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Volumn 34, Issue 4, 2015, Pages 346-348

Systems Toxicology: The Future of Risk Assessment

Author keywords

risk assessment; systems toxicology

Indexed keywords

ARTICLE; CLINICAL RESEARCH; COMPUTER MODEL; RISK ASSESSMENT; RISK MANAGEMENT; SYSTEMS TOXICOLOGY; TOXICOLOGY; ANIMAL; DANGEROUS GOODS; DISEASE MODEL; ENVIRONMENTAL EXPOSURE; HUMAN; ORGANIZATION; TOXICITY;

EID: 84937496036     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581815576551     Document Type: Article
Times cited : (31)

References (16)
  • 1
    • 84860798653 scopus 로고    scopus 로고
    • Systems toxicology
    • 2012
    • Hartung T, van Vliet E, Jaworska J,. 2012. Systems toxicology. ALTEX. 2012; 29 (2): 119-128.
    • (2012) ALTEX , vol.29 , Issue.2 , pp. 119-128
    • Hartung, T.1    Van Vliet, E.2    Jaworska, J.3
  • 2
    • 84896366331 scopus 로고    scopus 로고
    • Systems toxicology: From basic research to risk assessment
    • Sturla SJ, Boobis AR, FitzGerald RE,. Systems toxicology: from basic research to risk assessment. Chem Res Toxicol. 2014; 27 (3): 314-329.
    • (2014) Chem Res Toxicol , vol.27 , Issue.3 , pp. 314-329
    • Sturla, S.J.1    Boobis, A.R.2    FitzGerald, R.E.3
  • 3
    • 22044435932 scopus 로고    scopus 로고
    • Guidance on good cell culture practice
    • Coecke S, Balls M, Bowe G,. Guidance on good cell culture practice. Altern Lab Anim. 2005; 33 (3): 261-287.
    • (2005) Altern Lab Anim , vol.33 , Issue.3 , pp. 261-287
    • Coecke, S.1    Balls, M.2    Bowe, G.3
  • 4
    • 84864582983 scopus 로고    scopus 로고
    • Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare
    • Hartung T, Zurlo J,. Alternative approaches for medical countermeasures to biological and chemical terrorism and warfare. ALTEX. 2012; 29 (3): 251-260.
    • (2012) ALTEX , vol.29 , Issue.3 , pp. 251-260
    • Hartung, T.1    Zurlo, J.2
  • 5
    • 84904901205 scopus 로고    scopus 로고
    • Developing microphysiological systems for use as regulatory tools - Challenges and opportunities
    • 2014
    • Andersen M, Betts K, Dragan Y,. 2014. Developing microphysiological systems for use as regulatory tools-challenges and opportunities. ALTEX. 2014; 31 (3): 364-367.
    • (2014) ALTEX , vol.31 , Issue.3 , pp. 364-367
    • Andersen, M.1    Betts, K.2    Dragan, Y.3
  • 7
    • 84883880887 scopus 로고    scopus 로고
    • Look back in anger - What clinical studies tell us about preclinical work
    • Hartung T,. Look back in anger-what clinical studies tell us about preclinical work. ALTEX. 2013; 30 (3): 275-291.
    • (2013) ALTEX , vol.30 , Issue.3 , pp. 275-291
    • Hartung, T.1
  • 8
    • 84876323285 scopus 로고    scopus 로고
    • Integrated testing strategies for safety assessments
    • 2013
    • Hartung T, Luechtefeld T, Maertens A, Kleensang A., 2013. Integrated testing strategies for safety assessments. ALTEX. 2013; 30 (1): 3-18.
    • (2013) ALTEX , vol.30 , Issue.1 , pp. 3-18
    • Hartung, T.1    Luechtefeld, T.2    Maertens, A.3    Kleensang, A.4
  • 9
    • 84901008801 scopus 로고    scopus 로고
    • Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+)
    • Krug AK, Gutbier S, Zhao L,. Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP(+). Cell Death Dis. 2014; 5: e1222.
    • (2014) Cell Death Dis , vol.5 , pp. e1222
    • Krug, A.K.1    Gutbier, S.2    Zhao, L.3
  • 10
    • 84876922933 scopus 로고    scopus 로고
    • A computational model predicting disruption of blood vessel development
    • doi:10.1371/journal.pcbi.1002996
    • Kleinstreuer N, Dix D, Rountree M,. A computational model predicting disruption of blood vessel development. PLoS Comput Biol. 2013; 9 (4): e1002996. doi:10.1371/journal.pcbi.1002996.
    • (2013) PLoS Comput Biol , vol.9 , Issue.4 , pp. e1002996
    • Kleinstreuer, N.1    Dix, D.2    Rountree, M.3
  • 11
    • 84860698978 scopus 로고    scopus 로고
    • A network-based approach to quantify the impact of biologically active substances
    • Hoeng J, Deehan R, Pratt D,. A network-based approach to quantify the impact of biologically active substances. Drug Discov Today. 2012; 17 (9-10): 413-418.
    • (2012) Drug Discov Today , vol.17 , Issue.9-10 , pp. 413-418
    • Hoeng, J.1    Deehan, R.2    Pratt, D.3
  • 12
    • 84898889450 scopus 로고    scopus 로고
    • A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes
    • Kogel U, Schlage WK, Martin F,. A 28-day rat inhalation study with an integrated molecular toxicology endpoint demonstrates reduced exposure effects for a prototypic modified risk tobacco product compared with conventional cigarettes. Food Chem Toxicol. 2014; 68: 204-217.
    • (2014) Food Chem Toxicol , vol.68 , pp. 204-217
    • Kogel, U.1    Schlage, W.K.2    Martin, F.3
  • 13
    • 84904074764 scopus 로고    scopus 로고
    • Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models
    • Martin F, Sewer A, Talikka M, Xiang Y, Hoeng J, Peitsch MC,. Quantification of biological network perturbations for mechanistic insight and diagnostics using two-layer causal models. BMC Bioinformatics, 2014; 15: 238.
    • (2014) BMC Bioinformatics , vol.15 , pp. 238
    • Martin, F.1    Sewer, A.2    Talikka, M.3    Xiang, Y.4    Hoeng, J.5    Peitsch, M.C.6
  • 14
    • 84878227954 scopus 로고    scopus 로고
    • Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers
    • Mathis C, Poussin C, Weisensee D,. Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers. Am J Physiol Lung Cell Mol Physiol. 2013; 304 (7): L489-L503.
    • (2013) Am J Physiol Lung Cell Mol Physiol , vol.304 , Issue.7 , pp. L489-L503
    • Mathis, C.1    Poussin, C.2    Weisensee, D.3
  • 15
    • 84886571799 scopus 로고    scopus 로고
    • Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues
    • Iskandar AR, Martin F, Talikka M,. Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues. Biomed Res Int. 2013; 2013: 512086.
    • (2013) Biomed Res Int , vol.2013 , pp. 512086
    • Iskandar, A.R.1    Martin, F.2    Talikka, M.3
  • 16
    • 84895918030 scopus 로고    scopus 로고
    • Case study: The role of mechanistic network models in systems toxicology
    • Hoeng J, Talikka M, Martin F,. Case study: the role of mechanistic network models in systems toxicology. Drug Discov Today. 2014; 19 (2): 183-192.
    • (2014) Drug Discov Today , vol.19 , Issue.2 , pp. 183-192
    • Hoeng, J.1    Talikka, M.2    Martin, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.