The S1P2 receptor expressed in human platelets is linked to the RhoA-Rho kinase pathway and is down regulated in type 2 diabetes

Basic Research in Cardiology

Volumn 104, Issue 3, 2009, Pages 333-340

  Randriamboavonjy, Voahanginirina ^a   Badenhoop, Klaus ^a   Schmidt, Helmut ^a   Geisslinger, Gerd ^a   Fisslthaler, Beate ^a   Fleming, Ingrid ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

calpain; Platelets; Proteases; Signal transduction; Type 2 diabetes

Indexed keywords

CALPAIN; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE 1 PHOSPHATE;

ADULT; ARTICLE; CALCIUM CELL LEVEL; CELL LYSATE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE AGGREGATION; WESTERN BLOTTING;

ADULT; BLOOD PLATELETS; BLOTTING, WESTERN; CALCIUM; DIABETES MELLITUS, TYPE 2; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION; RECEPTORS, LYSOSPHINGOLIPID; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 64949189983     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-008-0769-1     Document Type: Article

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