메뉴 건너뛰기




Volumn 6, Issue 9, 2010, Pages

Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data

(14)  Bigham, Abigail a,k   Bauchet, Marc b   Pinto, Dalila c   Mao, Xianyun a   Akey, Joshua M d   Mei, Rui e   Scherer, Stephen W c,f   Julian, Colleen G g   Wilson, Megan J g   Herráez, David López b   Brutsaert, Tom h   Parra, Esteban J i   Moore, Lorna G j   Shriver, Mark D a  


Author keywords

[No Author keywords available]

Indexed keywords

OXYGEN;

EID: 78049419228     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001116     Document Type: Article
Times cited : (449)

References (69)
  • 1
    • 2342424061 scopus 로고    scopus 로고
    • Moving up in the world
    • Aldenderfer M (2003) Moving up in the world. American Scientist 91: 542-549.
    • (2003) American Scientist , vol.91 , pp. 542-549
    • Aldenderfer, M.1
  • 2
    • 75849116319 scopus 로고    scopus 로고
    • Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau
    • Zhao M, Kong QP, Wang HW, Peng MS, Xie XD, et al. (2009) Mitochondrial genome evidence reveals successful Late Paleolithic settlement on the Tibetan Plateau. Proc Natl Acad Sci U S A 106: 21230-21235.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 21230-21235
    • Zhao, M.1    Kong, Q.P.2    Wang, H.W.3    Peng, M.S.4    Xie, X.D.5
  • 4
    • 0034913630 scopus 로고    scopus 로고
    • Human genetic adaptation to high altitude
    • Moore LG (2001) Human genetic adaptation to high altitude. High Alt Med Biol 2: 257-279.
    • (2001) High Alt Med Biol , vol.2 , pp. 257-279
    • Moore, L.G.1
  • 6
    • 0023583847 scopus 로고
    • Hemoglobin concentration of pastoral nomads permanently resident at 4,850-5,450 meters in Tibet
    • Beall CM, Goldstein MC (1987) Hemoglobin concentration of pastoral nomads permanently resident at 4,850-5,450 meters in Tibet. Am J Phys Anthropol 73: 433-438.
    • (1987) Am J Phys Anthropol , vol.73 , pp. 433-438
    • Beall, C.M.1    Goldstein, M.C.2
  • 7
    • 0024588630 scopus 로고
    • Different hematologic responses to hypoxia in Sherpas and Quechua Indians
    • Winslow RM, Chapman KW, Gibson CC, Samaja M, Monge CC, et al. (1989) Different hematologic responses to hypoxia in Sherpas and Quechua Indians. J Appl Physiol 66: 1561-1569.
    • (1989) J Appl Physiol , vol.66 , pp. 1561-1569
    • Winslow, R.M.1    Chapman, K.W.2    Gibson, C.C.3    Samaja, M.4    Monge, C.C.5
  • 8
    • 0027511795 scopus 로고
    • Hypoxic ventilatory responsiveness in Tibetan compared with Han residents of 3,658 m
    • Zhuang J, Droma T, Sun S, Janes C, McCullough RE, et al. (1993) Hypoxic ventilatory responsiveness in Tibetan compared with Han residents of 3,658 m. J Appl Physiol 74: 303-311.
    • (1993) J Appl Physiol , vol.74 , pp. 303-311
    • Zhuang, J.1    Droma, T.2    Sun, S.3    Janes, C.4    McCullough, R.E.5
  • 10
    • 0028125214 scopus 로고
    • Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders
    • Beall CM, Blangero J, Williams-Blangero S, Goldstein MC (1994) Major gene for percent of oxygen saturation of arterial hemoglobin in Tibetan highlanders. Am J Phys Anthropol 95: 271-276.
    • (1994) Am J Phys Anthropol , vol.95 , pp. 271-276
    • Beall, C.M.1    Blangero, J.2    Williams-Blangero, S.3    Goldstein, M.C.4
  • 11
    • 0031259762 scopus 로고    scopus 로고
    • Quantitative genetic analysis of arterial oxygen saturation in Tibetan highlanders
    • Beall CM, Strohl KP, Blangero J, Williams-Blangero S, Decker MJ, et al. (1997) Quantitative genetic analysis of arterial oxygen saturation in Tibetan highlanders. Hum Biol 69: 597-604.
    • (1997) Hum Biol , vol.69 , pp. 597-604
    • Beall, C.M.1    Strohl, K.P.2    Blangero, J.3    Williams-Blangero, S.4    Decker, M.J.5
  • 12
    • 0034466057 scopus 로고    scopus 로고
    • Tibetan and Andean contrasts in adaptation to high-altitude hypoxia
    • Beall CM (2000) Tibetan and Andean contrasts in adaptation to high-altitude hypoxia. Adv Exp Med Biol 475: 63-74.
    • (2000) Adv Exp Med Biol , vol.475 , pp. 63-74
    • Beall, C.M.1
  • 13
    • 0034143526 scopus 로고    scopus 로고
    • Tibetan and Andean patterns of adaptation to high-altitude hypoxia
    • Beall CM (2000) Tibetan and Andean patterns of adaptation to high-altitude hypoxia. Hum Biol 72: 201-228.
    • (2000) Hum Biol , vol.72 , pp. 201-228
    • Beall, C.M.1
  • 14
    • 84934435990 scopus 로고    scopus 로고
    • Finding the genes underlying adaptation to hypoxia using genomic scans for genetic adaptation and admixture mapping
    • Shriver MD, Mei R, Bigham A, Mao X, Brutsaert TD, et al. (2006) Finding the genes underlying adaptation to hypoxia using genomic scans for genetic adaptation and admixture mapping. Adv Exp Med Biol 588: 89-100.
    • (2006) Adv Exp Med Biol , vol.588 , pp. 89-100
    • Shriver, M.D.1    Mei, R.2    Bigham, A.3    Mao, X.4    Brutsaert, T.D.5
  • 15
    • 33845900450 scopus 로고    scopus 로고
    • Convergent adaptation of human lactase persistence in Africa and Europe
    • Tishkoff SA, Reed FA, Ranciaro A, Voight BF, Babbitt CC, et al. (2007) Convergent adaptation of human lactase persistence in Africa and Europe. Nat Genet 39: 31-40.
    • (2007) Nat Genet , vol.39 , pp. 31-40
    • Tishkoff, S.A.1    Reed, F.A.2    Ranciaro, A.3    Voight, B.F.4    Babbitt, C.C.5
  • 16
    • 33847664554 scopus 로고    scopus 로고
    • Genetic evidence for the convergent evolution of light skin in Europeans and East Asians
    • Norton HL, Kittles RA, Parra E, McKeigue P, Mao X, et al. (2007) Genetic evidence for the convergent evolution of light skin in Europeans and East Asians. Mol Biol Evol 24: 710-722.
    • (2007) Mol Biol Evol , vol.24 , pp. 710-722
    • Norton, H.L.1    Kittles, R.A.2    Parra, E.3    McKeigue, P.4    Mao, X.5
  • 17
    • 33749033325 scopus 로고    scopus 로고
    • The genetic architecture of normal variation in human pigmentation: An evolutionary perspective and model
    • McEvoy B, Beleza S, Shriver MD (2006) The genetic architecture of normal variation in human pigmentation: an evolutionary perspective and model. Hum Mol Genet 15 Spec No 2: R176-181.
    • (2006) Hum Mol Genet , vol.15 , Issue.2
    • McEvoy, B.1    Beleza, S.2    Shriver, M.D.3
  • 19
    • 0035320886 scopus 로고    scopus 로고
    • Phenotype-genotype relationships in monogenic disease: Lessons from the thalassaemias
    • Weatherall DJ (2001) Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias. Nat Rev Genet 2: 245-255.
    • (2001) Nat Rev Genet , vol.2 , pp. 245-255
    • Weatherall, D.J.1
  • 20
    • 22544441601 scopus 로고    scopus 로고
    • How malaria has affected the human genome and what human genetics can teach us about malaria
    • Kwiatkowski DP (2005) How malaria has affected the human genome and what human genetics can teach us about malaria. Am J Hum Genet 77: 171-192.
    • (2005) Am J Hum Genet , vol.77 , pp. 171-192
    • Kwiatkowski, D.P.1
  • 21
    • 0035991479 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population
    • Gesang L, Liu G, Cen W, Qiu C, Zhuoma C, et al. (2002) Angiotensinconverting enzyme gene polymorphism and its association with essential hypertension in a Tibetan population. Hypertens Res 25: 481-485.
    • (2002) Hypertens Res , vol.25 , pp. 481-485
    • Gesang, L.1    Liu, G.2    Cen, W.3    Qiu, C.4    Zhuoma, C.5
  • 22
    • 4544222959 scopus 로고    scopus 로고
    • Polymorphisms of renin-angiotensin system genes with high-altitude pulmonary edema in Japanese subjects
    • Hotta J, Hanaoka M, Droma Y, Katsuyama Y, Ota M, et al. (2004) Polymorphisms of renin-angiotensin system genes with high-altitude pulmonary edema in Japanese subjects. Chest 126: 825-830.
    • (2004) Chest , vol.126 , pp. 825-830
    • Hotta, J.1    Hanaoka, M.2    Droma, Y.3    Katsuyama, Y.4    Ota, M.5
  • 23
    • 46249110002 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua
    • Bigham AW, Kiyamu M, Leon-Velarde F, Parra EJ, Rivera-Ch M, et al. (2008) Angiotensin-converting enzyme genotype and arterial oxygen saturation at high altitude in Peruvian Quechua. High Alt Med Biol 9: 167-178.
    • (2008) High Alt Med Biol , vol.9 , pp. 167-178
    • Bigham, A.W.1    Kiyamu, M.2    Leon-Velarde, F.3    Parra, E.J.4    Rivera-Ch, M.5
  • 24
    • 0842291741 scopus 로고    scopus 로고
    • Hypoxia and high altitude. The molecular response
    • Hopfl G, Ogunshola O, Gassmann M (2003) Hypoxia and high altitude. The molecular response. Adv Exp Med Biol 543: 89-115.
    • (2003) Adv Exp Med Biol , vol.543 , pp. 89-115
    • Hopfl, G.1    Ogunshola, O.2    Gassmann, M.3
  • 25
    • 76249086956 scopus 로고    scopus 로고
    • Identifying Positive Selection Candidate Loci for High-Altitude Adaptation in Andean Populations
    • in press
    • Bigham A, Mao X, Brutsaert T, Wilson M, Julian CG, et al. (2010) Identifying Positive Selection Candidate Loci for High-Altitude Adaptation in Andean Populations. Human Genomics 4: in press.
    • (2010) Human Genomics , vol.4
    • Bigham, A.1    Mao, X.2    Brutsaert, T.3    Wilson, M.4    Julian, C.G.5
  • 26
    • 84934438336 scopus 로고    scopus 로고
    • An evolutionary model for identifying genetic adaptation to high altitude
    • Moore LG, Shriver M, Bemis L, Vargas E (2006) An evolutionary model for identifying genetic adaptation to high altitude. Adv Exp Med Biol 588: 101-118.
    • (2006) Adv Exp Med Biol , vol.588 , pp. 101-118
    • Moore, L.G.1    Shriver, M.2    Bemis, L.3    Vargas, E.4
  • 27
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: Analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ (2005) Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21: 263-265.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 28
    • 77951236326 scopus 로고    scopus 로고
    • Genetic variation and recent positive selection in worldwide human populations: Evidence from nearly 1 million SNPs
    • Lopez Herraez D, Bauchet M, Tang K, Theunert C, Pugach I, et al. (2009) Genetic variation and recent positive selection in worldwide human populations: evidence from nearly 1 million SNPs. PLoS ONE 4: e7888.
    • (2009) PLoS ONE , vol.4
    • Lopez Herraez, D.1    Bauchet, M.2    Tang, K.3    Theunert, C.4    Pugach, I.5
  • 30
    • 19944432946 scopus 로고    scopus 로고
    • Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies
    • Tang H, Quertermous T, Rodriguez B, Kardia SL, Zhu X, et al. (2005) Genetic structure, self-identified race/ethnicity, and confounding in case-control association studies. Am J Hum Genet 76: 268-275.
    • (2005) Am J Hum Genet , vol.76 , pp. 268-275
    • Tang, H.1    Quertermous, T.2    Rodriguez, B.3    Kardia, S.L.4    Zhu, X.5
  • 31
    • 0024313579 scopus 로고
    • Statistical method for testing the neutral mutation hypothesis by DNA polymorphism
    • Tajima F (1989) Statistical method for testing the neutral mutation hypothesis by DNA polymorphism. Genetics 123: 585-595.
    • (1989) Genetics , vol.123 , pp. 585-595
    • Tajima, F.1
  • 32
    • 33748676079 scopus 로고    scopus 로고
    • A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations
    • Zhang C, Bailey DK, Awad T, Liu G, Xing G, et al. (2006) A whole genome long-range haplotype (WGLRH) test for detecting imprints of positive selection in human populations. Bioinformatics 22: 2122-2128.
    • (2006) Bioinformatics , vol.22 , pp. 2122-2128
    • Zhang, C.1    Bailey, D.K.2    Awad, T.3    Liu, G.4    Xing, G.5
  • 33
    • 14844285310 scopus 로고    scopus 로고
    • The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs
    • Shriver M, Kennedy GC, Parra EJ, Lawson HA, Huang J, et al. (2004) The genomic distribution of population substructure in four populations using 8,525 autosomal SNPs. Human Genomics 1: 274-286.
    • (2004) Human Genomics , vol.1 , pp. 274-286
    • Shriver, M.1    Kennedy, G.C.2    Parra, E.J.3    Lawson, H.A.4    Huang, J.5
  • 34
    • 4143088044 scopus 로고    scopus 로고
    • Genome scans of DNA variability in humans reveal evidence for selective sweeps outside of Africa
    • Storz JF, Payseur BA, Nachman MW (2004) Genome scans of DNA variability in humans reveal evidence for selective sweeps outside of Africa. Mol Biol Evol 21: 1800-1811.
    • (2004) Mol Biol Evol , vol.21 , pp. 1800-1811
    • Storz, J.F.1    Payseur, B.A.2    Nachman, M.W.3
  • 35
    • 66049157487 scopus 로고    scopus 로고
    • Signals of recent positive selection in a worldwide sample of human populations
    • Pickrell JK, Coop G, Novembre J, Kudaravalli S, Li JZ, et al. (2009) Signals of recent positive selection in a worldwide sample of human populations. Genome Res 19: 826-837.
    • (2009) Genome Res , vol.19 , pp. 826-837
    • Pickrell, J.K.1    Coop, G.2    Novembre, J.3    Kudaravalli, S.4    Li, J.Z.5
  • 37
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, et al. (2006) Global variation in copy number in the human genome. Nature 444: 444-454.
    • (2006) Nature , vol.444 , pp. 444-454
    • Redon, R.1    Ishikawa, S.2    Fitch, K.R.3    Feuk, L.4    Perry, G.H.5
  • 38
    • 38449122025 scopus 로고    scopus 로고
    • Copy-number variation in control population cohorts
    • Pinto D, Marshall C, Feuk L, Scherer SW (2007) Copy-number variation in control population cohorts. Hum Mol Genet 16 Spec No. 2: R168-173.
    • (2007) Hum Mol Genet , vol.16 , Issue.2
    • Pinto, D.1    Marshall, C.2    Feuk, L.3    Scherer, S.W.4
  • 39
    • 77950461601 scopus 로고    scopus 로고
    • Origins and functional impact of copy number variation in the human genome
    • Conrad DF, Pinto D, Redon R, Feuk L, Gokcumen O, et al. (2009) Origins and functional impact of copy number variation in the human genome. Nature 464: 704-712.
    • (2009) Nature , vol.464 , pp. 704-712
    • Conrad, D.F.1    Pinto, D.2    Redon, R.3    Feuk, L.4    Gokcumen, O.5
  • 42
    • 78049440826 scopus 로고
    • Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms
    • Lewontin RC, Krakauer J (1973) Distribution of gene frequency as a test of the theory of the selective neutrality of polymorphisms. Genetics 156: 439-447.
    • (1973) Genetics , vol.156 , pp. 439-447
    • Lewontin, R.C.1    Krakauer, J.2
  • 43
    • 0036911353 scopus 로고    scopus 로고
    • Interrogating a highdensity SNP map for signatures of natural selection
    • Akey JM, Zhang G, Zhang K, Jin L, Shriver MD (2002) Interrogating a highdensity SNP map for signatures of natural selection. Genome Res 12: 1805-1814.
    • (2002) Genome Res , vol.12 , pp. 1805-1814
    • Akey, J.M.1    Zhang, G.2    Zhang, K.3    Jin, L.4    Shriver, M.D.5
  • 44
    • 0029051439 scopus 로고
    • Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
    • Wang GL, Jiang BH, Rue EA, Semenza GL (1995) Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci U S A 92: 5510-5514.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5510-5514
    • Wang, G.L.1    Jiang, B.H.2    Rue, E.A.3    Semenza, G.L.4
  • 45
    • 17944375360 scopus 로고    scopus 로고
    • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
    • Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, et al. (2001) C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107: 43-54.
    • (2001) Cell , vol.107 , pp. 43-54
    • Epstein, A.C.1    Gleadle, J.M.2    McNeill, L.A.3    Hewitson, K.S.4    O'Rourke, J.5
  • 46
    • 0029842459 scopus 로고    scopus 로고
    • Oxygen sensing and molecular adaptation to hypoxia
    • Bunn HF, Poyton RO (1996) Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839-885.
    • (1996) Physiol Rev , vol.76 , pp. 839-885
    • Bunn, H.F.1    Poyton, R.O.2
  • 47
    • 0043234538 scopus 로고    scopus 로고
    • Characterization of the human prolyl 4-hydroxylases that modify the hypoxiainducible factor
    • Hirsila M, Koivunen P, Gunzler V, Kivirikko KI, Myllyharju J (2003) Characterization of the human prolyl 4-hydroxylases that modify the hypoxiainducible factor. J Biol Chem 278: 30772-30780.
    • (2003) J Biol Chem , vol.278 , pp. 30772-30780
    • Hirsila, M.1    Koivunen, P.2    Gunzler, V.3    Kivirikko, K.I.4    Myllyharju, J.5
  • 48
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, et al. (1999) The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399: 271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3    Clifford, S.C.4    Vaux, E.C.5
  • 49
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, et al. (2001) Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 292: 468-472.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.R.2    Tian, Y.M.3    Wilson, M.I.4    Gielbert, J.5
  • 50
    • 0035917313 scopus 로고    scopus 로고
    • HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
    • Ivan M, Kondo K, Yang H, Kim W, Valiando J, et al. (2001) HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292: 464-468.
    • (2001) Science , vol.292 , pp. 464-468
    • Ivan, M.1    Kondo, K.2    Yang, H.3    Kim, W.4    Valiando, J.5
  • 51
    • 36749058977 scopus 로고    scopus 로고
    • Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans
    • Erzurum SC, Ghosh S, Janocha AJ, Xu W, Bauer S, et al. (2007) Higher blood flow and circulating NO products offset high-altitude hypoxia among Tibetans. Proc Natl Acad Sci U S A 104: 17593-17598.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17593-17598
    • Erzurum, S.C.1    Ghosh, S.2    Janocha, A.J.3    Xu, W.4    Bauer, S.5
  • 52
    • 66149133035 scopus 로고    scopus 로고
    • Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth
    • Julian CG, Wilson MJ, Lopez M, Yamashiro H, Tellez W, et al. (2009) Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth. Am J Physiol Regul Integr Comp Physiol.
    • (2009) Am J Physiol Regul Integr Comp Physiol
    • Julian, C.G.1    Wilson, M.J.2    Lopez, M.3    Yamashiro, H.4    Tellez, W.5
  • 54
    • 34548455330 scopus 로고    scopus 로고
    • Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents
    • Wilson MJ, Lopez M, Vargas M, Julian C, Tellez W, et al. (2007) Greater uterine artery blood flow during pregnancy in multigenerational (Andean) than shorter-term (European) high-altitude residents. Am J Physiol Regul Integr Comp Physiol 293: R1313-1324.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.293
    • Wilson, M.J.1    Lopez, M.2    Vargas, M.3    Julian, C.4    Tellez, W.5
  • 55
    • 71749099150 scopus 로고    scopus 로고
    • Genetic adaptation to extreme hypoxia: Study of high-altitude pulmonary edema in a three-generation Han Chinese family
    • Lorenzo VF, Yang Y, Simonson TS, Nussenzveig R, Jorde LB, et al. (2009) Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family. Blood Cells Mol Dis 43: 221-225.
    • (2009) Blood Cells Mol Dis , vol.43 , pp. 221-225
    • Lorenzo, V.F.1    Yang, Y.2    Simonson, T.S.3    Nussenzveig, R.4    Jorde, L.B.5
  • 56
    • 78049432430 scopus 로고    scopus 로고
    • Uterine blood flow as a determinant of feto-placental development
    • In: Burton GJ, Barker DJP, eds, Cambridge: Cambridge University Press. In press
    • Moore LG (2011) Uterine blood flow as a determinant of feto-placental development. In: Burton GJ, Barker DJP, eds. The Placenta and Fetal Programming. Cambridge: Cambridge University Press. In press.
    • (2011) The Placenta and Fetal Programming
    • Moore, L.G.1
  • 57
    • 52949141845 scopus 로고    scopus 로고
    • Integrated detection and population-genetic analysis of SNPs and copy number variation
    • McCarroll SA, Kuruvilla FG, Korn JM, Cawley S, Nemesh J, et al. (2008) Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet 40: 1166-1174.
    • (2008) Nat Genet , vol.40 , pp. 1166-1174
    • McCarroll, S.A.1    Kuruvilla, F.G.2    Korn, J.M.3    Cawley, S.4    Nemesh, J.5
  • 58
    • 0041627923 scopus 로고    scopus 로고
    • Spanish genetic admixture is associated with larger V(O2) max decrement from sea level to 4338 m in Peruvian Quechua
    • Brutsaert TD, Parra EJ, Shriver MD, Gamboa A, Palacios JA, et al. (2003) Spanish genetic admixture is associated with larger V(O2) max decrement from sea level to 4338 m in Peruvian Quechua. J Appl Physiol 95: 519-528.
    • (2003) J Appl Physiol , vol.95 , pp. 519-528
    • Brutsaert, T.D.1    Parra, E.J.2    Shriver, M.D.3    Gamboa, A.4    Palacios, J.A.5
  • 59
    • 0028040151 scopus 로고
    • Mitochondrial DNA analysis in Tibet: Implications for the origin of the Tibetan population and its adaptation to high altitude
    • Torroni A, Miller JA, Moore LG, Zamudio S, Zhuang J, et al. (1994) Mitochondrial DNA analysis in Tibet: implications for the origin of the Tibetan population and its adaptation to high altitude. Am J Phys Anthropol 93: 189-199.
    • (1994) Am J Phys Anthropol , vol.93 , pp. 189-199
    • Torroni, A.1    Miller, J.A.2    Moore, L.G.3    Zamudio, S.4    Zhuang, J.5
  • 60
    • 0038323985 scopus 로고    scopus 로고
    • Skin pigmentation, biogeographical ancestry and admixture mapping
    • Shriver MD, Parra EJ, Dios S, Bonilla C, Norton H, et al. (2003) Skin pigmentation, biogeographical ancestry and admixture mapping. Hum Genet 112: 387-399.
    • (2003) Hum Genet , vol.112 , pp. 387-399
    • Shriver, M.D.1    Parra, E.J.2    Dios, S.3    Bonilla, C.4    Norton, H.5
  • 61
    • 2942711612 scopus 로고    scopus 로고
    • Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city
    • Bonilla C, Shriver MD, Parra EJ, Jones A, Fernandez JR (2004) Ancestral proportions and their association with skin pigmentation and bone mineral density in Puerto Rican women from New York city. Hum Genet 115: 57-68.
    • (2004) Hum Genet , vol.115 , pp. 57-68
    • Bonilla, C.1    Shriver, M.D.2    Parra, E.J.3    Jones, A.4    Fernandez, J.R.5
  • 62
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 63
    • 78049440071 scopus 로고    scopus 로고
    • v1.05 ed
    • Purcell S http://pngu.mgh.harvard.edu/purcell/plink/. v1.05 ed.
    • Purcell, S.1
  • 64
    • 0001677717 scopus 로고
    • Controlling the flase discovery rate: A practical and powerful approach to mulitple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the flase discovery rate: a practical and powerful approach to mulitple testing. Jounral of the Royal Statistical Society 57: 289-300.
    • (1995) Jounral of the Royal Statistical Society , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 65
    • 20944448714 scopus 로고
    • Genetical structure of populations
    • Wright S (1950) Genetical structure of populations. Nature 166: 247-249.
    • (1950) Nature , vol.166 , pp. 247-249
    • Wright, S.1
  • 66
    • 0021566877 scopus 로고
    • Estimating F-statistics for the analysis of population structure
    • Weir BS, Cockerham CC (1984) Estimating F-statistics for the analysis of population structure. Evolution 38: 951-953.
    • (1984) Evolution , vol.38 , pp. 951-953
    • Weir, B.S.1    Cockerham, C.C.2
  • 67
    • 0346991744 scopus 로고    scopus 로고
    • A microsatellite variability screen for positive selection associated with the ''out of Africa'' habitat expansion of Drosophila melanogaster
    • Kauer MO, Dieringer D, Schlotterer C (2003) A microsatellite variability screen for positive selection associated with the ''out of Africa'' habitat expansion of Drosophila melanogaster. Genetics 165: 1137-1148.
    • (2003) Genetics , vol.165 , pp. 1137-1148
    • Kauer, M.O.1    Dieringer, D.2    Schlotterer, C.3
  • 68
    • 0036189674 scopus 로고    scopus 로고
    • A microsatellite-based multilocus screen for the identification of local selective sweeps
    • Schlotterer C (2002) A microsatellite-based multilocus screen for the identification of local selective sweeps. Genetics 160: 753-763.
    • (2002) Genetics , vol.160 , pp. 753-763
    • Schlotterer, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.