Highlight report: Towards the replacement of in vivo repeated dose systemic toxicity testing

Archives of Toxicology

Volumn 86, Issue 1, 2012, Pages 13-15

  Hengstler, Jan G ^a   Marchan, Rosemarie ^a   Leist, Marcel ^b  

^a TU DORTMUND UNIVERSITY   (Germany)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 NONYLPHENOL; ACETYLSALICYLIC ACID; ALCOHOL; ALPIDEM; BROMFENAC; CAFFEINE; CARBAMAZEPINE; CARBON TETRACHLORIDE; DEXAMETHASONE; DICLOFENAC; FLUTAMIDE; IBUPROFEN; IMIPRAMINE; INDUSTRIAL CHEMICAL; LOSARTAN; METHYLMERCURY; NEFAZODONE; PARACETAMOL; PAROXETINE; PERFLUOROOCTANESULFONIC ACID; PIOGLITAZONE; ROSIGLITAZONE; SERTRALINE; TACRINE; THEOPHYLLINE; TICLOPIDINE; TIENILIC ACID; TROGLITAZONE; UNINDEXED DRUG; VENLAFAXINE;

ALCOHOL LIVER CIRRHOSIS; CONCENTRATION RESPONSE; DRUG EXPOSURE; EDITORIAL; FATTY LIVER; HUMAN; HYPERTENSION; IMMUNOTOXICITY; IN VIVO STUDY; LIVER FIBROSIS; LIVER TOXICITY; NONHUMAN; OXIDATIVE STRESS; PREDICTION; PRIORITY JOURNAL; TOXIC HEPATITIS; TOXICITY TESTING; TOXICOKINETICS; VASOCONSTRICTION;

CARBON TETRACHLORIDE; DRUG ADMINISTRATION SCHEDULE; DRUG-INDUCED LIVER INJURY; EUROPEAN UNION; HUMANS; NO-OBSERVED-ADVERSE-EFFECT LEVEL; PHARMACEUTICAL PREPARATIONS; TOXICITY TESTS;

EID: 84856967407     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0798-7     Document Type: Editorial

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