosis
-
van Rooij E, Olson EN. Searching for miR-acles in cardiac fibrosis. Circ Res. 2009;104:138-140.
-
(2009)
Circ Res
, vol.104
, pp. 138-140
-
-
Van Rooij, E.1
Olson, E.N.2
-
87
-
-
59649110883
-
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling
-
Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009;16:233-244.
-
(2009)
Dev Cell
, vol.16
, pp. 233-244
-
-
Ieda, M.1
Tsuchihashi, T.2
Ivey, K.N.3
Ross, R.S.4
Hong, T.T.5
Shaw, R.M.6
Srivastava, D.7
-
88
-
-
63849307598
-
Integrins and proximal signaling mechanisms in cardiovascular disease
-
Lal H, Verma SK, Foster DM, Golden HB, Reneau JC, Watson LE, Singh H, Dostal DE. Integrins and proximal signaling mechanisms in cardiovascular disease. Front Biosci. 2009;14:2307-2334.
-
(2009)
Front Biosci
, vol.14
, pp. 2307-2334
-
-
Lal, H.1
Verma, S.K.2
Foster, D.M.3
Golden, H.B.4
Reneau, J.C.5
Watson, L.E.6
Singh, H.7
Dostal, D.E.8
-
89
-
-
0032525330
-
Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes
-
Ross RS, Pham C, Shai SY, Goldhaber JI, Fenczik C, Glembotski CC, Ginsberg MH, Loftus JC. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circ Res. 1998;82:1160-1172.
-
(1998)
Circ Res
, vol.82
, pp. 1160-1172
-
-
Ross, R.S.1
Pham, C.2
Shai, S.Y.3
Goldhaber, J.I.4
Fenczik, C.5
Glembotski, C.C.6
Ginsberg, M.H.7
Loftus, J.C.8
-
90
-
-
0037040839
-
Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure
-
Shai SY, Harpf AE, Babbitt CJ, Jordan MC, Fishbein MC, Chen J, Omura M, Leil TA, Becker KD, Jiang M, Smith DJ, Cherry SR, Loftus JC, Ross RS. Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure. Circ Res. 2002; 90:458-464.
-
(2002)
Circ Res
, vol.90
, pp. 458-464
-
-
Shai, S.Y.1
Harpf, A.E.2
Babbitt, C.J.3
Jordan, M.C.4
Fishbein, M.C.5
Chen, J.6
Omura, M.7
Leil, T.A.8
Becker, K.D.9
Jiang, M.10
Smith, D.J.11
Cherry, S.R.12
Loftus, J.C.13
Ross, R.S.14
-
91
-
-
54449101472
-
Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways
-
Marin TM, Clemente CF, Santos AM, Picardi PK, Pascoal VD, Lopes-Cendes I, Saad MJ, Franchini KG. Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways. Circ Res. 2008;103:813-824.
-
(2008)
Circ Res
, vol.103
, pp. 813-824
-
-
Marin, T.M.1
Clemente, C.F.2
Santos, A.M.3
Picardi, P.K.4
Pascoal, V.D.5
Lopes-Cendes, I.6
Saad, M.J.7
Franchini, K.G.8
-
92
-
-
54449102057
-
Shp shape: FAKs about hypertrophy
-
Martin KA, Hwa J. Shp shape: FAKs about hypertrophy. Circ Res. 2008;103:776-778.
-
(2008)
Circ Res
, vol.103
, pp. 776-778
-
-
Martin, K.A.1
Hwa, J.2
-
93
-
-
70349678681
-
Cdc42 is an antihypertrophic molecular switch in the mouse heart
-
Maillet M, Lynch JM, Sanna B, York AJ, Zheng Y, Molkentin JD. Cdc42 is an antihypertrophic molecular switch in the mouse heart. J Clin Invest. 2009;119:3079-3088.
-
(2009)
J Clin Invest
, vol.119
, pp. 3079-3088
-
-
Maillet, M.1
Lynch, J.M.2
Sanna, B.3
York, A.J.4
Zheng, Y.5
Molkentin, J.D.6
-
94
-
-
66949126859
-
Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth
-
DiMichele LA, Hakim ZS, Sayers RL, Rojas M, Schwartz RJ, Mack CP, Taylor JM. Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth. Circ Res. 2009;104:1201-1208.
-
(2009)
Circ Res
, vol.104
, pp. 1201-1208
-
-
Dimichele, L.A.1
Hakim, Z.S.2
Sayers, R.L.3
Rojas, M.4
Schwartz, R.J.5
MacK, C.P.6
Taylor, J.M.7
-
95
-
-
0037236642
-
Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload
-
Brancaccio M, Fratta L, Notte A, Hirsch E, Poulet R, Guazzone S, De Acetis M, Vecchione C, Marino G, Altruda F, Silengo L, Tarone G, Lembo G. Melusin, a muscle-specific integrin beta1-interacting protein, is required to prevent cardiac failure in response to chronic pressure overload. Nat Med. 2003;9:68-75.
-
(2003)
Nat Med
, vol.9
, pp. 68-75
-
-
Brancaccio, M.1
Fratta, L.2
Notte, A.3
Hirsch, E.4
Poulet, R.5
Guazzone, S.6
De Acetis, M.7
Vecchione, C.8
Marino, G.9
Altruda, F.10
Silengo, L.11
Tarone, G.12
Lembo, G.13
-
96
-
-
3242753503
-
Molecular and mechanical synergy: Cross-talk between integrins and growth factor receptors
-
Ross RS. Molecular and mechanical synergy: cross-talk between integrins and growth factor receptors. Cardiovasc Res. 2004;63: 381-390.
-
(2004)
Cardiovasc Res
, vol.63
, pp. 381-390
-
-
Ross, R.S.1
-
97
-
-
0035205153
-
Upregulation of alpha(8)beta(1)-integrin in cardiac fibroblast by angiotensin II and transforming growth factor-beta1
-
Thibault G, Lacombe MJ, Schnapp LM, Lacasse A, Bouzeghrane F, Lapalme G. Upregulation of alpha(8)beta(1)-integrin in cardiac fibroblast by angiotensin II and transforming growth factor-beta1. Am J Physiol Cell Physiol. 2001;281:C1457-C1467.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Thibault, G.1
Lacombe, M.J.2
Schnapp, L.M.3
Lacasse, A.4
Bouzeghrane, F.5
Lapalme, G.6
-
98
-
-
0033617339
-
Control of type II transforming growth factor-beta receptor expression by integrin ligation
-
Wang D, Sun L, Zborowska E, Willson JK, Gong J, Verraraghavan J, Brattain MG. Control of type II transforming growth factor-beta receptor expression by integrin ligation. J Biol Chem. 1999;274:12840-12847.
-
(1999)
J Biol Chem
, vol.274
, pp. 12840-12847
-
-
Wang, D.1
Sun, L.2
Zborowska, E.3
Willson, J.K.4
Gong, J.5
Verraraghavan, J.6
Brattain, M.G.7
-
99
-
-
48749126205
-
Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy
-
Dallabrida SM, Ismail NS, Pravda EA, Parodi EM, Dickie R, Durand EM, Lai J, Cassiola F, Rogers RA, Rupnick MA. Integrin binding angiopoietin-1 monomers reduce cardiac hypertrophy. FASEB J. 2008; 22:3010-3023.
-
(2008)
FASEB J
, vol.22
, pp. 3010-3023
-
-
Dallabrida, S.M.1
Ismail, N.S.2
Pravda, E.A.3
Parodi, E.M.4
Dickie, R.5
Durand, E.M.6
Lai, J.7
Cassiola, F.8
Rogers, R.A.9
Rupnick, M.A.10
-
100
-
-
0036152858
-
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
-
Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, Yoshinaka T, Ohmoto H, Node K, Yoshino K, Ishiguro H, Asanuma H, Sanada S, Matsumura Y, Takeda H, Beppu S, Tada M, Hori M, Higashiyama S. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nat Med. 2002;8:35-40.
-
(2002)
Nat Med
, vol.8
, pp. 35-40
-
-
Asakura, M.1
Kitakaze, M.2
Takashima, S.3
Liao, Y.4
Ishikura, F.5
Yoshinaka, T.6
Ohmoto, H.7
Node, K.8
Yoshino, K.9
Ishiguro, H.10
Asanuma, H.11
Sanada, S.12
Matsumura, Y.13
Takeda, H.14
Beppu, S.15
Tada, M.16
Hori, M.17
Higashiyama, S.18
-
103
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med. 2004;10:1384-1389.
-
(2004)
Nat Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
104
-
-
3142616447
-
Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of AMP-activated protein kinase signaling
-
DOI 10.1074/jbc.M402558200
-
Shibata R, Ouchi N, Kihara S, Sato K, Funahashi T, Walsh K. Adiponectin stimulates angiogenesis in response to tissue ischemia through stimulation of amp-activated protein kinase signaling. J Biol Chem. 2004;279:28670-28674. (Pubitemid 38900150)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.27
, pp. 28670-28674
-
-
Shibata, R.1
Ouchi, N.2
Kihara, S.3
Sato, K.4
Funahashi, T.5
Walsh, K.6
-
105
-
-
25444506344
-
Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure
-
Kistorp C, Faber J, Galatius S, Gustafsson F, Frystyk J, Flyvbjerg A, Hildebrandt P. Plasma adiponectin, body mass index, and mortality in patients with chronic heart failure. Circulation. 2005;112:1756-1762.
-
(2005)
Circulation
, vol.112
, pp. 1756-1762
-
-
Kistorp, C.1
Faber, J.2
Galatius, S.3
Gustafsson, F.4
Frystyk, J.5
Flyvbjerg, A.6
Hildebrandt, P.7
-
106
-
-
1842864234
-
Plasma adiponectin levels and risk of myocardial infarction in men
-
Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA. 2004;291:1730-1737.
-
(2004)
JAMA
, vol.291
, pp. 1730-1737
-
-
Pischon, T.1
Girman, C.J.2
Hotamisligil, G.S.3
Rifai, N.4
Hu, F.B.5
Rimm, E.B.6
-
107
-
-
12744269196
-
Adiponectin and future coronary heart disease events among men with type 2 diabetes
-
Schulze MB, Shai I, Rimm EB, Li T, Rifai N, Hu FB. Adiponectin and future coronary heart disease events among men with type 2 diabetes. Diabetes. 2005;54:534-539.
-
(2005)
Diabetes
, vol.54
, pp. 534-539
-
-
Schulze, M.B.1
Shai, I.2
Rimm, E.B.3
Li, T.4
Rifai, N.5
Hu, F.B.6
-
108
-
-
0037300425
-
Adrenomedullin: A possible autocrine or paracrine hormone in the cardiac ventricles
-
Kato J, Tsuruda T, Kitamura K, Eto T. Adrenomedullin: a possible autocrine or paracrine hormone in the cardiac ventricles. Hypertens Res. 2003;26(suppl):S113-S119.
-
(2003)
Hypertens Res
, vol.26
, Issue.SUPPL.
-
-
Kato, J.1
Tsuruda, T.2
Kitamura, K.3
Eto, T.4
-
109
-
-
40349100269
-
Intermedin (adrenomedullin-2): A novel counter-regulatory peptide in the cardiovascular and renal systems
-
Bell D, McDermott BJ. Intermedin (adrenomedullin-2): a novel counter-regulatory peptide in the cardiovascular and renal systems. Br J Pharmacol. 2008;153(suppl 1):S247-S262.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Bell, D.1
McDermott, B.J.2
-
110
-
-
22144492268
-
Cardiac adrenomedullin: Its role in cardiac hypertrophy and heart failure
-
Nishikimi T, Matsuoka H. Cardiac adrenomedullin: its role in cardiac hypertrophy and heart failure. Curr Med Chem Cardiovasc Hematol Agents. 2005;3:231-242.
-
(2005)
Curr Med Chem Cardiovasc Hematol Agents
, vol.3
, pp. 231-242
-
-
Nishikimi, T.1
Matsuoka, H.2
-
111
-
-
38149140953
-
The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity
-
Ichikawa-Shindo Y, Sakurai T, Kamiyoshi A, Kawate H, Iinuma N, Yoshizawa T, Koyama T, Fukuchi J, Iimuro S, Moriyama N, Kawakami H, Murata T, Kangawa K, Nagai R, Shindo T. The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity. J Clin Invest. 2008;118:29-39.
-
(2008)
J Clin Invest
, vol.118
, pp. 29-39
-
-
Ichikawa-Shindo, Y.1
Sakurai, T.2
Kamiyoshi, A.3
Kawate, H.4
Iinuma, N.5
Yoshizawa, T.6
Koyama, T.7
Fukuchi, J.8
Iimuro, S.9
Moriyama, N.10
Kawakami, H.11
Murata, T.12
Kangawa, K.13
Nagai, R.14
Shindo, T.15
-
112
-
-
33746359354
-
Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders
-
Ishimitsu T, Ono H, Minami J, Matsuoka H. Pathophysiologic and therapeutic implications of adrenomedullin in cardiovascular disorders. Pharmacol Ther. 2006;111:909-927.
-
(2006)
Pharmacol Ther
, vol.111
, pp. 909-927
-
-
Ishimitsu, T.1
Ono, H.2
Minami, J.3
Matsuoka, H.4
-
113
-
-
51349169372
-
Increased expression of adrenomedullin 2/intermedin in rat hearts with congestive heart failure
-
Hirose T, Totsune K, Mori N, Morimoto R, Hashimoto M, Nakashige Y, Metoki H, Asayama K, Kikuya M, Ohkubo T, Hashimoto J, Sasano H, Kohzuki M, Takahashi K, Imai Y. Increased expression of adrenomedullin 2/intermedin in rat hearts with congestive heart failure. Eur J Heart Fail. 2008;10:840-849.
-
(2008)
Eur J Heart Fail
, vol.10
, pp. 840-849
-
-
Hirose, T.1
Totsune, K.2
Mori, N.3
Morimoto, R.4
Hashimoto, M.5
Nakashige, Y.6
Metoki, H.7
Asayama, K.8
Kikuya, M.9
Ohkubo, T.10
Hashimoto, J.11
Sasano, H.12
Kohzuki, M.13
Takahashi, K.14
Imai, Y.15
|