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Volumn 27, Issue 5, 2016, Pages 393-401

Platelet-derived sphingosine-1-phosphate and inflammation: from basic mechanisms to clinical implications

Author keywords

Inflammation; platelets; sphingosine 1 phosphate

Indexed keywords

SPHINGOSINE 1 PHOSPHATE; ANTIINFLAMMATORY AGENT; LYSOPHOSPHOLIPID; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE;

EID: 84961215971     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2016.1144179     Document Type: Review
Times cited : (24)

References (138)
  • 1
    • 84880010050 scopus 로고    scopus 로고
    • The incredible journey: From megakaryocyte development to platelet formation
    • K.R.Machlus, I.J.E.JrItaliano JE. The incredible journey: From megakaryocyte development to platelet formation. J Cell Biol 2013;201:785–796.
    • (2013) J Cell Biol , vol.201 , pp. 785-796
    • Machlus, K.R.1    Jr, I.J.E.2
  • 2
    • 84929319009 scopus 로고    scopus 로고
    • Platelet secretion: From haemostasis to wound healing and beyond
    • E.M.Golebiewska, A.W.Poole Platelet secretion: From haemostasis to wound healing and beyond. Blood Rev 2015;29:153–162.
    • (2015) Blood Rev , vol.29 , pp. 153-162
    • Golebiewska, E.M.1    Poole, A.W.2
  • 3
    • 84887001106 scopus 로고    scopus 로고
    • Differentiating haemostasis from thrombosis for therapeutic benefit
    • J.D.McFadyen, S.P.Jackson Differentiating haemostasis from thrombosis for therapeutic benefit. Thromb Haemos 2013;110:859–867.
    • (2013) Thromb Haemos , vol.110 , pp. 859-867
    • McFadyen, J.D.1    Jackson, S.P.2
  • 4
    • 51349119099 scopus 로고    scopus 로고
    • Platelet adhesion: A game of catch and release
    • R.K.Andrews, M.C.Berndt Platelet adhesion: A game of catch and release. J Clin Invest 2008;118:3009–3011.
    • (2008) J Clin Invest , vol.118 , pp. 3009-3011
    • Andrews, R.K.1    Berndt, M.C.2
  • 7
  • 9
    • 84926614405 scopus 로고    scopus 로고
    • Platelets in inflammation: Regulation of leukocyte activities and vascular repair
    • A.Gros, V.Ollivier, B.Ho-Tin-Noé Platelets in inflammation: Regulation of leukocyte activities and vascular repair. Front Immunol 2015;5:678.
    • (2015) Front Immunol , vol.5 , pp. 678
    • Gros, A.1    Ollivier, V.2    Ho-Tin-Noé, B.3
  • 10
    • 84929299635 scopus 로고    scopus 로고
    • Platelets in inflammation and infection
    • C.N.Jenne, P.Kubes Platelets in inflammation and infection. Platelets 2015;26:286–292.
    • (2015) Platelets , vol.26 , pp. 286-292
    • Jenne, C.N.1    Kubes, P.2
  • 11
    • 46949090337 scopus 로고    scopus 로고
    • Platelet-lymphocyte cross-talk
    • N.Li Platelet-lymphocyte cross-talk. J Leukoc Biol 2008;83:1069–1078.
    • (2008) J Leukoc Biol , vol.83 , pp. 1069-1078
    • Li, N.1
  • 12
    • 84888326067 scopus 로고    scopus 로고
    • The uncoupling of monocyte-platelet interactions from the induction of proinflammatory signaling in monocytes
    • J.Stephen, B.Emerson, K.A.Fox, I.Dransfield The uncoupling of monocyte-platelet interactions from the induction of proinflammatory signaling in monocytes. J Immunol 2013;191:5677–5683.
    • (2013) J Immunol , vol.191 , pp. 5677-5683
    • Stephen, J.1    Emerson, B.2    Fox, K.A.3    Dransfield, I.4
  • 13
    • 78149315850 scopus 로고    scopus 로고
    • Macrophage pro-inflammatory cytokine secretion is enhanced following interaction with autologous platelets
    • C.M.Scull, W.D.Hays, T.H.Fischer Macrophage pro-inflammatory cytokine secretion is enhanced following interaction with autologous platelets. J Inflamm (Lond) 2010;7:53.
    • (2010) J Inflamm (Lond) , vol.7 , pp. 53
    • Scull, C.M.1    Hays, W.D.2    Fischer, T.H.3
  • 15
    • 56949095716 scopus 로고    scopus 로고
    • Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease
    • S.Pyne, S.C.Lee, J.Long, N.J.Pyne Role of sphingosine kinases and lipid phosphate phosphatases in regulating spatial sphingosine 1-phosphate signalling in health and disease. Cell Signal 2009;21:14–21.
    • (2009) Cell Signal , vol.21 , pp. 14-21
    • Pyne, S.1    Lee, S.C.2    Long, J.3    Pyne, N.J.4
  • 16
    • 84857901223 scopus 로고    scopus 로고
    • Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells
    • X.Liu, Q.H.Zhang, G.H.Yi Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells. Mol Cell Biochem 2012;363:21–33.
    • (2012) Mol Cell Biochem , vol.363 , pp. 21-33
    • Liu, X.1    Zhang, Q.H.2    Yi, G.H.3
  • 17
    • 0037518448 scopus 로고    scopus 로고
    • Salvage pathways in glycosphingolipid metabolism
    • G.Tettamanti, R.Bassi, P.Viani, L.Riboni Salvage pathways in glycosphingolipid metabolism. Biochimie 2003;85:423–437.
    • (2003) Biochimie , vol.85 , pp. 423-437
    • Tettamanti, G.1    Bassi, R.2    Viani, P.3    Riboni, L.4
  • 18
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling: Lessons from sphingolipids
    • Y.A.Hannun, L.M.Obeid Principles of bioactive lipid signalling: Lessons from sphingolipids. Nature Rev Mol Cell Biol 2008;9:139–150.
    • (2008) Nature Rev Mol Cell Biol , vol.9 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 19
    • 46949104885 scopus 로고    scopus 로고
    • Inside-out” signaling of sphingosine-1-phosphate: Therapeutic targets
    • K.Takabe, S.W.Paugh, S.Milstien, S.Spiegel “Inside-out” signaling of sphingosine-1-phosphate: Therapeutic targets. Pharmacol Rev 2008;60:181–195.
    • (2008) Pharmacol Rev , vol.60 , pp. 181-195
    • Takabe, K.1    Paugh, S.W.2    Milstien, S.3    Spiegel, S.4
  • 22
    • 84897954582 scopus 로고    scopus 로고
    • Molecular and physiological functions of sphingosine 1-phosphate transporters
    • T.Nishi, N.Kobayashi, Y.Hisano, Y.A.Kawahara Atsuo, Yamaguchi A. Molecular and physiological functions of sphingosine 1-phosphate transporters. Biochim Biophys Acta 2014;1841:759–765.
    • (2014) Biochim Biophys Acta , vol.1841 , pp. 759-765
    • Nishi, T.1    Kobayashi, N.2    Hisano, Y.3    Kawahara Atsuo, Y.A.4
  • 24
    • 84905003546 scopus 로고    scopus 로고
    • An update on the biology of sphingosine 1-phosphate receptors
    • V.A.Blaho, T.Hla An update on the biology of sphingosine 1-phosphate receptors. J Lipid Res 2014;55:1596–1608.
    • (2014) J Lipid Res , vol.55 , pp. 1596-1608
    • Blaho, V.A.1    Hla, T.2
  • 25
    • 84926293921 scopus 로고    scopus 로고
    • Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy
    • R.L.Proia, T.Hla Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. J Clin Invest 2015;125:1379–1387.
    • (2015) J Clin Invest , vol.125 , pp. 1379-1387
    • Proia, R.L.1    Hla, T.2
  • 26
    • 77953771709 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function
    • M.Serra, J.D.Saba Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function. Adv Enzyme Regul 2010;50:349–362.
    • (2010) Adv Enzyme Regul , vol.50 , pp. 349-362
    • Serra, M.1    Saba, J.D.2
  • 28
    • 84937237383 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases and their roles in mammalian physiology and pathology
    • X.Tang, M.G.K.Benesch, D.N.Brindley Lipid phosphate phosphatases and their roles in mammalian physiology and pathology. J Lipid Res 2015;56:2048–2060.
    • (2015) J Lipid Res , vol.56 , pp. 2048-2060
    • Tang, X.1    Benesch, M.G.K.2    Brindley, D.N.3
  • 29
    • 84937112643 scopus 로고    scopus 로고
    • metabolism, and regulation of circulating sphingosine-1-phosphate
    • M.Książek, M.Chacińska, A.Chabowski, B.M.SourcesBaranowski M., metabolism, and regulation of circulating sphingosine-1-phosphate. J Lipid Res 2015;56:1271–1281.
    • (2015) J Lipid Res , vol.56 , pp. 1271-1281
    • Książek, M.1    Chacińska, M.2    Chabowski, A.3    Sources, B.M.4
  • 31
    • 0034672133 scopus 로고    scopus 로고
    • Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions
    • N.Murata, K.Sato, J.Kon, H.Tomura, M.Yanagita, A.Kuwabara, M.Ui, F.Okajima Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions. Biochem J 2000;352:809–815.
    • (2000) Biochem J , vol.352 , pp. 809-815
    • Murata, N.1    Sato, K.2    Kon, J.3    Tomura, H.4    Yanagita, M.5    Kuwabara, A.6    Ui, M.7    Okajima, F.8
  • 32
    • 0037162038 scopus 로고    scopus 로고
    • Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?
    • F.Okajima Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator? Biochim Biophys Acta 2002;1582:132–137.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 132-137
    • Okajima, F.1
  • 33
    • 0030961305 scopus 로고    scopus 로고
    • 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum
    • Y.Yatomi, Y.Igarashi, L.Yang, N.Hisano, R.Qi, N.Asazuma, K.Satoh, Y.Ozaki, K.S.SphingosineKume S. 1-phosphate, a bioactive sphingolipid abundantly stored in platelets, is a normal constituent of human plasma and serum. J Biochem 1997;121:969–973.
    • (1997) J Biochem , vol.121 , pp. 969-973
    • Yatomi, Y.1    Igarashi, Y.2    Yang, L.3    Hisano, N.4    Qi, R.5    Asazuma, N.6    Satoh, K.7    Ozaki, Y.8    Sphingosine, K.S.9
  • 34
    • 33947634013 scopus 로고    scopus 로고
    • Erythrocytes store and release sphingosine 1-phosphate in blood
    • P.Hänel, P.Andreani, M.H.Graler Erythrocytes store and release sphingosine 1-phosphate in blood. FASEB J 2007;21:1202–1209.
    • (2007) FASEB J , vol.21 , pp. 1202-1209
    • Hänel, P.1    Andreani, P.2    Graler, M.H.3
  • 37
    • 0032734494 scopus 로고    scopus 로고
    • Metabolism and functional effects of sphingolipids in blood cells
    • L.Yang, Y.Yatomi, Y.Miura, K.Satoh, Y.Ozaki Metabolism and functional effects of sphingolipids in blood cells. Br J Haematol 1999;107:282–293.
    • (1999) Br J Haematol , vol.107 , pp. 282-293
    • Yang, L.1    Yatomi, Y.2    Miura, Y.3    Satoh, K.4    Ozaki, Y.5
  • 40
    • 84862188843 scopus 로고    scopus 로고
    • Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells
    • Y.Hisano, N.Kobayashi, A.Yamaguchi, T.Nishi Mouse SPNS2 functions as a sphingosine-1-phosphate transporter in vascular endothelial cells. PLoS One 2012;7:e38941.
    • (2012) PLoS One , vol.7 , Issue.e38941
    • Hisano, Y.1    Kobayashi, N.2    Yamaguchi, A.3    Nishi, T.4
  • 45
    • 84904017360 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate as a link between blood coagulation and inflammation
    • B.H.Rauch Sphingosine 1-phosphate as a link between blood coagulation and inflammation. Cell Physiol Biochem 2014;34:185–196.
    • (2014) Cell Physiol Biochem , vol.34 , pp. 185-196
    • Rauch, B.H.1
  • 46
    • 84859701240 scopus 로고    scopus 로고
    • 1-phosphate in coagulation and inflammation
    • H.Obinata, H.T.SphingosineHla T. 1-phosphate in coagulation and inflammation. Semin Immunopathol 2012;34:73–91.
    • (2012) Semin Immunopathol , vol.34 , pp. 73-91
    • Obinata, H.1    Sphingosine, H.T.2
  • 47
    • 0029052921 scopus 로고
    • Sphingosine-1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets
    • Y.Yatomi, F.Ruan, S.Hakomori, Y.Igarashi Sphingosine-1-phosphate: A platelet-activating sphingolipid released from agonist-stimulated human platelets. Blood 1995;86:193–202.
    • (1995) Blood , vol.86 , pp. 193-202
    • Yatomi, Y.1    Ruan, F.2    Hakomori, S.3    Igarashi, Y.4
  • 48
    • 64949189983 scopus 로고    scopus 로고
    • The S1P(2) receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes
    • V.Randriamboavonjy, K.Badenhoop, H.Schmidt, G.Geisslinger, B.Fisslthaler, I.Fleming The S1P(2) receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes. Basic Res Cardiol 2009;104:333–340.
    • (2009) Basic Res Cardiol , vol.104 , pp. 333-340
    • Randriamboavonjy, V.1    Badenhoop, K.2    Schmidt, H.3    Geisslinger, G.4    Fisslthaler, B.5    Fleming, I.6
  • 49
    • 0035052260 scopus 로고    scopus 로고
    • Phospholipids released from activated platelets improve platelet aggregation and endothelial cell migration
    • H.Xiao, R.A.Siddiqui, M.H.Al-Hassani, D.Sliva, R.J.Kovacs Phospholipids released from activated platelets improve platelet aggregation and endothelial cell migration. Platelets 2001;12:163–170.
    • (2001) Platelets , vol.12 , pp. 163-170
    • Xiao, H.1    Siddiqui, R.A.2    Al-Hassani, M.H.3    Sliva, D.4    Kovacs, R.J.5
  • 51
    • 0033926364 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate: Characterization of its inhibition of platelet aggregation
    • D.Nugent, Y.Xu Sphingosine-1-phosphate: Characterization of its inhibition of platelet aggregation. Platelets 2000;11:226–232.
    • (2000) Platelets , vol.11 , pp. 226-232
    • Nugent, D.1    Xu, Y.2
  • 53
    • 0031040704 scopus 로고    scopus 로고
    • 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid
    • Y.Yatomi, S.Yamamura, F.Ruan, I.Y.SphingosineIgarashi Y. 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. J Biol Chem 1997;272:5291–5297.
    • (1997) J Biol Chem , vol.272 , pp. 5291-5297
    • Yatomi, Y.1    Yamamura, S.2    Ruan, F.3    Sphingosine, I.Y.4
  • 55
    • 27444446836 scopus 로고    scopus 로고
    • Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets
    • M.Tani, T.Sano, M.Ito, Y.Igarashi Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. J Lipid Res 2005;46:2458–2467.
    • (2005) J Lipid Res , vol.46 , pp. 2458-2467
    • Tani, M.1    Sano, T.2    Ito, M.3    Igarashi, Y.4
  • 56
    • 0014448632 scopus 로고
    • Lipid composition of subcellular particles of human blood platelets
    • A.J.Marcus, H.L.Ullman, L.B.Safier Lipid composition of subcellular particles of human blood platelets. J Lipid Res 1969;10:108–114.
    • (1969) J Lipid Res , vol.10 , pp. 108-114
    • Marcus, A.J.1    Ullman, H.L.2    Safier, L.B.3
  • 57
    • 0032868934 scopus 로고    scopus 로고
    • Secretory sphingomyelinase
    • I.Tabas Secretory sphingomyelinase. Chem Phys Lipids 1999;102:123–130.
    • (1999) Chem Phys Lipids , vol.102 , pp. 123-130
    • Tabas, I.1
  • 58
    • 0029666484 scopus 로고    scopus 로고
    • 2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene
    • 2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene. J Biol Chem 1996;271:18431–18436.
    • (1996) J Biol Chem , vol.271 , pp. 18431-18436
    • Schissel, S.L.1    Schuchman, E.H.2    Williams, K.J.3    Tabas, I.4
  • 63
    • 0032524380 scopus 로고    scopus 로고
    • Sphingomyelinase activity in human platelets
    • S.C.G.JrSimon CG, S.Chatterjee, A.R.Gear Sphingomyelinase activity in human platelets. Thromb Res 1998;90:155–161.
    • (1998) Thromb Res , vol.90 , pp. 155-161
    • Jr, S.C.G.1    Chatterjee, S.2    Gear, A.R.3
  • 64
    • 0041734874 scopus 로고    scopus 로고
    • Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1
    • Y.Fukuda, A.Kihara, Y.Igarashi Distribution of sphingosine kinase activity in mouse tissues: contribution of SPHK1. Biochem Biophys Res Commun 2003;309:155–160.
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 155-160
    • Fukuda, Y.1    Kihara, A.2    Igarashi, Y.3
  • 65
    • 0032532629 scopus 로고    scopus 로고
    • Evidence for the presence of multiple forms of Sph kinase in human platelets
    • Y.Banno, M.Kato, A.Hara, Y.Nozawa Evidence for the presence of multiple forms of Sph kinase in human platelets. Biochem J 1998;335:301–304.
    • (1998) Biochem J , vol.335 , pp. 301-304
    • Banno, Y.1    Kato, M.2    Hara, A.3    Nozawa, Y.4
  • 68
    • 0242290332 scopus 로고    scopus 로고
    • Lipid phosphate phosphatases regulate lysophosphatidic acid production and signalling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity
    • S.S.Smyth, V.A.Sciorra, Y.J.Sigal, Z.Pamuklar, Z.Wang, Y.Xu, G.D.Prestwich, A.J.Morris Lipid phosphate phosphatases regulate lysophosphatidic acid production and signalling in platelets: studies using chemical inhibitors of lipid phosphate phosphatase activity. J Biol Chem 2003;278:43214–43223.
    • (2003) J Biol Chem , vol.278 , pp. 43214-43223
    • Smyth, S.S.1    Sciorra, V.A.2    Sigal, Y.J.3    Pamuklar, Z.4    Wang, Z.5    Xu, Y.6    Prestwich, G.D.7    Morris, A.J.8
  • 69
    • 84873938350 scopus 로고    scopus 로고
    • 1-phosphate release from platelets during clot formation: Close correlation between platelet count and serum sphingosine 1-phosphate concentration
    • Y.Ono, M.Kurano, R.Ohkawa, H.Yokota, K.Igarashi, J.Aoki, M.Tozuka, Y.Y.SphingosineYatomi Y. 1-phosphate release from platelets during clot formation: Close correlation between platelet count and serum sphingosine 1-phosphate concentration. Lipids Health Dis 2013;12:20–26.
    • (2013) Lipids Health Dis , vol.12 , pp. 20-26
    • Ono, Y.1    Kurano, M.2    Ohkawa, R.3    Yokota, H.4    Igarashi, K.5    Aoki, J.6    Tozuka, M.7    Sphingosine, Y.Y.8
  • 71
    • 0037077199 scopus 로고    scopus 로고
    • Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood
    • T.Sano, D.Baker, T.Virag, A.Wada, Y.Yatomi, T.Kobayashi, Y.Igarashi, G.Tigyi Multiple mechanisms linked to platelet activation result in lysophosphatidic acid and sphingosine 1-phosphate generation in blood. J Biol Chem 2002;277:21197–21206.
    • (2002) J Biol Chem , vol.277 , pp. 21197-21206
    • Sano, T.1    Baker, D.2    Virag, T.3    Wada, A.4    Yatomi, Y.5    Kobayashi, T.6    Igarashi, Y.7    Tigyi, G.8
  • 72
    • 34250891906 scopus 로고    scopus 로고
    • The immunomodulator FTY720 is phosphorylated and released from platelets
    • Y.Anada, Y.Igarashi, A.Kihara The immunomodulator FTY720 is phosphorylated and released from platelets. Eur J Pharmacol 2007;568:106–111.
    • (2007) Eur J Pharmacol , vol.568 , pp. 106-111
    • Anada, Y.1    Igarashi, Y.2    Kihara, A.3
  • 73
    • 84941695034 scopus 로고    scopus 로고
    • Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation
    • C.Frej, A.Andersson, B.Larsson, L.J.Guo, E.Norström, K.E.Happonen, B.Dahlbäck Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation. Anal Bioanal Chem 2015;407:8533–8542.
    • (2015) Anal Bioanal Chem , vol.407 , pp. 8533-8542
    • Frej, C.1    Andersson, A.2    Larsson, B.3    Guo, L.J.4    Norström, E.5    Happonen, K.E.6    Dahlbäck, B.7
  • 75
    • 84871747576 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: High density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1
    • B.A.Wilkerson, G.D.Grass, S.B.Wing, W.S.Argraves, K.M.Argraves Sphingosine 1-phosphate (S1P) carrier-dependent regulation of endothelial barrier: High density lipoprotein (HDL)-S1P prolongs endothelial barrier enhancement as compared with albumin-S1P via effects on levels, trafficking, and signaling of S1P1. J Biol Chem 2012;287:44645–44653.
    • (2012) J Biol Chem , vol.287 , pp. 44645-44653
    • Wilkerson, B.A.1    Grass, G.D.2    Wing, S.B.3    Argraves, W.S.4    Argraves, K.M.5
  • 76
    • 84901936622 scopus 로고    scopus 로고
    • Sphingolipid metabolites in inflammatory disease
    • M.Maceyka, S.Spiegel Sphingolipid metabolites in inflammatory disease. Nature 2014;510:58–67.
    • (2014) Nature , vol.510 , pp. 58-67
    • Maceyka, M.1    Spiegel, S.2
  • 78
    • 0032524380 scopus 로고    scopus 로고
    • Gear AR Sphingomyelinase activity in human platelets
    • S.C.G.JrSimon CG, S.Chatterjee, Gear AR Sphingomyelinase activity in human platelets. Thromb Res 1998;90:155–161.
    • (1998) Thromb Res , vol.90 , pp. 155-161
    • Jr, S.C.G.1    Chatterjee, S.2
  • 79
    • 12944316607 scopus 로고    scopus 로고
    • Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis
    • M.L.Wong, B.Xie, N.Beatini, P.Phu, S.Marathe, A.Johns, P.W.Gold, E.Hirsch, K.J.Williams, J.Licinio, et al. Acute systemic inflammation up-regulates secretory sphingomyelinase in vivo: a possible link between inflammatory cytokines and atherogenesis. Proc Natl Acad Sci USA 2000;97:8681–8686.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8681-8686
    • Wong, M.L.1    Xie, B.2    Beatini, N.3    Phu, P.4    Marathe, S.5    Johns, A.6    Gold, P.W.7    Hirsch, E.8    Williams, K.J.9    Licinio, J.10
  • 80
    • 84943617743 scopus 로고    scopus 로고
    • Secretory sphingomyelinase in health and disease
    • J.Kornhuber, C.Rhein, C.P.Müller, C.Mühle Secretory sphingomyelinase in health and disease. Biol Chem 2015;396:707–736.
    • (2015) Biol Chem , vol.396 , pp. 707-736
    • Kornhuber, J.1    Rhein, C.2    Müller, C.P.3    Mühle, C.4
  • 83
    • 84877044874 scopus 로고    scopus 로고
    • Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets
    • W.-F.Chen, J.-J.Lee, C.-C.Chang, K.-H.Lin, H.Wang, J.-R.Sheu Platelet protease-activated receptor (PAR)4, but not PAR1, associated with neutral sphingomyelinase responsible for thrombin-stimulated ceramide-NF-κB signaling in human platelets. Haematol 2013;98:793–801.
    • (2013) Haematol , vol.98 , pp. 793-801
    • Chen, W.-F.1    Lee, J.-J.2    Chang, C.-C.3    Lin, K.-H.4    Wang, H.5    Sheu, J.-R.6
  • 85
    • 0037162037 scopus 로고    scopus 로고
    • Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
    • M.J.Kluk, T.Hla Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors. Biochim Biophys Acta 2002;1582:72–80.
    • (2002) Biochim Biophys Acta , vol.1582 , pp. 72-80
    • Kluk, M.J.1    Hla, T.2
  • 87
    • 77952946424 scopus 로고    scopus 로고
    • Endothelial functions of sphingosine-1-phosphate
    • S.Lucke, B.Levkau Endothelial functions of sphingosine-1-phosphate. Cell Physiol Biochem 2010;26:87–96.
    • (2010) Cell Physiol Biochem , vol.26 , pp. 87-96
    • Lucke, S.1    Levkau, B.2
  • 88
    • 0034670042 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells
    • Y.Yatomi, T.Ohmori, G.Rile, F.Kazama, H.Okamoto, T.Sano, K.Satoh, S.Kume, G.Tigyi, Y.Igarashi, et al. Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells. Blood 2000;96:3431–3438.
    • (2000) Blood , vol.96 , pp. 3431-3438
    • Yatomi, Y.1    Ohmori, T.2    Rile, G.3    Kazama, F.4    Okamoto, H.5    Sano, T.6    Satoh, K.7    Kume, S.8    Tigyi, G.9    Igarashi, Y.10
  • 89
    • 84904250638 scopus 로고    scopus 로고
    • S1P control of endothelial integrity
    • Y.Xiong, T.Hla S1P control of endothelial integrity. Curr Top Microbiol Immunol 2014;378:85–105.
    • (2014) Curr Top Microbiol Immunol , vol.378 , pp. 85-105
    • Xiong, Y.1    Hla, T.2
  • 92
    • 0035895735 scopus 로고    scopus 로고
    • Platelet-released phospholipids link haemostasis and angiogenesis
    • D.English, J.G.Garcia, D.N.Brindley Platelet-released phospholipids link haemostasis and angiogenesis. Cardiovasc Res 2001;49:588–599.
    • (2001) Cardiovasc Res , vol.49 , pp. 588-599
    • English, D.1    Garcia, J.G.2    Brindley, D.N.3
  • 93
    • 84925933664 scopus 로고    scopus 로고
    • The functional role of platelets in the regulation of angiogenesis
    • T.G.Walsh, P.Metharom, M.C.Berndt The functional role of platelets in the regulation of angiogenesis. Platelets 2015;26:199–211.
    • (2015) Platelets , vol.26 , pp. 199-211
    • Walsh, T.G.1    Metharom, P.2    Berndt, M.C.3
  • 95
    • 33847644058 scopus 로고    scopus 로고
    • 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3
    • C.I.Lin, C.N.Chen, P.W.Lin, L.H.SphingosineLee H. 1-phosphate regulates inflammation-related genes in human endothelial cells through S1P1 and S1P3. Biochem Biophys Res Commun 2007;355:895–901.
    • (2007) Biochem Biophys Res Commun , vol.355 , pp. 895-901
    • Lin, C.I.1    Chen, C.N.2    Lin, P.W.3    Sphingosine, L.H.4
  • 97
    • 70149099834 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate enhances Fc gamma receptor-mediated neutrophil activation and recruitment under flow conditions
    • O.Florey, D.O.Haskard Sphingosine 1-phosphate enhances Fc gamma receptor-mediated neutrophil activation and recruitment under flow conditions. J Immunol 2009;183:2330–2336.
    • (2009) J Immunol , vol.183 , pp. 2330-2336
    • Florey, O.1    Haskard, D.O.2
  • 98
    • 84907495523 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes
    • S.Mahajan-Thakur, B.D.Sostmann, A.C.Fender, D.Behrendt, S.B.Felix, K.Schrör, B.H.Rauch Sphingosine-1-phosphate induces thrombin receptor PAR-4 expression to enhance cell migration and COX-2 formation in human monocytes. J Leukoc Biol 2014;96:611–618.
    • (2014) J Leukoc Biol , vol.96 , pp. 611-618
    • Mahajan-Thakur, S.1    Sostmann, B.D.2    Fender, A.C.3    Behrendt, D.4    Felix, S.B.5    Schrör, K.6    Rauch, B.H.7
  • 101
    • 70349562965 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate: A regulator of arterial lesions
    • G.Daum, A.Grabski, M.A.Reidy Sphingosine 1-phosphate: A regulator of arterial lesions. Arterioscler Thromb Vasc Biol 2009;29:1439–1443.
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 1439-1443
    • Daum, G.1    Grabski, A.2    Reidy, M.A.3
  • 102
    • 84905560895 scopus 로고    scopus 로고
    • Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P)
    • F.Potì, M.Simoni, J.R.Nofer Atheroprotective role of high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P). Cardiovasc Res 2014;103:395–404.
    • (2014) Cardiovasc Res , vol.103 , pp. 395-404
    • Potì, F.1    Simoni, M.2    Nofer, J.R.3
  • 103
    • 1242328678 scopus 로고    scopus 로고
    • Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells
    • K.Shimamura, Y.Takashiro, N.Akiyama, T.Hirabayashi, T.Murayama Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. Eur J Pharmacol 2004;486:141–150.
    • (2004) Eur J Pharmacol , vol.486 , pp. 141-150
    • Shimamura, K.1    Takashiro, Y.2    Akiyama, N.3    Hirabayashi, T.4    Murayama, T.5
  • 107
    • 46049118194 scopus 로고    scopus 로고
    • Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: Role in development of hypercholesterolemic atherosclerosis
    • D.J.Son, H.W.Lee, H.W.Shin, J.J.Lee, H.S.Yoo, T.J.Kim, Y.P.Yun, J.T.Hong Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: Role in development of hypercholesterolemic atherosclerosis. Prostaglandins Leukot Essent Fatty Acids 2008;78:383–390.
    • (2008) Prostaglandins Leukot Essent Fatty Acids , vol.78 , pp. 383-390
    • Son, D.J.1    Lee, H.W.2    Shin, H.W.3    Lee, J.J.4    Yoo, H.S.5    Kim, T.J.6    Yun, Y.P.7    Hong, J.T.8
  • 109
    • 0034016870 scopus 로고    scopus 로고
    • 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart
    • A.Sugiyama, Y.Yatomi, Y.Ozaki, H.K.SphingosineHashimoto K. 1-phosphate induces sinus tachycardia and coronary vasoconstriction in the canine heart. Cardiovasc Res 2000;46:119–125.
    • (2000) Cardiovasc Res , vol.46 , pp. 119-125
    • Sugiyama, A.1    Yatomi, Y.2    Ozaki, Y.3    Sphingosine, H.K.4
  • 110
    • 4444263184 scopus 로고    scopus 로고
    • Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2
    • T.Ohmori, Y.Yatomi, M.Osada, Y.Ozaki Platelet-derived sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. J Thromb Haemost 2004;2:203–205.
    • (2004) J Thromb Haemost , vol.2 , pp. 203-205
    • Ohmori, T.1    Yatomi, Y.2    Osada, M.3    Ozaki, Y.4
  • 111
    • 33846688688 scopus 로고    scopus 로고
    • FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice
    • J.R.Nofer, M.Bot, M.Brodde, P.J.Taylor, P.Salm, V.Brinkmann, T.van Berkel, G.Assmann, E.A.Biessen FTY720, a synthetic sphingosine 1 phosphate analogue, inhibits development of atherosclerosis in low-density lipoprotein receptor-deficient mice. Circulation 2007;115:501–508.
    • (2007) Circulation , vol.115 , pp. 501-508
    • Nofer, J.R.1    Bot, M.2    Brodde, M.3    Taylor, P.J.4    Salm, P.5    Brinkmann, V.6    van Berkel, T.7    Assmann, G.8    Biessen, E.A.9
  • 113
    • 33847348491 scopus 로고    scopus 로고
    • Systemic sclerosis: a prototypic multisystem fibrotic disorder
    • J.Varga, D.Abraham Systemic sclerosis: a prototypic multisystem fibrotic disorder. J Clin Invest 2007;117:557–567.
    • (2007) J Clin Invest , vol.117 , pp. 557-567
    • Varga, J.1    Abraham, D.2
  • 115
    • 84655175061 scopus 로고    scopus 로고
    • Understanding fibrosis in systemic sclerosis: Shifting paradigms, emerging opportunities
    • S.Bhattacharyya, J.Wei, J.Varga Understanding fibrosis in systemic sclerosis: Shifting paradigms, emerging opportunities. Nat Rev Rheumatol 2011;8:42–54.
    • (2011) Nat Rev Rheumatol , vol.8 , pp. 42-54
    • Bhattacharyya, S.1    Wei, J.2    Varga, J.3
  • 116
  • 117
    • 34948844518 scopus 로고    scopus 로고
    • Platelet contributions to the pathogenesis of systemic sclerosis
    • A.E.Postlethwaite, T.M.Chiang Platelet contributions to the pathogenesis of systemic sclerosis. Curr Opin Rheumatol 2007;19:574–579.
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 574-579
    • Postlethwaite, A.E.1    Chiang, T.M.2
  • 119
    • 79953661423 scopus 로고    scopus 로고
    • A role for lysophosphatidic acid and sphingosine 1-phosphate in the pathogenesis of systemic sclerosis
    • D.Pattanaik, A.E.Postlethwaite A role for lysophosphatidic acid and sphingosine 1-phosphate in the pathogenesis of systemic sclerosis. Discov Med 2010;10:161–167.
    • (2010) Discov Med , vol.10 , pp. 161-167
    • Pattanaik, D.1    Postlethwaite, A.E.2
  • 121
    • 80155139387 scopus 로고    scopus 로고
    • Vascular involvement in systemic sclerosis (scleroderma)
    • D.Pattanaik, M.Brown, A.E.Postlethwaite Vascular involvement in systemic sclerosis (scleroderma). J Inflam Res 2011;4:105–125.
    • (2011) J Inflam Res , vol.4 , pp. 105-125
    • Pattanaik, D.1    Brown, M.2    Postlethwaite, A.E.3
  • 122
    • 77954230505 scopus 로고    scopus 로고
    • 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels
    • S.Bu, Y.Asano, A.Bujor, K.Highland, F.Hant, T.M.DihydrosphingosineTrojanowska M. 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels. Arthritis Rheum 2010;62:2117–2126.
    • (2010) Arthritis Rheum , vol.62 , pp. 2117-2126
    • Bu, S.1    Asano, Y.2    Bujor, A.3    Highland, K.4    Hant, F.5    Dihydrosphingosine, T.M.6
  • 123
    • 0031974878 scopus 로고    scopus 로고
    • Pathogenesis of glomerular damage in glomerulonephritis
    • W.G.Couser Pathogenesis of glomerular damage in glomerulonephritis. Nephrol Dial Transplant 1998;13:10–15.
    • (1998) Nephrol Dial Transplant , vol.13 , pp. 10-15
    • Couser, W.G.1
  • 124
    • 0030727803 scopus 로고    scopus 로고
    • Platelets in glomerular disease
    • J.L.Barnes Platelets in glomerular disease. Nephron 1997;77:378–393.
    • (1997) Nephron , vol.77 , pp. 378-393
    • Barnes, J.L.1
  • 125
    • 0026538075 scopus 로고
    • Platelet-derived growth factor: a potentially important cytokine in glomerular disease
    • R.Johnson, H.Iida, A.Yoshimura, J.Floege, D.F.Bowen-Pope Platelet-derived growth factor: a potentially important cytokine in glomerular disease. Kidney Int 1992;41:590–594.
    • (1992) Kidney Int , vol.41 , pp. 590-594
    • Johnson, R.1    Iida, H.2    Yoshimura, A.3    Floege, J.4    Bowen-Pope, D.F.5
  • 128
    • 84890792936 scopus 로고    scopus 로고
    • Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases
    • S.Schwalm, J.Pfeilschifter, A.Huwiler Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. Basic Clin Pharmacol Toxicol 2014;114:44–49.
    • (2014) Basic Clin Pharmacol Toxicol , vol.114 , pp. 44-49
    • Schwalm, S.1    Pfeilschifter, J.2    Huwiler, A.3
  • 129
    • 0025174379 scopus 로고
    • Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat
    • R.J.Johnson, R.L.Garcia, P.Pritzl, C.E.Alpers Platelets mediate glomerular cell proliferation in immune complex nephritis induced by anti-mesangial cell antibodies in the rat. Am J Pathol 1990;136:369–374.
    • (1990) Am J Pathol , vol.136 , pp. 369-374
    • Johnson, R.J.1    Garcia, R.L.2    Pritzl, P.3    Alpers, C.E.4
  • 132
    • 36849020940 scopus 로고    scopus 로고
    • Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells
    • M.Osada, Y.Yatomi, T.Ohmori, S.Aoki, S.Hosogaya, Y.Ozaki Involvement of sphingosine 1-phosphate, a platelet-derived bioactive lipid, in contraction of mesangium cells. J Biochem 2007;142:351–355.
    • (2007) J Biochem , vol.142 , pp. 351-355
    • Osada, M.1    Yatomi, Y.2    Ohmori, T.3    Aoki, S.4    Hosogaya, S.5    Ozaki, Y.6
  • 134
    • 0031430418 scopus 로고    scopus 로고
    • A role for P-selectin in neutrophil and platelet infiltration in immune complex glomerulonephritis
    • C.R.Zachem, C.E.Alpers, W.Way, S.J.Shankland, W.G.Couser, R.J.Johnson A role for P-selectin in neutrophil and platelet infiltration in immune complex glomerulonephritis. J Am Soc Nephrol 1997;8:1838–1844.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 1838-1844
    • Zachem, C.R.1    Alpers, C.E.2    Way, W.3    Shankland, S.J.4    Couser, W.G.5    Johnson, R.J.6
  • 135
    • 0030054341 scopus 로고    scopus 로고
    • N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets
    • Y.Yatomi, F.Ruan, T.Megidish, T.Toyokuni, S.Hakomori, Y.Igarashi N,N-dimethylsphingosine inhibition of sphingosine kinase and sphingosine 1-phosphate activity in human platelets. Biochemistry 1996;35:626–633.
    • (1996) Biochemistry , vol.35 , pp. 626-633
    • Yatomi, Y.1    Ruan, F.2    Megidish, T.3    Toyokuni, T.4    Hakomori, S.5    Igarashi, Y.6
  • 136
    • 1842582861 scopus 로고    scopus 로고
    • Sphingolipids as bioactive regulators of thrombin generation
    • H.Deguchi, S.Yegneswaran, J.H.Griffin Sphingolipids as bioactive regulators of thrombin generation. J Biol Chem 2004;279:12036–12042.
    • (2004) J Biol Chem , vol.279 , pp. 12036-12042
    • Deguchi, H.1    Yegneswaran, S.2    Griffin, J.H.3


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