-
1
-
-
84872662082
-
-
CBTRUS. Volume 2009.: Central Brain Tumor Registry of the United States
-
CBTRUS. Volume 2009. http://www.cbtrus.org/: Central Brain Tumor Registry of the United States; 2009.
-
(2009)
-
-
-
2
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research N.
-
Cancer Genome Atlas Research N. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
-
3
-
-
77952555038
-
Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma
-
Van Meir EG, Hadjipanayis CG, Norden AD, Shu HK, Wen PY, Olson JJ. Exciting new advances in neuro-oncology: The avenue to a cure for malignant glioma. CA Cancer J Clin 2010; 60: 166-193.
-
(2010)
CA Cancer J Clin
, vol.60
, pp. 166-193
-
-
Van Meir, E.G.1
Hadjipanayis, C.G.2
Norden, A.D.3
Shu, H.K.4
Wen, P.Y.5
Olson, J.J.6
-
4
-
-
56749098074
-
Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing
-
Pan Q, Shai O, Lee LJ, Frey BJ, Blencowe BJ. Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing. Nat Genet 2008; 40: 1413-1415.
-
(2008)
Nat Genet
, vol.40
, pp. 1413-1415
-
-
Pan, Q.1
Shai, O.2
Lee, L.J.3
Frey, B.J.4
Blencowe, B.J.5
-
5
-
-
56549101959
-
Alternative isoform regulation in human tissue transcriptomes
-
Wang ET, Sandberg R, Luo S, et al. Alternative isoform regulation in human tissue transcriptomes. Nature 2008; 456: 470-476.
-
(2008)
Nature
, vol.456
, pp. 470-476
-
-
Wang, E.T.1
Sandberg, R.2
Luo, S.3
-
6
-
-
33746927884
-
The connection between splicing and cancer
-
Srebrow A, Kornblihtt AR. The connection between splicing and cancer. J Cell Sci 2006; 119: 2635-2641.
-
(2006)
J Cell Sci
, vol.119
, pp. 2635-2641
-
-
Srebrow, A.1
Kornblihtt, A.R.2
-
7
-
-
14644437799
-
Splicing factors are differentially expressed in tumors
-
Kirschbaum-Slager N, Lopes GM, Galante PA, Riggins GJ, de Souza SJ. Splicing factors are differentially expressed in tumors. Genet Mol Res 2004; 3: 512-520.
-
(2004)
Genet Mol Res
, vol.3
, pp. 512-520
-
-
Kirschbaum-Slager, N.1
Lopes, G.M.2
Galante, P.A.3
Riggins, G.J.4
de Souza, S.J.5
-
8
-
-
44649126097
-
Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays
-
Cheung H, Baggerly K, Tsavachidis S, et al. Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays. BMC Genomics 2008; 9: 216.
-
(2008)
BMC Genomics
, vol.9
, pp. 216
-
-
Cheung, H.1
Baggerly, K.2
Tsavachidis, S.3
-
9
-
-
73149083495
-
Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase
-
Gao Y, Fotovati A, Lee C, et al. Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase. Mol Cancer Ther 2009; 8: 3276-3284.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3276-3284
-
-
Gao, Y.1
Fotovati, A.2
Lee, C.3
-
10
-
-
55549143293
-
The emerging role of splicing factors in cancer
-
Grosso AR, Martins S, Carmo-Fonseca M. The emerging role of splicing factors in cancer. EMBO Rep 2008; 9: 1087-1093.
-
(2008)
EMBO Rep
, vol.9
, pp. 1087-1093
-
-
Grosso, A.R.1
Martins, S.2
Carmo-Fonseca, M.3
-
11
-
-
7444220147
-
Aberrant and alternative splicing in cancer
-
Venables JP. Aberrant and alternative splicing in cancer. Cancer Res 2004; 64: 7647-7654.
-
(2004)
Cancer Res
, vol.64
, pp. 7647-7654
-
-
Venables, J.P.1
-
12
-
-
21244439380
-
Regulation of apoptosis by alternative pre-mRNA splicing
-
Schwerk C, Schulze-Osthoff K. Regulation of apoptosis by alternative pre-mRNA splicing. Mol Cell 2005; 19: 1-13.
-
(2005)
Mol Cell
, vol.19
, pp. 1-13
-
-
Schwerk, C.1
Schulze-Osthoff, K.2
-
13
-
-
78751647679
-
Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer
-
He X, Arslan AD, Pool MD, et al. Knockdown of splicing factor SRp20 causes apoptosis in ovarian cancer cells and its expression is associated with malignancy of epithelial ovarian cancer. Oncogene 2010; 30: 356-365.
-
(2010)
Oncogene
, vol.30
, pp. 356-365
-
-
He, X.1
Arslan, A.D.2
Pool, M.D.3
-
14
-
-
34547489950
-
Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro
-
He X, Pool M, Darcy KM, et al. Knockdown of polypyrimidine tract-binding protein suppresses ovarian tumor cell growth and invasiveness in vitro. Oncogene 2007; 26: 4961-4968.
-
(2007)
Oncogene
, vol.26
, pp. 4961-4968
-
-
He, X.1
Pool, M.2
Darcy, K.M.3
-
15
-
-
33847630730
-
The gene encoding the splicing factor SF2/ASF is a proto-oncogene
-
Karni R, de Stanchina E, Lowe SW, Sinha R, Mu D, Krainer AR. The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol 2007; 14: 185-193.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 185-193
-
-
Karni, R.1
de Stanchina, E.2
Lowe, S.W.3
Sinha, R.4
Mu, D.5
Krainer, A.R.6
-
16
-
-
77956923246
-
Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors
-
Zhu R, Heaney J, Nadeau JH, Ali S, Matin A. Deficiency of splicing factor 1 suppresses the occurrence of testicular germ cell tumors. Cancer Res 2010; 70: 7264-7272.
-
(2010)
Cancer Res
, vol.70
, pp. 7264-7272
-
-
Zhu, R.1
Heaney, J.2
Nadeau, J.H.3
Ali, S.4
Matin, A.5
-
17
-
-
50649091392
-
Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner
-
Wang C, Norton JT, Ghosh S, et al. Polypyrimidine tract-binding protein (PTB) differentially affects malignancy in a cell line-dependent manner. J Biol Chem 2008; 283: 20277-20287.
-
(2008)
J Biol Chem
, vol.283
, pp. 20277-20287
-
-
Wang, C.1
Norton, J.T.2
Ghosh, S.3
-
18
-
-
33746322370
-
Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma
-
Cheung HC, Corley LJ, Fuller GN, McCutcheon IE, Cote GJ. Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol 2006; 19: 1034-1041.
-
(2006)
Mod Pathol
, vol.19
, pp. 1034-1041
-
-
Cheung, H.C.1
Corley, L.J.2
Fuller, G.N.3
McCutcheon, I.E.4
Cote, G.J.5
-
19
-
-
67749110060
-
Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines
-
Cheung HC, Hai T, Zhu W, et al. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain 2009; 132: 2277-2288.
-
(2009)
Brain
, vol.132
, pp. 2277-2288
-
-
Cheung, H.C.1
Hai, T.2
Zhu, W.3
-
20
-
-
76649102764
-
The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism
-
Clower CV, Chatterjee D, Wang Z, Cantley LC, Vander Heiden MG, Krainer AR. The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proc Natl Acad Sci USA 2010; 107: 1894-1899.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1894-1899
-
-
Clower, C.V.1
Chatterjee, D.2
Wang, Z.3
Cantley, L.C.4
Vander Heiden, M.G.5
Krainer, A.R.6
-
21
-
-
75149150660
-
HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer
-
David CJ, Chen M, Assanah M, Canoll P, Manley JL. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature 2010; 463: 364-368.
-
(2010)
Nature
, vol.463
, pp. 364-368
-
-
David, C.J.1
Chen, M.2
Assanah, M.3
Canoll, P.4
Manley, J.L.5
-
22
-
-
0033990048
-
Primer3 on the WWW for general users and for biologist programmers
-
Rozen S, Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol 2000; 132: 365-386.
-
(2000)
Methods Mol Biol
, vol.132
, pp. 365-386
-
-
Rozen, S.1
Skaletsky, H.2
-
23
-
-
0034163539
-
Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors
-
Jin W, McCutcheon IE, Fuller GN, Huang ES, Cote GJ. Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors. Cancer Res 2000; 60: 1221-1224.
-
(2000)
Cancer Res
, vol.60
, pp. 1221-1224
-
-
Jin, W.1
McCutcheon, I.E.2
Fuller, G.N.3
Huang, E.S.4
Cote, G.J.5
-
24
-
-
0032938851
-
Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon
-
Lou H, Helfman DM, Gagel RF, Berget SM. Polypyrimidine tract-binding protein positively regulates inclusion of an alternative 3'-terminal exon. Mol Cell Biol 1999; 19: 78-85.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 78-85
-
-
Lou, H.1
Helfman, D.M.2
Gagel, R.F.3
Berget, S.M.4
-
25
-
-
19544363571
-
Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements
-
Bruno IG, Jin W, Cote GJ. Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet 2004; 13: 2409-2420.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2409-2420
-
-
Bruno, I.G.1
Jin, W.2
Cote, G.J.3
-
26
-
-
73249131626
-
Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
-
Reid DC, Chang BL, Gunderson SI, Alpert L, Thompson WA, Fairbrother WG. Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence. RNA 2009; 15: 2385-2397.
-
(2009)
RNA
, vol.15
, pp. 2385-2397
-
-
Reid, D.C.1
Chang, B.L.2
Gunderson, S.I.3
Alpert, L.4
Thompson, W.A.5
Fairbrother, W.G.6
-
27
-
-
0024842159
-
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns
-
García-Blanco MA, Jamison SF, Sharp PA. Identification and purification of a 62, 000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev 1989; 3: 1874-1886.
-
(1989)
Genes Dev
, vol.3
, pp. 1874-1886
-
-
García-Blanco, M.A.1
Jamison, S.F.2
Sharp, P.A.3
-
28
-
-
34547205013
-
Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1
-
Spellman R, Llorian M, Smith CWJ. Crossregulation and functional redundancy between the splicing regulator PTB and its paralogs nPTB and ROD1. Mol Cell 2007; 27: 420-434.
-
(2007)
Mol Cell
, vol.27
, pp. 420-434
-
-
Spellman, R.1
Llorian, M.2
Smith, C.W.J.3
-
29
-
-
0035038207
-
Polypyrimidine tract binding protein antagonizes exon definition
-
Wagner EJ, Garcia-Blanco MA. Polypyrimidine tract binding protein antagonizes exon definition. Mol Cell Biol 2001; 21: 3281-3288.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 3281-3288
-
-
Wagner, E.J.1
Garcia-Blanco, M.A.2
-
30
-
-
0032055106
-
Determination of functional domains in polypyrimidine-tract binding protein
-
Oh YL, Hahm B, Kim YK, et al. Determination of functional domains in polypyrimidine-tract binding protein. Biochem J 1998; 331: 169-175.
-
(1998)
Biochem J
, vol.331
, pp. 169-175
-
-
Oh, Y.L.1
Hahm, B.2
Kim, Y.K.3
-
31
-
-
49349112872
-
Polypyrimidine-tract binding protein: A multifunctional RNA-binding protein
-
Sawicka K, Bushell M, Spriggs KA, Willis AE. Polypyrimidine-tract binding protein: A multifunctional RNA-binding protein. Biochem Soc Trans 2008; 36: 641-647.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 641-647
-
-
Sawicka, K.1
Bushell, M.2
Spriggs, K.A.3
Willis, A.E.4
-
32
-
-
77956342570
-
Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB
-
Llorian M, Schwartz S, Clark TA, et al. Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB. Nat Struct Mol Biol 2010; 17: 1114-1123.
-
(2010)
Nat Struct Mol Biol
, vol.17
, pp. 1114-1123
-
-
Llorian, M.1
Schwartz, S.2
Clark, T.A.3
-
33
-
-
34347384211
-
A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
-
Boutz PL, Stoilov P, Li Q, et al. A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev 2007; 21: 1636-1652.
-
(2007)
Genes Dev
, vol.21
, pp. 1636-1652
-
-
Boutz, P.L.1
Stoilov, P.2
Li, Q.3
-
34
-
-
48149096726
-
MADS: A new and improved method for analysis of differential alternative splicing by exon-tiling microarrays
-
Xing Y, Stoilov P, Kapur K, et al. MADS: A new and improved method for analysis of differential alternative splicing by exon-tiling microarrays. RNA 2008; 14: 1470-1479.
-
(2008)
RNA
, vol.14
, pp. 1470-1479
-
-
Xing, Y.1
Stoilov, P.2
Kapur, K.3
-
35
-
-
34547212309
-
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
-
Makeyev EV, Zhang J, Carrasco MA, Maniatis T. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell 2007; 27: 435-448.
-
(2007)
Mol Cell
, vol.27
, pp. 435-448
-
-
Makeyev, E.V.1
Zhang, J.2
Carrasco, M.A.3
Maniatis, T.4
-
36
-
-
34250795169
-
Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays
-
French PJ, Peeters J, Horsman S, et al. Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays. Cancer Res 2007; 67: 5635-5642.
-
(2007)
Cancer Res
, vol.67
, pp. 5635-5642
-
-
French, P.J.1
Peeters, J.2
Horsman, S.3
-
37
-
-
0028823598
-
Metabolism of the polyubiquitin degradation signal: Structure, mechanism, and role of isopeptidase T
-
Wilkinson KD, Tashayev VL, O'Connor LB, Larsen CN, Kasperek E, Pickart CM. Metabolism of the polyubiquitin degradation signal: Structure, mechanism, and role of isopeptidase T. Biochemistry 1995; 34: 14535-14546.
-
(1995)
Biochemistry
, vol.34
, pp. 14535-14546
-
-
Wilkinson, K.D.1
Tashayev, V.L.2
O'Connor, L.B.3
Larsen, C.N.4
Kasperek, E.5
Pickart, C.M.6
-
38
-
-
0029943614
-
A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13
-
Ansari-Lari MA, Muzny DM, Lu J, et al. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. Genome Res 1996; 6: 314-326.
-
(1996)
Genome Res
, vol.6
, pp. 314-326
-
-
Ansari-Lari, M.A.1
Muzny, D.M.2
Lu, J.3
-
39
-
-
12344250822
-
Function of alternative splicing
-
Stamm S, Ben-Ari S, Rafalska I, et al. Function of alternative splicing. Gene 2005; 344: 1-20.
-
(2005)
Gene
, vol.344
, pp. 1-20
-
-
Stamm, S.1
Ben-Ari, S.2
Rafalska, I.3
-
40
-
-
72149117411
-
Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping
-
Xue Y, Zhou Y, Wu T, et al. Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Mol Cell 2009; 36: 996-1006.
-
(2009)
Mol Cell
, vol.36
, pp. 996-1006
-
-
Xue, Y.1
Zhou, Y.2
Wu, T.3
-
41
-
-
33646765735
-
Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes
-
Mense SM, Sengupta A, Zhou M, et al. Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes. Physiol Genomics 2006; 25: 435-449.
-
(2006)
Physiol Genomics
, vol.25
, pp. 435-449
-
-
Mense, S.M.1
Sengupta, A.2
Zhou, M.3
-
42
-
-
18144417086
-
Abnormal regulation of RNA splicing in gliomas
-
In: Zhang W, Fuller GN, editors
-
Cote GJ, Bruno IG, Jin W. Abnormal regulation of RNA splicing in gliomas. In: Zhang W, Fuller GN, editors. Genomic and molecular neuro-oncology. Sudbury: Jones and Bartlett Publishers, Inc. 2003. pp. 165-183.
-
(2003)
Genomic and molecular neuro-oncology. Sudbury: Jones and Bartlett Publishers, Inc
, pp. 165-183
-
-
Cote, G.J.1
Bruno, I.G.2
Jin, W.3
-
43
-
-
0942266266
-
Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain
-
McCutcheon IE Hentschel SJ Fuller GN Jin W Cote GJ Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain Neuro Oncol 2004; 6: 9-14.
-
(2004)
Neuro Oncol
, vol.6
, pp. 9-14
-
-
McCutcheon, I.E.1
Hentschel, S.J.2
Fuller, G.N.3
Jin, W.4
Cote, G.J.5
-
44
-
-
50349102579
-
Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T
-
Reyes-Turcu FE, Shanks JR, Komander D, Wilkinson KD. Recognition of polyubiquitin isoforms by the multiple ubiquitin binding modules of isopeptidase T. J Biol Chem 2008; 283: 19581-19592.
-
(2008)
J Biol Chem
, vol.283
, pp. 19581-19592
-
-
Reyes-Turcu, F.E.1
Shanks, J.R.2
Komander, D.3
Wilkinson, K.D.4
-
45
-
-
84867897514
-
-
Sciences EL. Isopeptidase T [UBP5] long form (human, recombinant) product data sheet. Volume 2010;.
-
Sciences EL. Isopeptidase T [UBP5] long form (human, recombinant) product data sheet. Volume 2010; 2009.
-
(2009)
-
-
-
46
-
-
78549247880
-
Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis
-
Kapuria V, Peterson LF, Fang D, Bornmann WG, Talpaz M, Donato NJ. Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. Cancer Res 2010; 70: 9265-9276.
-
(2010)
Cancer Res
, vol.70
, pp. 9265-9276
-
-
Kapuria, V.1
Peterson, L.F.2
Fang, D.3
Bornmann, W.G.4
Talpaz, M.5
Donato, N.J.6
-
47
-
-
64149087218
-
Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53
-
Dayal S, Sparks A, Jacob J, Allende-Vega N, Lane DP, Saville MK. Suppression of the deubiquitinating enzyme USP5 causes the accumulation of unanchored polyubiquitin and the activation of p53. J Biol Chem 2009; 284: 5030-5041.
-
(2009)
J Biol Chem
, vol.284
, pp. 5030-5041
-
-
Dayal, S.1
Sparks, A.2
Jacob, J.3
Allende-Vega, N.4
Lane, D.P.5
Saville, M.K.6
|