-
1
-
-
0034612380
-
Mouse numb is an essential gene involved in cortical neurogenesis
-
Zhong W, Jiang MM, Schonemann MD, Meneses JJ, Pedersen RA, Jan LY et al. Mouse numb is an essential gene involved in cortical neurogenesis. Proc Natl Acad Sci USA 2000; 97: 6844-6849
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 6844-6849
-
-
Zhong, W.1
Jiang, M.M.2
Schonemann, M.D.3
Meneses, J.J.4
Pedersen, R.A.5
Jan, L.Y.6
-
2
-
-
0035799303
-
Multiple roles of mouse Numb in tuning developmental cell fates
-
Zilian O, Saner C, Hagedorn L, Lee HY, Säuberli E, Suter U et al. Multiple roles of mouse Numb in tuning developmental cell fates. Curr Biol 2001; 11: 494-501
-
(2001)
Curr Biol
, vol.11
, pp. 494-501
-
-
Zilian, O.1
Saner, C.2
Hagedorn, L.3
Lee, H.Y.4
Säuberli, E.5
Suter, U.6
-
3
-
-
0024980213
-
Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
-
Uemura T, Shepherd S, Ackerman L, Jan LY, Jan YN. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 1989; 58: 349-360
-
(1989)
Cell
, vol.58
, pp. 349-360
-
-
Uemura, T.1
Shepherd, S.2
Ackerman, L.3
Jan, L.Y.4
Jan, Y.N.5
-
4
-
-
0027947609
-
Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
-
Rhyu MS, Jan LY, Jan YN. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 1994; 76: 477-491
-
(1994)
Cell
, vol.76
, pp. 477-491
-
-
Rhyu, M.S.1
Jan, L.Y.2
Jan, Y.N.3
-
5
-
-
0033595679
-
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling
-
Sestan N, Artavanis-Tsakonas S, Rakic P. Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science 1999; 286: 741-746
-
(1999)
Science
, vol.286
, pp. 741-746
-
-
Sestan, N.1
Artavanis-Tsakonas, S.2
Rakic, P.3
-
6
-
-
0037663379
-
Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
-
McGill MA, McGlade CJ. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J Biol Chem 2003; 278: 23196-23203
-
(2003)
J Biol Chem
, vol.278
, pp. 23196-23203
-
-
McGill, M.A.1
McGlade, C.J.2
-
7
-
-
0036533568
-
Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification
-
French MB, Koch U, Shaye RE, McGill MA, Dho SE, Guidos CJ et al. Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification. J Immun 2002; 168: 3173-3180
-
(2002)
J Immun
, vol.168
, pp. 3173-3180
-
-
French, M.B.1
Koch, U.2
Shaye, R.E.3
McGill, M.A.4
Dho, S.E.5
Guidos, C.J.6
-
8
-
-
0032771052
-
Notch1 inhibits neurite outgrowth in postmitotic primary neurons
-
Berezovska O, McLean P, Knowles R, Frosh M, Lu FM, Lux SE et al. Notch1 inhibits neurite outgrowth in postmitotic primary neurons. Neuroscience 1999; 93: 433-439
-
(1999)
Neuroscience
, vol.93
, pp. 433-439
-
-
Berezovska, O.1
McLean, P.2
Knowles, R.3
Frosh, M.4
Lu, F.M.5
Lux, S.E.6
-
9
-
-
70350374350
-
Numb regulates post-endocytic trafficking and degradation of Notch1
-
McGill MA, Dho SE, Weinmaster G, McGlade CJ. Numb regulates post-endocytic trafficking and degradation of Notch1. J Biol Chem 2009; 284: 26427-26438
-
(2009)
J Biol Chem
, vol.284
, pp. 26427-26438
-
-
McGill, M.A.1
Dho, S.E.2
Weinmaster, G.3
McGlade, C.J.4
-
10
-
-
80052233722
-
Numb controls E-cadherin endocytosis through p120 catenin with aPKC
-
Sato K, Watanabe T, Wang S, Kakeno M, Matsuzawa K, Matsui T et al. Numb controls E-cadherin endocytosis through p120 catenin with aPKC. Mol Biol Cell 2011; 22: 3103-3119
-
(2011)
Mol Biol Cell
, vol.22
, pp. 3103-3119
-
-
Sato, K.1
Watanabe, T.2
Wang, S.3
Kakeno, M.4
Matsuzawa, K.5
Matsui, T.6
-
11
-
-
34250820373
-
Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3
-
Nishimura T, Kaibuchi K. Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev Cell 2007; 13: 15-28
-
(2007)
Dev Cell
, vol.13
, pp. 15-28
-
-
Nishimura, T.1
Kaibuchi, K.2
-
12
-
-
34347359603
-
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors
-
Rašin M-R, Gazula V-R, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S et al. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci 2007; 10: 819-827
-
(2007)
Nat Neurosci
, vol.10
, pp. 819-827
-
-
Rašin, M.-R.1
Gazula, V.-R.2
Breunig, J.J.3
Kwan, K.Y.4
Johnson, M.B.5
Liu-Chen, S.6
-
13
-
-
0034638843
-
Numb is an endocytic protein
-
Santolini E, Puri C, Salcini AE, Gagliani MC, Pelicci PG, Tacchetti C et al. Numb is an endocytic protein. J Cell Biol 2000; 151: 1345-1352
-
(2000)
J Cell Biol
, vol.151
, pp. 1345-1352
-
-
Santolini, E.1
Puri, C.2
Salcini, A.E.3
Gagliani, M.C.4
Pelicci, P.G.5
Tacchetti, C.6
-
14
-
-
33748298775
-
Dynamic regulation of mammalian Numb by G protein-coupled receptors and protein kinase C activation: Structural determinants of Numb association with the cortical membrane
-
Dho SE, Trejo J, Siderovski DP, McGlade CJ. Dynamic regulation of mammalian Numb by G protein-coupled receptors and protein kinase C activation: structural determinants of Numb association with the cortical membrane. Mol Biol cell 2006; 17: 4142-4155
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4142-4155
-
-
Dho, S.E.1
Trejo, J.2
Siderovski, D.P.3
McGlade, C.J.4
-
15
-
-
78649503266
-
Two novel human NUMB isoforms provide a potential link between development and cancer
-
Karaczyn A, Bani-Yaghoub M, Tremblay R, Kubu C, Cowling R, Adams TL et al. Two novel human NUMB isoforms provide a potential link between development and cancer. Neural Dev 2010; 5: 31
-
(2010)
Neural Dev
, vol.5
, pp. 31
-
-
Karaczyn, A.1
Bani-Yaghoub, M.2
Tremblay, R.3
Kubu, C.4
Cowling, R.5
Adams, T.L.6
-
16
-
-
0030250783
-
Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate
-
Verdi JM, Schmandt R, Bashirullah A, Jacob S, Salvino R, Craig CG et al. Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate. Curr Biol 1996; 6: 1134-1145
-
(1996)
Curr Biol
, vol.6
, pp. 1134-1145
-
-
Verdi, J.M.1
Schmandt, R.2
Bashirullah, A.3
Jacob, S.4
Salvino, R.5
Craig, C.G.6
-
17
-
-
0033621169
-
Distinct human NUMB isoforms regulate differentiation vs
-
Verdi JM, Bashirullah A, Goldhawk DE, Kubu CJ, Jamali M, Meakin SO et al. Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage. Proc Natl Acad Sci USA 1999; 96: 10472-10476
-
(1999)
Proliferation in the Neuronal Lineage. Proc Natl Acad Sci USA
, vol.96
, pp. 10472-10476
-
-
Verdi, J.M.1
Bashirullah, A.2
Goldhawk, D.E.3
Kubu, C.J.4
Jamali, M.5
Meakin, S.O.6
-
18
-
-
0032705611
-
Characterization of four mammalian Numb protein isoforms
-
Dho SE, French MB, Woods SA, McGlade CJ. Characterization of four mammalian Numb protein isoforms. J Biol Chem 1999; 274: 33097-33104
-
(1999)
J Biol Chem
, vol.274
, pp. 33097-33104
-
-
Dho, S.E.1
French, M.B.2
Woods, S.A.3
McGlade, C.J.4
-
19
-
-
84886492660
-
NumbL is essential for Xenopus primary neurogenesis
-
Nieber F, Hedderich M, Jahn O, Pieler T, Henningfeld KA. NumbL is essential for Xenopus primary neurogenesis. BMC Dev Biol 2013; 13: 36
-
(2013)
BMC Dev Biol
, vol.13
, pp. 36
-
-
Nieber, F.1
Hedderich, M.2
Jahn, O.3
Pieler, T.4
Henningfeld, K.A.5
-
20
-
-
33645470190
-
Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio
-
Reugels AM, Boggetti B, Scheer N, Campos-Ortega JA. Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio. Dev Dyn 2006; 235: 934-948
-
(2006)
Dev Dyn
, vol.235
, pp. 934-948
-
-
Reugels, A.M.1
Boggetti, B.2
Scheer, N.3
Campos-Ortega, J.A.4
-
21
-
-
77954365140
-
Alternative splicing is frequent during early embryonic development in mouse
-
Revil T, Gaffney D, Dias C, Majewski J, Jerome-Majewska LA. Alternative splicing is frequent during early embryonic development in mouse. BMC Genomics 2010; 11: 399
-
(2010)
BMC Genomics
, vol.11
, pp. 399
-
-
Revil, T.1
Gaffney, D.2
Dias, C.3
Majewski, J.4
Jerome-Majewska, L.A.5
-
22
-
-
0037413906
-
Involvement of numb in vertebrate retinal development: Evidence for multiple roles of numb in neural differentiation and maturation
-
Dooley CM, James J, McGlade CJ, Ahmad I. Involvement of numb in vertebrate retinal development: evidence for multiple roles of numb in neural differentiation and maturation. J Neurobiol 2003; 54: 313-325
-
(2003)
J Neurobiol
, vol.54
, pp. 313-325
-
-
Dooley, C.M.1
James, J.2
McGlade, C.J.3
Ahmad, I.4
-
23
-
-
0242360766
-
Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas
-
Yoshida T, Tokunaga A, Nakao K, Okano H. Distinct expression patterns of splicing isoforms of mNumb in the endocrine lineage of developing pancreas. Differentiation 2003; 71: 486-495
-
(2003)
Differentiation
, vol.71
, pp. 486-495
-
-
Yoshida, T.1
Tokunaga, A.2
Nakao, K.3
Okano, H.4
-
24
-
-
33947404377
-
A switch in numb isoforms is a critical step in cortical development
-
Bani-Yaghoub M, Kubu CJ, Cowling R, Rochira J, Nikopoulos GN, Bellum S et al. A switch in numb isoforms is a critical step in cortical development. Dev Dyn 2007; 236: 696-705
-
(2007)
Dev Dyn
, vol.236
, pp. 696-705
-
-
Bani-Yaghoub, M.1
Kubu, C.J.2
Cowling, R.3
Rochira, J.4
Nikopoulos, G.N.5
Bellum, S.6
-
25
-
-
33644635120
-
-
Toriya M, Tokunaga A, Sawamoto K, Nakao K, Okano H. Distinct functions of human numb isoforms revealed by misexpression in the neural stem cell lineage in the Drosophila larval brain. Dev Neurosci 2006; 28: 142-155
-
(2006)
Distinct Functions of Human Numb Isoforms Revealed by Misexpression in the Neural Stem Cell Lineage in the Drosophila Larval Brain. Dev Neurosci
, vol.28
, pp. 142-155
-
-
Toriya, M.1
Tokunaga, A.2
Sawamoto, K.3
Nakao, K.4
Okano, H.5
-
26
-
-
7244250027
-
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis
-
Pece S, Serresi M, Santolini E, Capra M, Hulleman E, Galimberti V et al. Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis. J Cell Biol 2004; 167: 215-221
-
(2004)
J Cell Biol
, vol.167
, pp. 215-221
-
-
Pece, S.1
Serresi, M.2
Santolini, E.3
Capra, M.4
Hulleman, E.5
Galimberti, V.6
-
27
-
-
32944470488
-
Aberrant activation of notch signaling in human breast cancer
-
Stylianou S, Clarke RB, Brennan K. Aberrant activation of notch signaling in human breast cancer. Cancer Res 2006; 66: 1517-1525
-
(2006)
Cancer Res
, vol.66
, pp. 1517-1525
-
-
Stylianou, S.1
Clarke, R.B.2
Brennan, K.3
-
28
-
-
76049110053
-
Alterations of the Notch pathway in lung cancer
-
Westhoff B, Colaluca IN, D'Ario G, Donzelli M, Tosoni D, Volorio S et al. Alterations of the Notch pathway in lung cancer. Proc Natl Acad Sci USA 2009; 106: 22293-22298
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 22293-22298
-
-
Westhoff, B.1
Colaluca, I.N.2
D'Ario, G.3
Donzelli, M.4
Tosoni, D.5
Volorio, S.6
-
29
-
-
84865201590
-
Therapeutic effect of -secretase inhibition in KrasG12Vdriven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK
-
Maraver A, Fernandez-Marcos PJ, Herranz D, Cañamero M, Muñoz-Martin M, Gómez-López G et al. Therapeutic effect of -secretase inhibition in KrasG12Vdriven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK. Cancer Cell 2012; 22: 222-234
-
(2012)
Cancer Cell
, vol.22
, pp. 222-234
-
-
Maraver, A.1
Fernandez-Marcos, P.J.2
Herranz, D.3
Cañamero, M.4
Muñoz-Martin, M.5
Gómez-López, G.6
-
30
-
-
84890192305
-
RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation
-
Bechara EG, Sebestyén E, Bernardis I, Eyras E, Valcárcel J. RBM5, 6, and 10 differentially regulate NUMB alternative splicing to control cancer cell proliferation. Mol Cell 2013; 52: 720-733
-
(2013)
Mol Cell
, vol.52
, pp. 720-733
-
-
Bechara, E.G.1
Sebestyén, E.2
Bernardis, I.3
Eyras, E.4
Valcárcel, J.5
-
31
-
-
78751700506
-
Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer
-
Misquitta-Ali CM, Cheng E, O'Hanlon D, Liu N, McGlade CJ, Tsao MS et al. Global profiling and molecular characterization of alternative splicing events misregulated in lung cancer. Mol Cell Biol 2011; 31: 138-150
-
(2011)
Mol Cell Biol
, vol.31
, pp. 138-150
-
-
Misquitta-Ali, C.M.1
Cheng, E.2
O'Hanlon, D.3
Liu, N.4
McGlade, C.J.5
Tsao, M.S.6
-
32
-
-
84901300422
-
The RNA-binding protein QK1 suppresses cancer-associated aberrant splicing
-
Zong F-Y, Fu X, Wei W-J, Luo Y-G, Heiner M, Cao L-J et al. The RNA-binding protein QK1 suppresses cancer-associated aberrant splicing. PLoS Genet 2014; 10: e1004289
-
(2014)
PLoS Genet
, vol.10
, pp. e1004289
-
-
Zong, F.-Y.1
Fu, X.2
Wei, W.-J.3
Luo, Y.-G.4
Heiner, M.5
Cao, L.-J.6
-
33
-
-
78649491922
-
Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer
-
Langer W, Sohler F, Leder G, Beckmann G, Seidel H, Gröne J et al. Exon array analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer. BMC Genomics 2010; 11: 676
-
(2010)
BMC Genomics
, vol.11
, pp. 676
-
-
Langer, W.1
Sohler, F.2
Leder, G.3
Beckmann, G.4
Seidel, H.5
Gröne, J.6
-
34
-
-
84897984333
-
Transcriptome profiling of a multiple recurrent muscle-invasive urothelial carcinoma of the bladder by deep sequencing
-
Zhang S, Liu Y, Liu Z, Zhang C, Cao H, Ye Y et al. Transcriptome profiling of a multiple recurrent muscle-invasive urothelial carcinoma of the bladder by deep sequencing. PLoS One 2014; 9: e91466
-
(2014)
PLoS One
, vol.9
, pp. e91466
-
-
Zhang, S.1
Liu, Y.2
Liu, Z.3
Zhang, C.4
Cao, H.5
Ye, Y.6
-
35
-
-
77954284248
-
SFmap: A web server for motif analysis and prediction of splicing factor binding sites
-
Paz I, Akerman M, Dror I, Kosti I, Mandel-Gutfreund Y. SFmap: A web server for motif analysis and prediction of splicing factor binding sites. Nucleic Acids Res 2010; 38: W281-W285
-
(2010)
Nucleic Acids Res
, vol.38
, pp. W281-W285
-
-
Paz, I.1
Akerman, M.2
Dror, I.3
Kosti, I.4
Mandel-Gutfreund, Y.5
-
36
-
-
0035898616
-
The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4
-
Stickeler E, Fraser SD, Honig A, Chen AL, Berget SM, Cooper TA. The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4. EMBO J 2001; 20: 3821-3830
-
(2001)
EMBO J
, vol.20
, pp. 3821-3830
-
-
Stickeler, E.1
Fraser, S.D.2
Honig, A.3
Chen, A.L.4
Berget, S.M.5
Cooper, T.A.6
-
37
-
-
84867900618
-
PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis
-
Izaguirre DI, Zhu W, Hai T, Cheung HC, Krahe R, Cote GJ. PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis. Mol Carcinog 2012; 51: 895-906
-
(2012)
Mol Carcinog
, vol.51
, pp. 895-906
-
-
Izaguirre, D.I.1
Zhu, W.2
Hai, T.3
Cheung, H.C.4
Krahe, R.5
Cote, G.J.6
-
38
-
-
40749163248
-
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
-
Christofk HR, Vander Heiden MG, Harris MH, Ramanathan A, Gerszten RE, Wei R et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature 2008; 452: 230-233
-
(2008)
Nature
, vol.452
, pp. 230-233
-
-
Christofk, H.R.1
Vander Heiden, M.G.2
Harris, M.H.3
Ramanathan, A.4
Gerszten, R.E.5
Wei, R.6
-
39
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R, de StanChina E, Lowe SW, Sinha R, Mu D, Krainer AR. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 2007; 14: 185-193
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
De StanChina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
40
-
-
57149097433
-
Structural insights into RNA recognition by the alternativesplicing regulator muscleblind-like MBNL1
-
Teplova M, Patel DJ. Structural insights into RNA recognition by the alternativesplicing regulator muscleblind-like MBNL1. Nat Struct Mol Biol 2008; 15: 1343-1351
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1343-1351
-
-
Teplova, M.1
Patel, D.J.2
-
41
-
-
4143120231
-
Muscleblind proteins regulate alternative splicing
-
Ho TH, Charlet BN, Poulos MG, Singh G, Swanson MS, Cooper TA. Muscleblind proteins regulate alternative splicing. EMBO J 2004; 23: 3103-3112
-
(2004)
EMBO J
, vol.23
, pp. 3103-3112
-
-
Ho, T.H.1
Charlet, B.N.2
Poulos, M.G.3
Singh, G.4
Swanson, M.S.5
Cooper, T.A.6
-
42
-
-
77954838957
-
Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls
-
Zhang C, Frias MA, Mele A, Ruggiu M, Eom T, Marney CB et al. Integrative modeling defines the Nova splicing-regulatory network and its combinatorial controls. Science 2010; 329: 439-443
-
(2010)
Science
, vol.329
, pp. 439-443
-
-
Zhang, C.1
Frias, M.A.2
Mele, A.3
Ruggiu, M.4
Eom, T.5
Marney, C.B.6
-
43
-
-
67749110060
-
Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines
-
Cheung HC, Hai T, Zhu W, Baggerly Ka, Tsavachidis S, Krahe R et al. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain 2009; 132: 2277-2288
-
(2009)
Brain
, vol.132
, pp. 2277-2288
-
-
Cheung, H.C.1
Hai, T.2
Zhu, W.3
Baggerly, Ka.4
Tsavachidis, S.5
Krahe, R.6
-
44
-
-
0035872199
-
Akt/Protein Kinase B is constitutively active in non-small cell lung cancer and promotes cellular survival and resistance to chemotherapy and radiation
-
Brognard J, Clark AS, Ni Y, Dennis PA. Akt/Protein Kinase B is constitutively active in non-small cell lung cancer and promotes cellular survival and resistance to chemotherapy and radiation. Cancer Res 2001; 61: 3986-3997
-
(2001)
Cancer Res
, vol.61
, pp. 3986-3997
-
-
Brognard, J.1
Clark, A.S.2
Ni, Y.3
Dennis, P.A.4
-
45
-
-
34248591612
-
Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer
-
Roberts PJ, Der CJ. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Oncogene 2007; 26: 3291-3310
-
(2007)
Oncogene
, vol.26
, pp. 3291-3310
-
-
Roberts, P.J.1
Der, C.J.2
-
46
-
-
24344453386
-
Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex
-
Ohori M, Kinoshita T, Okubo M, Sato K, Yamazaki A, Arakawa H et al. Identification of a selective ERK inhibitor and structural determination of the inhibitor-ERK2 complex. Biochem Biophys Res Commun 2005; 336: 357-363
-
(2005)
Biochem Biophys Res Commun
, vol.336
, pp. 357-363
-
-
Ohori, M.1
Kinoshita, T.2
Okubo, M.3
Sato, K.4
Yamazaki, A.5
Arakawa, H.6
-
47
-
-
84874395788
-
Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development
-
Kim KK, Nam J, Mukouyama Y-S, Kawamoto S. Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development. J Cell Biol 2013; 200: 443-458
-
(2013)
J Cell Biol
, vol.200
, pp. 443-458
-
-
Kim, K.K.1
Nam, J.2
Mukouyama, Y.-S.3
Kawamoto, S.4
-
48
-
-
34547212309
-
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
-
Makeyev EV, Zhang J, Carrasco MA, Maniatis T. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 2007; 27: 435-448
-
(2007)
Mol Cell
, vol.27
, pp. 435-448
-
-
Makeyev, E.V.1
Zhang, J.2
Carrasco, M.A.3
Maniatis, T.4
-
49
-
-
84903790972
-
Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties
-
He X, Arslan AD, Ho T-T, Yuan C, Stampfer MR, Beck WT. Involvement of polypyrimidine tract-binding protein (PTBP1) in maintaining breast cancer cell growth and malignant properties. Oncogenesis 2014; 3: e84
-
(2014)
Oncogenesis
, vol.3
, pp. e84
-
-
He, X.1
Arslan, A.D.2
Ho, T.-T.3
Yuan, C.4
Stampfer, M.R.5
Beck, W.T.6
-
50
-
-
34547489950
-
Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro
-
He X, Pool M, Darcy KM, Lim SB, Auersperg N, Coon JS et al. Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro. Oncogene 2007; 26: 4961-4968
-
(2007)
Oncogene
, vol.26
, pp. 4961-4968
-
-
He, X.1
Pool, M.2
Darcy, K.M.3
Lim, S.B.4
Auersperg, N.5
Coon, J.S.6
-
51
-
-
0942266266
-
Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain
-
McCutcheon IE, Hentschel SJ, Fuller GN, Jin W, Cote GJ. Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain. Neuro-Oncology 2004; 6: 9-14
-
(2004)
Neuro-Oncology
, vol.6
, pp. 9-14
-
-
McCutcheon, I.E.1
Hentschel, S.J.2
Fuller, G.N.3
Jin, W.4
Cote, G.J.5
-
52
-
-
33746322370
-
Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma
-
Cheung HC, Corley LJ, Fuller GN, McCutcheon IE, Cote GJ. Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol 2006; 19: 1034-1041
-
(2006)
Mod Pathol
, vol.19
, pp. 1034-1041
-
-
Cheung, H.C.1
Corley, L.J.2
Fuller, G.N.3
McCutcheon, I.E.4
Cote, G.J.5
-
53
-
-
84861131874
-
Oncogenic splicing factor SRSF1 is a critical transcriptional target of MYC
-
Das S, Anczuków O, Akerman M, Krainer AR. Oncogenic splicing factor SRSF1 is a critical transcriptional target of MYC. Cell Rep 2012; 1: 110-117
-
(2012)
Cell Rep
, vol.1
, pp. 110-117
-
-
Das, S.1
Anczuków, O.2
Akerman, M.3
Krainer, A.R.4
-
54
-
-
84876929370
-
HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells
-
Guo R, Li Y, Ning J, Sun D, Lin L, Liu X. HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells. PLoS One 2013; 8: e62729
-
(2013)
PLoS One
, vol.8
, pp. e62729
-
-
Guo, R.1
Li, Y.2
Ning, J.3
Sun, D.4
Lin, L.5
Liu, X.6
-
55
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray SJ. Notch signalling: A simple pathway becomes complex. Nat Rev Mol Cell Biol 2006; 7: 678-689
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
56
-
-
78951481235
-
Role of Notch and its oncogenic signaling crosstalk in breast cancer
-
Guo S, Liu M, Gonzalez-Perez R. Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta 2011; 1815: 197-213
-
(2011)
Biochim Biophys Acta
, vol.1815
, pp. 197-213
-
-
Guo, S.1
Liu, M.2
Gonzalez-Perez, R.3
-
58
-
-
84873161936
-
High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF? Pathways as fundamental Notch regulators in breast cancer
-
Izrailit J, Berman HK, Datti A, Wrana JL, Reedijk M. High throughput kinase inhibitor screens reveal TRB3 and MAPK-ERK/TGF? pathways as fundamental Notch regulators in breast cancer. Proc Natl Acad Sci USA 2013; 110: 1714-1719
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1714-1719
-
-
Izrailit, J.1
Berman, H.K.2
Datti, A.3
Wrana, J.L.4
Reedijk, M.5
-
59
-
-
77953298449
-
Nuclear RNA export and packaging functions of HIV-1 Rev revisited
-
Blissenbach M, Grewe B, Hoffmann B, Brandt S, Uberla K. Nuclear RNA export and packaging functions of HIV-1 Rev revisited. J Virol 2010; 84: 6598-6604
-
(2010)
J Virol
, vol.84
, pp. 6598-6604
-
-
Blissenbach, M.1
Grewe, B.2
Hoffmann, B.3
Brandt, S.4
Uberla, K.5
-
60
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
|