Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 4, 2013, Pages

  Zhao, Xiangmin ^a   Zhang, Wei ^a   Xing, Dongqi ^a   Li, Peng ^b   Fu, Jinyan ^a   Gong, Kaizheng ^c   Hage, Fadi G ^a   Oparil, Suzanne ^a   Chen, Yiu Fai ^a  

^a University of Alabama at Birmingham and Birmingham Veterans Affairs Medical Center   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c YANGZHOU UNIVERSITY   (China)

Author keywords

Cell therapy; Endothelial cells; Interleukin 8 receptors; Myocardial infarction; Neovascularization

Indexed keywords

ADENOVIRUS VECTOR; CD31 ANTIGEN; COLLAGEN; CYTOKINE; DYE; INTERLEUKIN 8 RECEPTOR; INTERLEUKIN 8 RECEPTOR A; INTERLEUKIN 8 RECEPTOR B; INTERLEUKIN RECEPTOR; MYELOPEROXIDASE; PICROSIRUS RED; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CELL MEMBRANE; CELL THERAPY; CONTROLLED STUDY; CORONARY ARTERY LIGATION; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; GENE OVEREXPRESSION; HEART; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE; HEART LEFT VENTRICLE FAILURE; HEART VENTRICLE REMODELING; IMMUNOHISTOCHEMISTRY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NEOVASCULARIZATION (PATHOLOGY); NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STAINING; VIRAL GENE DELIVERY SYSTEM;

CELL THERAPY; ENDOTHELIAL CELLS; INTERLEUKIN-8 RECEPTORS; MYOCARDIAL INFARCTION; NEOVASCULARIZATION;

ADENOVIRIDAE; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENETIC THERAPY; GENETIC VECTORS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; NEOVASCULARIZATION, PHYSIOLOGIC; NEUTROPHIL INFILTRATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-8; RECOMBINANT FUSION PROTEINS; TIME FACTORS; TRANSDUCTION, GENETIC; TRANSFECTION; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84881651936     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00571.2012     Document Type: Article

References (38)

1. Abdel-Latif A, Bolli R, Tleyjeh IM, Montori VM, Perin EC, Hornung CA, Zuba-Surma EK, Al-Mallah M, Dawn B. Adult bone marrowderived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 167: 989-997, 2007.
2. Armiñán A, Gandía C, García-Verdugo JM, Lledó E, Trigueros C, Ruiz-Saurí A, Miñana MD, Solves P, Payá R, Montero JA, Sepúlveda P. Mesenchymal stem cells provide better results than hematopoietic precursors for the treatment of myocardial infarction. J Am Coll Cardiol 55: 2244-2253, 2010.
3. Bai X, Wang X, Xu Q. Endothelial damage and stem cell repair in atherosclerosis. Vascul Pharmacol 52: 224-229, 2010.
4. Bolli R, Chugh AR, D'Amario D, Loughran JH, Stoddard MF, Ikram S, Beache GM, Wagner SG, Leri A, Hosoda T, Sanada F, Elmore JB, Goichberg P, Cappetta D, Solankhi NK, Fahsah I, Rokosh DG, Slaughter MS, Kajstura J, Anversa P. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomized phase 1 trial. Lancet 378: 1847-1857, 2011.
5. Carvalho JL, Braga VB, Melo MB, Campos AC, Oliveira MS, Gomes DA, Ferreira AJ, Santos RA, Goes AM. Priming mesenchymal stem cells boosts stem cell therapy to treat myocardial infarction. J Cell Mol Med. In press.
6. Chacko SM, Khan M, Kuppusamy ML, Pandian RP, Varadharaj S, Selvendiran K, Bratasz A, Rivera BK, Kuppusamy P. Myocardial oxygenation and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells. Am J Physiol Heart Circ Physiol 296: H1263-H1273, 2009.
7. Chen Y, Fu L, Han Y, Teng Y, Sun J, Xie R, Cao J. Testosterone replacement therapy promotes angiogenesis after acute myocardial infarction by enhancing expression of cytokines HIF-1a, SDF-1a and VEGF. Eur J Pharmacol 684: 116-124, 2012.
8. Faber JE. Reprogrammed endothelial cells: cell therapy for coronary collateral growth? Circ Res 110: 192-194, 2012.
9. Fan X, Patera AC, Pong-Kennedy A, Deno G, Gonsiorek W, Manfra DJ, Vassileva G, Zeng M, Jackson C, Sullivan L, Sharif-Rodriguez W, Opdenakker G, Van Damme J, Hedrick JA, Lundell D, Lira SA, Hipkin RW. Murine CXCR1 is a functional receptor for GCP-2/CXCL6 and interleukin-8/CXCL8. J Biol Chem 82: 11658-11666, 2007.
10. Feng JA, Perry G, Mori T, Hayashi T, Oparil S, Chen YF. Pressureindependent enhancement of cardiac hypertrophy in atrial natriuretic peptide-deficient mice. Clin Exp Pharmacol Physiol 30: 343-349, 2003.
11. Gao L, Yin H, Smith R S Jr, Chao L, Chao J. Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarction. Lab Invest 88: 1157-1166, 2008.
12. Hinkel R, Trenkwalder T, Kupatt C. Gene therapy for ischemic heart disease. Curr Vasc Pharmacol 9: 124-127, 2011.
13. Hirsch A, Nijveldt R, van der Vleuten PA, Tijssen JG, van der Giessen WJ, Tio RA, Waltenberger J, ten Berg JM, Doevendans PA, Aengevaeren WR, Zwaginga JJ, Biemond BJ, van Rossum AC, Piek JJ, Zijlstra F, Investigators HEBE. Intracoronary infusion of mononuclear cells from bone marrow or peripheral blood compared with standard therapy in patients after acute myocardial infarction treated by primary percutaneous coronary intervention: results of the randomized controlled HEBE trial. Eur Heart J 32: 1736-1747, 2011.
14. Ionita MG, van den Borne P, Catanzariti LM, Moll FL, de Vries JP, Pasterkamp G, Vink A, de Kleijn DP. High neutrophil numbers in human carotid atherosclerotic plaques are associated with characteristics of rupture-prone lesions. Arterioscler Thromb Vasc Biol 30: 1842-1848, 2010.
15. Johnston PV, Sasano T, Mills K, Evers R, Lee ST, Smith RR, Lardo AC, Lai S, Steenbergen C, Gerstenblith G, Lange R, Marbán E. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 120: 1075-1083, 2009.
16. Kanashiro-Takeuchi RM, Takeuchi LM, Rick FG, Dulce R, Treuer AV, Florea V, Rodrigues CO, Paulino EC, Hatzistergos KE, Selem SM, Gonzalez DR, Block NL, Schally AV, Hare JM. Activation of growth hormone releasing hormone (GHRH) receptor stimulates cardiac reverse remodeling after myocardial infarction (MI). Proc Natl Acad Sci USA 109: 559-563, 2012.
17. Lauer MS. Advancing cardiovascular research. Chest 141: 500-505, 2012.
18. Lucas JA, Zhang Y, Li P, Gong K, Miller AP, Hassan E, Hage F, Xing D, Wells B, Oparil S, Chen YF. Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart. Am J Physiol Heart Circ Physiol 298: H424-H432, 2010.
19. Madonna R, De Caterina R. Stem cells and growth factor delivery systems for cardiovascular disease. J Biotechnol 154: 291-297, 2011.
20. Masuda S. Cardiac stem cells in patients with ischaemic cardiomyopathy. Lancet 379: 891-892, 2012.
21. Mewton N, Elbaz M, Piot C, Ovize M. Infarct size reduction in patients with STEMI: why we can do it! J Cardiovasc Pharmacol Ther 16: 298-303, 2011.
22. Mozid AM, Arnous S, Sammut EC, Mathur A. Stem cell therapy for heart diseases. Br Med Bull 98: 143-159, 2011.
23. 2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism. Am J Hypertens 3: 179S-188S, 1990.
24. -/- mice. Am J Pathol 177: 493-500, 2010.
25. Schuh A, Liehn EA, Sasse A, Hristov M, Sobota R, Kelm M, Merx MW, Weber C. Transplantation of endothelial progenitor cells improves neovascularization and left ventricular function after myocardial infarction in a rat model. Basic Res Cardiol 103: 69-77, 2008.
26. Schulman IH, Hare JM. Key developments in stem cell therapy in cardiology. Regen Med 7: 17-24, 2012.
27. Skelton NJ, Quan C, Reilly D, Lowman H. Structure of a CXC chemokine-receptor fragment in complex with interleukin-8. Structure 7: 157-168, 1999.
28. Snelgrove RJ. Targeting of a common receptor shared by CXCL8 and N-Ac-PGP as a therapeutic strategy to alleviate chronic neutrophilic lung diseases. Eur J Pharmacol 667: 1-5, 2011.
29. Stillie R, Farooq SM, Gordon JR, Stadnyk AW. The functional significance behind expressing two IL-8 receptor types on PMN. J Leukoc Biol 86: 529-543, 2009.
30. Sürder D, Manka R, Lo Cicero V, Moccetti T, Rufibach K, Soncin S, Turchetto L, Radrizzani M, Astori G, Schwitter J, Erne P, Zuber M, Auf der Maur C, Jamshidi P, Gaemperli O, Windecker S, Moschovitis A, Wahl A, Bühler I, Wyss C, Kozerke S, Landmesser U, Lüscher TF, Corti R. Intracoronary injection of bone marrow-derived mononuclear cells early or late after acute myocardial infarction: effects on global left ventricular function. Circulation 127: 1968-1979, 2013.
31. Tang XL, Rokosh DG, Guo Y, Bolli R. Cardiac progenitor cells and bone marrow-derived very small embryonic-like stem cells for cardiac repair after myocardial infarction. Circ J 74: 390-404, 2010.
32. Tang XL, Rokosh G, Sanganalmath SK, Yuan F, Sato H, Mu J, Dai S, Li C, Chen N, Peng Y, Dawn B, Hunt G, Leri A, Kajstura J, Tiwari S, Shirk G, Anversa P, Bolli R. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 121: 293-305, 2010.
33. Tongers J, Losordo DW, Landmesser U. Stem and progenitor cell-based therapy in ischaemic heart disease: promise, uncertainties, and challenges. Eur Heart J 32: 1197-1206, 2011.
34. Wang Y, Zhang G, Hou Y, Chen J, Wang J, Zou C, Li D, Li H, Zhang Q, Wang A, Fan Q. Transplantation of microencapsulated Schwann cells and mesenchymal stem cells augment angiogenesis and improve heart function. Mol Cell Biochem 366: 139-147, 2012.
35. Xing D, Li Gong K P, Yu H, Yang Z, Hage F, Oparil S, Chen YF. Endothelial cells overexpressing interleukin-8 (IL8) receptors reduce inflammatory and neointimal responses to arterial injury. Circulation 125: 1533-1541, 2012.
36. Yao Y, Sheng Z, Li Y, Yan F, Ma G, Liu N, Fu C, Li Y, Chao J, Chao L. Tissue kallikrein promotes cardiac neovascularization by enhancing endothelial progenitor cell functional capacity. Hum Gene Ther 23: 859-870, 2012.
37. Yndestad A, Damås JK, Øie E, Ueland T, Gullestad L, Aukrust P. Role of inflammation in the progression of heart failure. Curr Cardiol Rep 9: 236-241, 2007.
38. Zhao T, Zhao W, Chen Y, Ahokas RA, Sun Y. Vascular endothelial growth factor (VEGF)-A: role on cardiac angiogenesis following myocardial infarction. Microvasc Res 80: 188-194, 2010.