Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal

Cell

Volumn 160, Issue 5, 2015, Pages 842-855

  Burkewitz, Kristopher ^a   Morantte, Ianessa ^a   Weir, Heather J M ^a   Yeo, Robin ^a   Zhang, Yue ^a   Huynh, Frank K ^b   Ilkayeva, Olga R ^b   Hirschey, Matthew D ^b   Grant, Ana R ^c   Mair, William B ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CATECHOLAMINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSPHATASE; PROTEIN CRTC 1; PROTEIN NHR 49; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CAENORHABDITIS ELEGANS PROTEIN; CELL RECEPTOR; CRTC-1 PROTEIN, C ELEGANS; NHR-49 PROTEIN, C ELEGANS; TRANSACTIVATOR PROTEIN;

ADULT; AGING; ANIMAL CELL; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; ENERGY TRANSFER; LIFESPAN; LONGEVITY; MITOCHONDRIAL RESPIRATION; NERVOUS SYSTEM; NONHUMAN; NUCLEOTIDE SEQUENCE; PERCEPTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; METABOLISM; MITOCHONDRION; NERVE CELL; PHYSIOLOGY;

CAENORHABDITIS ELEGANS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CATECHOLAMINES; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; LONGEVITY; MITOCHONDRIA; NEURONS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

EID: 84923358396     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.02.004     Document Type: Article

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