A non-inheritable maternal Cas9-based multiple-gene editing system in mice

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Sakurai, Takayuki ^a   Kamiyoshi, Akiko ^a   Kawate, Hisaka ^a   Mori, Chie ^a   Watanabe, Satoshi ^b   Tanaka, Megumu ^a   Uetake, Ryuichi ^a   Sato, Masahiro ^c   Shindo, Takayuki ^a  

^a SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^c KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; FEMALE; FERTILIZATION IN VITRO; GENE OVEREXPRESSION; GENOME; MATING; MICROINJECTION; MOUSE; NONHUMAN; SPERM; TRANSGENIC MOUSE; ZYGOTE; ANIMAL; CRISPR CAS SYSTEM; FIBROBLAST; GENE EDITING; GENE EXPRESSION; GENE LOCUS; GENETICS; INDEL MUTATION; LIVER CELL; MALE; METABOLISM; MUTATION; OOCYTE; PHENOTYPE; SPERMATOZOON; TRANSGENE;

CRISPR ASSOCIATED PROTEIN; GALACTOSYLTRANSFERASE; GUIDE RNA;

ANIMALS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; FEMALE; FIBROBLASTS; GALACTOSYLTRANSFERASES; GENE EDITING; GENE EXPRESSION; GENETIC LOCI; GENOME; HEPATOCYTES; INDEL MUTATION; MALE; MICE; MICE, TRANSGENIC; MUTATION; OOCYTES; PHENOTYPE; RNA, GUIDE; SPERMATOZOA; TRANSGENES; ZYGOTE;

EID: 84961387095     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20011     Document Type: Article

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