Sphingosine-1-phosphate phosphatases

Prostaglandins and Other Lipid Mediators

Volumn 64, Issue 1-4, 2001, Pages 143-156

  Mandala, Suzanne M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Lipid phosphohydrolase; Sphingolipid metabolism; Sphingosine 1 phosphate

Indexed keywords

CERAMIDE; G PROTEIN COUPLED RECEPTOR; GLYCOSPHINGOLIPID; LOW DENSITY LIPOPROTEIN; MAGNESIUM ION; N ETHYLMALEIMIDE; PHOSPHATASE; PHOSPHOETHANOLAMINE; PHOSPHOLIPID; SPHINGANINE; SPHINGOSINE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE PHOSPHATASE; SPHINGOSINE DERIVATIVE; SPHINGOSINE KINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; LIPID METABOLISM; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; YEAST CELL;

AMINO ACID SEQUENCE; ANIMALS; LYSOPHOSPHOLIPIDS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHOSPHORIC MONOESTER HYDROLASES; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 0035023404     PISSN: 00906980     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0090-6980(01)00111-3     Document Type: Article

References (56)

1. Merrill AH, Sweeley CC. Sphingolipids: metabolism and cell signalling. In: Vance DE, Vance JE, editors. Biochemistry of Lipids, Lipoproteins and Membranes, Elsevier Science, 1996. p. 309-39.
2. Kolter T., Sandhoff K. Sphingolipids-their metabolic pathways and the pathobiochemistry of neurodegenerative diseases. Angew Chem Int Ed. 38:1999;1532-1568.
3. Riboni L., Viani P., Bassi R., Prinetti A., Tettamanti G. The role of sphingolipids in the process of signal transduction. Prog Lipid Res. 36:1997;153-195.
4. Hannun Y.A. Functions of ceramide in coordinating cellular responses to stress. Science. 274:1996;1855-1859.
5. Mathias S., Pena L.A., Kolesnick R.N. Signal transduction of stress via ceramide. Biochem J. 335:1998;465-480.
6. Dickson R.C., Lester R.L. Metabolism and selected functions of sphingolipids in the yeast Saccharomyces cerevisiae. Biochimica et Biophysica Acta. 1438:1999;305-321.
7. Spiegel S., Merrill A.H. Sphingolipid metabolism and cell growth regulation. FASEB J. 10:1996;1388-1397.
8. Pena L.A., Fuks Z., Kolesnick R. Stress-induced apoptosis and the sphingomyelin pathway. Biochem Pharm. 53:1997;615-621.
9. Spiegel S. Sphingosine 1-phosphate a prototype of a new class of second messengers . J Leukocyte Biol. 65:1999;341-344.
10. Hla T., Lee M.-J., Ancellin N., Liu C.H., Thangada S., Thompson B.D., Kluk M. Sphingosine-1-phosphate extracellular mediator or intracellular second messenger? Biochem Pharm. 58:1999;201-207.
11. Goetzl E.J., An S. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J. 12:1998;1589-1598.
12. Van Brocklyn J.R., Lee M.-J., Menzeleev R., Olivera A., Edsall L., Cuvillier O., Thomas D., Coopman P.J.P., Thangada S., Liu C.H., Hla T., Spiegel S. Dual Actions of sphingosine-1-phosphate extracellular through the Gi-coupled receptor Edg-1 and intracellular to regulate proliferation and survival . J Cell Biol. 142:1998;229-240.
13. Wang F., Van Brocklyn J.R., Edsall L., Nava V.E., Spiegel S. Sphingosine-1-phosphate inhibits motility of human breast cancer cells independently of cell surface receptors. Cancer Res. 59:1999;6185-6191.
14. Hanada K., Nishijima M., Akamatsu Y. A temperature-sensitive mammalian cell mutant with thermolabile serine palmitoyltransferase for the sphingolipid biosynthesis. J Biol Chem. 265:1990;22137-22142.
15. Nagiec M.M., Baltisberger J.A., Wells G.B., Lester R.L., Dickson R.C. The LCB2 gene of Saccharomyces and the related LCB1 gene encode subunits of serine palmitoyltransferase, the initial enzyme in sphingolipid synthesis. PNAS. 91:1994;7899-7902.
16. Zweerink M.M., Edison A.M., Wells G.B., Pinto W., Lester R.L. Characterization of a Novel, Potent, and Specific Inhibitor of Serine Palmitoyltransferase. J Biol Chem. 267:1992;25032-25038.
17. Michel C., van Echten-Deckert G., Rother J., Sandhoff K., Wang E., Merrill A.H. Characterization of ceramide synthesis. J Biol Chem. 267:1992;22432-22437.
18. Wu W.-I., McDonough V.M., Nickels J.T., Ko J., Fischl A.S., Vales T.R., Merrill A.H., Carman G.M. Regulation of lipid biosynthesis in Saccharomyces cerevisiae by fumonisin B1. J Biol Chem. 270:1995;13171-13178.
19. Mandala S.M., Thornton R.A., Frommer B.R., Curotto J.E., Rozdilsky W., Kurtz M.B., Giacobbe R.A., Bills G.F., Cabello M.A., Martin I., Pelaez F., Harris G.H. The discovery of australifungin, a novel inhibitor of sphinganine N-acyltransferase from Sporomiella australis. J Antibiot. 48:1995;349-356.
20. Oh C.-S., Toke D.A., Mandala S., Martin C.E. ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation. J Biol Chem. 272:1997;17376-17384.
21. Van Veldhoven P.P., Mannaerts G.P. Sphingosine-Phosphate Lyase. Adv Lipid Res. 26:1993;69-98.
22. de Ceuster P., Mannaerts G.P., van Veldhoven P.P. Identification and subcellular localization of sphinganine-phosphatases in rat liver. Biochem J. 311:1995;139-146.
23. Van Veldhoven P., Mannaerts G.P. Sphinganine 1-phosphate metabolism in cultured skin fibroblasts evidence for the existence of a sphingosine phosphatase . Biochem J. 299:1994;597-601.
24. Jenkins G.M., Richards A., Wahl T., Mao C., Obeid L., Hannun Y. Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae. J Biol Chem. 272:1997;32566-32572.
25. Nagiec M.M., Skrzypek M., Nagiec E.E., Lester R.L., Dickson R.C. The LCB4 (YOR171c) and LCB5 (YLR260w) genes of Saccharomyces encode long chain base kinases. J Biol Chem. 273:1998;19437-19442.
26. Mandala S.M., Thornton R., Tu Z., Kurtz M.B., Nickels J., Broach J., Menzeleev R., Spiegel S. Sphingoid base 1-phosphate phosphatase A key regulator of sphingolipid metabolism and stress response . Proc Natl Acad Sci USA. 95:1998;150-155.
27. Mao C., Wadleigh M., Jenkins G.M., Hannun Y.A., Obeid L.M. Identification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase. J Biol Chem. 272:1997;28690-28694.
28. Mao C., Saba J.D., Obeid L.M. The Dihydrosphingosine-1-phosphate phosphatases of Saccharomyces cerevisiae are important regulators of cell proliferation and heat stress responses. Biochem J. 342:1999;667-675.
29. Lanterman M.M., Saba J.D. Characterization of sphingosine kinase (SK) activity in Saccharomyces cerevisiae and isolation of SK-deficient mutants. Biochem J. 332:1998;525-531.
30. Skrzypek M.S., Nagiec M.M., Lester R.L., Dickson R.C. Analysis of phosphorylated sphingolipid long-chain bases reveals potential roles in heat stress and growth control in Saccharomyces. J Bacteriology. 181:1999;1134-1140.
31. Merrill A.H., Lingrell S., Wang E., Nikolova-Karakashian M., Vales T.R., Vance D.E. Sphingolipid biosynthesis De Novo by rat hepatocytes in culture. J Biol Chem. 270:1995;13834-13841.
32. Memon R.A., Holleran W.M., Moser A.H., Seki T., Uchida Y., Fuller J., Shigenaga J.K., Grunfeld C., Feingold K.R. Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin. Arterioscler Thromb Vasc Biol. 18:1998;1257-1265.
33. Sandhoff K., Kolter T. Biochemistry of glycosphingolipid degradation. Clin Chim Acta. 266:1997;51-61.
34. Schissel S.L., Schuchman E.H., Williams K.J., Tabas I. Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene. J Biol Chem. 271:1996;18431-18436.
35. Hurwitz R., Ferlinz K., Vielhaber G., Moczall H., Sandhoff K. Processing of human acid sphingomyelinase in normal and I-cell fibroblasts. J Biol Chem. 269:1994;5440-5445.
36. Schmelz E.M., Crall K.J., LaRocque R., Dillehay D.L., Merrill A.H. Uptake and metabolism of sphingolipids in isolated intestinal loops of mice. J Nutr. 124:1994;702-712.
37. Yatomi Y., Yamamura S., Ruan F., Igarashi Y. Sphingosine 1-phosphate induces platelet activation through an extracellular action and shares a platelet surface receptor with lysophosphatidic acid. J Biol Chem. 272:1997;5291-5297.
38. Yang L., Yatomi Y., Miura Y., Satoh K., Ozaki Y. Metabolism and functional effets of sphingolipids in blood cells. Brit J Haematology. 107:1999;282-293.
39. Liu C.H., Thangada S., Lee M.-J., Van Brocklyn J.R., Spiegel S., Hla T. Ligand-induced trafficking of the sphingosine-1-phosphate receptor EDG-1. Mol Biol Cell. 10:1999;1179-1190.
40. Jasinska R., Zhang Q.-X., Pilquil C., Singh I., Xu J., Dewald J., Dillon D.A., Berthiaume L.G., Carman G.M., Waggoner D.W., Brindley D.N. Lipid phosphate phosphohydrolase-1 degrades exogenous glycerolipid and sphingolipid phosphate esters. Biochem J. 340:1999;677-686.
41. Raggers R.J., Van Helvoort A., Evers R., Van Meer G. The human multidrug resistance protein MRP1 translocates sphingolipid analogs across the plasma membrane. J Cell Sci. 112:1999;415-422.
42. Qie L., Nagiec M.M., Baltisberger J.A., Lester R.L., Dickson R.C. Identification of a Saccharomyces gene, LCB3, necessary for incorporation of exogenous long chain bases into sphingolipids. J Biol Chem. 272:1997;16110-16117.
43. Stukey J., Carman G.M. Identification of a novel phosphatase sequence motif. Protein Sci. 6:1997;469-472.
44. Toke DA, Bennett WL, Dillon DA, Wu W-I, Chen X, Ostrander DB, Oshiro J, AC Voelker DR, Fischl AS, Carman GM. Isolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding diacylglycerol pyrophosphate phosphatase. J Biol Chem 1998;273:3278-84.
45. Toke D.A., Bennett W.L., Oshiro J., Wu W.-I., Voelker D.R., Carman G.M. Isolation and characterization of the Saccharomyces cerevisiae LPP1 gene encoding a Mg+-independent phosphatidate phosphatase. J Biol Chem. 273:1998;14331-14338.
46. Van Berkel M.A.A., Rieger M., te Heesen S., Ram A.F.J., van den Ende H., Aebi M., Klis F.M. The Saccharomyces cerevisiae CWH8 gene is required for full levels of dolichol-linked oligosaccharides in the endoplasmic reticulum and for efficient N-glycosylation. Glycobiology. 9:1999;243-253.
47. Atkinson K.D., Jensen B., Kolat A.I., Storm E.M., Henry S.A., Fogel S. Yeast Mutants Auxotrophic for Choline or Ethanolamine. J Bacteriol. 141:1980;558-564.
48. Patton J.L., Srinivasan B., Dickson R.C., Lester R.L. Phenotypes of Sphingolipid-Dependent Strains of Saccharomyces cerevisiae. J Bacteriol. 174:1992;7180-7184.
49. Dickson R.C., Nagiec E.E., Skrzypek M., Tillman P., Wells G.B., Lester R.L. Sphingolipids are potential heat stress signals in Saccharomyces. J Biol Chem. 272:1997;30196-30200.
50. Brindley D.N., Waggoner D.W. Mammalian lipid phosphate phosphohydrolases. J Biol Chem. 273:1998;24281-24284.
51. Mandala SM, Thornton R, Galve-Roperh I, Poulton S, Peterson C, Olivera A, Bergstrom J, Kurtz MB, Spiegel S. Molecular cloning and characterization of a novel lipid phosphohydrolase that degrades sphingosine-1-phosphate and induces cell death. Proc Natl Acad Sci USA 2000;in press.
52. Barila D., Plateroti M., Nobili F., Muda A.O., Xie Y., Morimoto T., Perozzi G. The Dri 42 gene, whose expression is up-regulated during epithelial differentiation, encodes a novel endoplasmic reticulum resident transmembrane protein. J Biol Chem. 271:1996;29928-29936.
53. Zhang Q.-X., Pilquil C.S., Dewald J., Berthiaume L.G., Brindley D.N. Identification of structurally important domains of lipid phosphate phosphatase-1 implications for its sites of action . Biochem J. 345:2000;181-184.
54. English D., Martin M., Harvey K.A., Akard L.P., Allen R., Widlanski T.S., Garcia J.G.N., Siddiqui R.A. Characterization and purification of neutrophil ecto-phosphatidic acid phosphohydrolase. Biochem J. 324:1997;941-950.
55. Waggoner D.W., Martin A., Dewald J., Gomez-Munoz A., Brindley D.N. Purification and characterization of a novel plasma membrane phosphatidate phosphohydrolase from rat liver. J Biol Chem. 270:1995;19422-19429.
56. Waggoner D.W., Xu J., Singh I., Jasinska R., Zhang Q.-X., Brindley D.N. Structural organization of mammalian lipid phosphate phosphatases implications for signal transduction . Biochim Biophys Acta. 1439:1999;299-316.