Platelet-released phospholipids link haemostasis and angiogenesis

Cardiovascular Research

Volumn 49, Issue 3, 2001, Pages 588-599

  English, Denis ^a,b   Garcia, Joe G N ^c   Brindley, D N ^d  

^a METHODIST RESEARCH INSTITUTE   (United States)

^b INDIANA UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Angiogenesis; Endothelial receptors; Hemostasis; Platelets

Indexed keywords

G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDIC ACID; PHOSPHATIDIC ACID; SPHINGOSINE 1 PHOSPHATE;

ANGIOGENESIS; BLOOD CLOTTING; CELL ADHESION; CELL PROLIFERATION; CHEMOTAXIS; HEMOSTASIS; HUMAN; PRIORITY JOURNAL; REVIEW; THROMBOCYTE;

APOPTOSIS; BLOOD PLATELETS; CHEMOTAXIS; ENDOTHELIUM, VASCULAR; GROWTH SUBSTANCES; HEMOSTASIS; HUMANS; ISCHEMIA; LYSOPHOSPHOLIPIDS; NEOVASCULARIZATION, PHYSIOLOGIC; PHOSPHOLIPIDS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SIGNAL TRANSDUCTION; SPHINGOSINE; WOUND HEALING;

EID: 0035895735     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(00)00230-3     Document Type: Review

References (54)

1. Lysophosphatidic acid: G-protein signalling and cellular responses
2. Sphingosine-1-phosphate in cell growth and cell death
3. Sphingosine 1-phosphate: A prototype of a new class of second messengers
4. The bioactive phospholipid lysophosphatidic acid is released from activated platelets
5. An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
6. Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex
7. Molecular cloning of the human Edg2 protein and its identification as a functional receptor for lysophosphatidic acid
8. Identification of cDNAs encoding for two G protein-coupled receptors for lysophospholipids
9. Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid
10. Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6
11. Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid
12. Characterization of a novel sphingosine 1-phosphate receptor, Edg-8
13. Molecular cloning of a high-affinity receptor for the growth factor-like lipid mediator lysophosphatidic acid from Xenopus oocytes
14. Extracellular actions of sphingosine 1-phosphate through endothelial differentiation gene products in mammalian cells: Role in regulating proliferation and apoptosis
15. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
16. Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
17. Sphingosine 1-phosphate signalling through the G-protein-coupled receptor Edg-1
18. 2+ mobilization, Ras-Mitogen-activated protein kinase activation and adenylate cyclase inhibition
19. Activation of endothelial cell phospholipase D by sphingosine and sphingosine-1-phosphate
20. Effects of sphingomyelinase and sphingosine on arterial vasomotor regulation
21. Calcium signalling by G protein-coupled sphingolipid receptors in bovine endothelial cells
22. Sphingosine-1-phosphate: A platelet activating sphingolipid released from agonist-stimulated human platelets
23. Metabolism and functional effects of sphingolipids in blood cells
24. Endothelial cell mitogenesis induced by LPA: Inhibition by thrombospondin-1 and thrombospondin-2
25. 2+ control lysophosphatidate signaling through EDG-2 receptors
26. 2+ in human endothelial cells
27. Upregulation of endothelin-1 production by lysophosphatidic acid in rat aortic endothelial cells
28. Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway
29. Lysophosphatidic acid as a regulator of endothelial/leukocyte interaction
30. Induction and suppression of endothelial cell apoptosis by sphingolipids: A possible in vitro model for cell-cell interactions between platelets and endothelial cells
31. Activation of sphingosine kinase by tumor necrosis factor-α inhibits apoptosis in human endothelial cells
32. Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate
33. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling
34. i-coupled cell surface receptor. Potential involvement in angiogenesis
35. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis
36. Sphingosine 1-phosphate induces angiogenesis: Its angiogenic action and signaling mechanism in human umbilical vein endothelial cells
37. Sphingosine-1-phosphate, a novel second messenger involved in cell growth regulation and signal transduction, affects growth and invasiveness if human breast cancer cells
38. Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action in a pertussis toxin-insensitive manner
39. Sphingosine-1-phosphate, a specific endogenous signaling molecule controlling motility and tumor cell invasiveness
40. Induction of endothelial monolayer permeability by phosphatidate
41. Platelet-derived lysophosphatidic acid decreases endothelial monolayer permeability in vitro
42. Sphingosine-1-phosphate: Extracellular mediator or intracellular second messenger?
43. Mammalian lipid phosphate phosphohydrolases
44. Structural organization of mammalian lipid phosphate phosphatase: Implications for signal transduction
45. Identification of structurally important domains of lipid phosphate phosphatase-1: Implication for its sites of action
46. Sphingosine 1-phosphate released from platelets during clotting accounts for the potent endothelial cell chemotactic activity of blood serum and provides a novel link between angiogenesis and hemostasis
47. Signals to move cells
48. High efficiency transfection of endothelial cells for functional analysis
49. i protein-linked phospholipase C pathway
50. Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis
51. Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing
52. Sphingosine-1-phosphate and lysophosphatidic acid stimulate endothelial cell migration
53. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
54. Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells through the lipid receptors, Edg-1 and Edg-3