Mitochondrial metabolites extend lifespan

Aging Cell

Volumn 15, Issue 2, 2016, Pages 336-348

  Mishur, Robert J ^a,b   Khan, Maruf ^a,b   Munkácsy, Erin ^a,b,c   Sharma, Lokendra ^b   Bokov, Alex ^a   Beam, Haley ^a   Radetskaya, Oxana ^a   Borror, Megan ^a   Lane, Rebecca ^a   Bai, Yidong ^b   Rea, Shane L ^a,b  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c CENTRAL UNIVERSITY OF SOUTH BIHAR   (India)

Author keywords

Caenorhabditis elegans; Aging; EGL 9 PHD; Glutaric acidemia; Hypoxia inducible factor isp 1; Hypoxia inducible factor 1; Jumonji domain containing; Metabolism; Mit mutants; Mitochondria; ketoglutarate dependent hydroxylases

Indexed keywords

2 HYDROXYACID; 2 OXOACID; 2 OXOBUTYRIC ACID; 2 OXOGLUTARIC ACID; 2 OXOISOVALERIC ACID; 2,4 PYRIDINEDICARBOXYLIC ACID; 3 METHYL 2 OXOVALERIC ACID; CARBOXYLIC ACID DERIVATIVE; HISTONE DEMETHYLASE; HYPOXIA INDUCIBLE FACTOR 1; PYRUVIC ACID; UNCLASSIFIED DRUG; VALERIC ACID DERIVATIVE; ALPHA-KETOGLUTARIC ACID; CAENORHABDITIS ELEGANS PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

3T3 CELL LINE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENZYME INHIBITION; HISTONE METHYLATION; IN VITRO STUDY; INTRACELLULAR SIGNALING; LIFE EXTENSION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; WILD TYPE; 3T3-L1 CELL LINE; ANIMAL; LONGEVITY; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

3T3-L1 CELLS; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; KETOGLUTARIC ACIDS; LONGEVITY; MICE; MITOCHONDRIA;

EID: 84960093607     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12439     Document Type: Article

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