Conformational changes of apoB-100 in SMase-modified LDL mediate formation of large aggregates at acidic pH

Journal of Lipid Research

Volumn 53, Issue 9, 2012, Pages 1832-1839

  Sneck, Mia ^a   Nguyen, Su Duy ^a   Pihlajamaa, Tero ^b   Yohannes, Gebrenegus ^c   Riekkola, Marja Liisa ^c   Milne, Ross ^d   Kovanen, Petri T ^a   Öörni, Katariina ^a  

^a WIHURI RESEARCH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

Aggregation; Apolipoprotein; Atherosclerosis; Low density lipoprotein; Sphingomyelinase

Indexed keywords

APOLIPOPROTEIN B100; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE;

ACIDITY; ALPHA HELIX; ARTICLE; BETA SHEET; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; INCUBATION TEMPERATURE; LIPID HYDROLYSIS; LIPOLYSIS; MICROEMULSION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE DEPENDENCE;

APOLIPOPROTEIN B-100; BACILLUS CEREUS; EMULSIONS; HUMANS; HYDROGEN-ION CONCENTRATION; LIPOLYSIS; LIPOPROTEINS, LDL; PARTICLE SIZE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 84864859102     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M023218     Document Type: Article

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