Tearing down to build up: Metalloenzymes in the biosynthesis lincomycin, hormaomycin and the pyrrolo [1,4]benzodiazepines

Biochimica et Biophysica Acta - Proteins and Proteomics

Volumn 1864, Issue 6, 2016, Pages 724-737

  Colabroy, Keri L ^a  

^a MUHLENBERG COLLEGE   (United States)

Author keywords

Biosynthesis; Dioxygenase; Heme; Hormaomycin; Lincomycin; Metalloenzymes; Pyrrolo 1,4 benzodiazepines

Indexed keywords

3 VINYL 2,3 PYRROLINE 5 CARBOXYLIC ACID; BENZODIAZEPINE DERIVATIVE; DIOXYGENASE; ENZYME; HORMAOMYCIN; LINCOMYCIN; METALLOENZYME DERIVATIVE; PYRROLO[1,4]BENZODIAZEPINE DERIVATIVE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; DEPSIPEPTIDE; METALLOPROTEIN;

BIOSYNTHESIS; DRUG ACTIVITY; DRUG ISOLATION; ENZYME SUBSTRATE; GENOMICS; HYDROXYLATION; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REVIEW; AMINO ACID SEQUENCE; CHEMISTRY; ENZYME SPECIFICITY; METABOLISM; MOLECULAR GENETICS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; BENZODIAZEPINES; DEPSIPEPTIDES; ENZYMES; LINCOMYCIN; METALLOPROTEINS; MOLECULAR SEQUENCE DATA; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 84960336333     PISSN: 15709639     EISSN: 18781454     Source Type: Journal    
DOI: 10.1016/j.bbapap.2016.03.001     Document Type: Review

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